For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TTFEGTSPARPATPSRDAVSGALKEYVRKHPVQAVETAGSQIVLGVRAMQYMFSDIVHRAFPWREFIHQG AFMAGSAVVPTLLVAIPIGVTLSIQFALLAGQVGASSLAGAASGVAIVRQGASLVAAVLMASAVGSAITA DLGSRTMREEIDAMEVMGVSVIRRLVVPRVAAAVLVGVGLTGTTCFVGFLASYLFNVYFQHGAPGSFVAT FASFTRVDDLVLALLKAILYGLIVAIVACDKGLTTKGGPAGVANSVNAAVVESILVLMLINVLVSQVYVM VFPRHGI*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4601c | - | - | 100% (288) | putative YrbE family protein |
M. abscessus ATCC 19977 | MAB_4518c | - | e-107 | 71.76% (262) | putative YrbE family protein |
M. abscessus ATCC 19977 | MAB_1012c | - | e-106 | 69.85% (262) | putative YrbE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3531c | yrbE4A | 6e-48 | 42.15% (223) | integral membrane protein YrbE4a |
M. gilvum PYR-GCK | Mflv_0012 | - | 1e-108 | 70.74% (270) | hypothetical protein Mflv_0012 |
M. tuberculosis H37Rv | Rv3501c | yrbE4A | 6e-48 | 42.15% (223) | integral membrane protein YrbE4a |
M. leprae Br4923 | MLBr_02587 | yrbE1A | 9e-46 | 41.52% (224) | hypothetical protein MLBr_02587 |
M. marinum M | MMAR_3862 | yrbE5A | 1e-110 | 74.43% (262) | YrbE family protein, YrbE5A |
M. avium 104 | MAV_2390 | - | 1e-107 | 72.52% (262) | hypothetical protein MAV_2390 |
M. smegmatis MC2 155 | MSMEG_1141 | - | 1e-108 | 68.29% (287) | ABC-transporter integral membrane protein |
M. thermoresistible (build 8) | TH_2930 | - | 1e-110 | 73.66% (262) | PUTATIVE protein of unknown function DUF140 |
M. ulcerans Agy99 | MUL_3794 | yrbE5A | 1e-109 | 73.66% (262) | YrbE family protein, YrbE5A |
M. vanbaalenii PYR-1 | Mvan_0957 | - | 1e-109 | 72.52% (262) | hypothetical protein Mvan_0957 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0012|M.gilvum_PYR-GCK MRLPGPRTRCGRRHRRSECTAAERTSGMTTADQPVRRDDSVHAVQDWVGG Mvan_0957|M.vanbaalenii_PYR-1 ---------------------------MSSDTK----GEGVGVITDWAGG MSMEG_1141|M.smegmatis_MC2_155 -----------------MTTSPDRVSDGGAPER------GTDAIEKWATG TH_2930|M.thermoresistible__bu ---------------------------MTRSDG-------VEVIGEWAGG MMAR_3862|M.marinum_M -----------------------MTTQPEPALLGSRNDDGVAAIGDWAAG MUL_3794|M.ulcerans_Agy99 -----------------------MTTQPEPALLGSRNDDGVAAIGDWAAG MAV_2390|M.avium_104 -----------------------MTATLTTPLDG---VDGVAAIRNWSVG MAB_4601c|M.abscessus_ATCC_199 ------------------MTTFEGTSPARPATP------SRDAVSGALKE Mb3531c|M.bovis_AF2122/97 -------------------------------------------------- Rv3501c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02587|M.leprae_Br4923 ---------------------------------------MTTETRSSLVE Mflv_0012|M.gilvum_PYR-GCK YVRRHPLASLATVGDQFVLGVRTLQWFFVDLFTGRFQFQEFVRQGAFMAG Mvan_0957|M.vanbaalenii_PYR-1 YVKRHPLASLTTVGDQFVLGVRTVQYFLLDLFSGRFQWQEFIRQGAFMAG MSMEG_1141|M.smegmatis_MC2_155 YVRRHPIASLTTVGDQFVLGVRTVQYLFTELFTGRFQWQEFIRQGAFMAS TH_2930|M.thermoresistible__bu YIRRHPLAALGTVGEQFVLGVRTLQYLFVDLFTGRFQWWEFVRQAAFMAG MMAR_3862|M.marinum_M YVRRHPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFVRQGAFMAG MUL_3794|M.ulcerans_Agy99 YIRRHPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFVRQGAFMAG MAV_2390|M.avium_104 YVKRHPVASLTTVGEQFVLGVRTIQYFFYDLITGRFQWQEFVRQGAFMAG MAB_4601c|M.abscessus_ATCC_199 YVRKHPVQAVETAGSQIVLGVRAMQYMFSDIVHRAFPWREFIHQGAFMAG Mb3531c|M.bovis_AF2122/97 -MIQQLAVPARAVGGFFEMSMDTARAAFR----RPFQFREFLDQTWMVAR Rv3501c|M.tuberculosis_H37Rv -MIQQLAVPARAVGGFFEMSMDTARAAFR----RPFQFREFLDQTWMVAR MLBr_02587|M.leprae_Br4923 YAHTKLQTPLVLVGGFFRMLVLTGKALFR----RPFQWREFILQCWFIMR : . .* : : : : : : * : **: * :: Mflv_0012|M.gilvum_PYR-GCK TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT Mvan_0957|M.vanbaalenii_PYR-1 TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT MSMEG_1141|M.smegmatis_MC2_155 TAVVPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT TH_2930|M.thermoresistible__bu TAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAVIRQAASLT MMAR_3862|M.marinum_M TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV MUL_3794|M.ulcerans_Agy99 TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV MAV_2390|M.avium_104 TAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLV MAB_4601c|M.abscessus_ATCC_199 SAVVPTLLVAIPIGVTLSIQFALLAGQVGASSLAGAASGVAIVRQGASLV Mb3531c|M.bovis_AF2122/97 VSLVPTLLVSIPFTVLVAFTLNILLREIGAADLSGAGTAFGTITQLGPVV Rv3501c|M.tuberculosis_H37Rv VSLVPTLLVSIPFTVLVAFTLNILLREIGAADLSGAGTAFGTITQLGPVV MLBr_02587|M.leprae_Br4923 VAFLPTVMVSIPLTVLLIFTLNVLLAQFSAADLSGAGAAIGAVTQLGPLT :.:**::*::*: * : : : :* :..*:.*:**.:... : * ..:. Mflv_0012|M.gilvum_PYR-GCK AAILMAAAVGSAITADLGSRKMREETDAMEVMGVSVIRRLVVPRFAAAIM Mvan_0957|M.vanbaalenii_PYR-1 AAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM MSMEG_1141|M.smegmatis_MC2_155 AAVLMAAAVGSAITADLGSRKMREETDAMEVMGVSVIKRLVVPRFAAAIM TH_2930|M.thermoresistible__bu AAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM MMAR_3862|M.marinum_M AAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAIM MUL_3794|M.ulcerans_Agy99 AAVLMASAVGSAITADLGSRTMREETDAMEVMGLSVIRRLVVPRFAAAIM MAV_2390|M.avium_104 AAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVVRRLVVPRFAAAVM MAB_4601c|M.abscessus_ATCC_199 AAVLMASAVGSAITADLGSRTMREEIDAMEVMGVSVIRRLVVPRVAAAVL Mb3531c|M.bovis_AF2122/97 TVLVVAGAGATAICADLGARTIREEIDAMRVLGIDPIQRLVVPRVLASTL Rv3501c|M.tuberculosis_H37Rv TVLVVAGAGATAICADLGARTIREEIDAMRVLGIDPIQRLVVPRVLASTL MLBr_02587|M.leprae_Br4923 TVLVVAGAGSTSICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLAATL :.:::*.* .::* ****:*.:*** ***.*:*:. ::******. *: : Mflv_0012|M.gilvum_PYR-GCK IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATTGDMIVALV Mvan_0957|M.vanbaalenii_PYR-1 IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATTGDMIVALV MSMEG_1141|M.smegmatis_MC2_155 IGVALTGVVCFVGFIASFLFNVYFQDGAPGSFVATFASFATTGDMIVALI TH_2930|M.thermoresistible__bu IGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFTTTGDMLVALI MMAR_3862|M.marinum_M IGVALTGVVCFVGFFASYMFNVYFQNGAPGSFVATFASFATTDDMFLALF MUL_3794|M.ulcerans_Agy99 IGVALTGVVCFVGFFASYMFNVYFQNGAPGSFVATFASFATTDDMFLALF MAV_2390|M.avium_104 IGVALTGVVCFAGFFASYMFNVYFQNGAPGSFVSTSASFATTGDMILALL MAB_4601c|M.abscessus_ATCC_199 VGVGLTGTTCFVGFLASYLFNVYFQHGAPGSFVATFASFTRVDDLVLALL Mb3531c|M.bovis_AF2122/97 VALLLNGLVCAIGLSGGYAFSVFLQGVNPGAFINGLTVLTGLRELILAEI Rv3501c|M.tuberculosis_H37Rv VALLLNGLVCAIGLSGGYAFSVFLQGVNPGAFINGLTVLTGLRELILAEI MLBr_02587|M.leprae_Br4923 VATLLNGLVITVGLVGGYLFGVYLQNVSGGAYLATLTTITGLPEVVIATV :. *.* . *: ..: *.*::* *::: : :: ::.:* . Mflv_0012|M.gilvum_PYR-GCK KAVIFGAIVAIVSCQKGLSTQGGPTGVANSVNAAVVESILVLMVVNVAIS Mvan_0957|M.vanbaalenii_PYR-1 KAVIFGAIVAVVSCQKGLATQGGPTGVANSVNAAVVESILLLMVVNVAIS MSMEG_1141|M.smegmatis_MC2_155 KAVIFGAIVAVVSCQKGLSTVGGPTGVANSVNAAVVESILLLMVVNVAIS TH_2930|M.thermoresistible__bu KAVVFGAIVAVVSCQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVGIS MMAR_3862|M.marinum_M KAVIFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVSIS MUL_3794|M.ulcerans_Agy99 KAVMFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVLMIVNVSIS MAV_2390|M.avium_104 KAIVFGAIVAIVSSQKGLSTKGGPTGVANSVNAAVVEAILLLMIVNVAIS MAB_4601c|M.abscessus_ATCC_199 KAILYGLIVAIVACDKGLTTKGGPAGVANSVNAAVVESILVLMLINVLVS Mb3531c|M.bovis_AF2122/97 KALLFGVMAGLVGCYRGLTVKGGPKGVGNAVNETVVYAFICLFVINVVMT Rv3501c|M.tuberculosis_H37Rv KALLFGVMAGLVGCYRGLTVKGGPKGVGNAVNETVVYAFICLFVINVVMT MLBr_02587|M.leprae_Br4923 KAATFGLIAGLVGCYRGLIVRGGSNGLGAAVNETVVLCVVALYAVNVVLT ** :* :..:*.. :** . **. *:. :** :** ..: * :** :: Mflv_0012|M.gilvum_PYR-GCK QLYILMFPRVGL Mvan_0957|M.vanbaalenii_PYR-1 QLYIMMFPRVGL MSMEG_1141|M.smegmatis_MC2_155 QLYIMLFPRVGL TH_2930|M.thermoresistible__bu QLYIMLFPRVGL MMAR_3862|M.marinum_M QLHVMLAPRTGL MUL_3794|M.ulcerans_Agy99 QLHVMLAPRTGL MAV_2390|M.avium_104 QLYIMLSPRTGL MAB_4601c|M.abscessus_ATCC_199 QVYVMVFPRHGI Mb3531c|M.bovis_AF2122/97 AIGVRISAQ--- Rv3501c|M.tuberculosis_H37Rv AIGVRISAQ--- MLBr_02587|M.leprae_Br4923 TIGVRFGTGH-- : : . .