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AENSRTVVFALYNKVTLQDVAAPLEIFARANDFGARYTVLLASPTGGAVGTTAYAQLNADLPLSEVPESI DTLLVPGGVPADFNFTPGIHDIPEEPTPDSVPDAMAMVRELAPRARRVASVCTGAFVLAALGLLDNRRAT THWAHCQTLARTYPKVMVDPDSLFVQDGPFITGAGITAGIDLALALVESDYGPAVARRVARWMVVFLQRP GGQAQFSVWAEATLPATGGLRAVVDSVVADPGADHSIAAMAARAAVSERHLVRMFREQVGMTPARFVEQA RLEAAKVLLATGDKGQDAVARRAGFGTPDTMRRTFRRNLGISPSTYRSRFRTTGIDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5829 | - | - | 100% (338) | AraC family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0972 | - | 5e-60 | 42.34% (333) | AraC family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5828 | - | 1e-51 | 39.60% (303) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 9e-22 | 31.21% (282) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1008 | - | 1e-163 | 84.34% (332) | Fis family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1931c | - | 9e-22 | 31.21% (282) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4754 | - | 2e-77 | 46.06% (330) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 2e-61 | 43.03% (330) | transcriptional regulatory protein |
| M. avium 104 | MAV_4981 | - | 5e-78 | 46.43% (336) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_0376 | - | 1e-157 | 81.36% (338) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 3e-42 | 40.25% (241) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_2902 | - | 8e-61 | 43.03% (330) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5829|M.vanbaalenii_PYR-1 -------MAENS----RTVVFALYNKVTLQDVAAPLEIFARANDFGARYT
Mflv_1008|M.gilvum_PYR-GCK ---MTDEFRHNADPGGKTVVFALYDKVTLQDVAAPMEIFARANDFGASYR
MSMEG_0376|M.smegmatis_MC2_155 MPWNEDEGMPPVLSDPRTVVFALYDKVTLADVAAPLEIFARANDFGANYT
MAB_4754|M.abscessus_ATCC_1997 --------MSDE----RLITIVVFDGMKLLDLAGPAEVFAEANRFGANYR
MAV_4981|M.avium_104 --------MADSSATPRVVVIVVFDDVTMLDVAGAGEVFAEANRFGADYL
TH_3120|M.thermoresistible__bu ------------------VAALVLDGLAIFEFGVICEVFG-VDRTDDGVP
Mb1966c|M.bovis_AF2122/97 ------------------MVIVGFPG------------------------
Rv1931c|M.tuberculosis_H37Rv ------------------MVIVGFPG------------------------
MMAR_2855|M.marinum_M --------------MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEGGY
MUL_2902|M.ulcerans_Agy99 --------------MARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEGGY
:.
Mvan_5829|M.vanbaalenii_PYR-1 VLLASPTGGAVGTTAYAQLNADLPLSEVPESIDTLLVPGGVPADFNFTPG
Mflv_1008|M.gilvum_PYR-GCK VLTVSPSGRPVGTTAFATLNVDVALDAAPDAFDTLLVPGGVPADFSFTPG
MSMEG_0376|M.smegmatis_MC2_155 VLLASLTGTAVGTTAFAKLDANVALDEVPAAVDTLVVPGGVPAGFSFTPG
MAB_4754|M.abscessus_ATCC_1997 LVVASVDGRDVSTSIGSPFSVTETIDSI-ECADTVLVAG--------GDV
MAV_4981|M.avium_104 LKIASVDGRDVTTSIGTRLGVTDAVSSI-ESADTVLVAG--------SDN
TH_3120|M.thermoresistible__bu PVDFTVCGPRAGQPVRTSFGATLTPDSGLDGLAG--------------AD
Mb1966c|M.bovis_AF2122/97 -----------------------------DPVDTVILPG--------GAG
Rv1931c|M.tuberculosis_H37Rv -----------------------------DPVDTVILPG--------GAG
MMAR_2855|M.marinum_M DVALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPG--------GGG
MUL_2902|M.ulcerans_Agy99 DVALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPG--------GGG
Mvan_5829|M.vanbaalenii_PYR-1 IHDIPEEPTPDSVPDAMAMVRELAPRARRVASVCTGAFVLAALGLLDNRR
Mflv_1008|M.gilvum_PYR-GCK LHDIPEEPTPDSVADACDMVRRLAPRARRIASVCTGSFVLAALGLLDGRR
MSMEG_0376|M.smegmatis_MC2_155 LHDIPEEPTPDTIPDAVHLVRHLAPRARRVASVCTGAFVLAALGLLNGRR
MAB_4754|M.abscessus_ATCC_1997 LIGSPLNP------TLVAALAQLQARCRRIASICTGAFLLAQAGMLDHRR
MAV_4981|M.avium_104 LPRRPIDP------ELVEAVKSVADRTRRLASICTGSFILGQAGLLDGRR
TH_3120|M.thermoresistible__bu LVAIPAIRQDDYLPEALDAVRAAADAGAIILTVCSGAFLAGAAGLLDGRP
Mb1966c|M.bovis_AF2122/97 VDAARSEP------ALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLG--R
Rv1931c|M.tuberculosis_H37Rv VDAARSEP------ALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLG--R
MMAR_2855|M.marinum_M VDAARDNV------ALMDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCR
MUL_2902|M.ulcerans_Agy99 VDAARDNV------ALMDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCR
: : : ::*:*:*: . *:*.
Mvan_5829|M.vanbaalenii_PYR-1 ATTHWAHCQTLARTYPKVMVDPDSLFVQ-DGPFITGAGITAGIDLALALV
Mflv_1008|M.gilvum_PYR-GCK ATTHWAHCQTLARQYPAVMVDPDSLFVQ-DGPFITGAGITAGIDLALAMV
MSMEG_0376|M.smegmatis_MC2_155 ATTHWAHCQTLARNYPHVRVDPDSLFVQ-DGRFFTGAGISAGTDLALALV
MAB_4754|M.abscessus_ATCC_1997 ATTHWRHTGLLQRAFPNVTVEPDAIFVR-DANVFTSAGVSAGIDLALALV
MAV_4981|M.avium_104 ATTHWHDVRLFARAFPEITVEPDALFVC-DGDVFTSAGISSGIDLALALV
TH_3120|M.thermoresistible__bu CTTHWGLTEELARRYPTARVDRNVLYVD-DGDLITSAGTAAGIDACLHLV
Mb1966c|M.bovis_AF2122/97 TPSDDALG--LCRTFRPR-ISGRSGRCRPDLHAQFAEGVDRGWSHRRHRP
Rv1931c|M.tuberculosis_H37Rv TPSDDALG--LCRTFRPR-ISGRSGRCRPDLHAQFAEGVDRGWSHRRHRP
MMAR_2855|M.marinum_M ATTHWAFADRLAREFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALV
MUL_2902|M.ulcerans_Agy99 ATTHWAFADRLAREFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALV
.:. : * : :. . . * * .
Mvan_5829|M.vanbaalenii_PYR-1 ESDYGPAVARRVARWMVVFLQRPGGQAQFSVWAEATLPATGGLRAVVDSV
Mflv_1008|M.gilvum_PYR-GCK ESDFGPAVARRVARWMVVFLQRPGGQAQFSVWAESALPVTGGLRAVVDSV
MSMEG_0376|M.smegmatis_MC2_155 ESDHGPTMARRVARWMVVFLQRPGGQAQFSVWSG--LPAADGLREIMDSV
MAB_4754|M.abscessus_ATCC_1997 EDDHGSEMVRDVARSLVVYLKRAGGQSQFSVFVESALPTGSALRPATDAI
MAV_4981|M.avium_104 EMDYGTELVRAVARWLVVYLKRAGGQSQFSALVEAEPPPRSPLRKVTAAI
TH_3120|M.thermoresistible__bu RRELGSEVTNTIARHMVVPPQRDGGQRQFIDQPIPVRHSEG-FAPHLDWI
Mb1966c|M.bovis_AF2122/97 RAGTGRRRPRHRDCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPP
Rv1931c|M.tuberculosis_H37Rv RAGTGRRRPRHRDCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPP
MMAR_2855|M.marinum_M EGDHGTEIAQTVARWLVLYLRRPGGQ-TQFAAPVWMP--RAKRPSIRDVQ
MUL_2902|M.ulcerans_Agy99 EGDHGTEIAQTVARWLVLYLRRPCGQ-TQFAAPVWMP--RAKRPSIRDVQ
. * . * .
Mvan_5829|M.vanbaalenii_PYR-1 VAD-----PGADHSIAAMAARAAVSERHLVRMFREQVGMTPARFVEQARL
Mflv_1008|M.gilvum_PYR-GCK IAD-----PAGDHSLAAMASRAAVSERHLVRVFRDQVGMTPARFVEQARL
MSMEG_0376|M.smegmatis_MC2_155 IAH-----PGAEHSLAALAARAAVSERHLVRMFREQVGMTPARFVEQARL
MAB_4754|M.abscessus_ATCC_1997 AAD-----PAADHSVAKLAARAALSARQLTRLFHSELGTTPARYVELVRI
MAV_4981|M.avium_104 SAD-----PAADHSVKSLSARASLSTRQLTRLFQSELGTTPARYVEMVRI
TH_3120|M.thermoresistible__bu LSN-----LDKTHTVASLARRANMSPRTFARRFVEETGRTPMQWVTDQRV
Mb1966c|M.bovis_AF2122/97 GAGGHRGRAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRT
Rv1931c|M.tuberculosis_H37Rv GAGGHRGRAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRT
MMAR_2855|M.marinum_M EA--IEAQPGGPHSIEELAHRAAMSPRHFTRVFTGEVGEAPRQYVERVRT
MUL_2902|M.ulcerans_Agy99 EA--IEAQPGGPHSIEELAHRAAMSPRHFTRVFTGEVGEAPGRYVERVRT
: * : :: ** :* * :.* * : * :* ::* *
Mvan_5829|M.vanbaalenii_PYR-1 EAAKVLLATGDKGQDAVARRAGFGTPDTMRRTFRRNLGISPSTYRSRFRT
Mflv_1008|M.gilvum_PYR-GCK EAAKVLLATGDHSQDSVARRSGFGTPDTMRRTFRRNLGISPGVYRNRFRT
MSMEG_0376|M.smegmatis_MC2_155 EAAKVLLATGDQSQDAVARLVGFGSPDTMRRTFRRNLGISPGLYRNRFRT
MAB_4754|M.abscessus_ATCC_1997 DAARGALDAG-STVTEAARIAGFGSAETLRRAFVSELGVSPKAYRERFRT
MAV_4981|M.avium_104 DAARAALDAG-RSVAESARLAGFGSAETLRRVFVEHLGLSPKAYRDRFRT
TH_3120|M.thermoresistible__bu LYARRLLEETDLDIHRIAARCGFGSTTLLRHHFRRVIGVTPSDYRRRFAC
Mb1966c|M.bovis_AF2122/97 EAARRQLEETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA-
Rv1931c|M.tuberculosis_H37Rv EAARRQLEETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA-
MMAR_2855|M.marinum_M EAARRQLEETEDTVVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA-
MUL_2902|M.ulcerans_Agy99 EAARRQLEETEDTVVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA-
*: * * ***:. :*: * :*::* ** *
Mvan_5829|M.vanbaalenii_PYR-1 TGIDR-----------
Mflv_1008|M.gilvum_PYR-GCK TGVDA-----------
MSMEG_0376|M.smegmatis_MC2_155 TGIDRQ----------
MAB_4754|M.abscessus_ATCC_1997 AAR-------------
MAV_4981|M.avium_104 AARG------------
TH_3120|M.thermoresistible__bu GSTTSGSTESGAEVTD
Mb1966c|M.bovis_AF2122/97 ----------------
Rv1931c|M.tuberculosis_H37Rv ----------------
MMAR_2855|M.marinum_M ----------------
MUL_2902|M.ulcerans_Agy99 ----------------