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AQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWRSRHWQRRWLPTAAAIGATLAW GTRWYVTGNGLANERPPSTLWIWVALTGAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGY FPTVQTAWNQLTSGPLPDQADQAAVAALAHSGVRPSHGTLLPVVIPSDASHFKHRGELVYLPPAWFDREH RSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKTLDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRR GNAADHLTKDVVPYMVSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNAGNKTQ TIVRLFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSPGPPSPDNAVADTTTMRLAGRDAAANPGNQA AAANALCALGRANGIYCAVVPQPGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTTQQIAGTGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1639c | - | - | 100% (489) | hypothetical protein Rv1639c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1666c | - | 0.0 | 100.00% (489) | hypothetical protein Mb1666c |
| M. gilvum PYR-GCK | Mflv_3545 | - | 1e-164 | 59.70% (464) | putative esterase |
| M. leprae Br4923 | MLBr_00098 | fbpC | 3e-08 | 28.10% (153) | antigen 85C, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_2318c | - | 1e-152 | 55.63% (462) | hypothetical protein MAB_2318c |
| M. marinum M | MMAR_2446 | - | 0.0 | 73.61% (485) | hypothetical protein MMAR_2446 |
| M. avium 104 | MAV_3129 | - | 0.0 | 72.49% (458) | putative esterase family protein |
| M. smegmatis MC2 155 | MSMEG_3797 | - | 1e-171 | 61.35% (458) | putative esterase family protein |
| M. thermoresistible (build 8) | TH_2468 | - | 5e-05 | 26.03% (146) | PUTATIVE putative esterase |
| M. ulcerans Agy99 | MUL_1625 | - | 0.0 | 74.69% (482) | hypothetical protein MUL_1625 |
| M. vanbaalenii PYR-1 | Mvan_3331 | - | 1e-163 | 60.31% (456) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1639c|M.tuberculosis_H37Rv MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
Mb1666c|M.bovis_AF2122/97 MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
MMAR_2446|M.marinum_M ------MTTS-PPALARVLASTHTSLMHGWVPVTVQVVTAIVLLLAIGWR
MUL_1625|M.ulcerans_Agy99 MFDNETVTTS-PPALARVLASTHTSLMHGWVPDTVQVVTAIVLLLAIGWR
MAV_3129|M.avium_104 ------------------------------MPMTVQVLAGVVLTLAVGWR
Mflv_3545|M.gilvum_PYR-GCK -------------MTLPYLARHDLSLMHGWVPVSVQILAAAAMIAAVGWR
Mvan_3331|M.vanbaalenii_PYR-1 --------------------------MHGWLPVAVQILAVVAVVTAIGRR
MSMEG_3797|M.smegmatis_MC2_155 -------------MTFT----HHLSLMHGWVPTTVQVVTAVILIAAVGRR
MAB_2318c|M.abscessus_ATCC_199 ---------------MSAVSGHDISLLHGNFPVSMQVITGFALVIAIGLR
MLBr_00098|M.leprae_Br4923 --------------------------------------------------
TH_2468|M.thermoresistible__bu --------------------------------------------------
Rv1639c|M.tuberculosis_H37Rv SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
Mb1666c|M.bovis_AF2122/97 SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
MMAR_2446|M.marinum_M S----RRRLPAAVIFGAIAAWATRWYLG--TLANE--PVPAALWVWVGLT
MUL_1625|M.ulcerans_Agy99 S----RRRLPAAVIFGAIAAWVTRWYLG--TLANE--PVPAALWVWVGLT
MAV_3129|M.avium_104 SRRWRTVWVPVAALAGAAVAYLTHWYIVDRGLSDE--PAPAALWLWVMLT
Mflv_3545|M.gilvum_PYR-GCK TRRWRRVWVPWAASIGGGLAFTTYCYIRSAGVADESNPAPPTLWVWIALS
Mvan_3331|M.vanbaalenii_PYR-1 TRRWRLVWVPWSALIGVVLAVAAYCYIASAGVADDSNPAPHTLWVWIALS
MSMEG_3797|M.smegmatis_MC2_155 TWRWHLIWLPAAAAVGAVLALGTFWYIQSEGLAG--NPAPRSLWVWIAIS
MAB_2318c|M.abscessus_ATCC_199 TRRWFRRWVPVAVGIGVALAGWAYWYIQSEGWADRGNPAPLMLWVWIALT
MLBr_00098|M.leprae_Br4923 --------------------------------------------------
TH_2468|M.thermoresistible__bu --------------------------------------------------
Rv1639c|M.tuberculosis_H37Rv GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
Mb1666c|M.bovis_AF2122/97 GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
MMAR_2446|M.marinum_M AVAAAMLVVGWRGARWRRRTASLVAVPFCALCAALGLNIWVGYFPTVQAA
MUL_1625|M.ulcerans_Agy99 AVAAAMLVVGWRGARWRRRTASLVAVPLCALCAALGLNIWVGYFPTVQAA
MAV_3129|M.avium_104 GTAVAVLVLGWRTARRWRRGAAVLAVPLCLLSAALVLNLWVGYFPTVQSA
Mflv_3545|M.gilvum_PYR-GCK GTAFGVLVAGWRGARRWRRTASALAVPLCALAAALVLNLWVGYFPTVDTA
Mvan_3331|M.vanbaalenii_PYR-1 GFAFGVLVSGWRGARWWRRTAATLAVPLCVLSAALVVNLWVGYFPTVQTA
MSMEG_3797|M.smegmatis_MC2_155 GATVVVLVAGWPRSRWWRRGASALAIPMSVLCAALALNLWVGYFPWVQTA
MAB_2318c|M.abscessus_ATCC_199 GVAATVLVVGWRTARWWRRAVALTAVPLTILSGSLMLNQWVGYVRSIQSG
MLBr_00098|M.leprae_Br4923 -----------------MRGLSAVVRVLCVAALAVGV-------------
TH_2468|M.thermoresistible__bu -----------------MNLLSVFFRMMCAAVLAA---------------
. : : :
Rv1639c|M.tuberculosis_H37Rv WNQLTSGPLPDQADQAAVAALAHSGVRP--SHGTLLPVVIPSDASHFKHR
Mb1666c|M.bovis_AF2122/97 WNQLTSGPLPDQADQAAVAALAHSGVRP--SHGTLLPVVIPSDASHFKHR
MMAR_2446|M.marinum_M WNQLSSGPLPDQADPAAVVAMAGKGVRP--AHGSMVPVAIPSNASHFKHR
MUL_1625|M.ulcerans_Agy99 WNQLSSGPLPDQADPAAVVAMAGKGVRP--AHGSMVPVAIPSNASHFKHR
MAV_3129|M.avium_104 WSQLTSGPLPDQTDQATVTAMAASRIRP--PHGTVVPVAIPSDGSHFKHR
Mflv_3545|M.gilvum_PYR-GCK WNQLTAGPVPDQTDQVVVAALQKQHAVP--IKGSVVPVQIPSTASGFTHR
Mvan_3331|M.vanbaalenii_PYR-1 WNQLTAGPLPDQTDAVTVAAMQKQHAMP--VKGSLVAVDIPDTASGFRHR
MSMEG_3797|M.smegmatis_MC2_155 WNQLTAGPLPDQTDQVTVAAMQRDGAVP--AKGTVVPVQIPNTASGFRHR
MAB_2318c|M.abscessus_ATCC_199 WAQLTAGPLPNQADMATVTAAREERRGPTMTKGKLVPVDIPADASGFRHR
MLBr_00098|M.leprae_Br4923 ---FAAAVLLAGTAGNAKAAGYESLMVPSNAMGRDIPVAFMAGG------
TH_2468|M.thermoresistible__bu -----VGVTVSTATATAQPA-VEQLMVPSAAMGRDIPVSFMAGG------
. : . * . * * :.* : .
Rv1639c|M.tuberculosis_H37Rv GELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKT
Mb1666c|M.bovis_AF2122/97 GELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKT
MMAR_2446|M.marinum_M GELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRT
MUL_1625|M.ulcerans_Agy99 GELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRT
MAV_3129|M.avium_104 GELVYLPPEWFA------TTPPPALPTVMMIGGQFNTPADWTRAGNAVKT
Mflv_3545|M.gilvum_PYR-GCK QEFVYVPPAWFA------SDPPPALPVVMMIGGEFNTPADWLRAGEAVKI
Mvan_3331|M.vanbaalenii_PYR-1 QEWVYLPPAWYA------SDPPPALPTVMMIGGEFNTPADWLRAGGAART
MSMEG_3797|M.smegmatis_MC2_155 QEYVYLPPAWFA------ANPPPKLPTVMMIGGEFNTPADWMRAGNVIST
MAB_2318c|M.abscessus_ATCC_199 KEIVYLPPAWFD-------STRTELPTIMMIGGEFNTPSDWIRSGNAVEV
MLBr_00098|M.leprae_Br4923 ----------------------PHAVYLLDAFNAALDVSNWVTAGNAMTT
TH_2468|M.thermoresistible__bu ----------------------PHAVVLLDAFNAAPDVSNWVTVGNAMNT
. :: . ::* * .
Rv1639c|M.tuberculosis_H37Rv LDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
Mb1666c|M.bovis_AF2122/97 LDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
MMAR_2446|M.marinum_M IDDFALAHNGNAPVLVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
MUL_1625|M.ulcerans_Agy99 IDDFALAHNGNAPVLVFVDSGGAFNNDTERVNGRRGNAADHLTKDVVPYM
MAV_3129|M.avium_104 IDDFAAAHHGQAPVLVFVDSGGAFNNDTECVNGVRGNAADHLTKDVVPFM
Mflv_3545|M.gilvum_PYR-GCK LDEFARAHRGYAPVAVFVDPGGTFDNDTECVNGPRGNAADHLVKDVVPYL
Mvan_3331|M.vanbaalenii_PYR-1 LDAFAAAHGGYAPVVVFVDPGGTFNNDTECVNGTRGNSADHLVKDVVPYM
MSMEG_3797|M.smegmatis_MC2_155 VDAFAASHHGFAPVLVFVDPGGAFNNDTECVNGSRGNAADHLTKDVVPYL
MAB_2318c|M.abscessus_ATCC_199 ADAFASQHGGNAPVMVFVDAGGSFNNDTECVNGPRGNSADHLTNDVVPFM
MLBr_00098|M.leprae_Br4923 LGGRG--------ISVVAPAGGAYSMYTNWENDGSKQWDTFLSSELPDWL
TH_2468|M.thermoresistible__bu LAGKG--------ISVVAPAGGAWSLYTNWENDGSKQWETFLANELPDWL
. : *.. .**::. *: *. : .* .:: ::
Rv1639c|M.tuberculosis_H37Rv VSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNA
Mb1666c|M.bovis_AF2122/97 VSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNA
MMAR_2446|M.marinum_M ISAFGVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNA
MUL_1625|M.ulcerans_Agy99 ISAFDVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNA
MAV_3129|M.avium_104 ISAFGVSPHRSNWGVAGWSMGGTCAVDLTVMHPELFSAFVDVAGDFFPNA
Mflv_3545|M.gilvum_PYR-GCK KSQYGVSPAAAGWGVVGWSMGGTCAVDLTVMHPDIFSTFVDIAGDAAPNA
Mvan_3331|M.vanbaalenii_PYR-1 KSHFGVSSAAANWGVVGWSMGGTCAVDLTVMHPEVFSAFVDIAGDAAPNA
MSMEG_3797|M.smegmatis_MC2_155 EAHYGVSAAAAHWGIVGWSMGGTCAVDLAVMHPDMFSAFVDIAGDLTPNS
MAB_2318c|M.abscessus_ATCC_199 ISRFGVSPRPQNWGVVGWSMGGTCAVTLAAKHPELFSAFEDIAGDMSPNT
MLBr_00098|M.leprae_Br4923 ATKRGLAPDG--HAAVGASQGGYAALALAAFHPDRFGFAGSLSGFVYPSS
TH_2468|M.thermoresistible__bu AANKGLAPGG--HGIVGASQGGTAALTLAAFYPNRYRYAGSMSGFLTPSA
: .::. . .* * ** .*: *:. :* : .::* *.:
Rv1639c|M.tuberculosis_H37Rv GNKTQTIVR---LFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-G
Mb1666c|M.bovis_AF2122/97 GNKTQTIVR---LFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-G
MMAR_2446|M.marinum_M GNKAETITR---LFGGNADAWAAFDPTTVINRHGQYTGISGWFSISVPAG
MUL_1625|M.ulcerans_Agy99 GNKAETITR---LFGGNADAWAAFDPTTVINRHGQYTGISGWFSISVPAG
MAV_3129|M.avium_104 GNKAQTIAR---LFGGNADAWAAFDPTTVINRHGPYRDVAGWFAISSD-G
Mflv_3545|M.gilvum_PYR-GCK GTRNETVQR---LFGGDSAAYAAFDPTAVMERHGPYRGVEGWFAVN----
Mvan_3331|M.vanbaalenii_PYR-1 GTQAETVDR---LFGGDTAAYTSFDPTAVMTRHGPYRGVAGWFDVNGA--
MSMEG_3797|M.smegmatis_MC2_155 GTKAQTIDR---LFGGNAAAWDAFDPTTVINRHGHYQDVAGWFDVN----
MAB_2318c|M.abscessus_ATCC_199 GNKAQTIAR---LFGGDAGAWEQFDPATVMTRHGRYANTAGWFDVNGLHR
MLBr_00098|M.leprae_Br4923 TNYNGAILAGLQQFGG-IDGNGMWGAPQLGRWKWHDPYVHASLLAQNN--
TH_2468|M.thermoresistible__bu TALNGAITAGLQRFGG-VETTNMWGLPQAGRWKWRDPDVHAQLLVNNN--
:: *** :. . : . : .
Rv1639c|M.tuberculosis_H37Rv PPSP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAV
Mb1666c|M.bovis_AF2122/97 PPSP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAV
MMAR_2446|M.marinum_M PGAPR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAV
MUL_1625|M.ulcerans_Agy99 PGAPR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAV
MAV_3129|M.avium_104 PPAPRRDIQLSDSGAIRLAAREAAANPGNQTAAAYSLCALGRANGIDCAV
Mflv_3545|M.gilvum_PYR-GCK -------------------AVPGAATPNEQAVSAASLCGVGSRSGIACAV
Mvan_3331|M.vanbaalenii_PYR-1 ------------------VAVSATAQPNDQAVAASSLCATGGRSGIDCAV
MSMEG_3797|M.smegmatis_MC2_155 -------------------TGGPGTAPNDQAKAANSLCTLCSSHGIACAV
MAB_2318c|M.abscessus_ATCC_199 AGSG------AITSTGASPGTAANVPLSDQDRAAHKLCEVATAQGIACTV
MLBr_00098|M.leprae_Br4923 -------------TRVWVYSPMTMGG-DIDAMIGQAVASMGSSREFYQQY
TH_2468|M.thermoresistible__bu -------------TRLWVFSPQTLTAADPAAMIGYADQAQGSNRTFYAHY
. . :
Rv1639c|M.tuberculosis_H37Rv VPQPG-KHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQ
Mb1666c|M.bovis_AF2122/97 VPQPG-KHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQ
MMAR_2446|M.marinum_M VPQPG-RHDWPFADQVFARALPWLAGQVGTPGVPRIPLPGTAS---PATQ
MUL_1625|M.ulcerans_Agy99 VPQPG-RHDWPFADQVFARALPWLAGQLGTPGVPRIPLPGTAS---PATQ
MAV_3129|M.avium_104 VPQPG-RHDWPFADRAFAAALPWLAGALGTPGIPRTPLPATSSPAVGAPL
Mflv_3545|M.gilvum_PYR-GCK VSRPG-NHDWPFASTAFATALPWLAARIGTPGVPQTGFPGTVHG------
Mvan_3331|M.vanbaalenii_PYR-1 VSQPG-NHDWPFASTAFTSALPWLAGRIGTPGVPQIDLPRTVSG------
MSMEG_3797|M.smegmatis_MC2_155 QAQPG-THDWPFATQAFKASLPWLAGAIGTPDVPVVGLPASAPSAPAFIE
MAB_2318c|M.abscessus_ATCC_199 QHKPG-EHKWPFAQTAFTSALPWMAGRIGTPTVPDMPLPR----------
MLBr_00098|M.leprae_Br4923 RSVGGHNGHFDFSGGGDNGWGAWAPQLAAMSGDIVGAIR-----------
TH_2468|M.thermoresistible__bu RQIGGRNGHFDFPTSGDHGWSSWGPELGKMSGDLVAAIR-----------
* .: *. .* . . :
Rv1639c|M.tuberculosis_H37Rv IAGTGR------
Mb1666c|M.bovis_AF2122/97 IAGTGR------
MMAR_2446|M.marinum_M VVPAGR------
MUL_1625|M.ulcerans_Agy99 EVPAGR------
MAV_3129|M.avium_104 VVPAERSNTGKR
Mflv_3545|M.gilvum_PYR-GCK ------------
Mvan_3331|M.vanbaalenii_PYR-1 ------------
MSMEG_3797|M.smegmatis_MC2_155 TGKTAGPK----
MAB_2318c|M.abscessus_ATCC_199 ------------
MLBr_00098|M.leprae_Br4923 ------------
TH_2468|M.thermoresistible__bu ------------