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PDLLKIADSLYRLRIPGDRAHLLNCYLWQEPDGVTLIDTGWPGEAGLIAEALAMLGLRRLHVKRVVLTHF HEDHTGAAAEIADWADVEVIAGAADAPFIRGDEPGPLPVLTDAERTLRSDLTEPPVGPPCRVDTTVRDGD VLDFAGGARVVGAPGHTPGSIGLYLPAADAVLTGDAVAEFNGHVIVGVFNVDRAAAVASVQRLAETGAQV AGFGHGEVLLTDAAARIADAADPFA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6278 | - | - | 100% (236) | metallo-beta-lactamase superfamily protein, putative |
| M. smegmatis MC2 155 | MSMEG_0775 | - | 2e-12 | 29.03% (217) | metallo-beta-lactamase superfamily protein |
| M. smegmatis MC2 155 | MSMEG_6190 | - | 3e-06 | 27.60% (192) | metallo-beta-lactamase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0414c | - | 7e-12 | 25.96% (235) | beta lactamase like protein |
| M. gilvum PYR-GCK | Mflv_0212 | - | 8e-13 | 28.26% (230) | beta-lactamase domain-containing protein |
| M. tuberculosis H37Rv | Rv0406c | - | 7e-12 | 25.96% (235) | beta lactamase like protein |
| M. leprae Br4923 | MLBr_00270 | - | 6e-11 | 25.85% (236) | hypothetical protein MLBr_00270 |
| M. abscessus ATCC 19977 | MAB_1114 | - | 2e-90 | 67.95% (234) | metallo-beta-lactamase superfamily |
| M. marinum M | MMAR_0708 | - | 9e-10 | 25.00% (236) | beta lactamase-like protein |
| M. avium 104 | MAV_4762 | - | 1e-11 | 26.40% (250) | metallo-beta-lactamase superfamily protein |
| M. thermoresistible (build 8) | TH_3961 | - | 7e-36 | 41.35% (208) | PUTATIVE putative metallo-beta-lactamase superfamily protein, |
| M. ulcerans Agy99 | MUL_2815 | - | 6e-10 | 25.00% (236) | beta lactamase-like protein |
| M. vanbaalenii PYR-1 | Mvan_0697 | - | 6e-15 | 32.35% (238) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00270|M.leprae_Br4923 ------------------MAAATLFQVTDSVHFARGDAVNWALVADDTGV
MAV_4762|M.avium_104 --------------------MAELVQVTDAVHLARGDAVNWTLVADDTGV
Mb0414c|M.bovis_AF2122/97 MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGV
Rv0406c|M.tuberculosis_H37Rv MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGV
MMAR_0708|M.marinum_M MPHQR----------------TELVQVTDKVHLAQGPAVNWVLVTDETGV
MUL_2815|M.ulcerans_Agy99 MPHQR----------------TELVQVTDKVHLAQGPAVNWVLVTDETGV
Mflv_0212|M.gilvum_PYR-GCK -------------------MAPVVTAVTDRVHFVRTELVNWTLVRDDDGV
Mvan_0697|M.vanbaalenii_PYR-1 -------------------MALALTAITDRVHFAQTDLVNWTLVAEDGGV
MSMEG_6278|M.smegmatis_MC2_155 ---------------MPDLLKIADSLYRLRIPGDRAHLLNCYLWQEPDGV
MAB_1114|M.abscessus_ATCC_1997 -------------MSSPDLQQLAPSLFRLRIPGGRAHLLNCYLWLAPDGV
TH_3961|M.thermoresistible__bu -------------MAEPSAEPVRAVEVTAELSLLHIDGWQVYVWRDGDEV
: : : : *
MLBr_00270|M.leprae_Br4923 MLIDTGYPGDRDDVVASLRQLGYEAGDVRAILLTHAHIDHMGSAIWFASK
MAV_4762|M.avium_104 MLVDAGYPGDREDVLGSLAELGYGPGDVRAIVLTHAHIDHLGTAIWLASE
Mb0414c|M.bovis_AF2122/97 LLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFARE
Rv0406c|M.tuberculosis_H37Rv LLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFARE
MMAR_0708|M.marinum_M MLIDAGYPGDRNNVLTSLRTLGYGPGDVRAILLTHAHIDHLGTAIWFAAQ
MUL_2815|M.ulcerans_Agy99 MLIDAGYPGDRNNVLTSLRTLGYGPGDVRAILLTHAHIDHLGTAIWFAAQ
Mflv_0212|M.gilvum_PYR-GCK ILIDAGFPGHRDEVLTSLHGLGFGVGDVRAILLTHAHIDHFGTAIWFAAT
Mvan_0697|M.vanbaalenii_PYR-1 LLIDAGYPGHREEVLESLGRLGFGATDVRAILLTHAHIDHFGSAMWFARE
MSMEG_6278|M.smegmatis_MC2_155 TLIDTGWPGEAGLIAEALAMLGLRRLHVKRVVLTHFHEDHTGAAAEIADW
MAB_1114|M.abscessus_ATCC_1997 TLIDTGWPDSAELIEQALHQLGRGRTDIVRIVLTHFHEDHVGAAAEIAAW
TH_3961|M.thermoresistible__bu TVIDTGQPGSG---ARILAHTG----TVTQVVLTHGHVDHCGSAAELQRA
::*:* *. * * : ::*** * ** *:* :
MLBr_00270|M.leprae_Br4923 HRTPVYCHADEVGHTKREYLEQVSLLNIAMRVWQPRWAIWSGHVLRSGGL
MAV_4762|M.avium_104 HGIPVYCHADEVGHAKREYLEQVSIVDVALRIWRPRWAKWTAHVVRSGGL
Mb0414c|M.bovis_AF2122/97 HSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL
Rv0406c|M.tuberculosis_H37Rv HSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL
MMAR_0708|M.marinum_M HGTPVYCDANEVGHAKREYHESASPLDVVLRSWRPRTALWGIHLVFRGGL
MUL_2815|M.ulcerans_Agy99 HGTPVYCDANEVGHAKREYHESASPLDVVLRSWRPRTALWGIHLVFRGGL
Mflv_0212|M.gilvum_PYR-GCK HGTPVYCHADEVAHSRRDHLEQASPIDIAKHAWQPTWLKWSVSIIGKGAL
Mvan_0697|M.vanbaalenii_PYR-1 HGTPVYCHADEVGHAKREYLEQASPLAVAAHAWQPRWLKWSLTLIRKGGL
MSMEG_6278|M.smegmatis_MC2_155 ADVEVIAGAADAPFIRGDEPGPLPVLTDAERTLRSDLTE---------PP
MAB_1114|M.abscessus_ATCC_1997 SRAEVIAGEPDSPFITGERGGPVPVLTAGEQALHPGFTE---------PP
TH_3961|M.thermoresistible__bu TGAFVAAGAGDTDAIQAGAALPPPVFEDWERPIHEQVAAG-------LPE
* . : . . : :
MLBr_00270|M.leprae_Br4923 IRGGIPTAQPLTAETAAGLPGHPMAIFTPGHTGGHCSYVVDGVLISGDAL
MAV_4762|M.avium_104 IRDGIPTAQPLTAEVAAGLPGRPTPVFSPGHTNGHCSYLIDGVLVSGDAL
Mb0414c|M.bovis_AF2122/97 TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL
Rv0406c|M.tuberculosis_H37Rv TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL
MMAR_0708|M.marinum_M RRAGVPSTQALSAEVAAALPGHPIPIPTPGHTSGHCSYLVDGVLASGDAL
MUL_2815|M.ulcerans_Agy99 RRAGVPSTQALSAEVAAALPGHPIPIPTPGHTSGHCSYLVDGVLASGDAL
Mflv_0212|M.gilvum_PYR-GCK TRAGIASTAPLTDHIAAALPGSPVCIPTPGHTGGHCSYVVDGVLVSGDAL
Mvan_0697|M.vanbaalenii_PYR-1 DRTGIPTTAALSEDIAAGLPGAPVCVPTPGHTGGHCSYVVDGVLVSGDAL
MSMEG_6278|M.smegmatis_MC2_155 VGPPCRVDTTVRDGDVLDFAGGARVVGAPGHTPGSIGLYLP----AADAV
MAB_1114|M.abscessus_ATCC_1997 HGPVCRVDRAVKDGEVLDFAGGAHVIAVPGHTPGSIALYLP----AADAV
TH_3961|M.thermoresistible__bu AAPAVTVHRDLIDGDVLDFGGGARVLAVPGHTDGSIAIHLP----EHGVL
: . : * . : **** * . : ..:
MLBr_00270|M.leprae_Br4923 ITGHPLLRHRGPQLLTAVFSHSQKQCLRSLDALGLLETRILAPGHGELWH
MAV_4762|M.avium_104 ITGHPLLRHRGPQLLPAIFSYSQRDCIRTLSALALLDTEVLLPGHGDVWR
Mb0414c|M.bovis_AF2122/97 ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWH
Rv0406c|M.tuberculosis_H37Rv ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWH
MMAR_0708|M.marinum_M ITGHPMLRHRGPQLLPAVFSKVQERCIRSLSTLAQVEADTLAPGHGSLWR
MUL_2815|M.ulcerans_Agy99 ITGHPMLRHRGPQLLPAVFSKVQERCIRSLSTLAQVEADTLAPGHGSLWR
Mflv_0212|M.gilvum_PYR-GCK ITGHPVASRRGPQLLPSVFNHDEDACRRSLTTLGALDTEVILPGHGPLWR
Mvan_0697|M.vanbaalenii_PYR-1 ITGHPVSRRRGPQLLPSVFNHDEVACLRSLEALGMLDTEVMLPGHGPVWR
MSMEG_6278|M.smegmatis_MC2_155 LTGDAVAEFNGHVIVG-VFNVDRAAAVASVQRLAETGAQVAGFGHGEVLL
MAB_1114|M.abscessus_ATCC_1997 LTGDAVAEFNGQVILG-VFNSDRQVAARSLSRLAATGAEIGGFGHGEAIL
TH_3961|M.thermoresistible__bu FTGDTVANV-GTLSLG-VFNRDRARTIEAFRRLAALDVETVCFGHGDPIV
:**..: * : :*. . :. *. . ***
MLBr_00270|M.leprae_Br4923 GPIREATEAALKQAGALTR---
MAV_4762|M.avium_104 GPIKEATDAALALATGR-----
Mb0414c|M.bovis_AF2122/97 GPIRKATDEALERAQKSNHVFR
Rv0406c|M.tuberculosis_H37Rv GPIRKATDEALERAQKSNHVFR
MMAR_0708|M.marinum_M GPIRLATEEARARAQR------
MUL_2815|M.ulcerans_Agy99 GPIRLATEEARARAQR------
Mflv_0212|M.gilvum_PYR-GCK GPVRDAAAQAAQASVR------
Mvan_0697|M.vanbaalenii_PYR-1 GPVRDAVAQATTAEP-------
MSMEG_6278|M.smegmatis_MC2_155 TDAAARIADAADPFA-------
MAB_1114|M.abscessus_ATCC_1997 EKASARIATAIDAFGE------
TH_3961|M.thermoresistible__bu EGGGHRLREVAAELG-------
.