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VANVDRRQMLLLSGLGATAAVLPVPRAAAVPNQTAASYVFADEFDGPAGSAPSAAKWTIAKARETIQDPT YWEQPGRIGQYRNDRRNVFLDGKSNLVIRAAKDGDTYYSAKLASVWEGGAGHTWEARIKFNCLTAGAWPA FWLGNTGEGELDIIEWYGNGSWPSATTVHAKSNGGEWKTHNIAVDNGWHRWRTQWDAEGARFWLDYTDGA QPYFEVAASSLPDWPFDQPGYTMFVVLNLAVAGSGGGDPSGGTYPADMLVDWVRVW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5345 | - | - | 100% (266) | glycosyl hydrolases family protein 16 |
| M. smegmatis MC2 155 | MSMEG_0645 | - | 2e-82 | 51.44% (278) | putative beta-1,3-glucanase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0323 | - | 7e-90 | 51.90% (289) | beta-1,3-glucanase precursor |
| M. gilvum PYR-GCK | Mflv_0298 | - | 1e-82 | 49.30% (284) | glycoside hydrolase family protein |
| M. tuberculosis H37Rv | Rv0315 | - | 4e-89 | 51.56% (289) | beta-1,3-glucanase precursor |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4740 | - | 1e-117 | 67.52% (274) | beta-1,3-glucanase |
| M. marinum M | MMAR_2902 | - | 1e-121 | 69.34% (274) | beta-1,3-glucanase precursor |
| M. avium 104 | MAV_2761 | - | 1e-125 | 71.48% (270) | glycosyl hydrolases family protein 16 |
| M. thermoresistible (build 8) | TH_0196 | - | 1e-85 | 51.76% (284) | POSSIBLE BETA-1,3-GLUCANASE PRECURSOR |
| M. ulcerans Agy99 | MUL_4744 | - | 6e-89 | 51.57% (287) | beta-1,3-glucanase precursor |
| M. vanbaalenii PYR-1 | Mvan_0446 | - | 2e-85 | 51.22% (287) | glycoside hydrolase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0323|M.bovis_AF2122/97 MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPA
Rv0315|M.tuberculosis_H37Rv MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPA
MUL_4744|M.ulcerans_Agy99 MLMQEIDRRRIIMMAGFGALAAAIPAPTAGAAP---IPPAAPEPAPAAPA
MMAR_2902|M.marinum_M --MPEMDRRRMMLMTGFGVLGAALPVPAASADSSRRDMPLAPAPNGQSGP
MAV_2761|M.avium_104 --MPEIDRRRMIVTTGIGVLAAALPNPRAGASP----APPPAAPSGQSGT
MSMEG_5345|M.smegmatis_MC2_155 --MANVDRRQMLLLSGLGATAAVLPVPRA-----------AAVPNQTAAS
MAB_4740|M.abscessus_ATCC_1997 -----MDRRRMMAFSGLGMLAAAASMPQAWAQPSPLGPPNRPPAAPPTGK
TH_0196|M.thermoresistible__bu --MPMMNRRQAMMMLGFGAVAAALPLPQAGAQPVL-DAPAPGPDTP--EA
Mvan_0446|M.vanbaalenii_PYR-1 -----MDRRRAMLTLGFGMAAAALPFPKAGAQPVIGDAPPPGPSGPGLPE
Mflv_0298|M.gilvum_PYR-GCK --MPEMDRRKAMLMMGLGAAVVASPLGSAHAQ------PPAVPSEPLPAG
::**: : *:* .. . *
Mb0323|M.bovis_AF2122/97 AATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQY
Rv0315|M.tuberculosis_H37Rv AATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQY
MUL_4744|M.ulcerans_Agy99 AGAGPIFLWHDEFDGPAGSAPDPSKWQVSNHRTPIRNPVGFDRPEFWGQY
MMAR_2902|M.marinum_M ------YLFHDEFDGPAGSAPDSSKWTVARAREEMKDPTYWERPENVGQY
MAV_2761|M.avium_104 ------YLFQDEFDGPAGSAPDASKWAVAKARETIKDPTYWERPENIGQY
MSMEG_5345|M.smegmatis_MC2_155 ------YVFADEFDGPAGSAPSAAKWTIAKARETIQDPTYWEQPGRIGQY
MAB_4740|M.abscessus_ATCC_1997 ------YVFVDEFDGPAGSAPDGSKWAISKARETMKDPTFWELPENVGQY
TH_0196|M.thermoresistible__bu ASGP-GLLFADEFDGPAGSPPDPAKWFIVPERETIRNPVEWDKPYNMGRY
Mvan_0446|M.vanbaalenii_PYR-1 AAVP-GLLFADEFNGPAGSPPNPAAWFIVPARETIRNPHEWDKPFNMGRY
Mflv_0298|M.gilvum_PYR-GCK DAGP-LMLFQDEFDGPAGAPPDPARWFIVPARETIRNPVEWDKPFNMGRY
:: ***:****: *. : * : * :::* :: * *:*
Mb0323|M.bovis_AF2122/97 RDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTWEA
Rv0315|M.tuberculosis_H37Rv RDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTWEA
MUL_4744|M.ulcerans_Agy99 RDNRQNVFLDGNSNLVLRATR-SGN----DYFGGLVHGLWRGGIGTTWEA
MMAR_2902|M.marinum_M RDDRQNVFLDGKSNLVIRAAK-DGG----TYYAGKIQSPWRGGIGHTWEA
MAV_2761|M.avium_104 RDDRRNVFLDGKSNLVLRAAK-DGP----TYYSGKVQSLWRGGVGHTWEA
MSMEG_5345|M.smegmatis_MC2_155 RNDRRNVFLDGKSNLVIRAAK-DGD----TYYSAKLASVWEGGAGHTWEA
MAB_4740|M.abscessus_ATCC_1997 RDDRKNVFLDGNSNLVIKAAK-EGN----TYYGGKIYSTTELGIGYTWEA
TH_0196|M.thermoresistible__bu VTDQEHVFHDGNGNLVIRATRGPGANIREKYASAKIVGLWRGGVGTTWEA
Mvan_0446|M.vanbaalenii_PYR-1 VTDQEHVFQDGNGNLVIRATRGEGANIQEKYASAKIIGNWRGGVGTTWEA
Mflv_0298|M.gilvum_PYR-GCK VTDQEHVFQDGNGNLVIRATRGEGTTIQEKYASAKIMGTWRGGIGTTWEA
.:.:** **:.***::*:: * * .. : . . * * ****
Mb0323|M.bovis_AF2122/97 RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPD
Rv0315|M.tuberculosis_H37Rv RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPD
MUL_4744|M.ulcerans_Agy99 RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGSWPSGTTVHANPD
MMAR_2902|M.marinum_M RIKFDCLTAGCWPAWWLGNQD---RGEIDIIEWYGNGSWPSATTVHAKAN
MAV_2761|M.avium_104 RIKLDCLTAGAWPAYWLGNDD---QGEIDVMEWYGNGNWPSATTVHAKAN
MSMEG_5345|M.smegmatis_MC2_155 RIKFNCLTAGAWPAFWLGNTG---EGELDIIEWYGNGSWPSATTVHAKSN
MAB_4740|M.abscessus_ATCC_1997 RIKFNCLTPGAWPAFWLGSDQ---DGEIDIVEWYGNGSWPSATTVHAKAN
TH_0196|M.thermoresistible__bu RVKLNCLTDGAWPAFWLLNDDPVRGAEIDIFEWYGNRDWPSGATVHAKLD
Mvan_0446|M.vanbaalenii_PYR-1 RIKLNCLTDGAWPAFWLINDNPVRGGEVDLVEWYGNRDWPSGTTVHAKLD
Mflv_0298|M.gilvum_PYR-GCK RVKLDCLTDGAWPAFWLVNENPVRGGEVDLVEWYGNNDWPSGTTVHARLD
*:*::**: * ***:** . .*:*:.***** ***.:****. :
Mb0323|M.bovis_AF2122/97 GTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIED
Rv0315|M.tuberculosis_H37Rv GTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIED
MUL_4744|M.ulcerans_Agy99 GTAFETFPIGVDDNWYNWRVTWNVTGMYFWLDYADGMQPYFSVPATGIED
MMAR_2902|M.marinum_M GSEWKTRNVALDSGWHTWRCQWDETGMRFWQDYAEGAQPYFTVAAH----
MAV_2761|M.avium_104 GGEWKTHNIAVDSAWHTWRCQWDEAGIRFWKDYVDGAQPYFDVPAS----
MSMEG_5345|M.smegmatis_MC2_155 GGEWKTHNIAVDNGWHRWRTQWDAEGARFWLDYTDGAQPYFEVAAS----
MAB_4740|M.abscessus_ATCC_1997 GSEWKTHNISLDSGWHTWRTQWDDKGIRFWKDYTDGATPYFEVPAN----
TH_0196|M.thermoresistible__bu GTMFQTQNYPVDSAWHTWRMTWLPSGMYFWQDYEPGKEPFFTVLAN----
Mvan_0446|M.vanbaalenii_PYR-1 GTMFQTHKHPIDSAWHTWRMTWLPTGMYFWKDYQPGMEPFFTVASN----
Mflv_0298|M.gilvum_PYR-GCK GTAFATNRHPVDNAWHTWRMTWQPTGLYFWKDYQPGMEPFFTVPAN----
* : * :*. *: ** * * ** ** * *:* * :
Mb0323|M.bovis_AF2122/97 LNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF
Rv0315|M.tuberculosis_H37Rv LNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF
MUL_4744|M.ulcerans_Agy99 LNEPIREWPFNDPDYTVFPVLNLAVGGSGGGDPAAGTYPQEMLVDWVRVF
MMAR_2902|M.marinum_M ---SLPDWPFNDPGYTVFPVLNLAVAGSGGGDPRPGSYPAQMLVDWVRVW
MAV_2761|M.avium_104 ---SLPDWPFNGPGYTVFPVFNLAVAGSGGGDPGPGSYPADMLIDWIRVW
MSMEG_5345|M.smegmatis_MC2_155 ---SLPDWPFDQPGYTMFVVLNLAVAGSGGGDPSGGTYPADMLVDWVRVW
MAB_4740|M.abscessus_ATCC_1997 ---SLADWPFNNPGHKAFAVLNLAVAGSGGGDPRGGTYPAEMLVDWIRVW
TH_0196|M.thermoresistible__bu ---SLPEWPFNDPGYTMVPVFNIAVGGSGGREPAGGSYPADMIIDWIRVF
Mvan_0446|M.vanbaalenii_PYR-1 ---SLPDWPFNDPGYTMAPVFNIAVGGSGGREPAGGTYPAEMLVDWIRVF
Mflv_0298|M.gilvum_PYR-GCK ---SIPDWPFNDPGFTMVPVFNIAVGGSGGREPAAGTYPAEMRVDWIRVF
.: :***: *... *:*:**.**** :* *:** :* :**:**:
Mb0323|M.bovis_AF2122/97 --
Rv0315|M.tuberculosis_H37Rv --
MUL_4744|M.ulcerans_Agy99 --
MMAR_2902|M.marinum_M --
MAV_2761|M.avium_104 --
MSMEG_5345|M.smegmatis_MC2_155 --
MAB_4740|M.abscessus_ATCC_1997 --
TH_0196|M.thermoresistible__bu --
Mvan_0446|M.vanbaalenii_PYR-1 --
Mflv_0298|M.gilvum_PYR-GCK AS