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MHGWLPVAVQILAVVAVVTAIGRRTRRWRLVWVPWSALIGVVLAVAAYCYIASAGVADDSNPAPHTLWVW IALSGFAFGVLVSGWRGARWWRRTAATLAVPLCVLSAALVVNLWVGYFPTVQTAWNQLTAGPLPDQTDAV TVAAMQKQHAMPVKGSLVAVDIPDTASGFRHRQEWVYLPPAWYASDPPPALPTVMMIGGEFNTPADWLRA GGAARTLDAFAAAHGGYAPVVVFVDPGGTFNNDTECVNGTRGNSADHLVKDVVPYMKSHFGVSSAAANWG VVGWSMGGTCAVDLTVMHPEVFSAFVDIAGDAAPNAGTQAETVDRLFGGDTAAYTSFDPTAVMTRHGPYR GVAGWFDVNGAVAVSATAQPNDQAVAASSLCATGGRSGIDCAVVSQPGNHDWPFASTAFTSALPWLAGRI GTPGVPQIDLPRTVSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3331 | - | - | 100% (436) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1666c | - | 1e-163 | 60.31% (456) | hypothetical protein Mb1666c |
| M. gilvum PYR-GCK | Mflv_3545 | - | 0.0 | 78.21% (436) | putative esterase |
| M. tuberculosis H37Rv | Rv1639c | - | 1e-163 | 60.31% (456) | hypothetical protein Rv1639c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2318c | - | 1e-154 | 60.27% (448) | hypothetical protein MAB_2318c |
| M. marinum M | MMAR_2446 | - | 1e-159 | 59.25% (454) | hypothetical protein MMAR_2446 |
| M. avium 104 | MAV_3129 | - | 1e-167 | 62.44% (450) | putative esterase family protein |
| M. smegmatis MC2 155 | MSMEG_3797 | - | 0.0 | 67.29% (431) | putative esterase family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1625 | - | 1e-156 | 58.59% (454) | hypothetical protein MUL_1625 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1666c|M.bovis_AF2122/97 MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
Rv1639c|M.tuberculosis_H37Rv MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
MMAR_2446|M.marinum_M ------MTTS-PPALARVLASTHTSLMHGWVPVTVQVVTAIVLLLAIGWR
MUL_1625|M.ulcerans_Agy99 MFDNETVTTS-PPALARVLASTHTSLMHGWVPDTVQVVTAIVLLLAIGWR
MAV_3129|M.avium_104 ------------------------------MPMTVQVLAGVVLTLAVGWR
Mvan_3331|M.vanbaalenii_PYR-1 --------------------------MHGWLPVAVQILAVVAVVTAIGRR
Mflv_3545|M.gilvum_PYR-GCK -------------MTLPYLARHDLSLMHGWVPVSVQILAAAAMIAAVGWR
MSMEG_3797|M.smegmatis_MC2_155 -----------------MTFTHHLSLMHGWVPTTVQVVTAVILIAAVGRR
MAB_2318c|M.abscessus_ATCC_199 ---------------MSAVSGHDISLLHGNFPVSMQVITGFALVIAIGLR
.* ::*::: : * * *
Mb1666c|M.bovis_AF2122/97 SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
Rv1639c|M.tuberculosis_H37Rv SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
MMAR_2446|M.marinum_M S----RRRLPAAVIFGAIAAWATRWYLG--TLANE--PVPAALWVWVGLT
MUL_1625|M.ulcerans_Agy99 S----RRRLPAAVIFGAIAAWVTRWYLG--TLANE--PVPAALWVWVGLT
MAV_3129|M.avium_104 SRRWRTVWVPVAALAGAAVAYLTHWYIVDRGLSDE--PAPAALWLWVMLT
Mvan_3331|M.vanbaalenii_PYR-1 TRRWRLVWVPWSALIGVVLAVAAYCYIASAGVADDSNPAPHTLWVWIALS
Mflv_3545|M.gilvum_PYR-GCK TRRWRRVWVPWAASIGGGLAFTTYCYIRSAGVADESNPAPPTLWVWIALS
MSMEG_3797|M.smegmatis_MC2_155 TWRWHLIWLPAAAAVGAVLALGTFWYIQSEGLAG--NPAPRSLWVWIAIS
MAB_2318c|M.abscessus_ATCC_199 TRRWFRRWVPVAVGIGVALAGWAYWYIQSEGWADRGNPAPLMLWVWIALT
: :* :. * * : *: :. * **:*: ::
Mb1666c|M.bovis_AF2122/97 GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
Rv1639c|M.tuberculosis_H37Rv GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
MMAR_2446|M.marinum_M AVAAAMLVVGWRGARWRRRTASLVAVPFCALCAALGLNIWVGYFPTVQAA
MUL_1625|M.ulcerans_Agy99 AVAAAMLVVGWRGARWRRRTASLVAVPLCALCAALGLNIWVGYFPTVQAA
MAV_3129|M.avium_104 GTAVAVLVLGWRTARRWRRGAAVLAVPLCLLSAALVLNLWVGYFPTVQSA
Mvan_3331|M.vanbaalenii_PYR-1 GFAFGVLVSGWRGARWWRRTAATLAVPLCVLSAALVVNLWVGYFPTVQTA
Mflv_3545|M.gilvum_PYR-GCK GTAFGVLVAGWRGARRWRRTASALAVPLCALAAALVLNLWVGYFPTVDTA
MSMEG_3797|M.smegmatis_MC2_155 GATVVVLVAGWPRSRWWRRGASALAIPMSVLCAALALNLWVGYFPWVQTA
MAB_2318c|M.abscessus_ATCC_199 GVAATVLVVGWRTARWWRRAVALTAVPLTILSGSLMLNQWVGYVRSIQSG
. : :*: ** :* ** .: *:*: *..:* :* ****. :::.
Mb1666c|M.bovis_AF2122/97 WNQLTSGPLPDQADQAAVAALAHSGVRP--SHGTLLPVVIPSDASHFKHR
Rv1639c|M.tuberculosis_H37Rv WNQLTSGPLPDQADQAAVAALAHSGVRP--SHGTLLPVVIPSDASHFKHR
MMAR_2446|M.marinum_M WNQLSSGPLPDQADPAAVVAMAGKGVRP--AHGSMVPVAIPSNASHFKHR
MUL_1625|M.ulcerans_Agy99 WNQLSSGPLPDQADPAAVVAMAGKGVRP--AHGSMVPVAIPSNASHFKHR
MAV_3129|M.avium_104 WSQLTSGPLPDQTDQATVTAMAASRIRP--PHGTVVPVAIPSDGSHFKHR
Mvan_3331|M.vanbaalenii_PYR-1 WNQLTAGPLPDQTDAVTVAAMQKQHAMP--VKGSLVAVDIPDTASGFRHR
Mflv_3545|M.gilvum_PYR-GCK WNQLTAGPVPDQTDQVVVAALQKQHAVP--IKGSVVPVQIPSTASGFTHR
MSMEG_3797|M.smegmatis_MC2_155 WNQLTAGPLPDQTDQVTVAAMQRDGAVP--AKGTVVPVQIPNTASGFRHR
MAB_2318c|M.abscessus_ATCC_199 WAQLTAGPLPNQADMATVTAAREERRGPTMTKGKLVPVDIPADASGFRHR
* **::**:*:*:* ..*.* . * :*.::.* ** .* * **
Mb1666c|M.bovis_AF2122/97 GELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKT
Rv1639c|M.tuberculosis_H37Rv GELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKT
MMAR_2446|M.marinum_M GELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRT
MUL_1625|M.ulcerans_Agy99 GELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRT
MAV_3129|M.avium_104 GELVYLPPEWFA------TTPPPALPTVMMIGGQFNTPADWTRAGNAVKT
Mvan_3331|M.vanbaalenii_PYR-1 QEWVYLPPAWYA------SDPPPALPTVMMIGGEFNTPADWLRAGGAART
Mflv_3545|M.gilvum_PYR-GCK QEFVYVPPAWFA------SDPPPALPVVMMIGGEFNTPADWLRAGEAVKI
MSMEG_3797|M.smegmatis_MC2_155 QEYVYLPPAWFA------ANPPPKLPTVMMIGGEFNTPADWMRAGNVIST
MAB_2318c|M.abscessus_ATCC_199 KEIVYLPPAWFD-------STRTELPTIMMIGGEFNTPSDWIRSGNAVEV
* **:** *: . . **.:*****:****:** *:* .
Mb1666c|M.bovis_AF2122/97 LDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
Rv1639c|M.tuberculosis_H37Rv LDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
MMAR_2446|M.marinum_M IDDFALAHNGNAPVLVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
MUL_1625|M.ulcerans_Agy99 IDDFALAHNGNAPVLVFVDSGGAFNNDTERVNGRRGNAADHLTKDVVPYM
MAV_3129|M.avium_104 IDDFAAAHHGQAPVLVFVDSGGAFNNDTECVNGVRGNAADHLTKDVVPFM
Mvan_3331|M.vanbaalenii_PYR-1 LDAFAAAHGGYAPVVVFVDPGGTFNNDTECVNGTRGNSADHLVKDVVPYM
Mflv_3545|M.gilvum_PYR-GCK LDEFARAHRGYAPVAVFVDPGGTFDNDTECVNGPRGNAADHLVKDVVPYL
MSMEG_3797|M.smegmatis_MC2_155 VDAFAASHHGFAPVLVFVDPGGAFNNDTECVNGSRGNAADHLTKDVVPYL
MAB_2318c|M.abscessus_ATCC_199 ADAFASQHGGNAPVMVFVDAGGSFNNDTECVNGPRGNSADHLTNDVVPFM
* ** * * *** ****.**:*:**** *** ***:****.:****::
Mb1666c|M.bovis_AF2122/97 VSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNA
Rv1639c|M.tuberculosis_H37Rv VSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNA
MMAR_2446|M.marinum_M ISAFGVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNA
MUL_1625|M.ulcerans_Agy99 ISAFDVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNA
MAV_3129|M.avium_104 ISAFGVSPHRSNWGVAGWSMGGTCAVDLTVMHPELFSAFVDVAGDFFPNA
Mvan_3331|M.vanbaalenii_PYR-1 KSHFGVSSAAANWGVVGWSMGGTCAVDLTVMHPEVFSAFVDIAGDAAPNA
Mflv_3545|M.gilvum_PYR-GCK KSQYGVSPAAAGWGVVGWSMGGTCAVDLTVMHPDIFSTFVDIAGDAAPNA
MSMEG_3797|M.smegmatis_MC2_155 EAHYGVSAAAAHWGIVGWSMGGTCAVDLAVMHPDMFSAFVDIAGDLTPNS
MAB_2318c|M.abscessus_ATCC_199 ISRFGVSPRPQNWGVVGWSMGGTCAVTLAAKHPELFSAFEDIAGDMSPNT
: :.**. **:.********** *:. ** :**:* *:*** **:
Mb1666c|M.bovis_AF2122/97 GNKTQTIVRLFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-GPPS
Rv1639c|M.tuberculosis_H37Rv GNKTQTIVRLFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-GPPS
MMAR_2446|M.marinum_M GNKAETITRLFGGNADAWAAFDPTTVINRHGQYTGISGWFSISVPAGPGA
MUL_1625|M.ulcerans_Agy99 GNKAETITRLFGGNADAWAAFDPTTVINRHGQYTGISGWFSISVPAGPGA
MAV_3129|M.avium_104 GNKAQTIARLFGGNADAWAAFDPTTVINRHGPYRDVAGWFAISSD-GPPA
Mvan_3331|M.vanbaalenii_PYR-1 GTQAETVDRLFGGDTAAYTSFDPTAVMTRHGPYRGVAGWFDVNGA-----
Mflv_3545|M.gilvum_PYR-GCK GTRNETVQRLFGGDSAAYAAFDPTAVMERHGPYRGVEGWFAVN-------
MSMEG_3797|M.smegmatis_MC2_155 GTKAQTIDRLFGGNAAAWDAFDPTTVINRHGHYQDVAGWFDVN-------
MAB_2318c|M.abscessus_ATCC_199 GNKAQTIARLFGGDAGAWEQFDPATVMTRHGRYANTAGWFDVNGLHRAGS
*.: :*: *****: *: ***::*: *** * . *** :.
Mb1666c|M.bovis_AF2122/97 P--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAVVPQ
Rv1639c|M.tuberculosis_H37Rv P--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAVVPQ
MMAR_2446|M.marinum_M PR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAVVPQ
MUL_1625|M.ulcerans_Agy99 PR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAVVPQ
MAV_3129|M.avium_104 PRRDIQLSDSGAIRLAAREAAANPGNQTAAAYSLCALGRANGIDCAVVPQ
Mvan_3331|M.vanbaalenii_PYR-1 ---------------VAVSATAQPNDQAVAASSLCATGGRSGIDCAVVSQ
Mflv_3545|M.gilvum_PYR-GCK ----------------AVPGAATPNEQAVSAASLCGVGSRSGIACAVVSR
MSMEG_3797|M.smegmatis_MC2_155 ----------------TGGPGTAPNDQAKAANSLCTLCSSHGIACAVQAQ
MAB_2318c|M.abscessus_ATCC_199 G------AITSTGASPGTAANVPLSDQDRAAHKLCEVATAQGIACTVQHK
. .:* :* ** ** *:* :
Mb1666c|M.bovis_AF2122/97 PGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQIAGT
Rv1639c|M.tuberculosis_H37Rv PGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQIAGT
MMAR_2446|M.marinum_M PGRHDWPFADQVFARALPWLAGQVGTPGVPRIPLPGTAS---PATQVVPA
MUL_1625|M.ulcerans_Agy99 PGRHDWPFADQVFARALPWLAGQLGTPGVPRIPLPGTAS---PATQEVPA
MAV_3129|M.avium_104 PGRHDWPFADRAFAAALPWLAGALGTPGIPRTPLPATSSPAVGAPLVVPA
Mvan_3331|M.vanbaalenii_PYR-1 PGNHDWPFASTAFTSALPWLAGRIGTPGVPQIDLPRTVS---G-------
Mflv_3545|M.gilvum_PYR-GCK PGNHDWPFASTAFATALPWLAARIGTPGVPQTGFPGTVH---G-------
MSMEG_3797|M.smegmatis_MC2_155 PGTHDWPFATQAFKASLPWLAGAIGTPDVPVVGLPASAP---SAPAFIET
MAB_2318c|M.abscessus_ATCC_199 PGEHKWPFAQTAFTSALPWMAGRIGTPTVPDMPLPR--------------
** *.**** .* :***:*. :.** :* :*
Mb1666c|M.bovis_AF2122/97 GR------
Rv1639c|M.tuberculosis_H37Rv GR------
MMAR_2446|M.marinum_M GR------
MUL_1625|M.ulcerans_Agy99 GR------
MAV_3129|M.avium_104 ERSNTGKR
Mvan_3331|M.vanbaalenii_PYR-1 --------
Mflv_3545|M.gilvum_PYR-GCK --------
MSMEG_3797|M.smegmatis_MC2_155 GKTAGPK-
MAB_2318c|M.abscessus_ATCC_199 --------