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INTLATTIVDAVKMGHRQRFWLSGMALLATLLVACAYLMVGALRARAFASTYEVSIELPESGGLIPEQDV ALRGMRVGRVDSVTPSPRGPIARIHIESGVKIPVGTPVRVSGLSPAGEQYVDFAPVTTAGPYLSNGSVIT RGQATVPVSLSRLLADADGALAQADTKKLEIIKKELHLSRDAPRKMTDIIDGGVFLLSTLDSVLPETVSI LKKSRVTLSSFAEMNNGLAVTTQGLNRSLNGVARMDNGFRTLIDRVPGPLATTDAVIADNSDNMAQLLGN LTTVAQLSYVRVPALNALFPTYRGSVIDAVANTFHDNGVWAIADIYPRYTCDYGYPRTAVSAADYPEPFL YAGYCRDDDPAVLVRGAKNAPRPADDDTASPPSGADLGKVADPTPKGRFTIPTPYGGPTLPIEPPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4563c | - | - | 100% (417) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_1005c | - | e-150 | 61.54% (416) | putative MCE family protein |
| M. abscessus ATCC 19977 | MAB_4511c | - | e-148 | 62.44% (418) | putative Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0610 | mce2F | 1e-22 | 26.72% (363) | MCE-family protein MCE2F |
| M. gilvum PYR-GCK | Mflv_0005 | - | 1e-146 | 60.43% (417) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv0594 | mce2F | 1e-22 | 26.72% (363) | MCE-family protein MCE2F |
| M. leprae Br4923 | MLBr_02594 | mce1F | 1e-20 | 23.08% (364) | putative secreted protein |
| M. marinum M | MMAR_3869 | mce5F | 1e-148 | 62.02% (416) | Mce family protein Mce5F |
| M. avium 104 | MAV_0107 | - | 1e-150 | 61.54% (416) | mce related protein |
| M. smegmatis MC2 155 | MSMEG_1148 | - | 1e-141 | 58.00% (419) | mce related protein |
| M. thermoresistible (build 8) | TH_2636 | - | 9e-96 | 56.07% (321) | PUTATIVE mce related protein |
| M. ulcerans Agy99 | MUL_3801 | mce5F | 1e-148 | 62.02% (416) | Mce family protein Mce5F |
| M. vanbaalenii PYR-1 | Mvan_0964 | - | 1e-145 | 59.23% (417) | hypothetical protein Mvan_0964 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0005|M.gilvum_PYR-GCK MINALADSVVRVVRTVHRGRAWLSAGALVFILVVAAAYLFVGALQVNPLA
Mvan_0964|M.vanbaalenii_PYR-1 MIGSVADAVVGVARFGYRRRAWLSTAALIMTLVVASAYLFFGALQVNPLA
MSMEG_1148|M.smegmatis_MC2_155 MINAVADRIVGLVRFGYRKRSWLSALGLVMTLVVATAYLFFGALQVNPLD
TH_2636|M.thermoresistible__bu MIGAVADRIVALVRFGHRRRATLSTIGLILTLVVATAYLLFGALQVNPFA
MMAR_3869|M.marinum_M MITPIANAVVRVVRAGHRQQTWLSVAGLVLTLVVAAAYLLVGALRLTPFA
MUL_3801|M.ulcerans_Agy99 MITPIANAVVRVVRAGHRQQTWLSVAGLVLTLVVAAAYLLVGALRLTPFA
MAV_0107|M.avium_104 MIDTLGRLVVGVVKAGHRQRTWLSGLALLVTLVVGGAYLALGALRVNPLE
MAB_4563c|M.abscessus_ATCC_199 MINTLATTIVDAVKMGHRQRFWLSGMALLATLLVACAYLMVGALRARAFA
Mb0610|M.bovis_AF2122/97 ----------MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSLVG---I
Rv0594|M.tuberculosis_H37Rv ----------MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSLVG---I
MLBr_02594|M.leprae_Br4923 ----------MLTPLIRRQLVLFAILTVISLTVLGVYYLQIPSLVG---I
. :: :: ::. :* . :*
Mflv_0005|M.gilvum_PYR-GCK KSYRVTVQLPESAGLLPNQNVTLRGVPIGRVERLDITPAGVDAVVSMDSS
Mvan_0964|M.vanbaalenii_PYR-1 SSYRVTVELPESAGLLPNQNVTMRGVPIGRVERLDITPAGVNAVVSVDSS
MSMEG_1148|M.smegmatis_MC2_155 SDYGLTVQLPESAGLLPDQDVTLRGVPIGRVERLDITPSGVNAIVKVKST
TH_2636|M.thermoresistible__bu SSYQVTVALPESGGLLPNQAVTLRGVPVGRVERLDITPEGVNAVVDIDSA
MMAR_3869|M.marinum_M SSYRVTVSLPESGGLLPNQDVALRGVRIGRIESLHITESGVDAIASITSQ
MUL_3801|M.ulcerans_Agy99 SSYRVTVSLPESGGLLPNQDVALRGVRIGRIESLHLTESGVDAIASITSQ
MAV_0107|M.avium_104 STYQVTIRLPESGGLLANQDVSVRGIRVGRITSLRPIPSGVEVVANINAH
MAB_4563c|M.abscessus_ATCC_199 STYEVSIELPESGGLIPEQDVALRGMRVGRVDSVTPSPRGPIARIHIESG
Mb0610|M.bovis_AF2122/97 GRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNG
Rv0594|M.tuberculosis_H37Rv GRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNG
MLBr_02594|M.leprae_Br4923 GRYSLKAELSATGGLYPTANVTYRGIAIGKVTDVEPTATGAEATMSIDSR
* : *. :.** *: **: :*:: : * . :
Mflv_0005|M.gilvum_PYR-GCK VAVPMSSAVRVSGLSPAGEQYIDFV--ADSDAGPYLENGSVIAQDNTTVP
Mvan_0964|M.vanbaalenii_PYR-1 AAVPVASSVRVSGLSPAGEQYIDFV--ADSGDGPYLADGAVVSQDNTVVP
MSMEG_1148|M.smegmatis_MC2_155 VRIPEASDVRVSGLSPAGEQYIDFIDVPAEDSSRFLADGAVIRQGQATVP
TH_2636|M.thermoresistible__bu VKIPDSSAVRVSGLSPAGEQYIDFI--PEEDTGRYLADGAHIGQGTATVP
MMAR_3869|M.marinum_M VKIPASSAVHVSALSPAGEQFLDFE--PESDTGPYLGEGAVIGVDQARVP
MUL_3801|M.ulcerans_Agy99 VKIPASSTVHVSALSPAGEQFLDFE--PESDTGPYLSEGAVIGVDQARVP
MAV_0107|M.avium_104 TKIPASSPVRVSGLSPAGEQYIDFE--PTSNTGPFLSNGSVIGPQHTTTP
MAB_4563c|M.abscessus_ATCC_199 VKIPVGTPVRVSGLSPAGEQYVDFA--PVTTAGPYLSNGSVITRGQATVP
Mb0610|M.bovis_AF2122/97 YQIPTDASANVHSVSAVGEQFVDLVS--TRTSGPYLRHGQTIT--TTTVP
Rv0594|M.tuberculosis_H37Rv YQIPTDASANVHSVSAVGEQFVDLVS--TRTSGPYLRHGQTIT--TTTVP
MLBr_02594|M.leprae_Br4923 YKIPIDSAANVHSVSAVGEQYLDLVS--SGNPGKYLAPGQTIT--KSKIP
:* : ..* .:*..***::*: . :* * : : *
Mflv_0005|M.gilvum_PYR-GCK VSLADLLANADGALSQVDPGKLEVIKHELSMTEAGP-QKLADIIDGGTFL
Mvan_0964|M.vanbaalenii_PYR-1 VSLADLLANADGALAQADPAKLELIKRELSMSEAGP-QKLADIIDGGTFL
MSMEG_1148|M.smegmatis_MC2_155 VSLADLLADADGALGQVDTAKIELIKRELSLTDAGP-QKLADIVDGGTFL
TH_2636|M.thermoresistible__bu VPLAELLADADGALAQADVEKLEIIRRELSLSPAGP-QKLKDIVDGGTFL
MMAR_3869|M.marinum_M VSLAQLLGDANGLLAQIDPHQVELIKKELSLSQAGP-KKLAAIVDGGTFL
MUL_3801|M.ulcerans_Agy99 VSLAQLLGDANGLRAQIDPHQVELIKKVLSLSQAGP-KKLAAIVDGGTFL
MAV_0107|M.avium_104 IPLSQVLADADGLIAQTDPKKLEIVKRELSLSNQGP-QKLTDIIDGSTFL
MAB_4563c|M.abscessus_ATCC_199 VSLSRLLADADGALAQADTKKLEIIKKELHLSRDAP-RKMTDIIDGGVFL
Mb0610|M.bovis_AF2122/97 SQIGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAI
Rv0594|M.tuberculosis_H37Rv SQIGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAI
MLBr_02594|M.leprae_Br4923 IEIGPALDSVNRGLAALPKEKIGSLLDETAQAVGGLGPALQRLVSSTQAI
:. * .: . :: : : . : ::.. :
Mflv_0005|M.gilvum_PYR-GCK LTTLDSVLPETSSMLRTSRVVFTLAADKNAGIEVASDNLAQTFDGVNRMR
Mvan_0964|M.vanbaalenii_PYR-1 LTTLDSVLPETSSMLRTSRVVLTLAADKNAGIEVASQNLDQVFDGVNRMR
MSMEG_1148|M.smegmatis_MC2_155 LSTLDSVLPETSSLLRTSRVVFTLMADKNPGISVASDNLTETFTGMDKMR
TH_2636|M.thermoresistible__bu LSTLDSVLPETSSLLRTSRVVFTLIDDKNAGIDVAADNLADTFDGVNRMR
MMAR_3869|M.marinum_M LSTLDSVLPETTSIIRTGRVVLNLVADKNAGLAATAVALDRTLAGVARMQ
MUL_3801|M.ulcerans_Agy99 LSTLDSVLPETTSIIRTSRVVLNLIADKNAGLAATAVTLDRTLAGVARMQ
MAV_0107|M.avium_104 LSTMDPVLPQTVSMLKTSRVVLMTLSDKNAGLSVAARNVGDLMAGVNKMD
MAB_4563c|M.abscessus_ATCC_199 LSTLDSVLPETVSILKKSRVTLSSFAEMNNGLAVTTQGLNRSLNGVARMD
Mb0610|M.bovis_AF2122/97 AHDVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTD
Rv0594|M.tuberculosis_H37Rv AHDVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTD
MLBr_02594|M.leprae_Br4923 VDAFKTNITDVNDIIQNSGPILDSQVKSDNAIERWVHNLNVLAAQSARQD
. : : .::. . : . . : : :
Mflv_0005|M.gilvum_PYR-GCK DGFRRLTDRAPGTLNSVDNLFADNSDTMVQLLGNLTTTSQLLYLRVPALH
Mvan_0964|M.vanbaalenii_PYR-1 QGFRTLTEQTPETLAEVDNLFADNSETMVQLLGSLTSTSQLLYLRVPALN
MSMEG_1148|M.smegmatis_MC2_155 EGYRRLTNQTPETLAAVDNLFVDNSDTMVQLLGNLTTASRLLYLRVPALN
TH_2636|M.thermoresistible__bu EGYRRLTDQTPEVLAHVDNLFADNSDTMVQLLGNLTTTSRLLYLRVPALN
MMAR_3869|M.marinum_M GGYRSLTERTPHTLAAIDHLFADNSDTMVQLLGSMATAAQLLYLRVPALN
MUL_3801|M.ulcerans_Agy99 GGYRSLTERTPHTLAAIDHLFADNSDTMVQLLGSMATAAQLLYLRVPALN
MAV_0107|M.avium_104 RGYRRLVDQTPHALSTVDNLFDDNSDTMVGLLANLVTTARVVYLRVPALN
MAB_4563c|M.abscessus_ATCC_199 NGFRTLIDRVPGPLATTDAVIADNSDNMAQLLGNLTTVAQLSYVRVPALN
Mb0610|M.bovis_AF2122/97 PAVRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVE
Rv0594|M.tuberculosis_H37Rv PAVRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVE
MLBr_02594|M.leprae_Br4923 QHLKSILSQAAPTADEVNTVFSDVRDSLPQTLANFEILIDMLKRYHHGVE
: : ... : : * :.: *..: : .:.
Mflv_0005|M.gilvum_PYR-GCK --ALFPDYRTSVLDAIGSAMHDNG-----LWATGEIYPRYTCDYGTPRRP
Mvan_0964|M.vanbaalenii_PYR-1 --ALFPAHRTSVLDAIGSIMHDNG-----LWATGDIYPRYSCDYGTPRLP
MSMEG_1148|M.smegmatis_MC2_155 --ALFPSYRTSVLDALGTAIHDGG-----LWGTAEPYPRYTCDYGTPKLP
TH_2636|M.thermoresistible__bu --ALFPSHRTSVLDALGAAMHDGG-----LWGXXXP-PTICCNARRTRPP
MMAR_3869|M.marinum_M --ALFPDYRGSVLDALASAFHDHG-----VWATAELYPRYTCDYGTPSYL
MUL_3801|M.ulcerans_Agy99 --ALFPDYRGSVLDALASAFHDHG-----VWATAELYPRYTCDYGTPSYL
MAV_0107|M.avium_104 --AVFPNYRGSTLEALMTTMHEHG-----LWATADIYPRYTCDYGTPRRP
MAB_4563c|M.abscessus_ATCC_199 --ALFPTYRGSVIDAVANTFHDNG-----VWAIADIYPRYTCDYGYPRTA
Mb0610|M.bovis_AF2122/97 QALVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQPPPCLTGFLPASEWR
Rv0594|M.tuberculosis_H37Rv QALVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQPPPCLTGFLPASEWR
MLBr_02594|M.leprae_Br4923 QMLVFLPQGASIAQTASATFPNMAALDLA-LSINQPPPCLTGFIPAAEWR
:* : :: : . . * .
Mflv_0005|M.gilvum_PYR-GCK PSSADFPEPFMYN-YCRDDHPG--VLVRGAKN------------APRPAG
Mvan_0964|M.vanbaalenii_PYR-1 PSSADYPEAFMYT-YCRDDHPG--VLVRGAKN------------APRPAG
MSMEG_1148|M.smegmatis_MC2_155 PSSADFPEPFMYT-YCRDVHPG--VLVRGAKN------------APRPAD
TH_2636|M.thermoresistible__bu PI------------------------------------------------
MMAR_3869|M.marinum_M PSAADYPEPFMYT-YCRDDDPA--VSIRGAKN------------APRPGG
MUL_3801|M.ulcerans_Agy99 PSAADYPEPFMYT-YCRDDDPA--VSIRGAKN------------APRPGG
MAV_0107|M.avium_104 SSSADYPEPFLYT-YCRDDDPQ--VLVRGAKN------------APRPGG
MAB_4563c|M.abscessus_ATCC_199 VSAADYPEPFLYAGYCRDDDPA--VLVRGAKN------------APRPAD
Mb0610|M.bovis_AF2122/97 SPADTSTAPLPKGTYCRIPMDA-SNVVRGARNNPCVDVPGKRAATPRECR
Rv0594|M.tuberculosis_H37Rv SPADTSTAPLPKGTYCRIPMDA-SNVVRGARNNPCVDVPGKRAATPRECR
MLBr_02594|M.leprae_Br4923 SPADTSLQPLPVGTYCKIPMDTPANSVRGSRNIPCVDVPGKRAASPRECR
Mflv_0005|M.gilvum_PYR-GCK DDTAGPPPGADLGR------QTDPTPRGRYTIPTPYG-------------
Mvan_0964|M.vanbaalenii_PYR-1 DDTAGPPAGADLGR------TTDPTPKGRYTIPTPYG-------------
MSMEG_1148|M.smegmatis_MC2_155 DDTAGPPPGADLGR------QTDPTPRGRYTIPTPYG-------------
TH_2636|M.thermoresistible__bu --------------------------------------------------
MMAR_3869|M.marinum_M DDTAGPPPGADLGR------RTDPTPRGRFTIPTPYG-------------
MUL_3801|M.ulcerans_Agy99 DDTAGPPPGADLGR------RTDPTPRGRFTIPTPYG-------------
MAV_0107|M.avium_104 DDTAGPPPGADLGQ------TTDPTPKGRFTIPTPYG-------------
MAB_4563c|M.abscessus_ATCC_199 DDTASPPSGADLGK------VADPTPKGRFTIPTPYG-------------
Mb0610|M.bovis_AF2122/97 SNEAYVPGGTNPWYGDPNQMLSCPAPAARCDQPVKPGQVIPAPSVNNGIN
Rv0594|M.tuberculosis_H37Rv SNEAYVPGGTNPWYGDPNQMLSCPAPAARCDQPVKPGQVIPAPSVNNGIN
MLBr_02594|M.leprae_Br4923 DSKPYVPLGTNPWFGDPNQLLTCPAPGARCDQPVKPGLVIPAPTVDNGLN
Mflv_0005|M.gilvum_PYR-GCK ---GPTLPIEPPR-------------------------------------
Mvan_0964|M.vanbaalenii_PYR-1 ---GPTLPIEPPR-------------------------------------
MSMEG_1148|M.smegmatis_MC2_155 ---GPTLPIEPPR-------------------------------------
TH_2636|M.thermoresistible__bu --------------------------------------------------
MMAR_3869|M.marinum_M ---GPVLPIEPPH-------------------------------------
MUL_3801|M.ulcerans_Agy99 ---GPVLPIEPPH-------------------------------------
MAV_0107|M.avium_104 ---GPVLPIEPPH-------------------------------------
MAB_4563c|M.abscessus_ATCC_199 ---GPTLPIEPPR-------------------------------------
Mb0610|M.bovis_AF2122/97 PLPADQLPGTPPPVNDPLQRPGSGTVQCNGQQPNPCVYTPSTFPTTIYDV
Rv0594|M.tuberculosis_H37Rv PLPADQLPGTPPPVNDPLQRPGSGTVQCNGQQPNPCVYTPSTFPTTIYDV
MLBr_02594|M.leprae_Br4923 PAPADRLPGTPPPVSDPLSQPRSGSVQCNGQQPNTCVYTPSGPPSAVYSP
Mflv_0005|M.gilvum_PYR-GCK ----------------------------------
Mvan_0964|M.vanbaalenii_PYR-1 ----------------------------------
MSMEG_1148|M.smegmatis_MC2_155 ----------------------------------
TH_2636|M.thermoresistible__bu ----------------------------------
MMAR_3869|M.marinum_M ----------------------------------
MUL_3801|M.ulcerans_Agy99 ----------------------------------
MAV_0107|M.avium_104 ----------------------------------
MAB_4563c|M.abscessus_ATCC_199 ----------------------------------
Mb0610|M.bovis_AF2122/97 QSGKVVAPDGVVYSVEASTHAGADGWKVMLAPTG
Rv0594|M.tuberculosis_H37Rv QSGKVVAPDGVVYSVEASTHAGADGWKVMLAPTG
MLBr_02594|M.leprae_Br4923 QSGELVGPDGVAYAVENSTKTGDDGWKEMLAPAG