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AVIRGSALTNYHELVAELGGDGSRLLAGARVSPTDAGSYERFISLPNGARALEATAAALNAPDFGRQLAR RQGIEILGPVGLAARTAATVADAFAILEKFMGAYCPVISARVTDHRDPALCRFEFEYLLNPAPPQAQAVE LSLGVTLRVLHHFLGAGYRPVSVHLPHQALTPASAYQRYFGCPPFFCEPVGGFTLRATDMQKALPKDNLA HQTAVDYLTGTHASRKPDSSQLVRILIRQLLPTGAIGLGDIALHLGVHPKTLQRRLRAEGMTFAELVDQI RREAAERLLSDTDLSLDHLSRQLGYAEQSVFTRSCKRWFGTTPSAYRSDRRRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3997c | - | - | 100% (334) | transcriptional regulatory protein |
| M. abscessus ATCC 19977 | MAB_3623 | - | 7e-28 | 27.03% (333) | AraC family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2050 | - | 4e-15 | 27.74% (274) | putative HTH-type transcriptional regulator AraC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3763 | - | 8e-92 | 52.54% (335) | transcriptional regulatory protein AraC/XylS-family |
| M. gilvum PYR-GCK | Mflv_4594 | - | 8e-12 | 36.22% (127) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv3736 | - | 8e-92 | 52.54% (335) | transcriptional regulatory protein AraC/XylS-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_5276 | - | 1e-87 | 51.20% (332) | AraC/XylS family transcriptional regulator |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6839 | - | 1e-07 | 35.29% (85) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3718 | - | 1e-08 | 31.86% (113) | PUTATIVE putative aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_4350 | - | 9e-88 | 51.20% (332) | AraC/XylS family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5829 | - | 3e-06 | 36.71% (79) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3763|M.bovis_AF2122/97 MSVVRGTALANYP----------SLVAGLGGDPATLLRAAG---------
Rv3736|M.tuberculosis_H37Rv MSVVRGTALANYP----------SLVAGLGGDPATLLRAAG---------
MMAR_5276|M.marinum_M MSVVRGTGLSNYP----------NLVSELGGDPAALLRAAG---------
MUL_4350|M.ulcerans_Agy99 MSVVRGTGLSNYP----------NLVSELGGDPAALLRAAG---------
MAB_3997c|M.abscessus_ATCC_199 MAVIRGSALTNYH----------ELVAELGGDGSRLLAGAR---------
Mflv_4594|M.gilvum_PYR-GCK MDWAQGARSVKFSNAGVPPVAFVQMLESQALDPDAVARLRT---------
TH_3718|M.thermoresistible__bu VAAADLIDTA----------------VEAGIPADRCLRGTW---------
MSMEG_6839|M.smegmatis_MC2_155 ---MRRVAVLAVP----------DVVAFDLSIPIEVFGRVR---------
Mvan_5829|M.vanbaalenii_PYR-1 MAENSRTVVFALYN---------KVTLQDVAAPLEIFARANDFGARYTVL
Mb3763|M.bovis_AF2122/97 VRDQDVGNYDAFISIRAAI--------RAIESAAAVTATMDFGRRLAQRQ
Rv3736|M.tuberculosis_H37Rv VRDQDVGNYDAFISIRAAI--------RAIESAAAVTATMDFGRRLAQRQ
MMAR_5276|M.marinum_M VREQDVGNYDAFIPVRAVI--------RAIETAAAATGTHDFGRQLAQRQ
MUL_4350|M.ulcerans_Agy99 VREQDVGNYDAFIPVRAVI--------RAIETAAAATGTHDFGRQLAQRQ
MAB_3997c|M.abscessus_ATCC_199 VSPTDAGSYERFISLPNGA--------RALEATAAALNAPDFGRQLARRQ
Mflv_4594|M.gilvum_PYR-GCK IMAREGTDEATLMQHDVQAPL---RWFRDLYPDLDVDRATLLGFSFAGQA
TH_3718|M.thermoresistible__bu LTRSDLAAADRLITAEQELR-------IVRNVLAATEHPTALAGSAGARY
MSMEG_6839|M.smegmatis_MC2_155 LADGMNGYRVQVCGTEPTVSA---GPLRIATDHGLEALADADTIIVPGRE
Mvan_5829|M.vanbaalenii_PYR-1 LASPTGGAVGTTAYAQLNADLPLSEVPESIDTLLVPGGVPADFNFTPGIH
:
Mb3763|M.bovis_AF2122/97 GIEILGPVG----VAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAG-
Rv3736|M.tuberculosis_H37Rv GIEILGPVG----VAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAG-
MMAR_5276|M.marinum_M GIEILGPVG----VAARTAATVADALMIFHTFMAAYSPAIHIEITPLAHT
MUL_4350|M.ulcerans_Agy99 GIEILGPVG----VAARTAATVADALMIFHTFMAAYSPAIHIEITPLART
MAB_3997c|M.abscessus_ATCC_199 GIEILGPVG----LAARTAATVADAFAILEKFMGAYCPVISARVTDHRDP
Mflv_4594|M.gilvum_PYR-GCK QLTSFGPLS----VPLVSAGSVAEIVELLT-----YLPLITTAINAQFRP
TH_3718|M.thermoresistible__bu QLPRAGFLG----FALLSSNTLGDAIRVGIR----FWRLTSVFERVTLEV
MSMEG_6839|M.smegmatis_MC2_155 NLPTQTPAP----VVTALRDAYASGATIASICTGAFVLADTGLLDGRRAT
Mvan_5829|M.vanbaalenii_PYR-1 DIPEEPTPDSVPDAMAMVRELAPRARRVASVCTGAFVLAALGLLDNRRAT
: : :
Mb3763|M.bovis_AF2122/97 QRSFIALEFLLDEPASYPQTMELALG-VALGVIRLLLGADYAPLAVHLPH
Rv3736|M.tuberculosis_H37Rv QRSFIALEFLLDEPASYPQTMELALG-VALGVIRLLLGADYAPLAVHLPH
MMAR_5276|M.marinum_M QRSFVAIEIVPDDPIPCPHTLELALG-VSLGVFRLLMGADYTPLAVHLPH
MUL_4350|M.ulcerans_Agy99 QRSVVAIEIVPDDPIPCPHTLELALG-VSLGVFRLLMGADYTPLAVHLPH
MAB_3997c|M.abscessus_ATCC_199 ALCRFEFEYLLNPAPPQAQAVELSLG-VTLRVLHHFLGAGYRPVSVHLPH
Mflv_4594|M.gilvum_PYR-GCK NDQGLTVGLWGHTGDRALDCLAVTYTGSALLRLLDMLVSDALTVTLHLSW
TH_3718|M.thermoresistible__bu NRQTTAIVLDDRDVPADVRQFLVERDAATMVGVTPALLGGPLPDGVRMSL
MSMEG_6839|M.smegmatis_MC2_155 THWAAADLFRANFPAVDLDPDVLYVD--AGRILTSAGASAGVDLCLHMVQ
Mvan_5829|M.vanbaalenii_PYR-1 THWAHCQTLARTYPKVMVDPDSLFVQ--DGPFITGAGITAGIDLALALVE
: . : :
Mb3763|M.bovis_AF2122/97 DPLT--PEAFYLQYFGCRPYFAERVGGFTMRTADLSRPLNR-DDVAHRVV
Rv3736|M.tuberculosis_H37Rv DPLT--PEAFYLQYFGCRPYFAERVGGFTMRTADLSRPLNR-DDVAHRVV
MMAR_5276|M.marinum_M DPLT--PPTTYVRYFECTPHFAERRSGFTVRSTDLVRPLHR-DELAHRAV
MUL_4350|M.ulcerans_Agy99 DPLT--PPTTYVRYFECTPHFAERRSGFTVRSTDLVRPLHR-DELAHRAV
MAB_3997c|M.abscessus_ATCC_199 QALT--PASAYQRYFGCPPFFCEPVGGFTLRATDMQKALPK-DNLAHQTA
Mflv_4594|M.gilvum_PYR-GCK SAPVSLNKLAAEMVLAGRLFFDAPMSYLHVPVNALNEVCRFSDPLAYRLA
TH_3718|M.thermoresistible__bu RRRPN-GDAAVEELVDVS--YGADRNAITFPTALLDRPLAAANPAVAAQC
MSMEG_6839|M.smegmatis_MC2_155 RDHG----------------AAAAANAAKMAVAPLHRSGGQ-----AQFI
Mvan_5829|M.vanbaalenii_PYR-1 SDYG----------------PAVARRVARWMVVFLQRPGGQ---------
: .
Mb3763|M.bovis_AF2122/97 VDYLS-SITPLGEGIVESVRTIVRQLLPTGAA-TLNVVAEQFHLHPKTLQ
Rv3736|M.tuberculosis_H37Rv VDYLS-SITPLGEGIVESVRTIVRQLLPTGAA-TLNVVAEQFHLHPKTLQ
MMAR_5276|M.marinum_M VDYLS-SITPLGAGIVESVRTMARQLLPTGAA-TLEVVAAQFHLHPKTLQ
MUL_4350|M.ulcerans_Agy99 VDYLS-SITPLGAGIVESVRTMARQLLPTGAT-TLEVVAAQFHLHPKTLQ
MAB_3997c|M.abscessus_ATCC_199 VDYLTGTHASRKPDSSQLVRILIRQLLPTGAI-GLGDIALHLGVHPKTLQ
Mflv_4594|M.gilvum_PYR-GCK VAELRRTLDEQSGATSFSKKVRRLLDEDPGQR-SCQRVADELSVSTSTLK
TH_3718|M.thermoresistible__bu IAQCDELLARHQDEPTVASRVRRRLARDPGAVPLMRTLATEMGFTERTLR
MSMEG_6839|M.smegmatis_MC2_155 IRNQP--PASVIGEKTHLSEVLVWIEQNAHRELTLSDIADHAATSIRTLN
Mvan_5829|M.vanbaalenii_PYR-1 -AQFSVWAEATLPATGGLRAVVDSVVADPGADHSIAAMAARAAVSERHLV
. :* . *
Mb3763|M.bovis_AF2122/97 RRLAEEN-TTFVILVDRVRKDVADRYLRTTGIGLTHLARELGYAEQSVLT
Rv3736|M.tuberculosis_H37Rv RRLAEEN-TTFVILVDRVRKDVADRYLRTTGIGLTHLARELGYAEQSVLT
MMAR_5276|M.marinum_M RRLADES-TTFAALIDEVRKETADRYLRTTAMSLSHLARELGYAEQSVLT
MUL_4350|M.ulcerans_Agy99 RRLADES-TTFAALIDEVRKETADRYLRTTAMSLSHLARELGYAEQSVLT
MAB_3997c|M.abscessus_ATCC_199 RRLRAEG-MTFAELVDQIRREAAERLLSDTDLSLDHLSRQLGYAEQSVFT
Mflv_4594|M.gilvum_PYR-GCK RRLAEEG-TTFRELRQSCLRESAMMLLITRSMSASQIATELGYGDLANFS
TH_3718|M.thermoresistible__bu RRLAREG-TGYRSLIDEVRGARAADLLSG-GATVKQVAQQLGYSEPAAFH
MSMEG_6839|M.smegmatis_MC2_155 RRFQAETGQTPMQWVTGVRIRHAQELLERTSLSVERIGRDVGFTSAANFR
Mvan_5829|M.vanbaalenii_PYR-1 RMFREQVGMTPARFVEQARLEAAKVLLATGDKGQDAVARRAGFGTPDTMR
* : : * * :. *: :
Mb3763|M.bovis_AF2122/97 RSCKRWFGTGPAAYRNQARLQTTVSAPGSGRGPNPGNVSVSC
Rv3736|M.tuberculosis_H37Rv RSCKRWFGTGPAAYRNQARLQTTVSAPGSGRGPNPGNVSVSC
MMAR_5276|M.marinum_M RSCKRWFGIGPAAYRAKTRVRATPRRR---------------
MUL_4350|M.ulcerans_Agy99 RSCKRWFGIGPAAYRAKTRVRATPRRR---------------
MAB_3997c|M.abscessus_ATCC_199 RSCKRWFGTTPSAYRSDRRRA---------------------
Mflv_4594|M.gilvum_PYR-GCK HAFKRWTGRSPSEYRRSQR-----------------------
TH_3718|M.thermoresistible__bu HAFVRWHALPPARFRRADVR----------------------
MSMEG_6839|M.smegmatis_MC2_155 EQFRRLSGVAPQVYRNTFRERTQDIPHTTSTALASA------
Mvan_5829|M.vanbaalenii_PYR-1 RTFRRNLGISPSTYRSRFRTTGIDR-----------------
. * . * :*