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VPMTVQVLAGVVLTLAVGWRSRRWRTVWVPVAALAGAAVAYLTHWYIVDRGLSDEPAPAALWLWVMLTGT AVAVLVLGWRTARRWRRGAAVLAVPLCLLSAALVLNLWVGYFPTVQSAWSQLTSGPLPDQTDQATVTAMA ASRIRPPHGTVVPVAIPSDGSHFKHRGELVYLPPEWFATTPPPALPTVMMIGGQFNTPADWTRAGNAVKT IDDFAAAHHGQAPVLVFVDSGGAFNNDTECVNGVRGNAADHLTKDVVPFMISAFGVSPHRSNWGVAGWSM GGTCAVDLTVMHPELFSAFVDVAGDFFPNAGNKAQTIARLFGGNADAWAAFDPTTVINRHGPYRDVAGWF AISSDGPPAPRRDIQLSDSGAIRLAAREAAANPGNQTAAAYSLCALGRANGIDCAVVPQPGRHDWPFADR AFAAALPWLAGALGTPGIPRTPLPATSSPAVGAPLVVPAERSNTGKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3129 | - | - | 100% (467) | putative esterase family protein |
| M. avium 104 | MAV_0936 | - | e-180 | 67.41% (448) | putative esterase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1666c | - | 0.0 | 72.49% (458) | hypothetical protein Mb1666c |
| M. gilvum PYR-GCK | Mflv_3545 | - | 1e-166 | 61.38% (448) | putative esterase |
| M. tuberculosis H37Rv | Rv1639c | - | 0.0 | 72.49% (458) | hypothetical protein Rv1639c |
| M. leprae Br4923 | MLBr_00098 | fbpC | 2e-05 | 25.18% (139) | antigen 85C, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_2318c | - | 1e-151 | 57.87% (451) | hypothetical protein MAB_2318c |
| M. marinum M | MMAR_2446 | - | 0.0 | 73.10% (461) | hypothetical protein MMAR_2446 |
| M. smegmatis MC2 155 | MSMEG_3797 | - | 1e-168 | 61.78% (450) | putative esterase family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1625 | - | 0.0 | 72.89% (461) | hypothetical protein MUL_1625 |
| M. vanbaalenii PYR-1 | Mvan_3331 | - | 1e-166 | 62.44% (450) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1666c|M.bovis_AF2122/97 MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
Rv1639c|M.tuberculosis_H37Rv MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
MMAR_2446|M.marinum_M ------MTTS-PPALARVLASTHTSLMHGWVPVTVQVVTAIVLLLAIGWR
MUL_1625|M.ulcerans_Agy99 MFDNETVTTS-PPALARVLASTHTSLMHGWVPDTVQVVTAIVLLLAIGWR
MAV_3129|M.avium_104 ------------------------------MPMTVQVLAGVVLTLAVGWR
Mflv_3545|M.gilvum_PYR-GCK -------------MTLPYLARHDLSLMHGWVPVSVQILAAAAMIAAVGWR
Mvan_3331|M.vanbaalenii_PYR-1 --------------------------MHGWLPVAVQILAVVAVVTAIGRR
MSMEG_3797|M.smegmatis_MC2_155 -----------------MTFTHHLSLMHGWVPTTVQVVTAVILIAAVGRR
MAB_2318c|M.abscessus_ATCC_199 ---------------MSAVSGHDISLLHGNFPVSMQVITGFALVIAIGLR
MLBr_00098|M.leprae_Br4923 --------------------------------------------------
Mb1666c|M.bovis_AF2122/97 SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
Rv1639c|M.tuberculosis_H37Rv SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
MMAR_2446|M.marinum_M S----RRRLPAAVIFGAIAAWATRWYLG--TLANE--PVPAALWVWVGLT
MUL_1625|M.ulcerans_Agy99 S----RRRLPAAVIFGAIAAWVTRWYLG--TLANE--PVPAALWVWVGLT
MAV_3129|M.avium_104 SRRWRTVWVPVAALAGAAVAYLTHWYIVDRGLSDE--PAPAALWLWVMLT
Mflv_3545|M.gilvum_PYR-GCK TRRWRRVWVPWAASIGGGLAFTTYCYIRSAGVADESNPAPPTLWVWIALS
Mvan_3331|M.vanbaalenii_PYR-1 TRRWRLVWVPWSALIGVVLAVAAYCYIASAGVADDSNPAPHTLWVWIALS
MSMEG_3797|M.smegmatis_MC2_155 TWRWHLIWLPAAAAVGAVLALGTFWYIQSEGLAG--NPAPRSLWVWIAIS
MAB_2318c|M.abscessus_ATCC_199 TRRWFRRWVPVAVGIGVALAGWAYWYIQSEGWADRGNPAPLMLWVWIALT
MLBr_00098|M.leprae_Br4923 --------------------------------------------------
Mb1666c|M.bovis_AF2122/97 GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
Rv1639c|M.tuberculosis_H37Rv GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
MMAR_2446|M.marinum_M AVAAAMLVVGWRGARWRRRTASLVAVPFCALCAALGLNIWVGYFPTVQAA
MUL_1625|M.ulcerans_Agy99 AVAAAMLVVGWRGARWRRRTASLVAVPLCALCAALGLNIWVGYFPTVQAA
MAV_3129|M.avium_104 GTAVAVLVLGWRTARRWRRGAAVLAVPLCLLSAALVLNLWVGYFPTVQSA
Mflv_3545|M.gilvum_PYR-GCK GTAFGVLVAGWRGARRWRRTASALAVPLCALAAALVLNLWVGYFPTVDTA
Mvan_3331|M.vanbaalenii_PYR-1 GFAFGVLVSGWRGARWWRRTAATLAVPLCVLSAALVVNLWVGYFPTVQTA
MSMEG_3797|M.smegmatis_MC2_155 GATVVVLVAGWPRSRWWRRGASALAIPMSVLCAALALNLWVGYFPWVQTA
MAB_2318c|M.abscessus_ATCC_199 GVAATVLVVGWRTARWWRRAVALTAVPLTILSGSLMLNQWVGYVRSIQSG
MLBr_00098|M.leprae_Br4923 -------------------MRGLSAVVRVLCVAALAVGVFAAAVLLAGTA
. *: .:* :. :.. . :.
Mb1666c|M.bovis_AF2122/97 WNQLTSGPLPDQADQAAVAALAHSGVRP--SHGTLLPVVIPSDASHFKHR
Rv1639c|M.tuberculosis_H37Rv WNQLTSGPLPDQADQAAVAALAHSGVRP--SHGTLLPVVIPSDASHFKHR
MMAR_2446|M.marinum_M WNQLSSGPLPDQADPAAVVAMAGKGVRP--AHGSMVPVAIPSNASHFKHR
MUL_1625|M.ulcerans_Agy99 WNQLSSGPLPDQADPAAVVAMAGKGVRP--AHGSMVPVAIPSNASHFKHR
MAV_3129|M.avium_104 WSQLTSGPLPDQTDQATVTAMAASRIRP--PHGTVVPVAIPSDGSHFKHR
Mflv_3545|M.gilvum_PYR-GCK WNQLTAGPVPDQTDQVVVAALQKQHAVP--IKGSVVPVQIPSTASGFTHR
Mvan_3331|M.vanbaalenii_PYR-1 WNQLTAGPLPDQTDAVTVAAMQKQHAMP--VKGSLVAVDIPDTASGFRHR
MSMEG_3797|M.smegmatis_MC2_155 WNQLTAGPLPDQTDQVTVAAMQRDGAVP--AKGTVVPVQIPNTASGFRHR
MAB_2318c|M.abscessus_ATCC_199 WAQLTAGPLPNQADMATVTAAREERRGPTMTKGKLVPVDIPADASGFRHR
MLBr_00098|M.leprae_Br4923 GNAKAAG--------------YESLMVPSNAMGRDIPVAFMAGG------
::* . * * :.* : .
Mb1666c|M.bovis_AF2122/97 GELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKT
Rv1639c|M.tuberculosis_H37Rv GELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKT
MMAR_2446|M.marinum_M GELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRT
MUL_1625|M.ulcerans_Agy99 GELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRT
MAV_3129|M.avium_104 GELVYLPPEWFA------TTPPPALPTVMMIGGQFNTPADWTRAGNAVKT
Mflv_3545|M.gilvum_PYR-GCK QEFVYVPPAWFA------SDPPPALPVVMMIGGEFNTPADWLRAGEAVKI
Mvan_3331|M.vanbaalenii_PYR-1 QEWVYLPPAWYA------SDPPPALPTVMMIGGEFNTPADWLRAGGAART
MSMEG_3797|M.smegmatis_MC2_155 QEYVYLPPAWFA------ANPPPKLPTVMMIGGEFNTPADWMRAGNVIST
MAB_2318c|M.abscessus_ATCC_199 KEIVYLPPAWFD-------STRTELPTIMMIGGEFNTPSDWIRSGNAVEV
MLBr_00098|M.leprae_Br4923 PHAVYLLDAFNA----------------------ALDVSNWVTAGNAMTT
. **: : ::* :* .
Mb1666c|M.bovis_AF2122/97 LDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
Rv1639c|M.tuberculosis_H37Rv LDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
MMAR_2446|M.marinum_M IDDFALAHNGNAPVLVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
MUL_1625|M.ulcerans_Agy99 IDDFALAHNGNAPVLVFVDSGGAFNNDTERVNGRRGNAADHLTKDVVPYM
MAV_3129|M.avium_104 IDDFAAAHHGQAPVLVFVDSGGAFNNDTECVNGVRGNAADHLTKDVVPFM
Mflv_3545|M.gilvum_PYR-GCK LDEFARAHRGYAPVAVFVDPGGTFDNDTECVNGPRGNAADHLVKDVVPYL
Mvan_3331|M.vanbaalenii_PYR-1 LDAFAAAHGGYAPVVVFVDPGGTFNNDTECVNGTRGNSADHLVKDVVPYM
MSMEG_3797|M.smegmatis_MC2_155 VDAFAASHHGFAPVLVFVDPGGAFNNDTECVNGSRGNAADHLTKDVVPYL
MAB_2318c|M.abscessus_ATCC_199 ADAFASQHGGNAPVMVFVDAGGSFNNDTECVNGPRGNSADHLTNDVVPFM
MLBr_00098|M.leprae_Br4923 LGGRG--------ISVVAPAGGAYSMYTNWENDGSKQWDTFLSSELPDWL
. . : *.. .**::. *: *. : .* .:: ::
Mb1666c|M.bovis_AF2122/97 VSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNA
Rv1639c|M.tuberculosis_H37Rv VSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNA
MMAR_2446|M.marinum_M ISAFGVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNA
MUL_1625|M.ulcerans_Agy99 ISAFDVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNA
MAV_3129|M.avium_104 ISAFGVSPHRSNWGVAGWSMGGTCAVDLTVMHPELFSAFVDVAGDFFPNA
Mflv_3545|M.gilvum_PYR-GCK KSQYGVSPAAAGWGVVGWSMGGTCAVDLTVMHPDIFSTFVDIAGDAAPNA
Mvan_3331|M.vanbaalenii_PYR-1 KSHFGVSSAAANWGVVGWSMGGTCAVDLTVMHPEVFSAFVDIAGDAAPNA
MSMEG_3797|M.smegmatis_MC2_155 EAHYGVSAAAAHWGIVGWSMGGTCAVDLAVMHPDMFSAFVDIAGDLTPNS
MAB_2318c|M.abscessus_ATCC_199 ISRFGVSPRPQNWGVVGWSMGGTCAVTLAAKHPELFSAFEDIAGDMSPNT
MLBr_00098|M.leprae_Br4923 ATKRGLAPDG--HAAVGASQGGYAALALAAFHPDRFGFAGSLSGFVYPSS
: .::. . .* * ** .*: *:. ** *. .::* *.:
Mb1666c|M.bovis_AF2122/97 GNKTQTIVR---LFGGNED-AWSAFDPTTVITRHGSYTGLSGWFAISSP-
Rv1639c|M.tuberculosis_H37Rv GNKTQTIVR---LFGGNED-AWSAFDPTTVITRHGSYTGLSGWFAISSP-
MMAR_2446|M.marinum_M GNKAETITR---LFGGNAD-AWAAFDPTTVINRHGQYTGISGWFSISVPA
MUL_1625|M.ulcerans_Agy99 GNKAETITR---LFGGNAD-AWAAFDPTTVINRHGQYTGISGWFSISVPA
MAV_3129|M.avium_104 GNKAQTIAR---LFGGNAD-AWAAFDPTTVINRHGPYRDVAGWFAISSD-
Mflv_3545|M.gilvum_PYR-GCK GTRNETVQR---LFGGDSA-AYAAFDPTAVMERHGPYRGVEGWFAVN---
Mvan_3331|M.vanbaalenii_PYR-1 GTQAETVDR---LFGGDTA-AYTSFDPTAVMTRHGPYRGVAGWFDVNGA-
MSMEG_3797|M.smegmatis_MC2_155 GTKAQTIDR---LFGGNAA-AWDAFDPTTVINRHGHYQDVAGWFDVN---
MAB_2318c|M.abscessus_ATCC_199 GNKAQTIAR---LFGGDAG-AWEQFDPATVMTRHGRYANTAGWFDVNGLH
MLBr_00098|M.leprae_Br4923 TNYNGAILAGLQQFGGIDGNGMWGAPQLGRWKWHDPYVHASLLAQNNTR-
. :: *** . *. * .
Mb1666c|M.bovis_AF2122/97 GPPSP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCA
Rv1639c|M.tuberculosis_H37Rv GPPSP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCA
MMAR_2446|M.marinum_M GPGAPR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCA
MUL_1625|M.ulcerans_Agy99 GPGAPR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCA
MAV_3129|M.avium_104 GPPAPRRDIQLSDSGAIRLAAREAAANPGNQTAAAYSLCALGRANGIDCA
Mflv_3545|M.gilvum_PYR-GCK --------------------AVPGAATPNEQAVSAASLCGVGSRSGIACA
Mvan_3331|M.vanbaalenii_PYR-1 -------------------VAVSATAQPNDQAVAASSLCATGGRSGIDCA
MSMEG_3797|M.smegmatis_MC2_155 --------------------TGGPGTAPNDQAKAANSLCTLCSSHGIACA
MAB_2318c|M.abscessus_ATCC_199 RAGSG------AITSTGASPGTAANVPLSDQDRAAHKLCEVATAQGIACT
MLBr_00098|M.leprae_Br4923 -----------------VWVYSPMTMGGDIDAMIGQAVASMGSSREFYQQ
. : . :. :
Mb1666c|M.bovis_AF2122/97 VVPQPGK-HDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------Q
Rv1639c|M.tuberculosis_H37Rv VVPQPGK-HDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------Q
MMAR_2446|M.marinum_M VVPQPGR-HDWPFADQVFARALPWLAGQVGTPGVPRIPLPGTAS---PAT
MUL_1625|M.ulcerans_Agy99 VVPQPGR-HDWPFADQVFARALPWLAGQLGTPGVPRIPLPGTAS---PAT
MAV_3129|M.avium_104 VVPQPGR-HDWPFADRAFAAALPWLAGALGTPGIPRTPLPATSSPAVGAP
Mflv_3545|M.gilvum_PYR-GCK VVSRPGN-HDWPFASTAFATALPWLAARIGTPGVPQTGFPGTVH---G--
Mvan_3331|M.vanbaalenii_PYR-1 VVSQPGN-HDWPFASTAFTSALPWLAGRIGTPGVPQIDLPRTVS---G--
MSMEG_3797|M.smegmatis_MC2_155 VQAQPGT-HDWPFATQAFKASLPWLAGAIGTPDVPVVGLPASAP---SAP
MAB_2318c|M.abscessus_ATCC_199 VQHKPGE-HKWPFAQTAFTSALPWMAGRIGTPTVPDMPLPR---------
MLBr_00098|M.leprae_Br4923 YRSVGGHNGHFDFSGGGDNGWGAWAPQLAAMSGDIVGAIR----------
* .: *: .* . . . :
Mb1666c|M.bovis_AF2122/97 QIAGTGR------
Rv1639c|M.tuberculosis_H37Rv QIAGTGR------
MMAR_2446|M.marinum_M QVVPAGR------
MUL_1625|M.ulcerans_Agy99 QEVPAGR------
MAV_3129|M.avium_104 LVVPAERSNTGKR
Mflv_3545|M.gilvum_PYR-GCK -------------
Mvan_3331|M.vanbaalenii_PYR-1 -------------
MSMEG_3797|M.smegmatis_MC2_155 AFIETGKTAGPK-
MAB_2318c|M.abscessus_ATCC_199 -------------
MLBr_00098|M.leprae_Br4923 -------------