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GFGMAAAALPLPKAQADRVHPPAAPPDAQSSGFVFRDEFDGPAGSAPDGSKWVAAKFRERIKNPVFWDRP ENMGEYRDSRTNIFLDGNSNLVIRATKEGNKYFSGKLHGTFRGGMGHTFEARIKFNCLTDGCWPAWWLLN DNPERGGEIDMAEWYGNRDWPSGTTVHARLDGTSFETLPVPIDSNWHTWRCTWTEAGLYFWMDYHDGMEP YLTVDANSLDDWPFNDPGYTLQPMLNLAVAGSGGGDPAGGSYPAEMLVDYVRVW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1840c | - | - | 100% (265) | putative beta-glucanase |
| M. abscessus ATCC 19977 | MAB_4740 | - | 1e-98 | 60.67% (267) | beta-1,3-glucanase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0323 | - | 1e-107 | 63.08% (279) | beta-1,3-glucanase precursor |
| M. gilvum PYR-GCK | Mflv_0298 | - | 2e-97 | 58.55% (275) | glycoside hydrolase family protein |
| M. tuberculosis H37Rv | Rv0315 | - | 1e-106 | 62.72% (279) | beta-1,3-glucanase precursor |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2902 | - | 1e-106 | 63.30% (267) | beta-1,3-glucanase precursor |
| M. avium 104 | MAV_2761 | - | 1e-103 | 62.50% (264) | glycosyl hydrolases family protein 16 |
| M. smegmatis MC2 155 | MSMEG_0645 | - | 1e-101 | 61.68% (274) | putative beta-1,3-glucanase |
| M. thermoresistible (build 8) | TH_0196 | - | 1e-100 | 60.36% (275) | POSSIBLE BETA-1,3-GLUCANASE PRECURSOR |
| M. ulcerans Agy99 | MUL_4744 | - | 1e-104 | 61.87% (278) | beta-1,3-glucanase precursor |
| M. vanbaalenii PYR-1 | Mvan_0446 | - | 1e-102 | 61.87% (278) | glycoside hydrolase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0196|M.thermoresistible__bu --MPMMNRRQAMMMLGFGAVAAALPLPQAGAQPVL----DAPAPGPDTP-
Mvan_0446|M.vanbaalenii_PYR-1 -----MDRRRAMLTLGFGMAAAALPFPKAGAQPVIG---DAPPPGPSGPG
Mflv_0298|M.gilvum_PYR-GCK --MPEMDRRKAMLMMGLGAAVVASPLGSAHAQPPA-----VPSEP--LP-
MSMEG_0645|M.smegmatis_MC2_155 ----------MMFMMGLGVAAAALPVGTAGADPLIG---DNPPGP--GP-
Mb0323|M.bovis_AF2122/97 MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAP-
Rv0315|M.tuberculosis_H37Rv MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAP-
MUL_4744|M.ulcerans_Agy99 MLMQEIDRRRIIMMAGFGALAAAIPAPTAGAAP---IPPAAPEPAPAAP-
MMAR_2902|M.marinum_M --MPEMDRRRMMLMTGFGVLGAALPVPAASADSS-----RRDMPLAPAP-
MAV_2761|M.avium_104 --MPEIDRRRMIVTTGIGVLAAALPNPRAGASP---------APPPAAP-
MAB_1840c|M.abscessus_ATCC_199 --------------MGFGMAAAALPLPKAQADR--------VHPPAAPP-
*:* .* * * * *
TH_0196|M.thermoresistible__bu -EAASGPGLLFADEFDGPAGSPPDPAKWFIVPERETIRNPVEWDKPYNMG
Mvan_0446|M.vanbaalenii_PYR-1 LPEAAVPGLLFADEFNGPAGSPPNPAAWFIVPARETIRNPHEWDKPFNMG
Mflv_0298|M.gilvum_PYR-GCK -AGDAGPLMLFQDEFDGPAGAPPDPARWFIVPARETIRNPVEWDKPFNMG
MSMEG_0645|M.smegmatis_MC2_155 -AAAAEPTFLFQDEFNGPAGSPPDPAWWYLVPARETIKNPVEWDKPYNMG
Mb0323|M.bovis_AF2122/97 -AAATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFG
Rv0315|M.tuberculosis_H37Rv -AAATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFG
MUL_4744|M.ulcerans_Agy99 -AAGAGPIFLWHDEFDGPAGSAPDPSKWQVSNHRTPIRNPVGFDRPEFWG
MMAR_2902|M.marinum_M -NGQSG-PYLFHDEFDGPAGSAPDSSKWTVARAREEMKDPTYWERPENVG
MAV_2761|M.avium_104 -SGQSG-TYLFQDEFDGPAGSAPDASKWAVAKARETIKDPTYWERPENIG
MAB_1840c|M.abscessus_ATCC_199 -DAQSS-GFVFRDEFDGPAGSAPDGSKWVAAKFRERIKNPVFWDRPENMG
: :: ***:****: *: : * * :::* :::* *
TH_0196|M.thermoresistible__bu RYVTDQEHVFHDGNGNLVIRATRGPGANIREKYASAKIVGLWRGGVGTTW
Mvan_0446|M.vanbaalenii_PYR-1 RYVTDQEHVFQDGNGNLVIRATRGEGANIQEKYASAKIIGNWRGGVGTTW
Mflv_0298|M.gilvum_PYR-GCK RYVTDQEHVFQDGNGNLVIRATRGEGTTIQEKYASAKIMGTWRGGIGTTW
MSMEG_0645|M.smegmatis_MC2_155 RYVTDQEHAFQDGKGNLVIRATRGPGTTIQEKYASAKVVGLWRGGIGTTW
Mb0323|M.bovis_AF2122/97 QYRDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTW
Rv0315|M.tuberculosis_H37Rv QYRDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTW
MUL_4744|M.ulcerans_Agy99 QYRDNRQNVFLDGNSNLVLRATR-SGN----DYFGGLVHGLWRGGIGTTW
MMAR_2902|M.marinum_M QYRDDRQNVFLDGKSNLVIRAAK-DGG----TYYAGKIQSPWRGGIGHTW
MAV_2761|M.avium_104 QYRDDRRNVFLDGKSNLVLRAAK-DGP----TYYSGKVQSLWRGGVGHTW
MAB_1840c|M.abscessus_ATCC_199 EYRDSRTNIFLDGNSNLVIRATK-EGN----KYFSGKLHGTFRGGMGHTF
.* .: : * **:.***:**:: * * .. : . :***:* *:
TH_0196|M.thermoresistible__bu EARVKLNCLTDGAWPAFWLLNDDPVRGAEIDIFEWYGNRDWPSGATVHAK
Mvan_0446|M.vanbaalenii_PYR-1 EARIKLNCLTDGAWPAFWLINDNPVRGGEVDLVEWYGNRDWPSGTTVHAK
Mflv_0298|M.gilvum_PYR-GCK EARVKLDCLTDGAWPAFWLVNENPVRGGEVDLVEWYGNNDWPSGTTVHAR
MSMEG_0645|M.smegmatis_MC2_155 EARVKLNCLTDGAWPAFWLLNDNPVRGGEVDLVEWYGNRDWPSGTTVHAR
Mb0323|M.bovis_AF2122/97 EARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHAN
Rv0315|M.tuberculosis_H37Rv EARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHAN
MUL_4744|M.ulcerans_Agy99 EARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGSWPSGTTVHAN
MMAR_2902|M.marinum_M EARIKFDCLTAGCWPAWWLGNQD---RGEIDIIEWYGNGSWPSATTVHAK
MAV_2761|M.avium_104 EARIKLDCLTAGAWPAYWLGNDD---QGEIDVMEWYGNGNWPSATTVHAK
MAB_1840c|M.abscessus_ATCC_199 EARIKFNCLTDGCWPAWWLLNDNPERGGEIDMAEWYGNRDWPSGTTVHAR
***:*::**: * ***:** *:: .*:*: ***** ***.:****.
TH_0196|M.thermoresistible__bu LDGTMFQTQNYPVDSAWHTWRMTWLPSGMYFWQDYEPGKEPFFTVLAN--
Mvan_0446|M.vanbaalenii_PYR-1 LDGTMFQTHKHPIDSAWHTWRMTWLPTGMYFWKDYQPGMEPFFTVASN--
Mflv_0298|M.gilvum_PYR-GCK LDGTAFATNRHPVDNAWHTWRMTWQPTGLYFWKDYQPGMEPFFTVPAN--
MSMEG_0645|M.smegmatis_MC2_155 LDGTSFATNPHPVDSDWHTWRMSWKPEGMYFWKDYAPGMEPFFSVPAN--
Mb0323|M.bovis_AF2122/97 PDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGI
Rv0315|M.tuberculosis_H37Rv PDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGI
MUL_4744|M.ulcerans_Agy99 PDGTAFETFPIGVDDNWYNWRVTWNVTGMYFWLDYADGMQPYFSVPATGI
MMAR_2902|M.marinum_M ANGSEWKTRNVALDSGWHTWRCQWDETGMRFWQDYAEGAQPYFTVAAH--
MAV_2761|M.avium_104 ANGGEWKTHNIAVDSAWHTWRCQWDEAGIRFWKDYVDGAQPYFDVPAS--
MAB_1840c|M.abscessus_ATCC_199 LDGTSFETLPVPIDSNWHTWRCTWTEAGLYFWMDYHDGMEPYLTVDAN--
:* : * :*. *:.** * *: ** ** * :*:: * :
TH_0196|M.thermoresistible__bu -----SLPEWPFNDPGYTMVPVFNIAVGGSGGREPAGGSYPADMIIDWIR
Mvan_0446|M.vanbaalenii_PYR-1 -----SLPDWPFNDPGYTMAPVFNIAVGGSGGREPAGGTYPAEMLVDWIR
Mflv_0298|M.gilvum_PYR-GCK -----SIPDWPFNDPGFTMVPVFNIAVGGSGGREPAAGTYPAEMRVDWIR
MSMEG_0645|M.smegmatis_MC2_155 -----SLQDWPFNDPGYTMVPVFNIAVGGSGGREPAGGTYPAEMLVDWIR
Mb0323|M.bovis_AF2122/97 EDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVR
Rv0315|M.tuberculosis_H37Rv EDLNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVR
MUL_4744|M.ulcerans_Agy99 EDLNEPIREWPFNDPDYTVFPVLNLAVGGSGGGDPAAGTYPQEMLVDWVR
MMAR_2902|M.marinum_M -----SLPDWPFNDPGYTVFPVLNLAVAGSGGGDPRPGSYPAQMLVDWVR
MAV_2761|M.avium_104 -----SLPDWPFNGPGYTVFPVFNLAVAGSGGGDPGPGSYPADMLIDWIR
MAB_1840c|M.abscessus_ATCC_199 -----SLDDWPFNDPGYTLQPMLNLAVAGSGGGDPAGGSYPAEMLVDYVR
.: :****.*.:.: *::*:**.**** :* *:** :* :*::*
TH_0196|M.thermoresistible__bu VF--
Mvan_0446|M.vanbaalenii_PYR-1 VF--
Mflv_0298|M.gilvum_PYR-GCK VFAS
MSMEG_0645|M.smegmatis_MC2_155 VFAG
Mb0323|M.bovis_AF2122/97 VF--
Rv0315|M.tuberculosis_H37Rv VF--
MUL_4744|M.ulcerans_Agy99 VF--
MMAR_2902|M.marinum_M VW--
MAV_2761|M.avium_104 VW--
MAB_1840c|M.abscessus_ATCC_199 VW--
*: