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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2386 | - | - | 100% (480) | mce related protein |
| M. thermoresistible (build 8) | TH_1738 | - | 7e-12 | 23.90% (523) | MCE-FAMILY PROTEIN MCE4F |
| M. thermoresistible (build 8) | TH_3624 | - | 5e-10 | 24.63% (268) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3906 | - | 2e-09 | 31.11% (180) | hypothetical protein Mb3906 |
| M. gilvum PYR-GCK | Mflv_0010 | - | 0.0 | 74.31% (471) | hypothetical protein Mflv_0010 |
| M. tuberculosis H37Rv | Rv3876 | - | 2e-09 | 31.11% (180) | hypothetical protein Rv3876 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 9e-07 | 34.09% (88) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_1010c | - | 1e-165 | 63.76% (458) | putative MCE family protein |
| M. marinum M | MMAR_3864 | mce5A | 1e-174 | 63.33% (480) | Mce protein, Mce5A |
| M. avium 104 | MAV_2388 | - | 0.0 | 64.79% (480) | mce related protein |
| M. smegmatis MC2 155 | MSMEG_1143 | - | 0.0 | 79.92% (473) | mce related protein |
| M. ulcerans Agy99 | MUL_3796 | mce5A | 1e-173 | 63.33% (480) | Mce protein, Mce5A |
| M. vanbaalenii PYR-1 | Mvan_0959 | - | 0.0 | 77.47% (475) | hypothetical protein Mvan_0959 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2386|M.thermoresistible__bu MANSFDLDGR------GPTDRQLLAGGVVVIVVLSVISTYLLVKATG---
MSMEG_1143|M.smegmatis_MC2_155 MGNSIELDGR------GPSERQLLACGLAVLVVAGLISTVLLVKATG---
Mflv_0010|M.gilvum_PYR-GCK MANSFEFDGR------GPSDRQLLVCGVAVLAIVSIVTAVLLVKSTG---
Mvan_0959|M.vanbaalenii_PYR-1 MANSLEMDGR------GPTDRQLLACGVALLVIALVVSGALLVKSTG---
MMAR_3864|M.marinum_M MPNSIESDGR------GPSDRQLIGIGLVVVLLAAVLTIALLVKSTG---
MUL_3796|M.ulcerans_Agy99 MPNSIESDGC------GPSDRQLIGIGLVVVLLAAVLTIALLVKSTG---
MAV_2388|M.avium_104 MPNSFELDGR------GPSDRQLFGIGIAVLVVSALLTTVMLVKSTG---
MAB_1010c|M.abscessus_ATCC_199 -----------------------------MIVVAALVTGLMLLKSTG---
Mb3906|M.bovis_AF2122/97 MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
Rv3876|M.tuberculosis_H37Rv MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_2386|M.thermoresistible__bu --RLDPFVRVVADLVNVGDGLPQRSDVKYHGVLVGHVDSVTPAAHGHPNY
MSMEG_1143|M.smegmatis_MC2_155 --RLDPYVRVVAALINVGDGLPQRSDVKYHGVLVGMVEDVTPAAHGEPNY
Mflv_0010|M.gilvum_PYR-GCK --RLDPRVRVVAAMVNVGDGLPQRSDVKYHGVLVGAVDDVTPAENGEPNF
Mvan_0959|M.vanbaalenii_PYR-1 --RMDAHVRVVAALVNVGDGLPQRSDVKYHGVLVGAVDDVTPAQYGDPNF
MMAR_3864|M.marinum_M --RLNDYVRVTADLRNVGDGLPKRSDVKYHGVLVGMVDGVAPAANGRPNY
MUL_3796|M.ulcerans_Agy99 --RLNDYVRVTADLRNVGDGLPKRSDVKYHGVLVGMVDGVAPAANGRPNY
MAV_2388|M.avium_104 --RLDDYVRVVADLVNVGDGLPQKSDVKYHGVLVGMVDDVVPAAHGKPNY
MAB_1010c|M.abscessus_ATCC_199 --RLNDFVRVVADLNNVGDGLPQKSDVKYHGVLVGEVDGVTPASNGQPNF
Mb3906|M.bovis_AF2122/97 PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
Rv3876|M.tuberculosis_H37Rv PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
MLBr_02395|M.leprae_Br4923 -----------MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELG-SAY
. * . *: .
TH_2386|M.thermoresistible__bu VHINLDRHHARSIPATVTARVVPSN-------------VFAVSSVQLVDR
MSMEG_1143|M.smegmatis_MC2_155 VHINLNPEYASSIPSTVTARVVPSN-------------VFAVSSVQLVDR
Mflv_0010|M.gilvum_PYR-GCK VHIDLKPEYAKSIPANVTARVVPSN-------------VFAVSSVQLVG-
Mvan_0959|M.vanbaalenii_PYR-1 VHIDLKPEYAASIPAGVTARVVPSN-------------VFAVSSVQLVDR
MMAR_3864|M.marinum_M VHINLKPEYAASIPAAVTARVVPSS-------------VFAVSSVQLIDA
MUL_3796|M.ulcerans_Agy99 VHINLKPEYAASIPAAVTARVVPSS-------------VFAVSSVQLIDA
MAV_2388|M.avium_104 VHINLKEDYAKSIPASVTARVVPSN-------------VFAVSSVQLVGN
MAB_1010c|M.abscessus_ATCC_199 VHINLKPQYAKSIPSTATARVVPSN-------------VFAVSSVQLVDR
Mb3906|M.bovis_AF2122/97 PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
Rv3876|M.tuberculosis_H37Rv PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
MLBr_02395|M.leprae_Br4923 PPPTAPPVGGSYPPPPPPGGSYPPP-------------------------
. *. . .
TH_2386|M.thermoresistible__bu --DGGPGTPIQAGAHIPEDTELPTVLFQTTISKLRDILAATGR----GRE
MSMEG_1143|M.smegmatis_MC2_155 --DGGAGPAISAGAQIPEDTELPTVLFQTTISKLRDILAATGR----GRE
Mflv_0010|M.gilvum_PYR-GCK --SGGP--PIQPGAEIPEDTELPTVLFQTTISKLRDILAATGR----GRE
Mvan_0959|M.vanbaalenii_PYR-1 --SGGP--PIQSGARIPEDTELPTVLFQTTISKLRDILAATGR----GRE
MMAR_3864|M.marinum_M PAPRGRQPAIRAGTHIPEDSRLPTVLFQTTLSKLRDLLAAAGR----GRE
MUL_3796|M.ulcerans_Agy99 PAPRGRQPAIRAGTHIPEDSRLPTVLFQTTVSKLRDLLAAAGR----GRE
MAV_2388|M.avium_104 ----GPGSKIRDGAHIPEDKRLPTVLFQTTVSKLRDLLAAAGR----GRD
MAB_1010c|M.abscessus_ATCC_199 ----GPGAPIRAGAHIAEDTQLPTVLFQTTVSKLRDVLVATGR----GRD
Mb3906|M.bovis_AF2122/97 APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
Rv3876|M.tuberculosis_H37Rv APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
MLBr_02395|M.leprae_Br4923 --------PPPGGSYPPPPPSTGAYAPPPPGPAIRSLPKEAYT-------
*: . * .
TH_2386|M.thermoresistible__bu DRTVGILAAVNAATENRRTELLSAGAQLD-LLIDEIDSIVATDP-GPTTV
MSMEG_1143|M.smegmatis_MC2_155 DRTVGVLAAVNAATEGRRTELLTSGAQLN-RLIDEVDSIVATDPSAPTTV
Mflv_0010|M.gilvum_PYR-GCK DDTVGILAAVHAATEDRRTELLTSGAQLN-RMVDELDRIVATEP-GPTTV
Mvan_0959|M.vanbaalenii_PYR-1 DDTVGILAAVNAATEDRRTELLTSGAQLN-SLVDELDRIVATDP-GPTTV
MMAR_3864|M.marinum_M DNSLGILAAIAAATDHRRASLLSGGAQLN-RLLDQLNSIVATDS-EPSTV
MUL_3796|M.ulcerans_Agy99 DNSLGILAAIAAATDHRRASLLSGGAQLN-RLLDQLNSIVATDS-EPSTV
MAV_2388|M.avium_104 DRSVGILAALGAATDHRRVSLLNAGAQLN-RLLDQLNSIVSTDT-GPSTV
MAB_1010c|M.abscessus_ATCC_199 DHSVGILAAVGAATDNRRVKLLTGGAQLN-RLIAQLNDIVVTDT-GPSTV
Mb3906|M.bovis_AF2122/97 PPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQ
Rv3876|M.tuberculosis_H37Rv PPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQ
MLBr_02395|M.leprae_Br4923 ---FWVTRVLAYVIDNIPATVLLG-------IGMLIQTLTKQEACVTDIT
. . : . . .
TH_2386|M.thermoresistible__bu SALIGATRGLQQTAPELLDALHQAVQPMQTLVQ--QRAQLDALIGGALHT
MSMEG_1143|M.smegmatis_MC2_155 STLIEATRGLQQTAPELVDALHTAVRPMQTLVE--QRSQLDSLISAGMNT
Mflv_0010|M.gilvum_PYR-GCK SALVDATRGLQQTAPELVDALHQAVQPMQTLVE--QSAQLTSLVNGGIRT
Mvan_0959|M.vanbaalenii_PYR-1 SALVDATRGLQQTAPELVDALHQAVEPMQTLVE--QSAQLTTFINGGINT
MMAR_3864|M.marinum_M AALIDATRGLQASAPELVEALHQAVEPMKTFAE--TRAQLAALLAGADHT
MUL_3796|M.ulcerans_Agy99 AALIDATRGLQASAPELVEALHQAVEPMKTFAE--TRAQLAALLAGADHT
MAV_2388|M.avium_104 SALLDATRGLAQTAPDLLDALHQAVEPMQTFAE--TRGQLASLLSGADYT
MAB_1010c|M.abscessus_ATCC_199 KALLDATEGLKQTAPELIDSLHQAVKPMQTFVE--KREQLTSLINGGLTT
Mb3906|M.bovis_AF2122/97 ARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQR
Rv3876|M.tuberculosis_H37Rv ARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQR
MLBr_02395|M.leprae_Br4923 QYNVNQYCATQPTGIGMLAFWFAWLMATAYLVWN------------YGYR
. . . :.
TH_2386|M.thermoresistible__bu SATTHTALTNHTDRMVTITTEMTPVIGNLADTSHHWLPAFIKMNGLSDKF
MSMEG_1143|M.smegmatis_MC2_155 LDTTRTALNNHTDRLVKITSELTPVVGNLADTSHHWLPAFVKLNNLSDKF
Mflv_0010|M.gilvum_PYR-GCK SETTRTAFDNHADRLVRITTELTPVVGSLADTSRHWVPAFVKLNELSRKF
Mvan_0959|M.vanbaalenii_PYR-1 VGTTHTALNNHTDRMVRITTELTPVIGNLAQTSHHWVPAFVKLNGLSRKF
MMAR_3864|M.marinum_M IGTAQQSLGNHIDQLIQITTDFTPVLGVLAQQSDNFLPAVIKLDNLATKF
MUL_3796|M.ulcerans_Agy99 IGTAQQSLGNHIDQLIQITTDFTPVLGVLAQQSDNFLPAVIKLDNLATKF
MAV_2388|M.avium_104 VGTTRQSFDNHIDQLIRITADFTPVLGVLAQKSNNFVPAVTKLDNLANQF
MAB_1010c|M.abscessus_ATCC_199 VGTTRQAFDNHTDQLIGITTELTPVIGTFANNASKFQTIFQKATQLGNKW
Mb3906|M.bovis_AF2122/97 NSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSL
Rv3876|M.tuberculosis_H37Rv NSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSL
MLBr_02395|M.leprae_Br4923 QGATGSSIGKTVMKFKVISEATGQPIG-FGMSVVRQLAHFVDAVICCIGF
: : . .
TH_2386|M.thermoresistible__bu FEEVWRPERDIGN-------------------------MRMNLSLTPSYT
MSMEG_1143|M.smegmatis_MC2_155 FDEVWRPERNVGN-------------------------MRMNLSFTPSYT
Mflv_0010|M.gilvum_PYR-GCK FDEVWIHEHDIGN-------------------------MRINLSFTPTYS
Mvan_0959|M.vanbaalenii_PYR-1 FDEVWMHDRDVGN-------------------------MRVNLSFTPTYS
MMAR_3864|M.marinum_M MDEVWMPENNTGN-------------------------MRVNLSFTPSHS
MUL_3796|M.ulcerans_Agy99 MDEVWMPENNTGN-------------------------MRVNLSFTPSHS
MAV_2388|M.avium_104 MEQVWNPQTNLGN-------------------------MRAMLTFTPSST
MAB_1010c|M.abscessus_ATCC_199 FEEPWKPEVDTPN-------------------------MRVNLSMTPGST
Mb3906|M.bovis_AF2122/97 RPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEK
Rv3876|M.tuberculosis_H37Rv RPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEK
MLBr_02395|M.leprae_Br4923 LFPLWDSK------------------------------------------
.
TH_2386|M.thermoresistible__bu YTRADCPRYG------------ELKGPSCYTAPLVVTRPSLPDVLLPQNY
MSMEG_1143|M.smegmatis_MC2_155 YTRADCPQYG------------ELKGPSCFTAPLVVTRPALPDQMLPRNY
Mflv_0010|M.gilvum_PYR-GCK YTRADCPQYA------------GLKGPSCYTAPLVPTRAALPDVLLPQNY
Mvan_0959|M.vanbaalenii_PYR-1 YTRADCPQYG------------ELKGPSCFTAPLVPTRPELPDVLLPQNY
MMAR_3864|M.marinum_M YTRADCPRYG------------ELKGPSCFTAPLVPVRPDLPEVLLPQNY
MUL_3796|M.ulcerans_Agy99 YTRADCPRYG------------ELKGPSCFTAPLVPVRPDLPDVLLPQNY
MAV_2388|M.avium_104 YTRADCPHYG------------ELKGPSCFTAPLIPVRPDLPDVLLPQNY
MAB_1010c|M.abscessus_ATCC_199 YTRADCPRYG------------DLKGPSCFTAPELVVRPDLPETLLPQNY
Mb3906|M.bovis_AF2122/97 YELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRIL
Rv3876|M.tuberculosis_H37Rv YELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRIL
MLBr_02395|M.leprae_Br4923 -------------------------------------RQTLADKIMTTVC
*.:
TH_2386|M.thermoresistible__bu QPPKD-----LAPPPGTIVGENGNLVAVGPPLVNP--NPNLADPNPP---
MSMEG_1143|M.smegmatis_MC2_155 QPPKD-----LAPPPGTVVGENGNLVAVGPPLINP--NPSLADPNPP---
Mflv_0010|M.gilvum_PYR-GCK QPPKD-----LQPPPGTEIGPSGNLIAVGPPLVNP--NPSLADPNPP---
Mvan_0959|M.vanbaalenii_PYR-1 QPPAD-----LKPPPGTEVGPNGNLVAVGPPLVNP--NPDLRDPNPP---
MMAR_3864|M.marinum_M QPPKD-----LAPPPGTAVGPDGNLVALGPPLINP--SPNLTDPNPP---
MUL_3796|M.ulcerans_Agy99 QPPKD-----LAPPPGTAVGPDGNLVALGPPLINP--SPNLTDPNPP---
MAV_2388|M.avium_104 QPPKD-----LAPPPGTVIGPDGNLVAVGPPLINP--TPNLTDPNPP---
MAB_1010c|M.abscessus_ATCC_199 KVPAD-----LQPPRGTVVGPNGNLIAVGPPYVVPPGGPNLTDPNPP---
Mb3906|M.bovis_AF2122/97 ALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLE
Rv3876|M.tuberculosis_H37Rv ALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLE
MLBr_02395|M.leprae_Br4923 LPI-----------------------------------------------
TH_2386|M.thermoresistible__bu -LPPGMF-PAPPVPGTSNPDLVPIPPPPVNLSPLAPVAPNPNKPRPPVPA
MSMEG_1143|M.smegmatis_MC2_155 -LPPWMA-PAPPVPGTANSALPVTPPPGVNQSPLAPVAPKPGSPPPPPPA
Mflv_0010|M.gilvum_PYR-GCK -LPPWMP-PSPPVPLTANPALVPPPQLPAPLSPPAPVAPKPGDPPPRPAA
Mvan_0959|M.vanbaalenii_PYR-1 -LPPWLS-PSPPVPGTANPALVPVPQPPVPLSPPAPVAPKPGDPPPPPAA
MMAR_3864|M.marinum_M -LPAWLT-PSPRVPGTGDPDDAP---------PAPPAPP-------GAAA
MUL_3796|M.ulcerans_Agy99 -LPAWLT-PSPRVPGTGDPDDAP---------PAPPAPP-------GAAA
MAV_2388|M.avium_104 -LAPGIT-PSPPVPGSANPDNPS---------PGAPATPQPQQPWVAPVA
MAB_1010c|M.abscessus_ATCC_199 -LPPWQPNPSPRVPGTADPDLLEPPPPPPPPIPAAPVAPGARDGGGAPIA
Mb3906|M.bovis_AF2122/97 VLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVL
Rv3876|M.tuberculosis_H37Rv VLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVL
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_2386|M.thermoresistible__bu PP-----PAP------------------------GG--------------
MSMEG_1143|M.smegmatis_MC2_155 PG-----PLPAEAAPA----------------SFGGNVGPVGSEQERVTL
Mflv_0010|M.gilvum_PYR-GCK PAPAAPAPAPAAPAPAPAAPGPGSAEAPFAPASFGGNVGPVGSQQEQRQL
Mvan_0959|M.vanbaalenii_PYR-1 PPVSGPAPLPAEAAPA----------------GYGGNVGPVGSRHELDQL
MMAR_3864|M.marinum_M PSA------------------------------FGGNVGPVGSRQERDAL
MUL_3796|M.ulcerans_Agy99 PSA------------------------------FGGNVGPVGSRQEGDAL
MAV_2388|M.avium_104 PKAPWIPQSSFRPS-------------------FGGNVGPVGSQYERTML
MAB_1010c|M.abscessus_ATCC_199 PAS------------------------------FGGTVGPVGSQVERAQL
Mb3906|M.bovis_AF2122/97 STVSGVVVVASVSIDG------AQQASVALDWLRNNGYQDLASRACVVIN
Rv3876|M.tuberculosis_H37Rv STVSGVVVVASVSIDG------AQQASVALDWLRNNGYQDLASRACVVIN
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_2386|M.thermoresistible__bu --------------------------------------------------
MSMEG_1143|M.smegmatis_MC2_155 SVITGQPASTATQLL-------------------------------LGPV
Mflv_0010|M.gilvum_PYR-GCK SLITGRHATPATQLL-------------------------------LGPL
Mvan_0959|M.vanbaalenii_PYR-1 GYITGQPATVATQLL-------------------------------LGPV
MMAR_3864|M.marinum_M ALITGRPATVATELL-------------------------------LGPL
MUL_3796|M.ulcerans_Agy99 ALITGRPATVATELL-------------------------------LGPL
MAV_2388|M.avium_104 GAITGGPASEATQLL-------------------------------LGPV
MAB_1010c|M.abscessus_ATCC_199 SVITDKPASSATQLL-------------------------------LGPV
Mb3906|M.bovis_AF2122/97 HIMPGEPNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPI
Rv3876|M.tuberculosis_H37Rv HIMPGEPNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPI
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_2386|M.thermoresistible__bu --------------GEEPR-----
MSMEG_1143|M.smegmatis_MC2_155 ARGTTVSLAEP-TAGEEPR-----
Mflv_0010|M.gilvum_PYR-GCK ARGTTVS------IDGEP------
Mvan_0959|M.vanbaalenii_PYR-1 ARGTTVS------EGVR-------
MMAR_3864|M.marinum_M ARGTVVSLRNS-GAGGEPR-----
MUL_3796|M.ulcerans_Agy99 ARGTVVSLRNS-GAGGEPR-----
MAV_2388|M.avium_104 ARGTTVSLAHPPGPSPAPRPGEGK
MAB_1010c|M.abscessus_ATCC_199 VRGTTVSLAKE----GSP------
Mb3906|M.bovis_AF2122/97 YKRKVLELAAALSDDFERAGRR--
Rv3876|M.tuberculosis_H37Rv YKRKVLELAAALSDDFERAGRR--
MLBr_02395|M.leprae_Br4923 ------------------------