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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3961 | - | - | 100% (233) | putative metallo-beta-lactamase superfamily protein, putative |
| M. thermoresistible (build 8) | TH_2128 | - | 9e-11 | 29.02% (224) | POSSIBLE HYDROLASE |
| M. thermoresistible (build 8) | TH_1503 | - | 4e-10 | 30.77% (221) | CONSERVED HYPOTHETICAL PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3701c | - | 1e-11 | 29.26% (229) | putative hydrolase |
| M. gilvum PYR-GCK | Mflv_1370 | - | 1e-11 | 28.51% (221) | beta-lactamase domain-containing protein |
| M. tuberculosis H37Rv | Rv3677c | - | 1e-11 | 29.26% (229) | hydrolase |
| M. leprae Br4923 | MLBr_00493 | - | 4e-11 | 32.34% (201) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_1114 | - | 7e-34 | 42.65% (204) | metallo-beta-lactamase superfamily |
| M. marinum M | MMAR_2126 | - | 1e-10 | 31.22% (205) | Zn-dependent glyoxylase |
| M. avium 104 | MAV_3461 | - | 2e-12 | 34.47% (206) | metallo-beta-lactamase family protein |
| M. smegmatis MC2 155 | MSMEG_6278 | - | 1e-35 | 41.35% (208) | metallo-beta-lactamase superfamily protein, putative |
| M. ulcerans Agy99 | MUL_1731 | - | 1e-10 | 31.22% (205) | Zn-dependent glyoxylase |
| M. vanbaalenii PYR-1 | Mvan_5436 | - | 4e-10 | 26.79% (224) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2126|M.marinum_M ---------------MLITGFPAGVLQCNCYVLAERPGTDAIIVDPGQRA
MUL_1731|M.ulcerans_Agy99 ---------------MLITGFPAGVLQCNCYALAERPGTDAIIVDPGQRA
MAV_3461|M.avium_104 ---------------MLITGFPAGMLACNCYVLAQRPGTDAVIVDPGQRA
MLBr_00493|M.leprae_Br4923 ---------------MLITGFPAGMLQCNCYVLADRAGTDAVIVDPGQRA
Mb3701c|M.bovis_AF2122/97 ---------------MSKTAESLTHPAYGQLRAVTDTASVLLADNPGLLT
Rv3677c|M.tuberculosis_H37Rv ---------------MSKTAESLTHPAYGQLRAVTDTASVLLADNPGLLT
Mflv_1370|M.gilvum_PYR-GCK ----------------------MEHPAYNVLRPVTDTASVLLCENPGLMT
Mvan_5436|M.vanbaalenii_PYR-1 ----------------------MEHPAYGLLRPVTDTASVLLCENPGLMT
MAB_1114|M.abscessus_ATCC_1997 MSSPDLQQLAPSLFRLRIPGGRAHLLNCYLWLAPDGVTLIDTGWPDSAEL
MSMEG_6278|M.smegmatis_MC2_155 --MPDLLKIADSLYRLRIPGDRAHLLNCYLWQEPDGVTLIDTGWPGEAGL
TH_3961|M.thermoresistible__bu MAEPSAEPVRAVEVTAELSLLHIDGWQVYVWRDGDEVTVIDTGQPGSG--
MMAR_2126|M.marinum_M MGQLRRILDKNRLTPAAVLITHGHIDHMWSAQKVSDTFGCPTYIHPEDRF
MUL_1731|M.ulcerans_Agy99 MGQLRRILDKNRLTPAAVLITHGHIDHMWSAQKVSDTFGCPTYIHPEDRF
MAV_3461|M.avium_104 MGPLRRILDRHRLTPAAVLLTHGHIDHIWSAQKVSDTYGCPTYIHPEDRF
MLBr_00493|M.leprae_Br4923 MGPLRRILDENRLTPSAVLLTHGHIDHMWSAQKVSDTYGCPTYIHPEDRF
Mb3701c|M.bovis_AF2122/97 LDGTNTWVLRGPLSDELVVVDPGPDD-DEHLARVAALGRIALVLISHRHG
Rv3677c|M.tuberculosis_H37Rv LDGTNTWVLRGPLSDELVVVDPGPDD-DEHLARVAALGRIALVLISHRHG
Mflv_1370|M.gilvum_PYR-GCK LDGTNTWVLRGPGSDEMVVVDPGPDDKDEHIERLAALGRISLVLISHRHG
Mvan_5436|M.vanbaalenii_PYR-1 LDGTNTWVLRGPGSDEMVVVDPGPDDRDEHIERLAALGPIPLVLISHRHA
MAB_1114|M.abscessus_ATCC_1997 IEQALHQLGRGRTDIVRIVLTHFHEDHVGAAAEIAAWSRAEVIAGEPDSP
MSMEG_6278|M.smegmatis_MC2_155 IAEALAMLGLRRLHVKRVVLTHFHEDHTGAAAEIADWADVEVIAGAADAP
TH_3961|M.thermoresistible__bu -ARILAHTG----TVTQVVLTHGHVDHCGSAAELQRATGAFVAAGAGDTD
::: * .:
MMAR_2126|M.marinum_M MLKDPIYGLGPRVAQLFAGAFFREPK---------QVVELDRDGDKIDLG
MUL_1731|M.ulcerans_Agy99 MLKDPIYGLGPRVAQLFAGAFFREPK---------QVVELDRDGDKIDLG
MAV_3461|M.avium_104 MLKDPIYGLGPRLAQLAAGAFFREPR---------QVVELDRDGDKLDLG
MLBr_00493|M.leprae_Br4923 MLTDPLFGFGPRVAQVVTGAFFREPK---------QVVELDRDGDKLDLG
Mb3701c|M.bovis_AF2122/97 DHTSGIDKLVALTGAPVRAADPQFLR---------RDGETLTDGEVIDVA
Rv3677c|M.tuberculosis_H37Rv DHTSGIDKLVALTGAPVRAADPQFLR---------RDGETLTDGEVIDVA
Mflv_1370|M.gilvum_PYR-GCK DHTGGIDRLVDMTGAVVRSVGSGFQR---------GLGGTLTDGEVIDAA
Mvan_5436|M.vanbaalenii_PYR-1 DHTGGIDRIVDLTGAVVRSVGSGFQR---------GLGGTLTDGEVIDAA
MAB_1114|M.abscessus_ATCC_1997 FITGERGGPVPVLTAGEQALHPGFTE--PPHGPVCRVDRAVKDGEVLDFA
MSMEG_6278|M.smegmatis_MC2_155 FIRGDEPGPLPVLTDAERTLRSDLTE--PPVGPPCRVDTTVRDGDVLDFA
TH_3961|M.thermoresistible__bu AIQAGAALPPPVFEDWERPIHEQVAAGLPEAAPAVTVHRDLIDGDVLDFG
**: :* .
MMAR_2126|M.marinum_M NICVNVDHTPGHTRGSVCFRVPQAAKDDRDVVFTGDTLFER---------
MUL_1731|M.ulcerans_Agy99 NICVNVDHTPGHTRGSVCFRVPQAAKDDRDVVFTGDTLFER---------
MAV_3461|M.avium_104 SVTVNVDHTPGHTRGSMCFRVS----SDKQVVFTGDTLFER---------
MLBr_00493|M.leprae_Br4923 SVTVNVDHTPGHTRGSVCFWVA----ADTDVVLTGDTLFER---------
Mb3701c|M.bovis_AF2122/97 GLTITVLATPGHTADSLSFVLDDAVLTADTVLGCGTTVIDKEDGSLADYL
Rv3677c|M.tuberculosis_H37Rv GLTITVLATPGHTADSLSFVLDDAVLTADTVLGCGTTVIDKEDGSLADYL
Mflv_1370|M.gilvum_PYR-GCK GLAITVMATPGHTADSVSFLVDDAVLTADTVLGRGTTVIDSEDGDLGDYL
Mvan_5436|M.vanbaalenii_PYR-1 GLKITVMATPGHTADSMSFLVGDAVLTADTILGRGTTVIDSEDGDLGDYL
MAB_1114|M.abscessus_ATCC_1997 G-GAHVIAVPGHTPGSIALYLP-----AADAVLTGDAVAEFN--------
MSMEG_6278|M.smegmatis_MC2_155 G-GARVVGAPGHTPGSIGLYLP-----AADAVLTGDAVAEFN--------
TH_3961|M.thermoresistible__bu G-GARVLAVPGHTDGSIAIHLP-----EHGVLFTGDTVANV---------
. * .**** .*: : : : * :: :
MMAR_2126|M.marinum_M -------SIGRSDLFGGSG------------------------RDLLRSI
MUL_1731|M.ulcerans_Agy99 -------SIGRSDLFGGSG------------------------RDLLRSI
MAV_3461|M.avium_104 -------SVGRTDLFGGSG------------------------RDLLTSI
MLBr_00493|M.leprae_Br4923 -------TIGRTDLFGGSG------------------------RDLYRSI
Mb3701c|M.bovis_AF2122/97 ESLHRLRGLGRRTVLPGHGPDLLDLEAIASGYLLHRHERLEQIRAALRDL
Rv3677c|M.tuberculosis_H37Rv ESLHRLRGLGRRTVLPGHGPDLLDLEAIASGYLLHRHERLEQIRAALRDL
Mflv_1370|M.gilvum_PYR-GCK ESLRRLRGLGHLTVLPGHGPELDDMAAVSEFYLAHREERLAQVRGALGAL
Mvan_5436|M.vanbaalenii_PYR-1 ESLRRLHGLGHRRVLPGHGPELDDVVVVSQDYLTHREERLEQVRAALREL
MAB_1114|M.abscessus_ATCC_1997 -------GQVILGVFNSDR--------------------------QVAAR
MSMEG_6278|M.smegmatis_MC2_155 -------GHVIVGVFNVDR--------------------------AAAVA
TH_3961|M.thermoresistible__bu -------GTLSLGVFNRDR--------------------------ARTIE
::
MMAR_2126|M.marinum_M VDKLLVLDDKTVVLPGHGNSTSIGAERRFNPFLEGLST-
MUL_1731|M.ulcerans_Agy99 VDKLLVLDDKTVVLPGHGNSTSIGAERRFNPFLEGLST-
MAV_3461|M.avium_104 VDKLLVLDDDTVVLPGHGNATTIGAERRLNPFLEGL---
MLBr_00493|M.leprae_Br4923 VEKLLVLDDKTVVLPGHGNSTTIGAERRFNPFLEGL---
Mb3701c|M.bovis_AF2122/97 GDDATVREVVEHVYLDVDEKLWNAAEWSVQAQLDYLRTR
Rv3677c|M.tuberculosis_H37Rv GDDATVREVVEHVYLDVDEKLWNAAEWSVQAQLDYLRTR
Mflv_1370|M.gilvum_PYR-GCK GEDATARQVVEHVYTDVDEKLWDAAEWSVQAQLNYLRR-
Mvan_5436|M.vanbaalenii_PYR-1 GEDATARQVVEHVYTDVDEKLWDAAESSVQAQLDHLRR-
MAB_1114|M.abscessus_ATCC_1997 SLSRLAATGAEIGGFGHGEAILEKASARIATAIDAFGE-
MSMEG_6278|M.smegmatis_MC2_155 SVQRLAETGAQVAGFGHGEVLLTDAAARIADAADPFA--
TH_3961|M.thermoresistible__bu AFRRLAALDVETVCFGHGDPIVEGGGHRLREVAAELG--
. . .: . . :