For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_2446 (-)

annotation: hypothetical protein MMAR_2446
coordinates: 2953617 - 2955044
length: 475

TTSPPALARVLASTHTSLMHGWVPVTVQVVTAIVLLLAIGWRSRRRLPAAVIFGAIAAWATRWYLGTLAN
EPVPAALWVWVGLTAVAAAMLVVGWRGARWRRRTASLVAVPFCALCAALGLNIWVGYFPTVQAAWNQLSS
GPLPDQADPAAVVAMAGKGVRPAHGSMVPVAIPSNASHFKHRGELVYLPPAWFASYPPPRLPAVMMIGGQ
FNTPADWARAGNAVRTIDDFALAHNGNAPVLVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYMISAF
GVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNAGNKAETITRLFGGNADAWAAFDPT
TVINRHGQYTGISGWFSISVPAGPGAPRDVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDC
AVVPQPGRHDWPFADQVFARALPWLAGQVGTPGVPRIPLPGTASPATQVVPAGR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2446--100% (475)hypothetical protein MMAR_2446
M. marinum MMMAR_0328fbpC2e-0625.00% (256) secreted antigen 85-C FbpC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1666c-0.073.61% (485) hypothetical protein Mb1666c
M. gilvum PYR-GCKMflv_3545-1e-15757.61% (460) putative esterase
M. tuberculosis H37RvRv1639c-0.073.61% (485) hypothetical protein Rv1639c
M. leprae Br4923MLBr_00098fbpC2e-0726.37% (182) antigen 85C, mycolyltransferase
M. abscessus ATCC 19977MAB_1022-1e-14553.33% (465) hypothetical protein MAB_1022
M. avium 104MAV_3129-0.073.10% (461) putative esterase family protein
M. smegmatis MC2 155MSMEG_3797-1e-16559.44% (466) putative esterase family protein
M. thermoresistible (build 8)TH_2468-2e-0626.02% (246) PUTATIVE putative esterase
M. ulcerans Agy99MUL_1625-0.098.53% (475) hypothetical protein MUL_1625
M. vanbaalenii PYR-1Mvan_3331-1e-15959.25% (454) putative esterase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2446|M.marinum_M               ------MTTS-PPALARVLASTHTSLMHGWVPVTVQVVTAIVLLLAIGWR
MUL_1625|M.ulcerans_Agy99           MFDNETVTTS-PPALARVLASTHTSLMHGWVPDTVQVVTAIVLLLAIGWR
Mb1666c|M.bovis_AF2122/97           MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
Rv1639c|M.tuberculosis_H37Rv        MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
MAV_3129|M.avium_104                ------------------------------MPMTVQVLAGVVLTLAVGWR
Mflv_3545|M.gilvum_PYR-GCK          -------------MTLPYLARHDLSLMHGWVPVSVQILAAAAMIAAVGWR
Mvan_3331|M.vanbaalenii_PYR-1       --------------------------MHGWLPVAVQILAVVAVVTAIGRR
MSMEG_3797|M.smegmatis_MC2_155      -----------------MTFTHHLSLMHGWVPTTVQVVTAVILIAAVGRR
MAB_1022|M.abscessus_ATCC_1997      ----------------MRHYIGQLSLIHGWLPMLAQVGTAAVLSYAVYRR
MLBr_00098|M.leprae_Br4923          --------------------------------------------------
TH_2468|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_2446|M.marinum_M               S----RRRLPAAVIFGAIAAWATRWYLG--TLANE--PVPAALWVWVGLT
MUL_1625|M.ulcerans_Agy99           S----RRRLPAAVIFGAIAAWVTRWYLG--TLANE--PVPAALWVWVGLT
Mb1666c|M.bovis_AF2122/97           SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
Rv1639c|M.tuberculosis_H37Rv        SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
MAV_3129|M.avium_104                SRRWRTVWVPVAALAGAAVAYLTHWYIVDRGLSDE--PAPAALWLWVMLT
Mflv_3545|M.gilvum_PYR-GCK          TRRWRRVWVPWAASIGGGLAFTTYCYIRSAGVADESNPAPPTLWVWIALS
Mvan_3331|M.vanbaalenii_PYR-1       TRRWRLVWVPWSALIGVVLAVAAYCYIASAGVADDSNPAPHTLWVWIALS
MSMEG_3797|M.smegmatis_MC2_155      TWRWHLIWLPAAAAVGAVLALGTFWYIQSEGLAG--NPAPRSLWVWIAIS
MAB_1022|M.abscessus_ATCC_1997      SR---LMPVIAGLAMGVVLAAVAYWYLDALGVAGE--PAPPWLWLWIAGI
MLBr_00098|M.leprae_Br4923          --------------------------------------------------
TH_2468|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_2446|M.marinum_M               AVAAAMLVVGWRGARWRRRTASLVAVPFCALCAALGLNIWVGYFPTVQAA
MUL_1625|M.ulcerans_Agy99           AVAAAMLVVGWRGARWRRRTASLVAVPLCALCAALGLNIWVGYFPTVQAA
Mb1666c|M.bovis_AF2122/97           GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
Rv1639c|M.tuberculosis_H37Rv        GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
MAV_3129|M.avium_104                GTAVAVLVLGWRTARRWRRGAAVLAVPLCLLSAALVLNLWVGYFPTVQSA
Mflv_3545|M.gilvum_PYR-GCK          GTAFGVLVAGWRGARRWRRTASALAVPLCALAAALVLNLWVGYFPTVDTA
Mvan_3331|M.vanbaalenii_PYR-1       GFAFGVLVSGWRGARWWRRTAATLAVPLCVLSAALVVNLWVGYFPTVQTA
MSMEG_3797|M.smegmatis_MC2_155      GATVVVLVAGWPRSRWWRRGASALAIPMSVLCAALALNLWVGYFPWVQTA
MAB_1022|M.abscessus_ATCC_1997      GLSAGLTGADWRGVRWWRRSLTVLAIPLCVICAGLSINVWIGYLPTVHSA
MLBr_00098|M.leprae_Br4923          -----------------MRGLSAVVRVLCVAALAVGV-------------
TH_2468|M.thermoresistible__bu      -----------------MNLLSVFFRMMCAAVLAA---------------
                                                      .  : .   :.                     

MMAR_2446|M.marinum_M               WNQLSSGPLPDQADPAAVVAMAGKGVRPAHGSMVPVAIPSNASHFKHRGE
MUL_1625|M.ulcerans_Agy99           WNQLSSGPLPDQADPAAVVAMAGKGVRPAHGSMVPVAIPSNASHFKHRGE
Mb1666c|M.bovis_AF2122/97           WNQLTSGPLPDQADQAAVAALAHSGVRPSHGTLLPVVIPSDASHFKHRGE
Rv1639c|M.tuberculosis_H37Rv        WNQLTSGPLPDQADQAAVAALAHSGVRPSHGTLLPVVIPSDASHFKHRGE
MAV_3129|M.avium_104                WSQLTSGPLPDQTDQATVTAMAASRIRPPHGTVVPVAIPSDGSHFKHRGE
Mflv_3545|M.gilvum_PYR-GCK          WNQLTAGPVPDQTDQVVVAALQKQHAVPIKGSVVPVQIPSTASGFTHRQE
Mvan_3331|M.vanbaalenii_PYR-1       WNQLTAGPLPDQTDAVTVAAMQKQHAMPVKGSLVAVDIPDTASGFRHRQE
MSMEG_3797|M.smegmatis_MC2_155      WNQLTAGPLPDQTDQVTVAAMQRDGAVPAKGTVVPVQIPNTASGFRHRQE
MAB_1022|M.abscessus_ATCC_1997      WARLVLAPVPGEVDRGTVLAMQIAGVQPPSGVVTPVTIPADASGFRHRTE
MLBr_00098|M.leprae_Br4923          --------------FAAAVLLAGTAGNAKAAGYESLMVPSNAMGR-----
TH_2468|M.thermoresistible__bu      ----------------VGVTVSTATATAQPA-VEQLMVPSAAMGR-----
                                                    .   :      .  .    : :*  .        

MMAR_2446|M.marinum_M               LVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRTID
MUL_1625|M.ulcerans_Agy99           LVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRTID
Mb1666c|M.bovis_AF2122/97           LVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKTLD
Rv1639c|M.tuberculosis_H37Rv        LVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKTLD
MAV_3129|M.avium_104                LVYLPPEWFA------TTPPPALPTVMMIGGQFNTPADWTRAGNAVKTID
Mflv_3545|M.gilvum_PYR-GCK          FVYVPPAWFA------SDPPPALPVVMMIGGEFNTPADWLRAGEAVKILD
Mvan_3331|M.vanbaalenii_PYR-1       WVYLPPAWYA------SDPPPALPTVMMIGGEFNTPADWLRAGGAARTLD
MSMEG_3797|M.smegmatis_MC2_155      YVYLPPAWFA------ANPPPKLPTVMMIGGEFNTPADWMRAGNVISTVD
MAB_1022|M.abscessus_ATCC_1997      LVYLPPAWFG------RNPAPRLPAVLMIGSALNTPADWIWAGHATQAAD
MLBr_00098|M.leprae_Br4923          --DIPVAFMAG--------GPHAVYLLDAFNAALDVSNWVTAGNAMTTLG
TH_2468|M.thermoresistible__bu      --DIPVSFMAG--------GPHAVVLLDAFNAAPDVSNWVTVGNAMNTLA
                                       :*  :            *    ::   .     ::*  .* .     

MMAR_2446|M.marinum_M               DFALAHNGNAPVLVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYMIS
MUL_1625|M.ulcerans_Agy99           DFALAHNGNAPVLVFVDSGGAFNNDTERVNGRRGNAADHLTKDVVPYMIS
Mb1666c|M.bovis_AF2122/97           DFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYMVS
Rv1639c|M.tuberculosis_H37Rv        DFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYMVS
MAV_3129|M.avium_104                DFAAAHHGQAPVLVFVDSGGAFNNDTECVNGVRGNAADHLTKDVVPFMIS
Mflv_3545|M.gilvum_PYR-GCK          EFARAHRGYAPVAVFVDPGGTFDNDTECVNGPRGNAADHLVKDVVPYLKS
Mvan_3331|M.vanbaalenii_PYR-1       AFAAAHGGYAPVVVFVDPGGTFNNDTECVNGTRGNSADHLVKDVVPYMKS
MSMEG_3797|M.smegmatis_MC2_155      AFAASHHGFAPVLVFVDPGGAFNNDTECVNGSRGNAADHLTKDVVPYLEA
MAB_1022|M.abscessus_ATCC_1997      DFAAGHGGYAPVLVFADATGAFNNDTECVNGRRGNAADHLVNDVVPYVTS
MLBr_00098|M.leprae_Br4923          GRG--------ISVVAPAGGAYSMYTNWENDGSKQWDTFLSSELPDWLAT
TH_2468|M.thermoresistible__bu      GKG--------ISVVAPAGGAWSLYTNWENDGSKQWETFLANELPDWLAA
                                      .        : *.. . *::.  *:  *.   :   .* .::  :: :

MMAR_2446|M.marinum_M               AFGVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNAGN
MUL_1625|M.ulcerans_Agy99           AFDVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNAGN
Mb1666c|M.bovis_AF2122/97           KFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNAGN
Rv1639c|M.tuberculosis_H37Rv        KFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNAGN
MAV_3129|M.avium_104                AFGVSPHRSNWGVAGWSMGGTCAVDLTVMHPELFSAFVDVAGDFFPNAGN
Mflv_3545|M.gilvum_PYR-GCK          QYGVSPAAAGWGVVGWSMGGTCAVDLTVMHPDIFSTFVDIAGDAAPNAGT
Mvan_3331|M.vanbaalenii_PYR-1       HFGVSSAAANWGVVGWSMGGTCAVDLTVMHPEVFSAFVDIAGDAAPNAGT
MSMEG_3797|M.smegmatis_MC2_155      HYGVSAAAAHWGIVGWSMGGTCAVDLAVMHPDMFSAFVDIAGDLTPNSGT
MAB_1022|M.abscessus_ATCC_1997      NFRVGDDRSQWGVAGWSMGGTCALDLTVMHPETFSAFVDIAGDASPNTGD
MLBr_00098|M.leprae_Br4923          KRGLAPDG--HAAVGASQGGYAALALAAFHPDRFGFAGSLSGFVYPSSTN
TH_2468|M.thermoresistible__bu      NKGLAPGG--HGIVGASQGGTAALTLAAFYPNRYRYAGSMSGFLTPSATA
                                       :.      . .* * ** .*: *:.::*  :    .::*   *.:  

MMAR_2446|M.marinum_M               KAETITR---LFGGNADAWAAFDPTTVINRHGQYTGISGWFSISVPAGPG
MUL_1625|M.ulcerans_Agy99           KAETITR---LFGGNADAWAAFDPTTVINRHGQYTGISGWFSISVPAGPG
Mb1666c|M.bovis_AF2122/97           KTQTIVR---LFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-GPP
Rv1639c|M.tuberculosis_H37Rv        KTQTIVR---LFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-GPP
MAV_3129|M.avium_104                KAQTIAR---LFGGNADAWAAFDPTTVINRHGPYRDVAGWFAISSD-GPP
Mflv_3545|M.gilvum_PYR-GCK          RNETVQR---LFGGDSAAYAAFDPTAVMERHGPYRGVEGWFAVN------
Mvan_3331|M.vanbaalenii_PYR-1       QAETVDR---LFGGDTAAYTSFDPTAVMTRHGPYRGVAGWFDVNGA----
MSMEG_3797|M.smegmatis_MC2_155      KAQTIDR---LFGGNAAAWDAFDPTTVINRHGHYQDVAGWFDVN------
MAB_1022|M.abscessus_ATCC_1997      QKHTIAT---LFGGDEAAWSRFDPATVINHHGRYGSLAGWFDIPGG----
MLBr_00098|M.leprae_Br4923          YNGAILAGLQQFGG-IDGNGMWGAPQLGRWKWHDPYVHASLLAQNN----
TH_2468|M.thermoresistible__bu      LNGAITAGLQRFGG-VETTNMWGLPQAGRWKWRDPDVHAQLLVNNN----
                                       ::      ***       :. .     :     : . :         

MMAR_2446|M.marinum_M               APR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAVVP
MUL_1625|M.ulcerans_Agy99           APR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAVVP
Mb1666c|M.bovis_AF2122/97           SP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAVVP
Rv1639c|M.tuberculosis_H37Rv        SP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAVVP
MAV_3129|M.avium_104                APRRDIQLSDSGAIRLAAREAAANPGNQTAAAYSLCALGRANGIDCAVVP
Mflv_3545|M.gilvum_PYR-GCK          -----------------AVPGAATPNEQAVSAASLCGVGSRSGIACAVVS
Mvan_3331|M.vanbaalenii_PYR-1       ----------------VAVSATAQPNDQAVAASSLCATGGRSGIDCAVVS
MSMEG_3797|M.smegmatis_MC2_155      -----------------TGGPGTAPNDQAKAANSLCTLCSSHGIACAVQA
MAB_1022|M.abscessus_ATCC_1997      MKHRLLTAAGIGSVSDGPHDGIANPEGQDIAANALCGLASAHGIRCAVSA
MLBr_00098|M.leprae_Br4923          -----------TRVWVYSPMTMGG-DIDAMIGQAVASMGSSREFYQQYRS
TH_2468|M.thermoresistible__bu      -----------TRLWVFSPQTLTAADPAAMIGYADQAQGSNRTFYAHYRQ
                                                                   . :         :      

MMAR_2446|M.marinum_M               QPG-RHDWPFADQVFARALPWLAGQVGTPGVPRIPLPGTAS---PATQVV
MUL_1625|M.ulcerans_Agy99           QPG-RHDWPFADQVFARALPWLAGQLGTPGVPRIPLPGTAS---PATQEV
Mb1666c|M.bovis_AF2122/97           QPG-KHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQIA
Rv1639c|M.tuberculosis_H37Rv        QPG-KHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQIA
MAV_3129|M.avium_104                QPG-RHDWPFADRAFAAALPWLAGALGTPGIPRTPLPATSSPAVGAPLVV
Mflv_3545|M.gilvum_PYR-GCK          RPG-NHDWPFASTAFATALPWLAARIGTPGVPQTGFPGTVHG--------
Mvan_3331|M.vanbaalenii_PYR-1       QPG-NHDWPFASTAFTSALPWLAGRIGTPGVPQIDLPRTVSG--------
MSMEG_3797|M.smegmatis_MC2_155      QPG-THDWPFATQAFKASLPWLAGAIGTPDVPVVGLPASAPSAPAFIETG
MAB_1022|M.abscessus_ATCC_1997      QPG-RHDWPFAAQAFDAALPWLAGRLGVPQAARIPLPGLTPE--PSTSVA
MLBr_00098|M.leprae_Br4923          VGGHNGHFDFSGGGDNGWGAWAPQLAAMSGDIVGAIR-------------
TH_2468|M.thermoresistible__bu      IGGRNGHFDFPTSGDHGWSSWGPELGKMSGDLVAAIR-------------
                                      *   .: *.        .* .     .      :              

MMAR_2446|M.marinum_M               PAGR------
MUL_1625|M.ulcerans_Agy99           PAGR------
Mb1666c|M.bovis_AF2122/97           GTGR------
Rv1639c|M.tuberculosis_H37Rv        GTGR------
MAV_3129|M.avium_104                PAERSNTGKR
Mflv_3545|M.gilvum_PYR-GCK          ----------
Mvan_3331|M.vanbaalenii_PYR-1       ----------
MSMEG_3797|M.smegmatis_MC2_155      KTAGPK----
MAB_1022|M.abscessus_ATCC_1997      SSVRAAGS--
MLBr_00098|M.leprae_Br4923          ----------
TH_2468|M.thermoresistible__bu      ----------