For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VGSWYSREVVSEHLNLYREIHADSFVAANIWHVRGPDRDMVVDTGLGVSSLRREIPTLFQRDPVAYVSHW HLDHSGGAHEFDDVRVFETGVPQLLRPPPASLRRHGLQKDLGLPEVGADALLLSQLPAPTYNPDEYRVIP VPNVKGISDTGVLDLGGKTQFRVVHLPGHTHDSSALFNERTGELFSGDVIYDDEGEGLLDTTSDSSVAQY VASFQKLKQMDVQTTYPGHGRTLDRQTLRSMITQYLQKHA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4805 | - | - | 100% (250) | hypothetical protein MAB_4805 |
| M. abscessus ATCC 19977 | MAB_2020c | - | 7e-06 | 24.43% (221) | bifunctional HHDD isomerase/cyclase/dehydrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1948 | - | 1e-05 | 26.75% (228) | hypothetical protein Mb1948 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1913 | - | 1e-05 | 26.75% (228) | hypothetical protein Rv1913 |
| M. leprae Br4923 | MLBr_02303 | - | 5e-07 | 26.82% (220) | putative hydrolase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1057 | - | 3e-06 | 22.67% (225) | fumarylacetoacetate hydrolase family protein, putative |
| M. smegmatis MC2 155 | MSMEG_6278 | - | 2e-06 | 27.83% (230) | metallo-beta-lactamase superfamily protein, putative |
| M. thermoresistible (build 8) | TH_3961 | - | 1e-07 | 28.76% (226) | PUTATIVE putative metallo-beta-lactamase superfamily protein, |
| M. ulcerans Agy99 | MUL_4251 | - | 6e-06 | 27.54% (207) | hypothetical protein MUL_4251 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6278|M.smegmatis_MC2_155 --------------------------------------------------
TH_3961|M.thermoresistible__bu --------------------------------------------------
MLBr_02303|M.leprae_Br4923 --------------------------------------------------
MUL_4251|M.ulcerans_Agy99 --------------------------------------------------
Mb1948|M.bovis_AF2122/97 --------------------------------------------------
Rv1913|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1057|M.avium_104 MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQ
MAB_4805|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6278|M.smegmatis_MC2_155 --------------------------------------------------
TH_3961|M.thermoresistible__bu --------------------------------------------------
MLBr_02303|M.leprae_Br4923 --------------------------------------------------
MUL_4251|M.ulcerans_Agy99 --------------------------------------------------
Mb1948|M.bovis_AF2122/97 --------------------------------------------------
Rv1913|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1057|M.avium_104 RSPAATVPAARARLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRVLADT
MAB_4805|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6278|M.smegmatis_MC2_155 --------------------------------------------------
TH_3961|M.thermoresistible__bu --------------------------------------------------
MLBr_02303|M.leprae_Br4923 --------------------------------------------------
MUL_4251|M.ulcerans_Agy99 --------------------------------------------------
Mb1948|M.bovis_AF2122/97 --------------------------------------------------
Rv1913|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1057|M.avium_104 WYRVPAFYFACPATVLGPYDDAPTAPGSAWQDFELEIAAVIGTGGKDLSV
MAB_4805|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6278|M.smegmatis_MC2_155 --------------------------------------------------
TH_3961|M.thermoresistible__bu --------------------------------------------------
MLBr_02303|M.leprae_Br4923 --------------------------------------------------
MUL_4251|M.ulcerans_Agy99 --------------------------------------------------
Mb1948|M.bovis_AF2122/97 --------------------------------------------------
Rv1913|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1057|M.avium_104 EQAEQAIIGYTIFNDWSARDLQQLDSQLGIGQAKGKDSGVTLGPYLVTPD
MAB_4805|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6278|M.smegmatis_MC2_155 --------------------------------------------------
TH_3961|M.thermoresistible__bu --------------------------------------------------
MLBr_02303|M.leprae_Br4923 --------------------------------------------------
MUL_4251|M.ulcerans_Agy99 --------------------------------------------------
Mb1948|M.bovis_AF2122/97 --------------------------------------------------
Rv1913|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1057|M.avium_104 ELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVISYASRGVTLV
MAB_4805|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6278|M.smegmatis_MC2_155 --------------------------------------------------
TH_3961|M.thermoresistible__bu --------------------------------------------------
MLBr_02303|M.leprae_Br4923 ------------------------------------------------MA
MUL_4251|M.ulcerans_Agy99 ------------------------------------------------MS
Mb1948|M.bovis_AF2122/97 --------------------------------------------------
Rv1913|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1057|M.avium_104 PGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQT
MAB_4805|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6278|M.smegmatis_MC2_155 ---------MPDLLKIADSLYRLRIPGDRAHLLN----------CYLWQE
TH_3961|M.thermoresistible__bu ---------MAEPS--AEPVRAVEVTAELSLLHID------GWQVYVWRD
MLBr_02303|M.leprae_Br4923 EVVKWLAHPAYGRLRAVTDTASVLLADNPGLLTLE------GTNTWVLRG
MUL_4251|M.ulcerans_Agy99 ETAGSLTHPAYGRLRPVTDLASVLVADNPGLLTLE------GTNTWVLRG
Mb1948|M.bovis_AF2122/97 ---------------MHFDWERLTDSVHRCRLPFC------DVTVGLVRG
Rv1913|M.tuberculosis_H37Rv ---------------MHFDWERLTDSVHRCRLPFC------DVTVGLVRG
MAV_1057|M.avium_104 VRASGAPHPLAARPNPDAPPAAPRVNRAAARVPYTRGLHQVGDRVWAWTL
MAB_4805|M.abscessus_ATCC_1997 ------MGSWYSREVVSEHLNLYREIHADSFVAAN---------IWHVRG
:
MSMEG_6278|M.smegmatis_MC2_155 P---------------DGVTLIDTGW-PGEAGLIAEALAMLGLRRLHVKR
TH_3961|M.thermoresistible__bu G---------------DEVTVIDTGQ-PGSG---ARILAHTGT----VTQ
MLBr_02303|M.leprae_Br4923 PG-------------SGELVIVDPG--PGD--EHIVQVATLGR----IAL
MUL_4251|M.ulcerans_Agy99 PR-------------SDELVVVDPG--PADD-EHIARIAALGR----IAL
Mb1948|M.bovis_AF2122/97 R---------------TGILLVDTGTTLGEATAIAADVKQIAG--CQVTH
Rv1913|M.tuberculosis_H37Rv R---------------TGILLVDTGTTLGEATAIAADVKQIAG--CQVTH
MAV_1057|M.avium_104 PDGGYGWSNAGLIAGDGASLLVDTLFDLALTREMLTAMRPITAS-APITD
MAB_4805|M.abscessus_ATCC_1997 P---------------DRDMVVDTGLGVSSLRREIPTLFQRDP------V
::*. . :
MSMEG_6278|M.smegmatis_MC2_155 VVLTHFHEDHTG------AAAEIADWADVEVIAGAADAPFIRGD--EPGP
TH_3961|M.thermoresistible__bu VVLTHGHVDHCG------SAAELQRATGAFVAAGAGDTDAIQAG--AALP
MLBr_02303|M.leprae_Br4923 VLISHRHPDHTD------GIDKLVELTGAPVCA--ADPQFLRGDGVTLTD
MUL_4251|M.ulcerans_Agy99 VLISHRHGDHTD------GIDKLFERTGAPVRA--ADPQFLRGDPVALSD
Mb1948|M.bovis_AF2122/97 VVLTHKHFDHVLG----SSVFDQAEVFCAPEVVEYLRSATDRLREDALSY
Rv1913|M.tuberculosis_H37Rv VVLTHKHFDHVLG----SSVFDQAEVFCAPEVVEYLRSATDRLREDALSY
MAV_1057|M.avium_104 AVITHSNGDHTHGNQLLDPAVRIIAAHGTAEEIAHGMAPEMLAMAQTANL
MAB_4805|M.abscessus_ATCC_1997 AYVSHWHLDHSGG-AHEFDDVRVFETGVPQLLRPPPASLRRHGLQKDLGL
. ::* : ** .
MSMEG_6278|M.smegmatis_MC2_155 LPVLTDAERT---------LRSDLTE--PPVGPPCRVDTTVRDGDVLDFA
TH_3961|M.thermoresistible__bu PPVFEDWERP---------IHEQVAAGLPEAAPAVTVHRDLIDGDVLDFG
MLBr_02303|M.leprae_Br4923 REVIDAGGLT---------ITVLATPGHTADSMSFVLADAVLTADSVLGH
MUL_4251|M.ulcerans_Agy99 GEVIDAGGLK---------ITVLATPGHTADSLSFVLEDAVLTADSVLGR
Mb1948|M.bovis_AF2122/97 GADTAEVDRA---------IAALKPPQHGIYDAAVDLGDRTVTITHPGSG
Rv1913|M.tuberculosis_H37Rv GADTAEVDRA---------IAALKPPQHGIYDAAVDLGDRTVTITHPGSG
MAV_1057|M.avium_104 GPVATRYTRERFGHFDFSNITLRNADETFDRSLAVEVGGRRVDVLNLGPA
MAB_4805|M.abscessus_ATCC_1997 PEVGADALLLS-------QLPAPTYNPDEYRVIPVPNVKGISDTGVLDLG
: .
MSMEG_6278|M.smegmatis_MC2_155 GGARVVGAPG----HTPGSIGLYLPAADAVLTG-----------------
TH_3961|M.thermoresistible__bu GGARVLAVPG----HTDGSIAIHLPEHGVLFTG-----------------
MLBr_02303|M.leprae_Br4923 GTTVIDPDDGSLADYLESLHRLSGLGRRTVLPG-----------------
MUL_4251|M.ulcerans_Agy99 GTTVLDKQDGSLSEYLESLHRLRGLGPRMVLPG-----------------
Mb1948|M.bovis_AF2122/97 HTTADLVVVAPATGHADGPT-VVFTGDLVEESA-----------------
Rv1913|M.tuberculosis_H37Rv HTTADLVVVAPATGHADGPT-VVFTGDLVEESA-----------------
MAV_1057|M.avium_104 HTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAACDAMIALDA
MAB_4805|M.abscessus_ATCC_1997 GKTQFRVVHLP--GHTHDSSALFNERTGELFSG-----------------
: . : ..
MSMEG_6278|M.smegmatis_MC2_155 -------DAVAEFNGHVIVGVFNVDRAAAVASVQR-LAETGAQVAGFGHG
TH_3961|M.thermoresistible__bu -------DTVANV-GTLSLGVFNRDRARTIEAFRR-LAALDVETVCFGHG
MLBr_02303|M.leprae_Br4923 -------HGPDLANLESVASGYLVHRQERLEQVRAALRELGDDATARQVV
MUL_4251|M.ulcerans_Agy99 -------HGPDLADIRIVAQGYLAHRQERLEQVRSALRELGEQASARQIV
Mb1948|M.bovis_AF2122/97 -------DPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFV
Rv1913|M.tuberculosis_H37Rv -------DPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFV
MAV_1057|M.avium_104 PTVVPGHGPVTDPDGIRAVRGYLVHIAEQAEAAYRKGLSWPEAADTIDLG
MAB_4805|M.abscessus_ATCC_1997 -------DVIYDDEGEGLLDTTSDSSVAQYVASFQKLKQMDVQTTYPGHG
.
MSMEG_6278|M.smegmatis_MC2_155 E--------VLLTDAAARIADAADPFA-------------------
TH_3961|M.thermoresistible__bu D--------PIVEGGGHRLREVAAELG-------------------
MLBr_02303|M.leprae_Br4923 E--------HVYVDVDEKFWDAAEWSVQAQLDYLRR----------
MUL_4251|M.ulcerans_Agy99 E--------HVYVDVDEKLWDAAEWSVQVQLNHLHQAGSQS-----
Mb1948|M.bovis_AF2122/97 R--------RQRAWLRTRASRQPRETPATLPCKR------------
Rv1913|M.tuberculosis_H37Rv R--------RQRAWLRTRASRQPRETPATLPCKR------------
MAV_1057|M.avium_104 EYATWLDAERVVVNVYQRYRELDPHTPQLEVMALLVMQAEWLAKRS
MAB_4805|M.abscessus_ATCC_1997 R-----------TLDRQTLRSMITQYLQKHA---------------