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MSVVRGTALANYPSLVAGLGGDPATLLRAAGVRDQDVGNYDAFISIRAAIRAIESAAAVTATMDFGRRLA QRQGIEILGPVGVAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAGQRSFIALEFLLDEPASYPQTME LALGVALGVIRLLLGADYAPLAVHLPHDPLTPEAFYLQYFGCRPYFAERVGGFTMRTADLSRPLNRDDVA HRVVVDYLSSITPLGEGIVESVRTIVRQLLPTGAATLNVVAEQFHLHPKTLQRRLAEENTTFVILVDRVR KDVADRYLRTTGIGLTHLARELGYAEQSVLTRSCKRWFGTGPAAYRNQARLQTTVSAPGSGRGPNPGNVS VSC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3736 | - | - | 100% (353) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARAC/XYLS-FAMILY) |
| M. tuberculosis H37Rv | Rv3082c | virS | 3e-48 | 36.78% (329) | virulence-regulating transcriptional regulator VirS |
| M. tuberculosis H37Rv | Rv1395 | - | 4e-13 | 41.25% (80) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3763 | - | 0.0 | 100.00% (353) | transcriptional regulatory protein AraC/XylS-family |
| M. gilvum PYR-GCK | Mflv_4594 | - | 6e-10 | 33.33% (126) | helix-turn-helix domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3997c | - | 1e-91 | 52.54% (335) | transcriptional regulatory protein |
| M. marinum M | MMAR_5276 | - | 1e-144 | 76.12% (335) | AraC/XylS family transcriptional regulator |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3718 | - | 1e-07 | 26.25% (320) | PUTATIVE putative aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_4350 | - | 1e-143 | 75.52% (335) | AraC/XylS family transcriptional regulator |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3736|M.tuberculosis_H37Rv MSVVRGTALANYP----------SLVAGLGGDPATLLRAAGVRDQDVGNY
Mb3763|M.bovis_AF2122/97 MSVVRGTALANYP----------SLVAGLGGDPATLLRAAGVRDQDVGNY
MMAR_5276|M.marinum_M MSVVRGTGLSNYP----------NLVSELGGDPAALLRAAGVREQDVGNY
MUL_4350|M.ulcerans_Agy99 MSVVRGTGLSNYP----------NLVSELGGDPAALLRAAGVREQDVGNY
MAB_3997c|M.abscessus_ATCC_199 MAVIRGSALTNYH----------ELVAELGGDGSRLLAGARVSPTDAGSY
Mflv_4594|M.gilvum_PYR-GCK MDWAQGARSVKFSNAGVPPVAFVQMLESQALDPDAVARLRTIMAREGTDE
TH_3718|M.thermoresistible__bu VAAADLIDTA----------------VEAGIPADRCLRGTWLTRSDLAAA
: . : :
Rv3736|M.tuberculosis_H37Rv DAFISIRAAI-----RAIESAAAVTATMDFGRRLAQRQGIEILGPVGVAA
Mb3763|M.bovis_AF2122/97 DAFISIRAAI-----RAIESAAAVTATMDFGRRLAQRQGIEILGPVGVAA
MMAR_5276|M.marinum_M DAFIPVRAVI-----RAIETAAAATGTHDFGRQLAQRQGIEILGPVGVAA
MUL_4350|M.ulcerans_Agy99 DAFIPVRAVI-----RAIETAAAATGTHDFGRQLAQRQGIEILGPVGVAA
MAB_3997c|M.abscessus_ATCC_199 ERFISLPNGA-----RALEATAAALNAPDFGRQLARRQGIEILGPVGLAA
Mflv_4594|M.gilvum_PYR-GCK ATLMQHDVQAPLRWFRDLYPDLDVDRATLLGFSFAGQAQLTSFGPLSVPL
TH_3718|M.thermoresistible__bu DRLITAEQELR----IVRNVLAATEHPTALAGSAGARYQLPRAGFLGFAL
:: . . :. . : : * :...
Rv3736|M.tuberculosis_H37Rv RTAATVGDALAIFNTFMAAYSPVIAIRITPLAG-QRSFIALEFLLDEPAS
Mb3763|M.bovis_AF2122/97 RTAATVGDALAIFNTFMAAYSPVIAIRITPLAG-QRSFIALEFLLDEPAS
MMAR_5276|M.marinum_M RTAATVADALMIFHTFMAAYSPAIHIEITPLAHTQRSFVAIEIVPDDPIP
MUL_4350|M.ulcerans_Agy99 RTAATVADALMIFHTFMAAYSPAIHIEITPLARTQRSVVAIEIVPDDPIP
MAB_3997c|M.abscessus_ATCC_199 RTAATVADAFAILEKFMGAYCPVISARVTDHRDPALCRFEFEYLLNPAPP
Mflv_4594|M.gilvum_PYR-GCK VSAGSVAEIVELLT-----YLPLITTAINAQFRPNDQGLTVGLWGHTGDR
TH_3718|M.thermoresistible__bu LSSNTLGDAIRVGIR----FWRLTSVFERVTLEVNRQTTAIVLDDRDVPA
:: ::.: . : : .
Rv3736|M.tuberculosis_H37Rv YPQTMELALG-VALGVIRLLLGADYAPLAVHLPHDPLT--PEAFYLQYFG
Mb3763|M.bovis_AF2122/97 YPQTMELALG-VALGVIRLLLGADYAPLAVHLPHDPLT--PEAFYLQYFG
MMAR_5276|M.marinum_M CPHTLELALG-VSLGVFRLLMGADYTPLAVHLPHDPLT--PPTTYVRYFE
MUL_4350|M.ulcerans_Agy99 CPHTLELALG-VSLGVFRLLMGADYTPLAVHLPHDPLT--PPTTYVRYFE
MAB_3997c|M.abscessus_ATCC_199 QAQAVELSLG-VTLRVLHHFLGAGYRPVSVHLPHQALT--PASAYQRYFG
Mflv_4594|M.gilvum_PYR-GCK ALDCLAVTYTGSALLRLLDMLVSDALTVTLHLSWSAPVSLNKLAAEMVLA
TH_3718|M.thermoresistible__bu DVRQFLVERDAATMVGVTPALLGGPLPDGVRMSLRRRPN-GDAAVEELVD
. : :: . : .. . :::. .
Rv3736|M.tuberculosis_H37Rv CRPYFAERVGGFTMRTADLSRPLNR-DDVAHRVVVDYLS-SITPLGEGIV
Mb3763|M.bovis_AF2122/97 CRPYFAERVGGFTMRTADLSRPLNR-DDVAHRVVVDYLS-SITPLGEGIV
MMAR_5276|M.marinum_M CTPHFAERRSGFTVRSTDLVRPLHR-DELAHRAVVDYLS-SITPLGAGIV
MUL_4350|M.ulcerans_Agy99 CTPHFAERRSGFTVRSTDLVRPLHR-DELAHRAVVDYLS-SITPLGAGIV
MAB_3997c|M.abscessus_ATCC_199 CPPFFCEPVGGFTLRATDMQKALPK-DNLAHQTAVDYLTGTHASRKPDSS
Mflv_4594|M.gilvum_PYR-GCK GRLFFDAPMSYLHVPVNALNEVCRFSDPLAYRLAVAELRRTLDEQSGATS
TH_3718|M.thermoresistible__bu VS--YGADRNAITFPTALLDRPLAAANPAVAAQCIAQCDELLARHQDEPT
: . : . : . : . :
Rv3736|M.tuberculosis_H37Rv ESVRTIVRQLLPTGAA-TLNVVAEQFHLHPKTLQRRLAEENTTFVILVDR
Mb3763|M.bovis_AF2122/97 ESVRTIVRQLLPTGAA-TLNVVAEQFHLHPKTLQRRLAEENTTFVILVDR
MMAR_5276|M.marinum_M ESVRTMARQLLPTGAA-TLEVVAAQFHLHPKTLQRRLADESTTFAALIDE
MUL_4350|M.ulcerans_Agy99 ESVRTMARQLLPTGAT-TLEVVAAQFHLHPKTLQRRLADESTTFAALIDE
MAB_3997c|M.abscessus_ATCC_199 QLVRILIRQLLPTGAI-GLGDIALHLGVHPKTLQRRLRAEGMTFAELVDQ
Mflv_4594|M.gilvum_PYR-GCK FSKKVRRLLDEDPGQR-SCQRVADELSVSTSTLKRRLAEEGTTFRELRQS
TH_3718|M.thermoresistible__bu VASRVRRRLARDPGAVPLMRTLATEMGFTERTLRRRLAREGTGYRSLIDE
: .* :* .: . **:*** *. : * :
Rv3736|M.tuberculosis_H37Rv VRKDVADRYLRTTGIGLTHLARELGYAEQSVLTRSCKRWFGTGPAAYRNQ
Mb3763|M.bovis_AF2122/97 VRKDVADRYLRTTGIGLTHLARELGYAEQSVLTRSCKRWFGTGPAAYRNQ
MMAR_5276|M.marinum_M VRKETADRYLRTTAMSLSHLARELGYAEQSVLTRSCKRWFGIGPAAYRAK
MUL_4350|M.ulcerans_Agy99 VRKETADRYLRTTAMSLSHLARELGYAEQSVLTRSCKRWFGIGPAAYRAK
MAB_3997c|M.abscessus_ATCC_199 IRREAAERLLSDTDLSLDHLSRQLGYAEQSVFTRSCKRWFGTTPSAYRSD
Mflv_4594|M.gilvum_PYR-GCK CLRESAMMLLITRSMSASQIATELGYGDLANFSHAFKRWTGRSPSEYRRS
TH_3718|M.thermoresistible__bu VRGARAADLLSG-GATVKQVAQQLGYSEPAAFHHAFVRWHALPPARFRRA
* * ::: :***.: : : :: ** . *: :*
Rv3736|M.tuberculosis_H37Rv ARLQTTVSAPGSGRGPNPGNVSVSC
Mb3763|M.bovis_AF2122/97 ARLQTTVSAPGSGRGPNPGNVSVSC
MMAR_5276|M.marinum_M TRVRATPRRR---------------
MUL_4350|M.ulcerans_Agy99 TRVRATPRRR---------------
MAB_3997c|M.abscessus_ATCC_199 RRRA---------------------
Mflv_4594|M.gilvum_PYR-GCK QR-----------------------
TH_3718|M.thermoresistible__bu DVR----------------------