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M. abscessus ATCC 19977 MAB_2050 (-)

annotation: putative HTH-type transcriptional regulator AraC
coordinates: 2050944 - 2051948
length: 334

VKLDDSGMPALAFLQMLDSEALGHDASIALRSIMVREHVTESMLVGRDAQVPLRWFREIYSDFDCDQGTR
LGFAFAEHAKLTSFGALSVPLVSAGSVAEVVELLAYLPVITTALSPSFHSTERGLTIGLTGRTGDAGLNC
LAVTYGGLALLRLLDMLAGAVPNIELHLSHSAPESWVLHDEVLAGRIFFDAPSSFVHVPAATLEEVCRFS
DPVAYRIAVTDLQRTLDQRRDTSVSEKVRDLLEKDPGKTNISRTAGELSISPSTLKRRLREEGTTFRELR
QSFLQERAILRILDRSVSVSEIAAELGYADLTNFTHAFKRWTGRSPRHFRKTRD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2050--100% (334)putative HTH-type transcriptional regulator AraC
M. abscessus ATCC 19977MAB_3997c-4e-1527.74% (274) transcriptional regulatory protein
M. abscessus ATCC 19977MAB_0715c-1e-1341.18% (85) putative HTH-type transcriptional regulator AraC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1430-5e-1625.63% (277) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_4594-1e-11160.42% (336) helix-turn-helix domain-containing protein
M. tuberculosis H37RvRv1395-6e-1625.63% (277) transcriptional regulatory protein
M. leprae Br4923-----
M. marinum MMMAR_3156-1e-11765.66% (332) AraC/XylS family transcriptional regulator
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_3718-5e-1430.61% (147) PUTATIVE putative aldehyde dehydrogenase
M. ulcerans Agy99MUL_4350-3e-1427.38% (325) AraC/XylS family transcriptional regulator
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1430|M.bovis_AF2122/97            --MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDP
Rv1395|M.tuberculosis_H37Rv         --MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDP
TH_3718|M.thermoresistible__bu      ----------------VAAADLIDTAVEAGIPADRCLRGTWLTRSDLAAA
Mflv_4594|M.gilvum_PYR-GCK          MDWAQGARSVKFSNAGVPPVAFVQMLESQALDPDAVARLRTIMAREGTDE
MMAR_3156|M.marinum_M               ---------MNPNDAGVPPLAFVQMLESPAFDPDAVARLRNIMAREGTDE
MAB_2050|M.abscessus_ATCC_1997      ---------MKLDDSGMPALAFLQMLDSEALGHDASIALRSIMVREHVTE
MUL_4350|M.ulcerans_Agy99           ----------MSVVRGTGLSNYPNLVSELGGDPAALLRAAGVREQDVGNY
                                                           :   . .           :   :    

Mb1430|M.bovis_AF2122/97            DAVVG--ALDEITAVRRLLARLPDDAG--IGIDVGSRFALTHFGLFGFAV
Rv1395|M.tuberculosis_H37Rv         DAVVG--ALDEITAVRRLLARLPDDAG--IGIDVGSRFALTHFGLFGFAV
TH_3718|M.thermoresistible__bu      DRLIT--AEQELRIVRNVLAATEHPTA--LAGSAGARYQLPRAGFLGFAL
Mflv_4594|M.gilvum_PYR-GCK          ATLMQHDVQAPLRWFRDLYPDLDVDRATLLGFSFAGQAQLTSFGPLSVPL
MMAR_3156|M.marinum_M               ATLIQRDIQAPLRWFREAYPGLDIDQATLLGFALAEQAQLTSFGPLSVPL
MAB_2050|M.abscessus_ATCC_1997      SMLVGRDAQVPLRWFREIYSDFDCDQGTRLGFAFAEHAKLTSFGALSVPL
MUL_4350|M.ulcerans_Agy99           DAFIP-----VRAVIRAIETAAAATGTHDFGRQLAQRQGIEILGPVGVAA
                                      .:          .*   .         :.   . :  :   * .... 

Mb1430|M.bovis_AF2122/97            MSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRG
Rv1395|M.tuberculosis_H37Rv         MSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRG
TH_3718|M.thermoresistible__bu      LSSNTLGDAIRVGIRFWRLTSVFERVTLEVNRQTTAIVLDDRDVPADVRQ
Mflv_4594|M.gilvum_PYR-GCK          VSAGSVAEIVEL-LTYLPLITTAINAQFRPNDQGLTVGLWGHTGDRALDC
MMAR_3156|M.marinum_M               VSAGSVAEIVEL-LTYLPLITTAVKAQFHPDDQGLTVGLWGHTSDRALDC
MAB_2050|M.abscessus_ATCC_1997      VSAGSVAEVVEL-LAYLPVITTALSPSFHSTERGLTIGLTGRTGDAGLNC
MUL_4350|M.ulcerans_Agy99           RTAATVADALMIFHTFMAAYSPAIHIEITPLARTQRSVVAIEIVPDDP--
                                     :. :: : : :   :    :      :          :           

Mb1430|M.bovis_AF2122/97            FFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVH
Rv1395|M.tuberculosis_H37Rv         FFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVH
TH_3718|M.thermoresistible__bu      FLVERDAATMVGVTP--AL-LGGPLPDGVRMSLRRRPNGDAAVEELV---
Mflv_4594|M.gilvum_PYR-GCK          LAVTYTGSALLRLLD---MLVSDALTVTLHLSWSAPVSLNKLAAEMVLAG
MMAR_3156|M.marinum_M               LAVTYAGLALLRLLD---MLVRAAPTLTLHLSWPAPAALKDREDDLT-AG
MAB_2050|M.abscessus_ATCC_1997      LAVTYGGLALLRLLD---MLAGAVPNIELHLSHSAPESW--VLHDEVLAG
MUL_4350|M.ulcerans_Agy99           IPCPHTLELALGVSLGVFRLLMGADYTPLAVHLPHDPLTPPTTYVRYFEC
                                    :         :                 :                     

Mb1430|M.bovis_AF2122/97            DVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGI
Rv1395|M.tuberculosis_H37Rv         DVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGI
TH_3718|M.thermoresistible__bu      DVSYGADRNAITFPTALLDRPLAAANPAVAAQCIAQCDELLARHQDEPTV
Mflv_4594|M.gilvum_PYR-GCK          RLFFDAPMSYLHVPVNALNEVCRFSDPLAYRLAVAELRRTLDEQSGATSF
MMAR_3156|M.marinum_M               RLFFDAPMSFLHVPADTLNEVCRFSDPVAYRLAIVDLQRTLDQRSETTSF
MAB_2050|M.abscessus_ATCC_1997      RIFFDAPSSFVHVPAATLEEVCRFSDPVAYRIAVTDLQRTLDQRR-DTSV
MUL_4350|M.ulcerans_Agy99           TPHFAERRSGFTVRSTDLVRPLHRDELAHRAVVDYLSSITPLGAGIVESV
                                       :    . . .    : .     :                       .

Mb1430|M.bovis_AF2122/97            TALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEA
Rv1395|M.tuberculosis_H37Rv         TALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEA
TH_3718|M.thermoresistible__bu      ASRVRRRLARDPGAVPLMRTLATEMGFTERTLRRRLAREGTGYRSLIDEV
Mflv_4594|M.gilvum_PYR-GCK          SKKVRRLLDEDPGQR-SCQRVADELSVSTSTLKRRLAEEGTTFRELRQSC
MMAR_3156|M.marinum_M               SEKVRRLLQKEPGRR-SKHWFAHELSMSTSTLKRRLSEEETTFRELRQAF
MAB_2050|M.abscessus_ATCC_1997      SEKVRDLLEKDPGKT-NISRTAGELSISPSTLKRRLREEGTTFRELRQSF
MUL_4350|M.ulcerans_Agy99           RTMARQLLPTG---ATTLEVVAAQFHLHPKTLQRRLADESTTFAALIDEV
                                       .*  *             * :: .   **:***  * * :  *    

Mb1430|M.bovis_AF2122/97            RSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
Rv1395|M.tuberculosis_H37Rv         RSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
TH_3718|M.thermoresistible__bu      RGARAADLLS-GGATVKQVAQQLGYSEPAAFHHAFVRWHALPPARFRRAD
Mflv_4594|M.gilvum_PYR-GCK          LRESAMMLLITRSMSASQIATELGYGDLANFSHAFKRWTGRSPSEYRRSQ
MMAR_3156|M.marinum_M               LRERAMLQLLDRSLSVSEIATDLGYSDLANFSHAFKRWTGRSPSEFRLSP
MAB_2050|M.abscessus_ATCC_1997      LQERAILRILDRSVSVSEIAAELGYADLTNFTHAFKRWTGRSPRHFRKTR
MUL_4350|M.ulcerans_Agy99           RKETADRYLRTTAMSLSHLARELGYAEQSVLTRSCKRWFGIGPAAYRAKT
                                        *   :   . : ..::  *** : : : ::  ** .  *  :    

Mb1430|M.bovis_AF2122/97            ---------
Rv1395|M.tuberculosis_H37Rv         ---------
TH_3718|M.thermoresistible__bu      VR-------
Mflv_4594|M.gilvum_PYR-GCK          R--------
MMAR_3156|M.marinum_M               H--------
MAB_2050|M.abscessus_ATCC_1997      D--------
MUL_4350|M.ulcerans_Agy99           RVRATPRRR