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VDVSGGSFSASGRGWSDRALLLAGVAVLAILGLVTGLLLAKSKGYLEDTVKVDAQLMNVGDGLPERADVK FRGMLVGAVTSVTPAEDGKPNIVHIDLKSEHAGGIPSTVTARVVPSNVFAVSSVQLVDNGDGAGIRNGAI ITEDTKLPTVLFQTTTNKLRQVLAATERQRGDPPVGLIGVFGEATQGRGNKLLSSGARLQAILTEFNAMV TASPNDPSTIAALEKVSDALSTTSPRLLDNLENALVPLRTLAQKKDDVRGLLSAGLHTTGTTATAIDNHI DQMIGIGTHLTPVVGVLAQNADKFVPIATRVRALSDAAFANGWDPGRQVIGLNLILSFSPAWTYVRDDCP RYGELAGPSCTTAPETRQWIDIPEVLQPGSYKPPPDIAPPPGTVFPPPAADIMLHGTGPNPQEVDRAANP VLPPFGPPPNPAPAPVAPASFGGNVGPVGSAVEREQLGKALGGDASTSQQLLLGPVARGTTISVSRDESA ADAAQPNSAQLNSGQGGGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4599c | - | - | 100% (510) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_4568c | - | e-133 | 51.28% (507) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_1695 | - | e-128 | 51.35% (483) | putative Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0175 | mce1A | 6e-09 | 23.66% (262) | MCE-family protein MCE1A |
| M. gilvum PYR-GCK | Mflv_0010 | - | 1e-118 | 45.49% (543) | hypothetical protein Mflv_0010 |
| M. tuberculosis H37Rv | Rv0169 | mce1A | 6e-09 | 23.66% (262) | MCE-family protein MCE1A |
| M. leprae Br4923 | MLBr_02589 | mce1A | 5e-08 | 21.26% (254) | putative cell invasion protein |
| M. marinum M | MMAR_0177 | mce6A | 1e-118 | 50.10% (479) | MCE-family protein Mce6A |
| M. avium 104 | MAV_0102 | - | 1e-129 | 50.69% (509) | mce related protein |
| M. smegmatis MC2 155 | MSMEG_1143 | - | 1e-126 | 48.09% (524) | mce related protein |
| M. thermoresistible (build 8) | TH_2386 | - | 1e-109 | 47.58% (454) | mce related protein |
| M. ulcerans Agy99 | MUL_4919 | mce6A | 1e-118 | 50.31% (479) | MCE-family protein Mce6A |
| M. vanbaalenii PYR-1 | Mvan_0959 | - | 1e-120 | 46.46% (523) | hypothetical protein Mvan_0959 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1143|M.smegmatis_MC2_155 ----MGNSIELDGRGPSERQLLACGLAVLVVAGLISTVLLVKATGRLDPY
TH_2386|M.thermoresistible__bu ----MANSFDLDGRGPTDRQLLAGGVVVIVVLSVISTYLLVKATGRLDPF
Mflv_0010|M.gilvum_PYR-GCK ----MANSFEFDGRGPSDRQLLVCGVAVLAIVSIVTAVLLVKSTGRLDPR
Mvan_0959|M.vanbaalenii_PYR-1 ----MANSLEMDGRGPTDRQLLACGVALLVIALVVSGALLVKSTGRMDAH
MAV_0102|M.avium_104 ----MANSLDFDGRGPTDHQLLALGATVLLIAGLITGGLLLKSTGRLNDY
MMAR_0177|M.marinum_M ----MTNHIDLDGIYFSKRQLLARGGIALVVVLLVTSWLLAKSMGYLDRG
MUL_4919|M.ulcerans_Agy99 ----MTNHIDLDGIYFSKRQLLARGGIALVVVLLVTSWLLAKSMGYLDRG
MAB_4599c|M.abscessus_ATCC_199 MVDVSGGSFSASGRGWSDRALLLAGVAVLAILGLVTGLLLAKSKGYLEDT
Mb0175|M.bovis_AF2122/97 ----MTTPGKLN--KARVPPYKTAGLGLVLVFALVVALVYLQFRGEFTPK
Rv0169|M.tuberculosis_H37Rv ----MTTPGKLN--KARVPPYKTAGLGLVLVFALVVALVYLQFRGEFTPK
MLBr_02589|M.leprae_Br4923 ----MTSSTKIN--ASRKPPYKLAGVGLLVVAVVIFGLVYGQFRGNFTPK
. . * : : :: : : * :
MSMEG_1143|M.smegmatis_MC2_155 VRVVAALINVGDGLPQRSDVKYHGVLVGMVEDVTPAAHG--EPNYVHINL
TH_2386|M.thermoresistible__bu VRVVADLVNVGDGLPQRSDVKYHGVLVGHVDSVTPAAHG--HPNYVHINL
Mflv_0010|M.gilvum_PYR-GCK VRVVAAMVNVGDGLPQRSDVKYHGVLVGAVDDVTPAENG--EPNFVHIDL
Mvan_0959|M.vanbaalenii_PYR-1 VRVVAALVNVGDGLPQRSDVKYHGVLVGAVDDVTPAQYG--DPNFVHIDL
MAV_0102|M.avium_104 IRVVAELTNVGDGLPARSDVKYHGLLVGAVDNVIPAAYG--KPNYVHINL
MMAR_0177|M.marinum_M VQVVADLRNIGDGLPAGSDVKYRGIQVGTVESLDPSIGN--QPNQVRIRL
MUL_4919|M.ulcerans_Agy99 VQVVADLRNIGDGLPAGSDVKYRGIQVGTVESLDPSIGN--QPNQVRIRL
MAB_4599c|M.abscessus_ATCC_199 VKVDAQLMNVGDGLPERADVKFRGMLVGAVTSVTPAEDG--KPNIVHIDL
Mb0175|M.bovis_AF2122/97 TQLTMLSARAGLVMDPGSKVTYNGVEIGRVDTISEVTRDGESAAKFILDV
Rv0169|M.tuberculosis_H37Rv TQLTMLSARAGLVMDPGSKVTYNGVEIGRVDTISEVTRDGESAAKFILDV
MLBr_02589|M.leprae_Br4923 SKLTMLADRAGLVMDRGSKITYNGVKIGRVADISETVRNGRPVAEFTLDV
:: . * : :.:.:.*: :* * : . . : :
MSMEG_1143|M.smegmatis_MC2_155 NPEYASSIPSTVTARVVPSNVFAVSSVQLVDRDGGAGPAISAGAQIPEDT
TH_2386|M.thermoresistible__bu DRHHARSIPATVTARVVPSNVFAVSSVQLVDRDGGPGTPIQAGAHIPEDT
Mflv_0010|M.gilvum_PYR-GCK KPEYAKSIPANVTARVVPSNVFAVSSVQLVG-SGGP--PIQPGAEIPEDT
Mvan_0959|M.vanbaalenii_PYR-1 KPEYAASIPAGVTARVVPSNVFAVSSVQLVDRSGGP--PIQSGARIPEDT
MAV_0102|M.avium_104 KPEYAQDIPSAVTARVVPSNVFAVSSVQLVDGAPGP--SIRNGARIPEDL
MMAR_0177|M.marinum_M KPEYAASIPVTVTARVVPSNVFAVSSIQLVEHGPGA--PISDGERISEDT
MUL_4919|M.ulcerans_Agy99 KPEYAASIPVTVTARVVPSNVFAVSSIQLVEHGPGT--PISDGERISEDT
MAB_4599c|M.abscessus_ATCC_199 KSEHAGGIPSTVTARVVPSNVFAVSSVQLVDNGDGAG--IRNGAIITEDT
Mb0175|M.bovis_AF2122/97 DPRYIHLIPANVNADIKATTVFGGKYVSLTTPKNPT------KRRITPKD
Rv0169|M.tuberculosis_H37Rv DPRYIHLIPANVNADIKATTVFGGKYVSLTTPKNPT------KRRITPKD
MLBr_02589|M.leprae_Br4923 YPRYLSLIPANVNADIKATTVFGGKYVSLTTPEHPS------QKRLTPQT
.: ** *.* : .:.**. . :.*. . :. .
MSMEG_1143|M.smegmatis_MC2_155 ELPTVLFQTTISKLRDILAATGRGREDRTVG-VLAAVNAATEGRRTELLT
TH_2386|M.thermoresistible__bu ELPTVLFQTTISKLRDILAATGRGREDRTVG-ILAAVNAATENRRTELLS
Mflv_0010|M.gilvum_PYR-GCK ELPTVLFQTTISKLRDILAATGRGREDDTVG-ILAAVHAATEDRRTELLT
Mvan_0959|M.vanbaalenii_PYR-1 ELPTVLFQTTISKLRDILAATGRGREDDTVG-ILAAVNAATEDRRTELLT
MAV_0102|M.avium_104 QLSTVIFQTTISKLRDILAATGRGREDHSVG-ILAAVAAATNNRRGPLLT
MMAR_0177|M.marinum_M DLPTVLFQTALTKLRDILAAAGRNRDDHTLG-VLAAVGAATNNRNGALQL
MUL_4919|M.ulcerans_Agy99 DLPTVLFQTALTKLRDILAAAGRNRDDHTLG-VLAAVGAATNNRNGALQL
MAB_4599c|M.abscessus_ATCC_199 KLPTVLFQTTTNKLRQVLAATERQRGDPPVG-LIGVFGEATQGRGNKLLS
Mb0175|M.bovis_AF2122/97 VIDVRSVTTEINTLFQTLTSIAEKVDPVKLNLTLSAAAEALTGLGDKFGE
Rv0169|M.tuberculosis_H37Rv VIDVRSVTTEINTLFQTLTSIAEKVDPVKLNLTLSAAAEALTGLGDKFGE
MLBr_02589|M.leprae_Br4923 VIDARSVTTEINTLFQTITLIAEKVDPIKLNLTLSAAAQSLAGLGERFGQ
: . . * ..* : :: . :. :.. : . :
MSMEG_1143|M.smegmatis_MC2_155 SGAQLNRLIDEVDSIVATDPSAPTTVSTLIEATRGLQQTAPELVDALHTA
TH_2386|M.thermoresistible__bu AGAQLDLLIDEIDSIVATDP-GPTTVSALIGATRGLQQTAPELLDALHQA
Mflv_0010|M.gilvum_PYR-GCK SGAQLNRMVDELDRIVATEP-GPTTVSALVDATRGLQQTAPELVDALHQA
Mvan_0959|M.vanbaalenii_PYR-1 SGAQLNSLVDELDRIVATDP-GPTTVSALVDATRGLQQTAPELVDALHQA
MAV_0102|M.avium_104 AGAQLTRVLDELNAIVATDP-GPSTVSALLDATRGLQSTAPDLVDVLHDA
MMAR_0177|M.marinum_M STHQLIRIIDELNGVVATDQ-GPSTVAALVDAARGLSQSAPELLDAFHDA
MUL_4919|M.ulcerans_Agy99 STHQLIRIIDELNGVVATDE-GPSTVAALVDAARGLSQSAPELLDALHDA
MAB_4599c|M.abscessus_ATCC_199 SGARLQAILTEFNAMVTASPNDPSTIAALEKVSDALSTTSPRLLDNLENA
Mb0175|M.bovis_AF2122/97 SIVNANTVLDDLNSRMPQSR---HDIQQLAALGDVYADAAPDLFDFLDSS
Rv0169|M.tuberculosis_H37Rv SIVNANTVLDDLNSRMPQSR---HDIQQLAALGDVYADAAPDLFDFLDSS
MLBr_02589|M.leprae_Br4923 SIVNGNSVLDDVNSQLPQAR---HDIQQLASLGDTYANSASDFFDFLNNS
: . :: :.: :. : * ::. :.* :. :
MSMEG_1143|M.smegmatis_MC2_155 VRPMQTLVEQRSQLDSLISAGMNTLDTTRTALNNHTDRLVKITSELTPVV
TH_2386|M.thermoresistible__bu VQPMQTLVQQRAQLDALIGGALHTSATTHTALTNHTDRMVTITTEMTPVI
Mflv_0010|M.gilvum_PYR-GCK VQPMQTLVEQSAQLTSLVNGGIRTSETTRTAFDNHADRLVRITTELTPVV
Mvan_0959|M.vanbaalenii_PYR-1 VEPMQTLVEQSAQLTTFINGGINTVGTTHTALNNHTDRMVRITTELTPVI
MAV_0102|M.avium_104 VRPMQTLVEKREQFRSLVTGSYHTFSVNRQAFDNHTDQLIEMTQNLTPVL
MMAR_0177|M.marinum_M VAPMRTLVDKQQALHDFLGAGQYTTGLAVNSLQNHSDQLVQITTDLTPVV
MUL_4919|M.ulcerans_Agy99 VAPMRTLVDKQQALHDFLGAGQYTTGLAANSLQNHSDQLVQITTDLTPVV
MAB_4599c|M.abscessus_ATCC_199 LVPLRTLAQKKDDVRGLLSAGLHTTGTTATAIDNHIDQMIGIGTHLTPVV
Mb0175|M.bovis_AF2122/97 VTTARTINAQQAELDSALLAAAGFGNTTADVFDRGGPYLQRGVADLVPTA
Rv0169|M.tuberculosis_H37Rv VTTARTINAQQAELDSALLAAAGFGNTTADVFDRGGPYLQRGVADLVPTA
MLBr_02589|M.leprae_Br4923 IVTSRTINQQQKDLDQVLLAAVGFGNTGADIFSRSGPYLARGAADLVPTA
: . :*: : . : .. : . : .:.*.
MSMEG_1143|M.smegmatis_MC2_155 GNLADTSHHWLPAFVKLNNLSDKFFDEVWRPERNVGNMRMNLSFTPSYTY
TH_2386|M.thermoresistible__bu GNLADTSHHWLPAFIKMNGLSDKFFEEVWRPERDIGNMRMNLSLTPSYTY
Mflv_0010|M.gilvum_PYR-GCK GSLADTSRHWVPAFVKLNELSRKFFDEVWIHEHDIGNMRINLSFTPTYSY
Mvan_0959|M.vanbaalenii_PYR-1 GNLAQTSHHWVPAFVKLNGLSRKFFDEVWMHDRDVGNMRVNLSFTPTYSY
MAV_0102|M.avium_104 GVFAMNSDKFVPIFTRLNRLSDKFFQEVWDPELDTGNMRVNLALTPTYTY
MMAR_0177|M.marinum_M GVFADNAQHFVPITERITRFSDKFFEEVWDPASTVAHGRVNVSFTPSYTY
MUL_4919|M.ulcerans_Agy99 GVFADNAQHFVPITERITRFSDKFFEEVWDPASTVAHGRVNVSFTPSYTY
MAB_4599c|M.abscessus_ATCC_199 GVLAQNADKFVPIATRVRALSDAAFANGWDPGRQVIGLNLILSFSPAWTY
Mb0175|M.bovis_AF2122/97 TLLDTYSPELFCTIRNFYDADP--LAKAAAGGGNGYSLRTNSEILSGIGI
Rv0169|M.tuberculosis_H37Rv TLLDTYSPELFCTIRNFYDADP--LAKAASGGGNGYSLRTNSEILSGIGI
MLBr_02589|M.leprae_Br4923 QLLDTYSPAIFCTLRNYHDIEP--KVTSFLGG-NGYSINDHVELLSGLGF
: : . . . . : .
MSMEG_1143|M.smegmatis_MC2_155 TRADCPQYGELKGPSCFTAPLVVTRPALPDQMLPRNYQPPKDLAPPPGTV
TH_2386|M.thermoresistible__bu TRADCPRYGELKGPSCYTAPLVVTRPSLPDVLLPQNYQPPKDLAPPPGTI
Mflv_0010|M.gilvum_PYR-GCK TRADCPQYAGLKGPSCYTAPLVPTRAALPDVLLPQNYQPPKDLQPPPGTE
Mvan_0959|M.vanbaalenii_PYR-1 TRADCPQYGELKGPSCFTAPLVPTRPELPDVLLPQNYQPPADLKPPPGTE
MAV_0102|M.avium_104 TRADCPRYGQLQGPSCFTAPTIAVRPDLPEVLLPQNYHPPTDLAPPPGTQ
MMAR_0177|M.marinum_M TRADCPRYGELRAPSCFTAPLVQARPDLPEVLLPQNYQPPPNLAPPPGTV
MUL_4919|M.ulcerans_Agy99 TRADCPRYGELRAPSCFTAPLVQARPDLPEVLLPQNYQPPPNLAPPPGTV
MAB_4599c|M.abscessus_ATCC_199 VRDDCPRYGELAGPSCTTAPETRQWIDIPEVLQPGSYKPPPDIAPPPGTV
Mb0175|M.bovis_AF2122/97 S---------LLSPLALATNGAAIGIGLVAGLIASPLAVAANLAGALPGI
Rv0169|M.tuberculosis_H37Rv S---------LLSPLALATNGAAIGIGLVAGLIAPPLAVAANLAGALPGI
MLBr_02589|M.leprae_Br4923 L---------LNPTSAISIIGAGV---LSQGLLAP-------LG--LAGV
* . . : : : . :
MSMEG_1143|M.smegmatis_MC2_155 VGENGNLVAVGPPLINPNPSLADPNPPLPPW-----MAPAPPVPGTANSA
TH_2386|M.thermoresistible__bu VGENGNLVAVGPPLVNPNPNLADPNPPLPPG-----MFPAPPVPGTSNPD
Mflv_0010|M.gilvum_PYR-GCK IGPSGNLIAVGPPLVNPNPSLADPNPPLPPW-----MPPSPPVPLTANPA
Mvan_0959|M.vanbaalenii_PYR-1 VGPNGNLVAVGPPLVNPNPDLRDPNPPLPPW-----LSPSPPVPGTANPA
MAV_0102|M.avium_104 IGPDGNLVATGPPLYNPDPSLADPNPPLPWWPW--QIGPAPRVPGTADPD
MMAR_0177|M.marinum_M VGPDGNLVAVGPPLINPTPNLEDPNPPLPAG-----VTPAPPVPGTANPD
MUL_4919|M.ulcerans_Agy99 VGPDGNLVAVGPPLINPTPNLEDPNPPLPAG-----VTPAPPVPGTANPD
MAB_4599c|M.abscessus_ATCC_199 FPPPAADIMLHGTGPNPQEVDRAANPVLPPFGPPP------------NPA
Mb0175|M.bovis_AF2122/97 VGGAPNPYTYPENLPRVNARGGPGGAPGCWQPITRDLWPAPYLVMDTGAS
Rv0169|M.tuberculosis_H37Rv VGGAPNPYTYPENLPRVNARGGPGGAPGCWQPITRDLWPAPYLVMDTGAS
MLBr_02589|M.leprae_Br4923 VNGAANPYIYPENLPRVNARGGPGGAPGCWQHITRDLWPTPELVMDTGNS
. . .. .
MSMEG_1143|M.smegmatis_MC2_155 LPVTPPPGVNQSPLAPVAPKPGSPPPPPPAPG-----PLPAEAAPA----
TH_2386|M.thermoresistible__bu LVPIPPPPVNLSPLAPVAPNPNKPRPPVPAPP-----PAP----------
Mflv_0010|M.gilvum_PYR-GCK LVPPPQLPAPLSPPAPVAPKPGDPPPRPAAPAPAAPAPAPAAPAPAPAAP
Mvan_0959|M.vanbaalenii_PYR-1 LVPVPQPPVPLSPPAPVAPKPGDPPPPPAAPPVSGPAPLPAEAAPA----
MAV_0102|M.avium_104 DAPPPPPPSP--PPSPAPPGPVAPAA------------------------
MMAR_0177|M.marinum_M LLPAAPSS------------------------------------------
MUL_4919|M.ulcerans_Agy99 LLPAAPSS------------------------------------------
MAB_4599c|M.abscessus_ATCC_199 PAPVAPAS------------------------------------------
Mb0175|M.bovis_AF2122/97 LAPYNHMEVG----------------------------------------
Rv0169|M.tuberculosis_H37Rv LAPYNHMEVG----------------------------------------
MLBr_02589|M.leprae_Br4923 IAPYNHLDSG----------------------------------------
MSMEG_1143|M.smegmatis_MC2_155 ------------SFGGNVGPVGSEQERVTLSVITGQ--PASTATQLLLGP
TH_2386|M.thermoresistible__bu --------------GG----------------------------------
Mflv_0010|M.gilvum_PYR-GCK GPGSAEAPFAPASFGGNVGPVGSQQEQRQLSLITGR--HATPATQLLLGP
Mvan_0959|M.vanbaalenii_PYR-1 ------------GYGGNVGPVGSRHELDQLGYITGQ--PATVATQLLLGP
MAV_0102|M.avium_104 -------------YGGNVGPVGSQRERDQLGLITGQGRPASVATQLLLGP
MMAR_0177|M.marinum_M -------------FGGNVGPVGSVQERAALSLITGE--QATVATQLLLGP
MUL_4919|M.ulcerans_Agy99 -------------FGGNVGPVGSVQERAALSLITGE--QATVATQLLLGP
MAB_4599c|M.abscessus_ATCC_199 -------------FGGNVGPVGSAVEREQLGKALGG--DASTSQQLLLGP
Mb0175|M.bovis_AF2122/97 ---------------------------------------SPYAVEYVWGR
Rv0169|M.tuberculosis_H37Rv ---------------------------------------SPYAVEYVWGR
MLBr_02589|M.leprae_Br4923 ---------------------------------------SPYAIEYVWGR
MSMEG_1143|M.smegmatis_MC2_155 VARGTTVSLAEPTAGEEPR---------------
TH_2386|M.thermoresistible__bu --------------GEEPR---------------
Mflv_0010|M.gilvum_PYR-GCK LARGTTVS-----IDGEP----------------
Mvan_0959|M.vanbaalenii_PYR-1 VARGTTVS-----EGVR-----------------
MAV_0102|M.avium_104 VARGSAVSLQPRPAPGGPK---------------
MMAR_0177|M.marinum_M VARGAIASRTQQTPTESK----------------
MUL_4919|M.ulcerans_Agy99 VARGAIASRTQQTPTESK----------------
MAB_4599c|M.abscessus_ATCC_199 VARGTTISVSRDESAADAAQPNSAQLNSGQGGGR
Mb0175|M.bovis_AF2122/97 QVGDNTINP-------------------------
Rv0169|M.tuberculosis_H37Rv QVGDNTINP-------------------------
MLBr_02589|M.leprae_Br4923 QVGDNTINP-------------------------