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MFARNRPILDEHEAAKRNRRNGLIGVLVIAAVLAATGVAFVNTSGMKTYALHLRASGGLRAGDDVRIAGI SVGKVSTVRIDKSLVEATFTVDHAVPVGSESRADIRMLTPLGGHYLALYPEGSTPLGKTPIPPERTSIPF EINELFQKFTPVVKKVDAKVIHDSLMEVANAVDKYPNGLRDFFQSSQSLIKALEPTTEDFHATLNYANEY LRAFKTGKEQLASIVTMMSKLGAKYSKSTTDLIEVFVLLRDLARIFDRFFKAYARDYEPMLNGLDDIVDT LTKYPEKLGKAAEQWGQLVGIVLPMLSGNGITINENDRVIPGQDVCLPHFFRFC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4032 | - | - | 100% (334) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_4151c | - | 5e-19 | 24.83% (302) | MCE-family protein |
| M. abscessus ATCC 19977 | MAB_1008c | - | 9e-18 | 22.11% (294) | putative MCE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3527c | mce4C | 2e-20 | 27.63% (333) | MCE-family protein MCE4C |
| M. gilvum PYR-GCK | Mflv_1558 | - | 1e-20 | 26.32% (304) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv3497c | mce4C | 2e-20 | 27.63% (333) | MCE-family protein MCE4C |
| M. leprae Br4923 | MLBr_02591 | mce1C | 2e-12 | 31.90% (163) | putative secreted protein |
| M. marinum M | MMAR_4985 | mce4C | 6e-19 | 26.65% (319) | MCE-family protein Mce4C |
| M. avium 104 | MAV_5050 | - | 1e-23 | 30.95% (210) | putative Mce family protein |
| M. smegmatis MC2 155 | MSMEG_5898 | - | 3e-22 | 26.14% (306) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_1935 | - | 3e-20 | 27.78% (306) | MCE-FAMILY PROTEIN MCE4C |
| M. ulcerans Agy99 | MUL_3798 | mce5C | 2e-17 | 31.79% (151) | Mce family protein, Mce5C |
| M. vanbaalenii PYR-1 | Mvan_2853 | - | 3e-22 | 26.87% (268) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3527c|M.bovis_AF2122/97 -------MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQ
Rv3497c|M.tuberculosis_H37Rv -------MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQ
MMAR_4985|M.marinum_M -----------MPSSKHDRDPLRTGIFGVVLVICVVLIAFGYSGLPFLPQ
Mflv_1558|M.gilvum_PYR-GCK ------------MARPDDSNPLRTGIFGIALVACLVLVSFGYSSLPFFPQ
MSMEG_5898|M.smegmatis_MC2_155 ------------MASLRDDKTLRTGIFGIVLVTAVVLVSFGYTGLPFFPQ
TH_1935|M.thermoresistible__bu ------------MADTGERNPLRTGIFGIAIVMCVVLVAFGFQTLPFLKQ
Mvan_2853|M.vanbaalenii_PYR-1 ------------MQKYRGSSLVRAGFIGAVLIALVIVVGLQPQQLWSMAT
MLBr_02591|M.leprae_Br4923 ------------MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPILFA
MUL_3798|M.ulcerans_Agy99 MADSSLRHRLSALQRRPLESYNKTWLRFAAVAVVAVVIAAMLVVHLAGAG
MAB_4032|M.abscessus_ATCC_1997 ---MFARNRPILDEHEAAKRNRRNGLIGVLVIAAVLAATG--VAFVNTSG
MAV_5050|M.avium_104 --------------MQPLKILRNPMFWGVNALAIIVVLALTAAAVYVSPP
. : :
Mb3527c|M.bovis_AF2122/97 GKTYDAYFTDAGG-ITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRS
Rv3497c|M.tuberculosis_H37Rv GKTYDAYFTDAGG-ITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRS
MMAR_4985|M.marinum_M GKTYNAYFSDAGG-ITPGNNVYVSGFKVGTVSDVSLAGDAAKITFSVDRH
Mflv_1558|M.gilvum_PYR-GCK GKAYEAYFADAGG-ITPGNDVNVSGINVGKVNSVELAGDAAKITFTVNRE
MSMEG_5898|M.smegmatis_MC2_155 GKPYEAYFADAGG-IEVGNDVNVSGITVGKVSDVELAGDAAKVTFTVDRK
TH_1935|M.thermoresistible__bu GRAYAAYFADAGG-ITPGNAVNISGIKVGDVTGVHLAGDKAKVTFTVDRT
Mvan_2853|M.vanbaalenii_PYR-1 SVRYQAVFAESGG-LAAGNNVKVSGVTVGSVSDVELDRGTAVVTFSVAGA
MLBr_02591|M.leprae_Br4923 RPSYYGQFTDTGG-LNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIG-T
MUL_3798|M.ulcerans_Agy99 YRRYTAEFLQAAA-LRAGNPIAIAGIPVGTVTSMKLVGDHVEAGLRIRDD
MAB_4032|M.abscessus_ATCC_1997 MKTYALHLRASGG-LRAGDDVRIAGISVGKVSTVRIDKSLVEATFTVDHA
MAV_5050|M.avium_104 GEKSVVFFTDDAASVRPGEDVRIAGITVGRVKDLSIEPNQVKVRASVDSS
: .. : *: : ::*. ** * : : . . :
Mb3527c|M.bovis_AF2122/97 IVVGDQSLAAIRTDTILGERSIAVSPAGS---GKSTTIPLSRTTTPYTLN
Rv3497c|M.tuberculosis_H37Rv IVVGDQSLAAIRTDTILGERSIAVSPAGS---GKSTTIPLSRTTTPYTLN
MMAR_4985|M.marinum_M VVVGDQSLAAIRTDTILGERSVAVTPAGS---GNATTIPLSRTTTPYTLN
Mflv_1558|M.gilvum_PYR-GCK VKVGDQSLVAIKTDTVLGEKSLSVTPKGN---GESTVIPLGRTTTPYTLN
MSMEG_5898|M.smegmatis_MC2_155 IKVGDQSLVAIKTDTVLGQKSLSVTPKGA---GSPSVIPLGRTTTPYTLN
TH_1935|M.thermoresistible__bu VRVGDQSLASIKTDTVLGEKSLALKPAGS---GQVTVIPAERTTSPYTLN
Mvan_2853|M.vanbaalenii_PYR-1 VPLGGDTTASIGIATVLGERVLVLRPAGRESLGAMGVIPLSRTGSPYSLT
MLBr_02591|M.leprae_Br4923 NRIGTASRLGIRTDTVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQSY
MUL_3798|M.ulcerans_Agy99 VVLGKDSTATIRVTTILGSRYLAIEPDGAAS-LPDHTFDLAHTAVPYDLQ
MAB_4032|M.abscessus_ATCC_1997 VPVGSESRADIRMLTPLGGHYLALYPEGSTP-LGKTPIPPERTSIPFEIN
MAV_5050|M.avium_104 AFVGDQSQIQVRMLTVVGGYYVNLVSLGNKP-LGNRAIPLERVTMPYNLM
:* : : * :* : : . * : : *:
Mb3527c|M.bovis_AF2122/97 GVLQDLGRNANDLNRPQFEQALNVFTQALH-DATPQVRGAVDGLTSLSRA
Rv3497c|M.tuberculosis_H37Rv GVLQDLGRNANDLNRPQFEQALNVFTQALH-DATPQVRGAVDGLTSLSRA
MMAR_4985|M.marinum_M GALQDLGGSASNLDKPQFEHALQVLTETLH-DATPQLRGALDGVTALSRT
Mflv_1558|M.gilvum_PYR-GCK TALQDLGQNVGELDKPQFEMALQTLTDSLK-DATPHLRSALDGVTNLSRS
MSMEG_5898|M.smegmatis_MC2_155 TALQDLGQNVGELDKPRFEQALQTLTDTLR-DATPQLRSALDGVANLSRS
TH_1935|M.thermoresistible__bu NALQDLTTNVGDLDQERFTEALGLLTEALQ-DATPHLRSTLDGVTALSAS
Mvan_2853|M.vanbaalenii_PYR-1 DAIGEFTSNTEQTDTAAINQSLDTLSDTIE-RIAPQLAPTFDGVTRLSKS
MLBr_02591|M.leprae_Br4923 DAFFDATKVASGWNIDTIKQSLKVVSETID-QTYPHLSAALDGVAKFSDT
MUL_3798|M.ulcerans_Agy99 AALKDATTTFEQVDSDRFAQSLTVLGRQLD-KLPPVVPQAVANIDSLSSI
MAB_4032|M.abscessus_ATCC_1997 ELFQKFTPVVKKVDAKVIHDSLMEVANAVD-KYPNGLRDFFQSSQSLIKA
MAV_5050|M.avium_104 RALTDATKITEGVDPKPIRQSLDRIQAGLNGTNVDTLSAVIDAGNALTST
: . : : :* . : : . :
Mb3527c|M.bovis_AF2122/97 LNRRDEALQGLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAAL
Rv3497c|M.tuberculosis_H37Rv LNRRDEALQGLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAAL
MMAR_4985|M.marinum_M LNTRDEALQGLLAHAKTVTGVLSERAAQVNKLIQDGNQLFAALDERRSAL
Mflv_1558|M.gilvum_PYR-GCK LNKRDEALDQLLARAKNVSDTLAQRSGQVNQLITDGNLLFAALDERRQAL
MSMEG_5898|M.smegmatis_MC2_155 INRRDEALGQLLEHAKRVSDLLAQRAGQVNQLITDGNQLFAALDARRQAL
TH_1935|M.thermoresistible__bu INANDAAIAQLLARARSVSQVLAERAGQVNQLVLDGNRLLAALDERRAAL
Mvan_2853|M.vanbaalenii_PYR-1 LNSRNESLSGLLEAASDVTGVLSERSAQVNSLLLNANDLLAVLQQRRYAI
MLBr_02591|M.leprae_Br4923 IGARDKEIKHLIAQANQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAV
MUL_3798|M.ulcerans_Agy99 IATRRDQLGQLLESTEQVTNTLRRQLSTIGGLVNQGQDLMGQFVARRAVF
MAB_4032|M.abscessus_ATCC_1997 LEPTTEDFHATLNYANEYLRAFKTGKEQLASIVTMMSKLGAKYSKSTTDL
MAV_5050|M.avium_104 IDRQRGQITTILNLSDEYIDQLSNYRERLQELVSKLSILEQTLVLYGKGF
: : : : : : :: . * .
Mb3527c|M.bovis_AF2122/97 SALISGIDDVAAQISG----FVADNRKEFGPALSKLNLVLANLNERRDYI
Rv3497c|M.tuberculosis_H37Rv SALISGIDDVAAQISG----FVADNRKEFGPALSKLNLVLANLNERRDYI
MMAR_4985|M.marinum_M GALISGIDDVSVQLSG----FVNDNRKEFGPALSKLNLVVSNLNERRDYI
Mflv_1558|M.gilvum_PYR-GCK SNLIAGIDDVATQISG----FVADNRREFKPALEKLNLVLDNLLERREHI
MSMEG_5898|M.smegmatis_MC2_155 STLIDGIDDVSRQLSG----FVADNRREFKPALDKLNLVMDNLLERREHI
TH_1935|M.thermoresistible__bu SALIAGIDDVSEQLSG----FVADNRREFGPALAKLNLVLDNLLERREHI
Mvan_2853|M.vanbaalenii_PYR-1 VNLLASTTAVAQQLSG----MVADNERELAPTLEKLNTVAEMLERNRDNI
MLBr_02591|M.leprae_Br4923 DALLGNVAAFAAQVQR----LINDNP-NLNHVLEQLHQLSGILVQHKDDL
MUL_3798|M.ulcerans_Agy99 HAMMRSLDGFVGTLRQ----IIGDRP-GVDALLKDMREFTGLLAQHDDLL
MAB_4032|M.abscessus_ATCC_1997 IEVFVLLRDLARIFDR----FFKAYARDYEPMLNGLDDIVDTLTKYPEKL
MAV_5050|M.avium_104 AGALSGMGDIGDAFLEPFGKFWVNHREEFIEKVREWQDRFRRWANDNSRI
: . . : : . . :
Mb3527c|M.bovis_AF2122/97 TEALKRL-PTYATTLGEVVGSGPGFNVNVYSVLPGPLVATVFDLVF----
Rv3497c|M.tuberculosis_H37Rv TEALKRL-PTYATTLGEVVGSGPGFNVNVYSVLPGPLVATVFDLVF----
MMAR_4985|M.marinum_M TEALKRL-PAYATTLGEVVGSGPGFNVNVNSVLPAPMVAMVFDTVF----
Mflv_1558|M.gilvum_PYR-GCK GEALKRL-PAYATALGEVVGSGPGFQINLYGLPPAPIAEVLLDTYF----
MSMEG_5898|M.smegmatis_MC2_155 GEALRRL-PPYATALGEVVGSGPGFQINLYGLPPAAISEVLLDTYF----
TH_1935|M.thermoresistible__bu SAALKRG-PAYATALGEVVGSGPGFHINLYGLPPGPMAEVLLDVYF----
Mvan_2853|M.vanbaalenii_PYR-1 TASLKGL-AKYQVTQGEAVNNGFFYNGFASNLLPGPAIQPFLDYALGYR-
MLBr_02591|M.leprae_Br4923 ANTLIQV-AAFLPSLNEAIGSGPFFKVVLHNLAPYQILQPWVDAAFKKRG
MUL_3798|M.ulcerans_Agy99 SNLLQIS-PIFFREATNITGDGNAVNFNAPNG--LLLVDSWMRAIS----
MAB_4032|M.abscessus_ATCC_1997 GKAAEQWGQLVGIVLPMLSGNGITINENDRVIPGQDVCLPHFFRFC----
MAV_5050|M.avium_104 IPRLRRIRDKIERVLDAQNARPELLATDLCIPMPGSPC------------
Mb3527c|M.bovis_AF2122/97 -------QPGKLPDSLADYLRGFIQERWIIRPKSP---------------
Rv3497c|M.tuberculosis_H37Rv -------QPGKLPDSLADYLRGFIQERWIIRPKSP---------------
MMAR_4985|M.marinum_M -------QPGKLPDSFADYLRGLIQERWIIRPKSP---------------
Mflv_1558|M.gilvum_PYR-GCK -------QPGKLPDSLSDMLRGYISERMILRPKSP---------------
MSMEG_5898|M.smegmatis_MC2_155 -------QPGKLPDSLADMLRGYIAERTIVRPKSP---------------
TH_1935|M.thermoresistible__bu -------QPGKLPDSLADYLRGFISERLILRPKSP---------------
Mvan_2853|M.vanbaalenii_PYR-1 ----RGVDAGQPPDNAGPRAEFPFPYNGIPGGSR----------------
MLBr_02591|M.leprae_Br4923 IDPENFWRSAGLPEFRFPDPNGTRFPNGAPPPAPPVLEGTPENPGPAVPP
MUL_3798|M.ulcerans_Agy99 --------GRAEQFGMIPYFKDCK--------------------------
MAB_4032|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5050|M.avium_104 --------------------------------------------------
Mb3527c|M.bovis_AF2122/97 --------------------------------------------------
Rv3497c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4985|M.marinum_M --------------------------------------------------
Mflv_1558|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5898|M.smegmatis_MC2_155 --------------------------------------------------
TH_1935|M.thermoresistible__bu --------------------------------------------------
Mvan_2853|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 GSPCSYTPAHPGGNNTIGDEMGLPRPWNPLPCAGATAGPYGGPAFPAPID
MUL_3798|M.ulcerans_Agy99 --------------------------------------------------
MAB_4032|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5050|M.avium_104 --------------------------------------------------
Mb3527c|M.bovis_AF2122/97 --------------------------------------------------
Rv3497c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4985|M.marinum_M --------------------------------------------------
Mflv_1558|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5898|M.smegmatis_MC2_155 --------------------------------------------------
TH_1935|M.thermoresistible__bu --------------------------------------------------
Mvan_2853|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 VQTSPPNPDGLPLLPGIAIAGRPGDPAPNVPGTPVPLPPNAPPGARTEQL
MUL_3798|M.ulcerans_Agy99 --------------------------------------------------
MAB_4032|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5050|M.avium_104 --------------------------------------------------
Mb3527c|M.bovis_AF2122/97 ----------------------------------------
Rv3497c|M.tuberculosis_H37Rv ----------------------------------------
MMAR_4985|M.marinum_M ----------------------------------------
Mflv_1558|M.gilvum_PYR-GCK ----------------------------------------
MSMEG_5898|M.smegmatis_MC2_155 ----------------------------------------
TH_1935|M.thermoresistible__bu ----------------------------------------
Mvan_2853|M.vanbaalenii_PYR-1 ----------------------------------------
MLBr_02591|M.leprae_Br4923 APAAPAQDSSAPHEPREQLSAPLINPGGTGGSGGAGGSRN
MUL_3798|M.ulcerans_Agy99 ----------------------------------------
MAB_4032|M.abscessus_ATCC_1997 ----------------------------------------
MAV_5050|M.avium_104 ----------------------------------------