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M. thermoresistible (build 8) TH_2468 (-)

annotation: putative esterase
coordinates: 4085813 - 4086706
length: 298

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2468--100% (298)putative esterase
M. thermoresistible (build 8)TH_1961fbpA4e-5540.00% (305) SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A)
M. thermoresistible (build 8)TH_1495fbpA4e-5336.98% (311) SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3833cfbpD1e-11969.58% (286) secreted MPT51/MPB51 antigen protein FBPD (MPT51/MPB51
M. gilvum PYR-GCKMflv_1165-1e-12975.80% (281) putative esterase
M. tuberculosis H37RvRv3803cfbpD1e-11969.58% (286) secreted MPT51/MPB51 antigen protein FBPD (MPT51/MPB51
M. leprae Br4923MLBr_00098fbpC1e-11364.88% (299) antigen 85C, mycolyltransferase
M. abscessus ATCC 19977MAB_0175-4e-5640.95% (315) antigen 85-C precursor
M. marinum MMMAR_5367fbpD1e-12067.55% (302) secreted Mpt51/Mpb51 antigen protein FbpD
M. avium 104MAV_0215-1e-11968.79% (298) antigen 85-C
M. smegmatis MC2 155MSMEG_6396-1e-12571.96% (296) antigen 85-C
M. ulcerans Agy99MUL_4986fbpD1e-11967.22% (302) secreted Mpt51/Mpb51 antigen protein FbpD
M. vanbaalenii PYR-1Mvan_5644-1e-13278.29% (281) putative esterase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3833c|M.bovis_AF2122/97           ------MKGRSALLRALWIAALSFG-LGGVAVAAEPT--AKAAPYENLMV
Rv3803c|M.tuberculosis_H37Rv        ------MKGRSALLRALWIAALSFG-LGGVAVAAEPT--AKAAPYENLMV
MMAR_5367|M.marinum_M               ------MRGVSVVIRLLCVAVLSVT-LGGITVATGSTGKANAAPYETLMV
MUL_4986|M.ulcerans_Agy99           --MEVDMRGVSVVTRLLCVAVLSVT-LGGITVATGSTGKANAAPYETLMV
MLBr_00098|M.leprae_Br4923          ------MRGLSAVVRVLCVAALAVGVFAAAVLLAGTAGNAKAAGYESLMV
MAV_0215|M.avium_104                -MDMTVVRGVSALLRVFCIAVLAAG-LGVALQPAAVTGAARAAGYESLMV
TH_2468|M.thermoresistible__bu      ------MNLLSVFFRMMCAAVLAAV---GVTVSTATA--TAQPAVEQLMV
Mflv_1165|M.gilvum_PYR-GCK          ------MRGMVRAVAAVAMAALFWSGAVAPFTPATPV--ARAQGVEMLMV
Mvan_5644|M.vanbaalenii_PYR-1       ------MHAMLRAIAALTVAV---AAVLAPVT--APT--AGAQGVEMLMV
MSMEG_6396|M.smegmatis_MC2_155      ------MRRGLSLVRALMLTVVLAAGLWTVSATSGAP--ARADGVEYLMV
MAB_0175|M.abscessus_ATCC_1997      MSVRVKARRVLSALLAAFVMPVSMAAAMTINPATAHAFSREGLPVEYLDV
                                           .                                     * * *

Mb3833c|M.bovis_AF2122/97           PSPSMGRDIPVAFLAGGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKG
Rv3803c|M.tuberculosis_H37Rv        PSPSMGRDIPVAFLAGGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKG
MMAR_5367|M.marinum_M               PSGAMGRDIPVAFLAGGPHAAYLLDAFNAGPDVSNWVTAGNAMNTLGGKG
MUL_4986|M.ulcerans_Agy99           PSGAMGRDIPVAFLAGGPHAAYLLDAFNAGPDVSNWVTAGNAMNTLGGKG
MLBr_00098|M.leprae_Br4923          PSNAMGRDIPVAFMAGGPHAVYLLDAFNAALDVSNWVTAGNAMTTLGGRG
MAV_0215|M.avium_104                PSAAMGRDIPVAFLAGGPHAVYLLDAFNAAPDVSNWVTAGNAMNTLGGKG
TH_2468|M.thermoresistible__bu      PSAAMGRDIPVSFMAGGPHAVVLLDAFNAAPDVSNWVTVGNAMNTLAGKG
Mflv_1165|M.gilvum_PYR-GCK          PSAAMGRAIPVAFQGGGPHAVVLLDAFNAAPDVSNWVTAGNAMNTLSGLG
Mvan_5644|M.vanbaalenii_PYR-1       PSAAMGRSIPVAFQGGGPHAVVLLDAFNAAPDVSNWVTAGNAMGTLSGRG
MSMEG_6396|M.smegmatis_MC2_155      PSAAMGRDIPVAFQAGGPHAVFLLDAFNAAPDVSNWVNAGSAMSTLAGRG
MAB_0175|M.abscessus_ATCC_1997      YSNSMGRNIRVEFQGGGPKAVYLLDGLRAQDDFNGWDINTAAFEWFYQSG
                                     * :*** * * * .***:*. ***.:.*  *...*     *:  :   *

Mb3833c|M.bovis_AF2122/97           ISVVAPAGGAYSMYTNWEQDGSK-------QWDTFLSAELPDWLAANRGL
Rv3803c|M.tuberculosis_H37Rv        ISVVAPAGGAYSMYTNWEQDGSK-------QWDTFLSAELPDWLAANRGL
MMAR_5367|M.marinum_M               ISVVAPAGGAFSMYTDWEQDGSK-------QWDTFLSSELPDWLAANKGL
MUL_4986|M.ulcerans_Agy99           ISVVAPAGGAFSMYTDWEQDGSK-------QWDTFLSSELPDWLAANKGL
MLBr_00098|M.leprae_Br4923          ISVVAPAGGAYSMYTNWENDGSK-------QWDTFLSSELPDWLATKRGL
MAV_0215|M.avium_104                ISVVAPAGGAWSMYTNWEQDGSK-------QWDTFLSSELPDWLAANKGL
TH_2468|M.thermoresistible__bu      ISVVAPAGGAWSLYTNWENDGSK-------QWETFLANELPDWLAANKGL
Mflv_1165|M.gilvum_PYR-GCK          ISVAAPAGGAWSMYTNWEQDGSK-------QWETFLADELPNWLAANKGL
Mvan_5644|M.vanbaalenii_PYR-1       ISVAAPAGGAWSMYTNWEQDGSK-------QWETFLADELPNWLAANKGL
MSMEG_6396|M.smegmatis_MC2_155      ISVAAPAGGAWSLYTNWEQDGSK-------QWETFLTAELPGWLAANKGL
MAB_0175|M.abscessus_ATCC_1997      ISVVMPVGGQSSFYTDWYSPSALNKQPYTYKWETFLTQELPAYLATNKQI
                                    ***. *.**  *:**:* . .:        :*:***: *** :**::: :

Mb3833c|M.bovis_AF2122/97           APGGHAAVGAAQGGYGAMALAAFHPDRFGFAGSMSGFLYPSNTTTNGAIA
Rv3803c|M.tuberculosis_H37Rv        APGGHAAVGAAQGGYGAMALAAFHPDRFGFAGSMSGFLYPSNTTTNGAIA
MMAR_5367|M.marinum_M               APGGHAAVGASQGGYGAMALAAFHPDRFGFAGSLSGFLYPSSTTTNGAIL
MUL_4986|M.ulcerans_Agy99           APGGHAAVGASQGGYGAMALAAFHPDRFGFAGSLSGFLYPSSTTTNGAIL
MLBr_00098|M.leprae_Br4923          APDGHAAVGASQGGYAALALAAFHPDRFGFAGSLSGFVYPSSTNYNGAIL
MAV_0215|M.avium_104                APGGHAAVGASQGGYGAMALAAFHPDRFGFAGSLSGFLYPSSTNYNGAIL
TH_2468|M.thermoresistible__bu      APGGHGIVGASQGGTAALTLAAFYPNRYRYAGSMSGFLTPSATALNGAIT
Mflv_1165|M.gilvum_PYR-GCK          APGGHGIVGAAMGGTGALTMATFHPDRYRFAGSLSGFLTPSATAMNGAIT
Mvan_5644|M.vanbaalenii_PYR-1       APNGHAIVGAAQGGTGALTMATFHPDRYRFAGSLSGFLTPSATALNGAIT
MSMEG_6396|M.smegmatis_MC2_155      APDGHAVVGAAQGGTAAVTLAAFHPGMFRFAGSLSGFLTPSATTLNGAIT
MAB_0175|M.abscessus_ATCC_1997      SATGNGVVGLSMSGGAALILAAFHPAQFRFAGSLSGFLNPSTIFMTNAIR
                                    :. *:. ** : .* .*: :*:*:*  : :***:***: **    ..** 

Mb3833c|M.bovis_AF2122/97           AGMQQFGGVDTNGMWGAPQLGRWKWHDPWVHASLLAQNNTRVWVWSP---
Rv3803c|M.tuberculosis_H37Rv        AGMQQFGGVDTNGMWGAPQLGRWKWHDPWVHASLLAQNNTRVWVWSP---
MMAR_5367|M.marinum_M               AGMQQFGGVDGNGMWGAPQLGRWKWHDPWVHAALLAQNNTRVWVWSP---
MUL_4986|M.ulcerans_Agy99           AGMQQFGGVDGNGMWGAPQLGRWKWHDPWVHAALLAQNNTRVWVWSP---
MLBr_00098|M.leprae_Br4923          AGLQQFGGIDGNGMWGAPQLGRWKWHDPYVHASLLAQNNTRVWVYSP---
MAV_0215|M.avium_104                AGLQQYGGVDGNGMWGAPQLGRWKWHDPYVHASLLAQNNTRVWVWSP---
TH_2468|M.thermoresistible__bu      AGLQRFGGVETTNMWGLPQAGRWKWRDPDVHAQLLVNNNTRLWVFSP---
Mflv_1165|M.gilvum_PYR-GCK          DGLARFGGLDIRNMWGLPQLGRWKWHDPDVHSQLLANNNTRLWIYSP---
Mvan_5644|M.vanbaalenii_PYR-1       AGLARFGGVDTRNMWGLPQLGRWKWHDPDVHAQLLVNNNTRLWIYSP---
MSMEG_6396|M.smegmatis_MC2_155      AGLARFGNVDANRMWGPPQFGRWKWHDPAVHVQLLADSNTRLWVYSP---
MAB_0175|M.abscessus_ATCC_1997      VAMLDAGSYSVDNMWGPPWDPAWRRNDPTVQAQALVAAGTRLYIYCAPGG
                                     .:   *. .   *** *    *: .** *:   *.  .**::::..   

Mb3833c|M.bovis_AF2122/97           TNPGASDPAAMIGQAAEAMGN-----SRMFYNQYRSVGGHNGHFDFPASG
Rv3803c|M.tuberculosis_H37Rv        TNPGASDPAAMIGQAAEAMGN-----SRMFYNQYRSVGGHNGHFDFPASG
MMAR_5367|M.marinum_M               TNPGASDPAAMIGQAGAAMGD-----SRSFYQQYRNVGGHNGHFDFPGGG
MUL_4986|M.ulcerans_Agy99           TNPGASDPAAMIGQAGAAMGD-----SRSFYQQYRNVDGHNGHFDFPGGG
MLBr_00098|M.leprae_Br4923          MTMGG-DIDAMIGQAVASMGS-----SREFYQQYRSVGGHNGHFDFSGGG
MAV_0215|M.avium_104                TNMGG-DDAAMIGQAGAAMGS-----SREFYQQYRSNGGHNGHFDFPGGG
TH_2468|M.thermoresistible__bu      QTLTAADPAAMIGYADQAQGS-----NRTFYAHYRQIGGRNGHFDFPTSG
Mflv_1165|M.gilvum_PYR-GCK          GTTTCTDVPAMIGYCDQAQGS-----NRTFYQHYRAVGGSNGHFDFPTSG
Mvan_5644|M.vanbaalenii_PYR-1       ATTTCTDVPAMIGYCDQAQGS-----NRTFYQHYRGIGGGNGHFDFPTSG
MSMEG_6396|M.smegmatis_MC2_155      GTLTCSDPAAMIGYCDQAQGS-----NRQFYSDYRRVGGSNGHFDFPASG
MAB_0175|M.abscessus_ATCC_1997      STPIDDNTDAGVALSASSLESLAVAGNKAFQQAYTAAGGRNANFVFPASG
                                     .    :  * :. .  :  .     .: *   *   .* *.:* *. .*

Mb3833c|M.bovis_AF2122/97           DNGWGSWAPQLGAMSGDIVGAIR-
Rv3803c|M.tuberculosis_H37Rv        DNGWGSWAPQLGAMSGDIVGAIR-
MMAR_5367|M.marinum_M               DNGWGSWSAQLGAMSGDIVGAIR-
MUL_4986|M.ulcerans_Agy99           DNGWGSWSAQLGAMSGDIVGAIR-
MLBr_00098|M.leprae_Br4923          DNGWGAWAPQLAAMSGDIVGAIR-
MAV_0215|M.avium_104                DNGWGSWAGQLGAMSGDIVGAIR-
TH_2468|M.thermoresistible__bu      DHGWSSWGPELGKMSGDLVAAIR-
Mflv_1165|M.gilvum_PYR-GCK          NHDWGSWSGQLAAMTGELVATIR-
Mvan_5644|M.vanbaalenii_PYR-1       NHDWGSWSGQLAAMSGELVATIG-
MSMEG_6396|M.smegmatis_MC2_155      QHDWGSWAPQLAYMSGELVATIK-
MAB_0175|M.abscessus_ATCC_1997      NHSWPYWGQQLQALKGDLIATLNG
                                    ::.*  *. :*  :.*:::.::