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ARTEGDTWDIVTSVGATALVVSAMRAIEARKPEPLARDDYAQHFVAATKAEAPLFSELLEDPEAAQAPDI QLFSSYLGARTKYFDEFFLTAGNAGVRQAVILAAGLDVRGYRLPWAAGTTVYELDLPKVLEFKKQVLDEH NARATATVLDLHVDLRDDWPTVLKAAGFDPAQPTAWLAEGLLPFLPGAAQDLLFERIADLSAPGSRVAVE DFGAPGNQADRMSNAMQNEEGALQRIFKSIVEEDAPPSSLWFGDEREDPARWLTGHGWTVEATTAGELLK RYNRVPLAGEHELTDAMGQSRYFTAVLGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4587c | - | - | 100% (310) | hypothetical protein MAB_4587c |
| M. abscessus ATCC 19977 | MAB_4584c | - | 3e-72 | 49.52% (313) | hypothetical protein MAB_4584c |
| M. abscessus ATCC 19977 | MAB_4586c | - | 1e-69 | 48.21% (307) | hypothetical protein MAB_4586c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3793c | - | 8e-64 | 44.88% (303) | hypothetical protein Mb3793c |
| M. gilvum PYR-GCK | Mflv_0743 | - | 3e-60 | 42.44% (311) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv3767c | - | 9e-64 | 44.88% (303) | hypothetical protein Rv3767c |
| M. leprae Br4923 | MLBr_02020 | - | 9e-63 | 44.77% (306) | hypothetical protein MLBr_02020 |
| M. marinum M | MMAR_0955 | - | 7e-65 | 46.18% (301) | hypothetical protein MMAR_0955 |
| M. avium 104 | MAV_4558 | - | 5e-70 | 46.54% (318) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_0614 | - | 1e-65 | 46.13% (297) | methyltransferase |
| M. thermoresistible (build 8) | TH_2759 | - | 5e-63 | 46.92% (292) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_0706 | - | 7e-64 | 45.15% (299) | hypothetical protein MUL_0706 |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 3e-63 | 45.27% (296) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3793c|M.bovis_AF2122/97 -----------MPRTDNDSWAITESVGATALGVAAARAAETESDNPLIND
Rv3767c|M.tuberculosis_H37Rv -----------MPRTDNDSWAITESVGATALGVAAARAAETESDNPLIND
MMAR_0955|M.marinum_M -----------MARTEDDSWEITESVGATALGVASARAAETRSQHPLISD
MUL_0706|M.ulcerans_Agy99 -----------MARTEDDSWEITESVGATALGVASARAAETRSQHPLISD
MAV_4558|M.avium_104 -----------MPRTDDDSWEITESVGATALGVAAARAAETESENPLISD
Mflv_0743|M.gilvum_PYR-GCK ---------MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALIND
Mvan_0104|M.vanbaalenii_PYR-1 ---------MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDD
TH_2759|M.thermoresistible__bu MVMMFDVTEAASARSEGDSWDITESVGATALGVAAERALETSQPDPLIRD
MSMEG_0614|M.smegmatis_MC2_155 ------------MRTDNDQWDITISVGQTALFVAASRALEARKPHPLAVD
MAB_4587c|M.abscessus_ATCC_199 -----------MARTEGDTWDIVTSVGATALVVSAMRAIEARKPEPLARD
MLBr_02020|M.leprae_Br4923 --MMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVRD
*::.* * *. *** **: *:. ** .: ..* *
Mb3793c|M.bovis_AF2122/97 PFARIFVDAAGDGIWSMYTNRTLLAGATDLDPDLRAPIQQMIDFMAARTA
Rv3767c|M.tuberculosis_H37Rv PFARIFVDAAGDGIWSMYTNRTLLAGATDLDPDLRAPIQQMIDFMAARTA
MMAR_0955|M.marinum_M PFAQVFLDAVGDGVWNWHSAPQLPAELLEIEPDLPLQMEAMVSYMASRTA
MUL_0706|M.ulcerans_Agy99 PFAQVFLDAVGDGVWNWHSAPQLPAELLEIEPDLPLQMEAMVSYMASRTA
MAV_4558|M.avium_104 PFARVFLDAAGDGMWNWFAAPNLPAQIAEAEPDLKPRMQGMVDYMAARTA
Mflv_0743|M.gilvum_PYR-GCK PYAKVLVEGAGAGAWRFIADEDLVAKASESDTEVGALFEHMKNYQAVRTH
Mvan_0104|M.vanbaalenii_PYR-1 PYAKILVAGAGNGAWQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRTH
TH_2759|M.thermoresistible__bu EYAFLLVSAAGP-PWTQLASSDLSWLG--DDETARRMHLMSRDYQAVRTH
MSMEG_0614|M.smegmatis_MC2_155 HYAEVFCRAAGG---DWVAAVEGTDPEHPLQTEFG---VDFVNFQGARTK
MAB_4587c|M.abscessus_ATCC_199 DYAQHFVAATKA------EAPLFSELLEDPEAAQAPDIQLFSSYLGARTK
MLBr_02020|M.leprae_Br4923 EYAKYFITASRD--------PYLMNLLANPGTSLN--ETAFPRLYGVQTR
:* : . . :*
Mb3793c|M.bovis_AF2122/97 FFDEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEF
Rv3767c|M.tuberculosis_H37Rv FFDEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEF
MMAR_0955|M.marinum_M FFDEFFLDATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVLEF
MUL_0706|M.ulcerans_Agy99 FFDEFFLDATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVLEF
MAV_4558|M.avium_104 FFDNFFLAATRAGVRQVVILAAGLDSRAWRLPFEDGTTVYELDQPRVLEF
Mflv_0743|M.gilvum_PYR-GCK FFDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDY
Mvan_0104|M.vanbaalenii_PYR-1 FFDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAY
TH_2759|M.thermoresistible__bu YFDRYFAAAARAGIRQIVLLAAGLDSRAYRLDWPAGTVVYELDQPRVLDF
MSMEG_0614|M.smegmatis_MC2_155 YFDDYFRRVADAGVRQVVLLAAGLDSRAYRLPWADGTVVYELDVPKVLEF
MAB_4587c|M.abscessus_ATCC_199 YFDEFFLTAGNAGVRQAVILAAGLDVRGYRLPWAAGTTVYELDLPKVLEF
MLBr_02020|M.leprae_Br4923 FFDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPKVLEF
:** :* . :*: * *::*:*** *.:** : *:.*:*:* * ** :
Mb3793c|M.bovis_AF2122/97 KSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLV
Rv3767c|M.tuberculosis_H37Rv KSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLV
MMAR_0955|M.marinum_M KAATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVPSVWSAEGLM
MUL_0706|M.ulcerans_Agy99 KAATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVSSVWSAEGLM
MAV_4558|M.avium_104 KATTLAEYGARPTCHLVSVPVDLRHDWPAALRQAGFDAHAPSAWSAEGLL
Mflv_0743|M.gilvum_PYR-GCK KSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLL
Mvan_0104|M.vanbaalenii_PYR-1 KSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLL
TH_2759|M.thermoresistible__bu KNRTLQAHGAVAKADRRTVAVDLRDDWPAALRHAGFDSAAPTAWLAEGLL
MSMEG_0614|M.smegmatis_MC2_155 KREVLRRHGATPTAERREVPVDLRDDWPAALRANGFDASQPSAWIAEGLL
MAB_4587c|M.abscessus_ATCC_199 KKQVLDEHNARATATVLDLHVDLRDDWPTVLKAAGFDPAQPTAWLAEGLL
MLBr_02020|M.leprae_Br4923 KARVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSVEGLL
* .* .. . . : *** *** .* ***. . .* .***:
Mb3793c|M.bovis_AF2122/97 RYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRM
Rv3767c|M.tuberculosis_H37Rv RYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRM
MMAR_0955|M.marinum_M PYLPAVAQDLLFERVQGLTVRASRIAVEALGPKFLDPQVRANRSARMERI
MUL_0706|M.ulcerans_Agy99 PYLPAVAQDLLFERVQGLTVRASRIAVEALGPKFLDPQVRANRSARIERI
MAV_4558|M.avium_104 PFLPAAAQQLLFERVQTLAAPGSRIAVEAPGPDFLDEAARERQRQTMQRV
Mflv_0743|M.gilvum_PYR-GCK MYLPADAQDRLFAQITELSAPGSQVAAESMG---VHAP----DRRERMRE
Mvan_0104|M.vanbaalenii_PYR-1 MYLPADAQDRLFAQITELSAPGSRVAAESMG---IHAQ----DRRERMRE
TH_2759|M.thermoresistible__bu CYLPADAQDRLFERITALSAPGSWLAVEAFH---HDPQRATERRRAEWRD
MSMEG_0614|M.smegmatis_MC2_155 IYLPADAQELLFAGIDALSAPGSFVAIEESAP------------MPMDVF
MAB_4587c|M.abscessus_ATCC_199 PFLPGAAQDLLFERIADLSAPGSRVAVEDFGAPGNQADRMSNAMQNEEGA
MLBr_02020|M.leprae_Br4923 PYLTNDAQSALFTRIGELCAPGSRIAVGALG---------SRLDRKQLAA
:*. **. ** : * .* :*
Mb3793c|M.bovis_AF2122/97 RAAAAKLVET-EISDVDDLWYAE-QRTAVAEWLRERGWDVSTAT-LPELL
Rv3767c|M.tuberculosis_H37Rv RAAAAKLVET-EISDVDDLWYAE-QRTAVAEWLRERGWDVSTAT-LPELL
MMAR_0955|M.marinum_M RAVMAHVEPQREIPRTDELWYFE-EREDVGDWFRRHDWDVTVTP-SGELM
MUL_0706|M.ulcerans_Agy99 RAVMAHVEPQREIPRTDELWYFE-EREDVGDWFRRHDWDVTVTP-SGELM
MAV_4558|M.avium_104 RDLMADLEPDRDIPDVQDLWYFE-EREDVGDWLGRHGWDVTVTP-APELM
Mflv_0743|M.gilvum_PYR-GCK RFASIASQIDIEPMDITELTYEDPDRAEVAEWLAAHGWTAQAVP-SQDAM
Mvan_0104|M.vanbaalenii_PYR-1 RFASITAQFDVEPMDITELTYEDPDRADVAQWLTAHGWRAEAVP-SQDEM
TH_2759|M.thermoresistible__bu RTARMKAALDLN-LDFEALTYDDPDRADAGEWLAAHGWHPDSVP-GTEEM
MSMEG_0614|M.smegmatis_MC2_155 EVKRAEALASGDPNSFFALVFNE-QCAPGEQWFSERGWTASTTT-LNECL
MAB_4587c|M.abscessus_ATCC_199 LQRIFKSIVEEDAPPSS-LWFGD-EREDPARWLTGHGWTVEATT-AGELL
MLBr_02020|M.leprae_Br4923 LEATHPGVNISGDVDFSALTYEP--KTDSAQWLAAHGWAVEPVRNTLELQ
* : *: :.* . :
Mb3793c|M.bovis_AF2122/97 ARYGRS---IPHSGEDSIPPNLFVSAQRATS-----
Rv3767c|M.tuberculosis_H37Rv ARYGRS---IPHSGEDSIPPNLFVSAQRATS-----
MMAR_0955|M.marinum_M AGYGRA---AAAQVEDRVPTNLFVAAQRK-------
MUL_0706|M.ulcerans_Agy99 AGYGRA---AAAQVEDRVPTNLFVAAQRN-------
MAV_4558|M.avium_104 ARYDRR---PPHDIEDATPQTRFVAAQRTERTRPDR
Mflv_0743|M.gilvum_PYR-GCK RRLDRY---VEVADSDGQSFSTFTTGTKL-------
Mvan_0104|M.vanbaalenii_PYR-1 RRLHRL---VEIADGDDQSFSTFTTAVKR-------
TH_2759|M.thermoresistible__bu ARMGRP---VPADLLDVAVPSTLLRAHLNGASR---
MSMEG_0614|M.smegmatis_MC2_155 HEVGRP---APAPDSEAAQMTGSISLMWARKG----
MAB_4587c|M.abscessus_ATCC_199 KRYNRVPLAGEHELTDAMGQSRYFTAVLGA------
MLBr_02020|M.leprae_Br4923 TSYGMTP-PDVDVQMDSFMHSQYITATR--------
: .