For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_0754c (-)

annotation: fatty acid desaturase
coordinates: 755542 - 756549
length: 335

SQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKALGGQDWDPEQSKLSEVAKIAMI
TNLLTEDNLPSYHREIAMNFTMDGPWGTWVNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRVEQMTRG
FSPGQNRQGGDELFAESLFDSVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDENLHMIFYRNLV
EAGMHIAPDQALKSIHKVLDNFKMPGYTIPGFRRNAVTIATGGVYDPQSHLDEVVMPVLRKWRIFERDDI
SSEGEWYREDLDRIIGDLKKTSADFEEVKAKYLERQAKRAERQAAKAAREAVSV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0754c--100% (335)fatty acid desaturase
M. abscessus ATCC 19977MAB_2550c-e-17892.00% (325) fatty acid desaturase
M. abscessus ATCC 19977MAB_3354-e-17789.30% (327) acyl-

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0847cdesA11e-13267.39% (322) acyl-
M. gilvum PYR-GCKMflv_1668-1e-14272.22% (324) fatty acid desaturase, type 2
M. tuberculosis H37RvRv0824cdesA11e-13267.39% (322) acyl-
M. leprae Br4923MLBr_02185desA11e-13367.49% (323) acyl-
M. marinum MMMAR_3704desA1_11e-13768.73% (323) acyl-
M. avium 104MAV_0772-1e-13568.94% (322) Fatty acid desaturase
M. smegmatis MC2 155MSMEG_5773-1e-14171.87% (327) fatty acid desaturase
M. thermoresistible (build 8)TH_1577-1e-13870.09% (331) fatty acid desaturase
M. ulcerans Agy99MUL_3646desA1_11e-13868.73% (323) acyl-
M. vanbaalenii PYR-1Mvan_5085-1e-14473.46% (324) fatty acid desaturase, type 2

CLUSTAL 2.0.9 multiple sequence alignment


Mb0847c|M.bovis_AF2122/97           -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
Rv0824c|M.tuberculosis_H37Rv        -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
MAV_0772|M.avium_104                -MSAELTNLQLLQELEPFVEKYLNRHESMHKNWNPHDYIPWSDGKNFYAL
MLBr_02185|M.leprae_Br4923          -MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYAL
MMAR_3704|M.marinum_M               -MSKEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
MUL_3646|M.ulcerans_Agy99           -MSKEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
TH_1577|M.thermoresistible__bu      -MHENLTDLHLLRELEPVVEKLLNRHLSMSKDWNPHDYIPWSDGKNYYAL
MSMEG_5773|M.smegmatis_MC2_155      MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYAL
Mflv_1668|M.gilvum_PYR-GCK          -MSKDLTDLQLLTELEPVVEPLVNRHMRMKKDWNPHDYIPWSDGKNYYAL
Mvan_5085|M.vanbaalenii_PYR-1       -MSKDLTDLQLLTELEPVVEPLINRHMRMTKDWNPHDYIPWSDGKNYYAL
MAB_0754c|M.abscessus_ATCC_199      MSQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKAL
                                        . *:*.** **:*.**  :.**  : * ******:***:***: **

Mb0847c|M.bovis_AF2122/97           GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Rv0824c|M.tuberculosis_H37Rv        GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MAV_0772|M.avium_104                GGQDWEPGQSKLSDVAQVAMVQNLMTEDNLPSYHREIAMNFGMDGPWGQW
MLBr_02185|M.leprae_Br4923          GGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQW
MMAR_3704|M.marinum_M               DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
MUL_3646|M.ulcerans_Agy99           DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
TH_1577|M.thermoresistible__bu      GGQDWYPEEAKLSEVAQTAMVQNLLTEDNLPAYHREIAMNLGMDGAWGQW
MSMEG_5773|M.smegmatis_MC2_155      GGQDWDPEQSKLSEVARTAMVQNLLTEDNLPSYHREIAMNMGMDGAWGQW
Mflv_1668|M.gilvum_PYR-GCK          GGQDWDPEQSQLSDVARVAMLVNLLTEDNLPSYHREIAMNFSMDGPWGFW
Mvan_5085|M.vanbaalenii_PYR-1       GGQDWDPEQAKLSEVARVAMMVNLLTEDNLPSYHREIAMNFTMDGPWGFW
MAB_0754c|M.abscessus_ATCC_199      GGQDWDPEQSKLSEVAKIAMITNLLTEDNLPSYHREIAMNFTMDGPWGTW
                                    .**** * :::*::**: **: **:******:*******.: ***.** *

Mb0847c|M.bovis_AF2122/97           VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQG
Rv0824c|M.tuberculosis_H37Rv        VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQG
MAV_0772|M.avium_104                VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQV
MLBr_02185|M.leprae_Br4923          VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQG
MMAR_3704|M.marinum_M               VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQQG
MUL_3646|M.ulcerans_Agy99           VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQQG
TH_1577|M.thermoresistible__bu      VNRWTAEENRHGISLRDYLVVTRACDPVELEELRVEQMTRGFSPGQNQQG
MSMEG_5773|M.smegmatis_MC2_155      VNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTRGFSPGQNQQG
Mflv_1668|M.gilvum_PYR-GCK          VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRVEQMTRGFSPGQNDQI
Mvan_5085|M.vanbaalenii_PYR-1       VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRLEQMTRGFSPGQNEQI
MAB_0754c|M.abscessus_ATCC_199      VNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRVEQMTRGFSPGQNRQG
                                    ***********. ::********  ****** **:* :.******** * 

Mb0847c|M.bovis_AF2122/97           --HYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
Rv0824c|M.tuberculosis_H37Rv        --HYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
MAV_0772|M.avium_104                REDLFAESLFDSVIYVTFQELATRISHRNTGKACNETIADQMLAKISADE
MLBr_02185|M.leprae_Br4923          --GLFADTLFDSILYVTFQELATRVSHRNTGKACNETIADQLLAKISSDE
MMAR_3704|M.marinum_M               --DLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
MUL_3646|M.ulcerans_Agy99           --DLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
TH_1577|M.thermoresistible__bu      --DLFAESLFDSVIYVTFQELATRVSHRNTGKACNETVADQLLARISADE
MSMEG_5773|M.smegmatis_MC2_155      --DLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADE
Mflv_1668|M.gilvum_PYR-GCK          EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPIADQLLQRVSADE
Mvan_5085|M.vanbaalenii_PYR-1       EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPVADQLLQRVSADE
MAB_0754c|M.abscessus_ATCC_199      GDELFAESLFDSVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDE
                                        **::: **::**:*******:********. :.:*:::: ::* **

Mb0847c|M.bovis_AF2122/97           NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
Rv0824c|M.tuberculosis_H37Rv        NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
MAV_0772|M.avium_104                NLHMIFYRDVSEAGFAIAPNQAMKSLHKVLRNFQMPGYQVPEFRRKAVMI
MLBr_02185|M.leprae_Br4923          NLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFRRKAVII
MMAR_3704|M.marinum_M               NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
MUL_3646|M.ulcerans_Agy99           NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
TH_1577|M.thermoresistible__bu      NLHMIFYRDVSEAGFEIAPDQAMHSLHRVLRNFKMPGFTVPEFRRKAVVI
MSMEG_5773|M.smegmatis_MC2_155      NLHMIFYRDVSAAGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVI
Mflv_1668|M.gilvum_PYR-GCK          NLHMIFYRDVSEAGFEIAPDQAMRSLHKVLLNFKMPGYTIPDFRRRAVTI
Mvan_5085|M.vanbaalenii_PYR-1       NLHMIFYRDVSEAGFEIAPDQAMKSLHKVLRNFKMPGYTIPDFRRRAVTI
MAB_0754c|M.abscessus_ATCC_199      NLHMIFYRNLVEAGMHIAPDQALKSIHKVLDNFKMPGYTIPGFRRNAVTI
                                    ********::  *.: :.*: *: ::* :* :*:***: :* ***.** *

Mb0847c|M.bovis_AF2122/97           AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
Rv0824c|M.tuberculosis_H37Rv        AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
MAV_0772|M.avium_104                AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAAALRDDLALLIKELE
MLBr_02185|M.leprae_Br4923          AVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELE
MMAR_3704|M.marinum_M               AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
MUL_3646|M.ulcerans_Agy99           AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
TH_1577|M.thermoresistible__bu      AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGKLVEELE
MSMEG_5773|M.smegmatis_MC2_155      AVGGVYDPRIHLDDVVMPVLRKWRIFEREDFTGEGARLRDDLGRLVEELE
Mflv_1668|M.gilvum_PYR-GCK          ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARMRDEIGAHVEELQ
Mvan_5085|M.vanbaalenii_PYR-1       ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARLRDDLGLLVEELQ
MAB_0754c|M.abscessus_ATCC_199      ATGGVYDPQSHLDEVVMPVLRKWRIFERDDISSEGEWYREDLDRIIGDLK
                                    * **:** : **:::*****:****:**:*:..*.   *:::   : :*:

Mb0847c|M.bovis_AF2122/97           LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
Rv0824c|M.tuberculosis_H37Rv        LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
MAV_0772|M.avium_104                TTCDKFEISKRRQLEREARTGKRTTALELHTTAGTLTMSRR
MLBr_02185|M.leprae_Br4923          AACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
MMAR_3704|M.marinum_M               QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
MUL_3646|M.ulcerans_Agy99           QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
TH_1577|M.thermoresistible__bu      EACEKFEVSKQRRLEREARQAEKAAEKKKSFAASTAS----
MSMEG_5773|M.smegmatis_MC2_155      DACDKFEVAKERRLERERKMAEKREMKNLLVSSSSS-----
Mflv_1668|M.gilvum_PYR-GCK          ETVQKFEIAKQRREERLRQMAEKKAAKNLLVGSSAS-----
Mvan_5085|M.vanbaalenii_PYR-1       EAVDKFEVAKQRREERLRQMAEKKAAKNLLVGSSAS-----
MAB_0754c|M.abscessus_ATCC_199      KTSADFEEVKAKYLERQAKRAERQAAKAAREAVSV------
                                     :  .*:  * :  :*  :  ::          .