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MNASAEHIRYEKRGRIATITLDRPASRNAIDPAMDRRLRDIWAEFRDDDGVDVAILTGAGEAFCAGADRN TWFHQWLDADAAVVRRNAKGVGFGGITRGLHRITKPVIGAVNGWALGAGLELALACDIRIASERAMFGVP LVGLGFHHGDGGISRLVDTCGLAVALDLELSGEPIDAQRALQVNLVTRVVAHDDLMTAAHALAERIAGYH QAAVRSAKDTVLDVVGRPLDEQLEREAMSAYSIDRHSAREIIAAVGMRGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0148 | - | - | 100% (260) | enoyl-CoA hydratase/isomerase |
| M. avium 104 | MAV_2597 | - | 6e-33 | 41.63% (209) | carnitinyl-CoA dehydratase |
| M. avium 104 | MAV_1195 | - | 2e-31 | 38.43% (216) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0694 | echA5 | 1e-33 | 36.47% (255) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2117 | - | 5e-34 | 40.08% (237) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv0675 | echA5 | 1e-33 | 36.47% (255) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-29 | 37.68% (207) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 1e-31 | 35.45% (220) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4396 | echA8 | 6e-32 | 38.74% (222) | enoyl-CoA hydratase EchA8 |
| M. smegmatis MC2 155 | MSMEG_5198 | - | 1e-34 | 41.63% (209) | carnitinyl-CoA dehydratase |
| M. thermoresistible (build 8) | TH_2627 | - | 6e-30 | 36.10% (241) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 4e-32 | 38.74% (222) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4588 | - | 2e-32 | 40.67% (209) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2117|M.gilvum_PYR-GCK -------MAPGALTERRGNVLIITINRPEARNAINASVSIAVGDALQAAQ
Mvan_4588|M.vanbaalenii_PYR-1 MTDTVTDTAPGALTERRGNVLIITINRPEARNAVNASVSIGVGNALQAAQ
MSMEG_5198|M.smegmatis_MC2_155 ----MTETAPGALTERRGNVLLITINRPEARNAINSSVSQAVGDALAEAQ
MAB_0836c|M.abscessus_ATCC_199 -----MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWDEID
MMAR_4396|M.marinum_M ------MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELD
MUL_0210|M.ulcerans_Agy99 ------MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELD
MLBr_02402|M.leprae_Br4923 ------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELD
MAV_0148|M.avium_104 ----MNASAEHIRYEKRGRIATITLDRPASRNAIDPAMDRRLRDIWAEFR
Mb0694|M.bovis_AF2122/97 -------MSDLVRVERKGRVTTVILNRPASRNAVNGPTAAALCAAFEQFD
Rv0675|M.tuberculosis_H37Rv -------MSDLVRVERKGRVTTVILNRPASRNAVNGPTAAALCAAFEQFD
TH_2627|M.thermoresistible__bu -------MTKPVRIERDGPVTTVIIDRPEARNAVNGPTAAALYAAFDEFD
: : : ::** **:. .
Mflv_2117|M.gilvum_PYR-GCK EDPDVRAVILTGAGDKSFCAGADLKA-----ISRGENLFHPEHSEWGFAG
Mvan_4588|M.vanbaalenii_PYR-1 DDPEIRAVILTGAGDKSFCAGADLKA-----ISRGENLFHPEHTEWGFAG
MSMEG_5198|M.smegmatis_MC2_155 NDPEVRAVVLTGAGDKSFCAGADLKA-----ISRGENLFHPEHPEYGFAG
MAB_0836c|M.abscessus_ATCC_199 HDDGIRAAILTGAG-SAYCVGGDLSDGW---MVRDGSAPPLDPATIGKGL
MMAR_4396|M.marinum_M NDPGIGAIIITGSA-KAFAAGADIKE------MADLTFSEAFDADFFAAW
MUL_0210|M.ulcerans_Agy99 NDPGIGAIIITGSA-KAFAAGADIKE------MADLTFSEAFDADFFAAW
MLBr_02402|M.leprae_Br4923 IDPDVGAILITGSP-KVFAAGADIKE------MASLTFTDAFDADFFSAW
MAV_0148|M.avium_104 DDDGVDVAILTGAG-EAFCAGADRNTWFHQWLDADAAVVRRNAKGVGFGG
Mb0694|M.bovis_AF2122/97 RDDAASVAVLWGAG-GTFCAGADLKAFG------TPEANSVHRTGPGPMG
Rv0675|M.tuberculosis_H37Rv RDDAASVAVLWGAG-GTFCAGADLKAFG------TPEANSVHRTGPGPMG
TH_2627|M.thermoresistible__bu RDEDAAVAVLWGAN-GTFCAGADLKAFG------TPEANPVHRSGPGPMG
* . :: *: :..*.* .
Mflv_2117|M.gilvum_PYR-GCK YVR--HFIDKPTIAAVNGTALGGGTELALASDLVVAEERAKFGLPEVKRG
Mvan_4588|M.vanbaalenii_PYR-1 YVR--HFIDKPTIAAVNGTALGGGTELALASDLVVAEERAKFGLPEVKRG
MSMEG_5198|M.smegmatis_MC2_155 YVS--HFIDKPTIAAVNGTALGGGTELALASDLVVAEERAMFGLPEVKRG
MAB_0836c|M.abscessus_ATCC_199 LLS--HTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRG
MMAR_4396|M.marinum_M GKL--AAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLG
MUL_0210|M.ulcerans_Agy99 GKL--AAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLG
MLBr_02402|M.leprae_Br4923 GKL--AAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLG
MAV_0148|M.avium_104 ITRGLHRITKPVIGAVNGWALGAGLELALACDIRIASERAMFGVPLVGLG
Mb0694|M.bovis_AF2122/97 PSR--MMLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWG
Rv0675|M.tuberculosis_H37Rv PSR--MMLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWG
TH_2627|M.thermoresistible__bu PTR--MVLSKPVIAAVSGYAVAGGLELALWTDLRIVEQDAIMGVFCRRWG
: .* *.** * .:..* *: *: : : * :* *
Mflv_2117|M.gilvum_PYR-GCK LIAGAGGVFRIVEQLPRKVALELIYTGEPISSADALRWGLINQVVPDGTV
Mvan_4588|M.vanbaalenii_PYR-1 LIAGAGGVFRIVEQLPRKVALELIYTGEPISSADALRWGLINQVVPDGTV
MSMEG_5198|M.smegmatis_MC2_155 LIAGAGGVFRIIEQLPRKVALELVYTGDPISAADALKWGLINQVVPDGTV
MAB_0836c|M.abscessus_ATCC_199 LVPGAGSMVRLKRQIPYTKAMEMILTGEPLTAFEAYHFGLVGHVVPAGTA
MMAR_4396|M.marinum_M VLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDL
MUL_0210|M.ulcerans_Agy99 VLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDL
MLBr_02402|M.leprae_Br4923 VLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDL
MAV_0148|M.avium_104 FHHGDGGISRLVDTCGLAVALDLELSGEPIDAQRALQVNLVTRVVAHDDL
Mb0694|M.bovis_AF2122/97 VPLIDGGTVRLPRLIGHSRAMDMILTGRGVPADEALAMGLANRVVPKGQA
Rv0675|M.tuberculosis_H37Rv VPLIDGGTVRLPRLIGHSRAMDMILTGRGVPADEALAMGLANRVVPKGQA
TH_2627|M.thermoresistible__bu VPLIDGGTVRLPRLIGESRAMDLILTGRPVDADEALAIGLANRVVPTGEA
. *. *: *::: :* : : * .* :** .
Mflv_2117|M.gilvum_PYR-GCK VDAALALAERITCNAPLAVRASKRVSYGAIDGVVGSDEPFWKQTFSEFST
Mvan_4588|M.vanbaalenii_PYR-1 VDAALALAERITCNAPLAVQASKRVSYGAVDGVVGSEEPFWKQTFGEFST
MSMEG_5198|M.smegmatis_MC2_155 VDAALALAERITCNAPLAVQASKRVAYGAEEGTVPAEQPSWKRTNREFVT
MAB_0836c|M.abscessus_ATCC_199 LDKARSLADRIVRNGPLAVRNAKEA---IVRSGWLAEEDARAIEARLTRP
MMAR_4396|M.marinum_M LTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEG---LLYERRLIHS
MUL_0210|M.ulcerans_Agy99 LTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEG---LLYERRLIHS
MLBr_02402|M.leprae_Br4923 LPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEG---LLHERRLFHS
MAV_0148|M.avium_104 MTAAHALAERIAGYHQAAVRSAKDTVLDVVGRPLDEQ----LEREAMSAY
Mb0694|M.bovis_AF2122/97 RQAAEELAAQLAALPQQCLRSDRLSALHQWGLPESAALDLEFASIARVAG
Rv0675|M.tuberculosis_H37Rv RQAAEELAAQLAALPQQCLRSDRLSALHQWGLPESAALDLEFASIARVAG
TH_2627|M.thermoresistible__bu RARAEELAAELARLPQQCLRADRMSVLQQWGKREAEAMDFEFASISKVSH
* :* : . : :
Mflv_2117|M.gilvum_PYR-GCK LLKTEDAMEGPLAFAQKREPVWKAK----
Mvan_4588|M.vanbaalenii_PYR-1 LLKTEDAMEGPLAFAQKREPVWKAK----
MSMEG_5198|M.smegmatis_MC2_155 LLKTEDAMEGPLAFAQKRQPVWKAK----
MAB_0836c|M.abscessus_ATCC_199 VITSADAREGLAAFKEKREARFTGR----
MMAR_4396|M.marinum_M AFATADQSEGMAAFIEKRPPNFTHR----
MUL_0210|M.ulcerans_Agy99 AFATADQSEGMAAFIEKRPPNFTHR----
MLBr_02402|M.leprae_Br4923 TFVTDDQSEGMAAFIEKRAPQFTHR----
MAV_0148|M.avium_104 SIDRHSAREIIAAVGMRGH----------
Mb0694|M.bovis_AF2122/97 EALEGARRFAAGAGRHGAPAPRAEQGDTL
Rv0675|M.tuberculosis_H37Rv EALEGARRFAAGAGRHGAPAPRAEQGDTL
TH_2627|M.thermoresistible__bu EAAAGASRFAAGAGRHGAPA---------
*