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TVANSESETPDAGYSRGLSARTVQMIAIGGAIGTGLFYGAGGAIEKAGPGLILTYLVAGLAIFVIMRALG ELLVYRPVSGSISEYAEEFMGRFAGFANGWTYWAVWATTCMAEITVAGVYIQRWWPGIPQWVTALVVLLI LFGANLISVKIFGEAEFWFSMIKVTAILGMIIIGVGVLLPISGLGPETGPSVANLWNDGGVFPTGFSQAL LSLQIVVFAYVGVELVGVTAGEAENPKVTLRKAINTLPFRIGLFYVGALIVILSIQGWRNYHKGESPFVA VFEYLNIPQAANIVNFILLTAALSSCNSGIYSTGRMVRSLAQRGDAPAGLQALSSRHVPMLAICFSALAM GIGVFVNWLSPDKAFAYITSVSTIGIIFVWGSILVSHMIYRKRVADGLLPASDYKLPGAPVTNILALGFL ALVVLLLFFTEDGRTAILVGVVWFIIVVLGYFVHHGEPAHRETQDA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3866c | - | - | 100% (467) | putative amino acid permease |
| M. abscessus ATCC 19977 | MAB_2535 | - | e-115 | 44.34% (442) | amino acid transporter |
| M. abscessus ATCC 19977 | MAB_2914 | - | e-105 | 42.92% (459) | L-asparagine permease 1 (L-asparagine transport) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1730c | cycA | 1e-99 | 41.43% (449) | D-serine/alanine/glycine transporter protein CycA |
| M. gilvum PYR-GCK | Mflv_1998 | - | 2e-82 | 37.33% (434) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv1704c | cycA | 3e-99 | 41.43% (449) | D-serine/alanine/glycine transporter protein CycA |
| M. leprae Br4923 | MLBr_01305 | ansP2 | 6e-93 | 41.65% (425) | putative L-asparagine permease |
| M. marinum M | MMAR_1093 | cycA | 1e-102 | 43.02% (451) | D-serine/D-alanine/glycine transporter, CycA |
| M. avium 104 | MAV_4626 | - | 4e-80 | 36.53% (438) | gaba permease |
| M. smegmatis MC2 155 | MSMEG_3587 | - | 1e-102 | 41.08% (465) | D-serine/D-alanine/glycine transporter |
| M. thermoresistible (build 8) | TH_3126 | - | 2e-13 | 24.79% (238) | PUTATIVE putative amino acid permease-associated region |
| M. ulcerans Agy99 | MUL_0851 | cycA | 1e-101 | 42.64% (455) | D-serine/D-alanine/glycine transporter, CycA |
| M. vanbaalenii PYR-1 | Mvan_3196 | - | 2e-18 | 22.50% (440) | ethanolamine transproter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1730c|M.bovis_AF2122/97 ---------MPDDIAAADPTDTQPHLRRDLANRHIQLIAIGGA----IGT
Rv1704c|M.tuberculosis_H37Rv ---------MPDDIAAADPTDTQPHLRRDLANRHIQLIAIGGA----IGT
MMAR_1093|M.marinum_M ---------MPEDVATCQPTESTPHLHRGLSNRHIQLIAIGGA----IGT
MUL_0851|M.ulcerans_Agy99 --------MMPEDVATCQHTESTPHLHRGLSNRHIQLIAIGGA----IGT
MSMEG_3587|M.smegmatis_MC2_155 --------------MSEQTLPEAEHLSRQLSNRHIQLIAIGGA----IGT
MAB_3866c|M.abscessus_ATCC_199 -----------MTVANSESETPDAGYSRGLSARTVQMIAIGGA----IGT
Mflv_1998|M.gilvum_PYR-GCK -------------------MSAAPTLKKALNQRQLTMIAIGGV----IGA
MAV_4626|M.avium_104 -------------------MAGTSQLRQGLSQRQLSMIALGGV----IGA
MLBr_01305|M.leprae_Br4923 MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIGGA----IGT
Mvan_3196|M.vanbaalenii_PYR-1 -MSGEAHSTHTTRGVEAHRESDAYLQKRQLKKGSAGWILLAGLGISYVVS
TH_3126|M.thermoresistible__bu -------------------------LPRRLGTLDAVTIGLGAM----IGA
: * * :.. : :
Mb1730c|M.bovis_AF2122/97 GLFMGSGRTISLAGP-AVMVVYGIIGFFVFFVLRAMGELLLSNLNYKSFV
Rv1704c|M.tuberculosis_H37Rv GLFMGSGRTISLAGP-AVMVVYGIIGFFVFFVLRAMGELLLSNLNYKSFV
MMAR_1093|M.marinum_M GLFMGSGRTISLAGP-AVIVVYAVIGFFVFFVLRAMGELLLSNLNYKSFV
MUL_0851|M.ulcerans_Agy99 GLFMGSGRTISLAGP-AVIVVYAVIGFFVFFVLRAMGELLLSNLNYKSFV
MSMEG_3587|M.smegmatis_MC2_155 GLFMGSGKTVSLAGP-SVIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFA
MAB_3866c|M.abscessus_ATCC_199 GLFYGAGGAIEKAGP-GLILTYLVAGLAIFVIMRALGELLVYRPVSGSIS
Mflv_1998|M.gilvum_PYR-GCK GLFVGSGVVIADTGP-GAFLTYGMAGVLIIMVMRMLAEMAVANPSTGSFA
MAV_4626|M.avium_104 GLFVGSGVVIKDTGP-AAFLTYALCGLLIVLVMRMLGEMAAANPSTGSFA
MLBr_01305|M.leprae_Br4923 GLFLGAGGRLAKAGP-GLFLVYAVCGVFVFLILRALGELVLHRPSSGSFV
Mvan_3196|M.vanbaalenii_PYR-1 GDYSGWNFGLGQGGFGGLAIAAVVIAAMYLAMVLGMAEMSSALPAAGGGY
TH_3126|M.thermoresistible__bu GIFVALGPAAAAAGP-WLLAGLGIAAAVAYCNATASARLAARYPQSGGTY
* : . . * : . ..: .
Mb1730c|M.bovis_AF2122/97 DFAADLLGPAAGFFVGWSYWFAWVVTGIADLVAITGYARFWWP--GLPIW
Rv1704c|M.tuberculosis_H37Rv DFAADLRGPAAGFFVGWSYWFAWVVTGIADLVAITGYARFWWP--GLPIW
MMAR_1093|M.marinum_M DCAADLLGPAAGYFMGWSYWFAWIVAGIADLVAITGYSKFWWP--DVPTW
MUL_0851|M.ulcerans_Agy99 DCAADLLGPAAGYFMGWSYWFAWIVAGIADLVAITGYSKFWWP--DVPTW
MSMEG_3587|M.smegmatis_MC2_155 DFAADLLGPWAGFFTGWTYWFCWIVTGVAEVVAIAGYVAFWWP--DLPLW
MAB_3866c|M.abscessus_ATCC_199 EYAEEFMGRFAGFANGWTYWAVWATTCMAEITVAGVYIQRWWP--GIPQW
Mflv_1998|M.gilvum_PYR-GCK DYSRNALGHWAGFSVGWLYWYFWVIVVGFEAIAGAKIVQYW---MDVPLW
MAV_4626|M.avium_104 DYAAAALGRWAGFSVAWLYWYFWVIVVGFEAVAGGKVLNYW---FHAPLW
MLBr_01305|M.leprae_Br4923 SYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHRWTIFTALPQW
Mvan_3196|M.vanbaalenii_PYR-1 TFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVESLGLFGITDGW
TH_3126|M.thermoresistible__bu VYGRERLGAFWGYTAGFSFVVGKTASCAAMALTIGFYLWPG------HAH
. * .: .
Mb1730c|M.bovis_AF2122/97 VPALVTVALILAVNLFSVRHFGELEFWFALIKVAAIVCLIAVGA--ILVA
Rv1704c|M.tuberculosis_H37Rv VPALVTVALILAVNLFSVRHFGELEFWFALIKVAAIVCLIAVGA--ILVA
MMAR_1093|M.marinum_M APALVTIAVMLSINMFGVSKFGETEFWFALIKVAAILCLITVGA--ILVI
MUL_0851|M.ulcerans_Agy99 APALVTIAVMLSINMFGVSKFGGTEFWFALIKVAAILCLITVGA--ILVI
MSMEG_3587|M.smegmatis_MC2_155 IPALVTVAVLITLNLATVRAFGETEFWFAMIKIVAILALIVVGL--VMVL
MAB_3866c|M.abscessus_ATCC_199 VTALVVLLILFGANLISVKIFGEAEFWFSMIKVTAILGMIIIGVGVLLPI
Mflv_1998|M.gilvum_PYR-GCK LSALIFMVLMTATNLFSVASYGEFEFWFAGIKVAAIIAFIAVGA---AFV
MAV_4626|M.avium_104 VLSLGLMLLMTATNLFSVSSFGEFEFWFAGIKVATIVIFLVVGA---AYV
MLBr_01305|M.leprae_Br4923 TLALLALAVVLVMNLISVEWFGELEFWAALIKVCALMAFLVVGT---IFL
Mvan_3196|M.vanbaalenii_PYR-1 WVYLAAYAIFIGIHLSGVGEALKVMFVITAIALVGLVVFAVAAIP-----
TH_3126|M.thermoresistible__bu AIAVAAVVALTALTYLGIEKSALLTRLVVAGVLGVLTAVVVLVLG-----
: . : : : .
Mb1730c|M.bovis_AF2122/97 TNFVSPHGVHATIENLWNDNGFFPTGFLGVVSGFQIAFFAYIGVELVGTA
Rv1704c|M.tuberculosis_H37Rv TNFVSPHGVHATIENLWNDNGFFPTGFLGVVSGFQIAFFAYIGVELVGTA
MMAR_1093|M.marinum_M TGFTSPDGDRAALANLWNDGGFFPTGFVGLASGFQIAFFAYIGVELVGAA
MUL_0851|M.ulcerans_Agy99 TGFTSPDGDRAALANLWNDGGFFPTGFVGLASGFQIAFFAYIGVELVGAA
MSMEG_3587|M.smegmatis_MC2_155 SHFRAPGGAVASLSNLWDDGGFFPTGPMGFVAGFQIATFAFVGIELVGTT
MAB_3866c|M.abscessus_ATCC_199 SGLGPETG--PSVANLWNDGGVFPTGFSQALLSLQIVVFAYVGVELVGVT
Mflv_1998|M.gilvum_PYR-GCK LG--LWPGKGADFSNLTSHGGFMPLGFGAITVGIVTVIFSMVGAEIATIA
MAV_4626|M.avium_104 IG--LVPGHHDGLTNLVSHGGFFPRGVGAVFAAIVVVIFSMVGAEIVTVA
MLBr_01305|M.leprae_Br4923 GGRYPVDGHNTGLSLWTSHGGLFPTGVAPLIVVSSGVMFAYAAVELVGTA
Mvan_3196|M.vanbaalenii_PYR-1 -HFDSTNLTDIAVTDAAGASALLPFGLLGIWAAIPFAIWFFLAIEGVPLA
TH_3126|M.thermoresistible__bu ----------FGAPAGRVAGGGTDIGAGAVLQSAALLFFAFAGYARIATL
.. * : .
Mb1730c|M.bovis_AF2122/97 AAETADPRRTLPRAINAVPLRVAVFYIGALLAILAVVPWRQFASGESPFV
Rv1704c|M.tuberculosis_H37Rv AAETADPRRTLPRAINAVPLRVAVFYIGALLAILAVVPWRQFASGESPFV
MMAR_1093|M.marinum_M AAEAADPSHTLPRAINAVPLRVAIFYIGALLAILSVVPWRRFASGESPFV
MUL_0851|M.ulcerans_Agy99 AAEAADPSHTLPRAINAVPLRVAIFYIGALLAILSVVPWRRFASGESPFV
MSMEG_3587|M.smegmatis_MC2_155 AAEARDPERNLPRAVNSIPVRVMLFYVAALVIIIAVTPWREISPDRSPFV
MAB_3866c|M.abscessus_ATCC_199 AGEAENPKVTLRKAINTLPFRIGLFYVGALIVILSIQGWRNYHKGESPFV
Mflv_1998|M.gilvum_PYR-GCK AAESQDPERAVAKAANSVILRILIFYVGAVLLLVLIVPWNDESVSASPFV
MAV_4626|M.avium_104 AAESRDPRRAVQKATRSVVTRIGIFFVGSVFLLVAILPWDSVELGASPYV
MLBr_01305|M.leprae_Br4923 AGETVEPKKIMPRAINSVIARIAIFYVGSVILLALLLPYSAFKASESPFV
Mvan_3196|M.vanbaalenii_PYR-1 AEETAEPERNVPKGIIAGMAVLLVTCVTVLVLTTGAGGAAAMSESGNPLV
TH_3126|M.thermoresistible__bu GEEVRDPARTIRRAIPLALGITLTVYGAVTAAVLVALGSAGLARSPAPVA
. * :* : :. . * .
Mb1730c|M.bovis_AF2122/97 TMFSLAGLAAAASVVNFVVVTAAASSANSGFFSTGRMLFGLADEGHAPAA
Rv1704c|M.tuberculosis_H37Rv TMFSLAGLAAAASVVNFVVVTAAASSANSGFFSTGRMLFGLADEGHAPAA
MMAR_1093|M.marinum_M TMFALAGLAAAASVVNFVVITSAASSANSGVFSTGRMLYGLADEGSAPGI
MUL_0851|M.ulcerans_Agy99 TMFALAGLAAAASVVNFVVITSAASSANSGVFSTGRMLYGLADEGSAPGI
MSMEG_3587|M.smegmatis_MC2_155 AMFSLAGLGIAASVVNFVVLTSAASSANSGIYSTSRMVYGLSCGGDAPAS
MAB_3866c|M.abscessus_ATCC_199 AVFEYLNIPQAANIVNFILLTAALSSCNSGIYSTGRMVRSLAQRGDAPAG
Mflv_1998|M.gilvum_PYR-GCK AAFNAMGIPYADHVMNAVVLTAVLSCLNSGMYTASRMLFVLAARREAPAA
MAV_4626|M.avium_104 AALKHLGLAGADQVMNAVVLTAVLSCLNSGLYTASRMLFVLAERGEAPAR
MLBr_01305|M.leprae_Br4923 TFFSKVGFYGAGDLMNIVVLTAALSSLNAGLYATGRVMHSIAINGSGPKF
Mvan_3196|M.vanbaalenii_PYR-1 EALGDS---GWAKVVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPTV
TH_3126|M.thermoresistible__bu DAVTAAXXHGRQQPFGELPGAEEVDRGHPQRIPDARRHPGHVEHRSSPTT
. .. : : . . .* *
Mb1730c|M.bovis_AF2122/97 FHQLNRGGVPAPALLLTAPLLLTSIPLLYAGRSVIGAFTLVTTVSSLLFM
Rv1704c|M.tuberculosis_H37Rv FHQLNRGGVPAPALLLTAPLLLTSIPLLYAGRSVIGAFTLVTTVSSLLFM
MMAR_1093|M.marinum_M FGRLNRRGVPAPALILTAALLLSAIPLLYAGGSVIGAFTLITTISSLLFM
MUL_0851|M.ulcerans_Agy99 FGRLNSRGVPAPALILTAALLLSAIPLLYAGGSVTGAFTLITTISSLLFM
MSMEG_3587|M.smegmatis_MC2_155 FGRLTSRRVPANALFLSGVVLLSSVVMVAAGDSIIAAFTLVTTISSLCFM
MAB_3866c|M.abscessus_ATCC_199 LQALSSRHVPMLAICFSALAMG--IGVFVNWLSPDKAFAYITSVSTIGII
Mflv_1998|M.gilvum_PYR-GCK LVKVTNRGVPANAILASSVVGFLCVIAAAVSPD--TIFAFLLNSSGAIIL
MAV_4626|M.avium_104 LVRLSGRGVPHIAILCSSAVGFLCVVMARVAPN--TVFLFLLNSSGAIIL
MLBr_01305|M.leprae_Br4923 TARMSKNGVPYGGILLAAVICLCGVALNAFNPG--QAFEIVLSVAALGII
Mvan_3196|M.vanbaalenii_PYR-1 LSVTNSRKAPTLALIVPGVIGFLLSLIG--------QGALLLNMAVFGAA
TH_3126|M.thermoresistible__bu CAPRP-----------------------------------------LTWR
Mb1730c|M.bovis_AF2122/97 FVWAMIIISYLVYRRRHPQ-RHTDSVYKMPGGVVMCWAVLVFFAFVIWTL
Rv1704c|M.tuberculosis_H37Rv FVWAMIIISYLVYRRRHPQ-RHTDSVYKMPGGVVMCWAVLVFFAFVIWTL
MMAR_1093|M.marinum_M FVWTMIVISYLVYRRRHAQ-RHADSAYKMPGGVVMCWAILGFFVFVIWTL
MUL_0851|M.ulcerans_Agy99 FVWTMIVISYLVYRRRHAQ-RHADSAYKMPGGVVMCWAILGFFVFVIWTL
MSMEG_3587|M.smegmatis_MC2_155 FIWTIILSSYLVYRRRRPQ-QHSASPFKMPGGVVMCWVVLAFFVFLVWAF
MAB_3866c|M.abscessus_ATCC_199 FVWGSILVSHMIYRKRVADGLLPASDYKLPGAPVTNILALGFLALVVLLL
Mflv_1998|M.gilvum_PYR-GCK FVYLLIAISQIVLRYRTPD---SKLRVKMWLFPVLSGLTALGILAILVQM
MAV_4626|M.avium_104 FVYWLIALSQIVLRRRTPA---ERLSVKMWFFPVLSVLTLAGITAVLVQM
MLBr_01305|M.leprae_Br4923 AGWGTIVLCQLRLHKMAKAGIMRRPRFRMPLAPYSGYLTLAFLFAVLVVM
Mvan_3196|M.vanbaalenii_PYR-1 LSYVLMMVSHIVLRRREPD---MPRPYRTPGGVVTTGFALVIAVLAVIAT
TH_3126|M.thermoresistible__bu TTWAPMPDPQPVTTTRRPS-------------------------------
: :
Mb1730c|M.bovis_AF2122/97 T----TETETATALAWFPLWFVLLAVGWLVTQRRQSRRSFGFHCQVVGVR
Rv1704c|M.tuberculosis_H37Rv T----TETETATALAWFPLWFVLLAVGWLVTQRRQSRRSFGFHCQVVGVR
MMAR_1093|M.marinum_M T----TETETATALVWFPLWFVILGIGWALVRRRP------------GHL
MUL_0851|M.ulcerans_Agy99 TTETETETETATALVWFPLWFVILGIGWALVRRRP------------GHL
MSMEG_3587|M.smegmatis_MC2_155 T----QKSDTLQALLVTPAWFVVLGIAWAFLRRRL------------GHK
MAB_3866c|M.abscessus_ATCC_199 F----FTEDGRTAILVGVVWFIIVVLGYFVHHGEP------------AHR
Mflv_1998|M.gilvum_PYR-GCK FIDTALRSQLVLSLLSWAVVIALFAANKWFVKKRPAEGDSGAPTGPPHRV
MAV_4626|M.avium_104 AFDATARSQLWLSLLSWAVVVALY-----FVAR--SRGRVAAR-------
MLBr_01305|M.leprae_Br4923 AFDKPIGTWTVASLIVIVPALIAG----WYSIRKRVMTIARERMGYTGPF
Mvan_3196|M.vanbaalenii_PYR-1 FLVDSVAALCCLVVFAAFMAYFGIYSRHHLVANSPD-----------EEF
TH_3126|M.thermoresistible__bu --------------------------------------------------
Mb1730c|M.bovis_AF2122/97 QQLGRGMARLAMKIHARPKLRSAVVVEPVSAGEPGARRSAKSVRKLASDD
Rv1704c|M.tuberculosis_H37Rv QQLGRGMARLAMKIHARPKLRSAVVVEPVSAGEPGARRSAKSVRKLASDD
MMAR_1093|M.marinum_M EQYHR----FQAEMNG--------TTEGILPPDASART------------
MUL_0851|M.ulcerans_Agy99 EQYHR----FQAEMNG--------TAEGVLPPDASART------------
MSMEG_3587|M.smegmatis_MC2_155 AREAA----FRAALEA----------ESADSAD-----------------
MAB_3866c|M.abscessus_ATCC_199 ETQDA---------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK LVLANRTVDSDELLAELSRIGADQTAEYLVVVPASAVDTGAAATHGPRDV
MAV_4626|M.avium_104 --------------------------------------------------
MLBr_01305|M.leprae_Br4923 PAIANPPVQPSERSHSQNP-------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 AALAAAEGELK---------------------------------------
TH_3126|M.thermoresistible__bu --------------------------------------------------
Mb1730c|M.bovis_AF2122/97 SQSAHCPVAVVGLADGGRDPQYHHDGPDR---------------------
Rv1704c|M.tuberculosis_H37Rv SQSAHCPVAVVGLADGGRDPQYHHDGPDR---------------------
MMAR_1093|M.marinum_M --------------------------------------------------
MUL_0851|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_3587|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3866c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK TEATQEAATARLESTLAALRGKNLTVQGELGDYRPLRALDHAVAEFGPDQ
MAV_4626|M.avium_104 --------------------------------------------------
MLBr_01305|M.leprae_Br4923 --------------------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3126|M.thermoresistible__bu --------------------------------------------------
Mb1730c|M.bovis_AF2122/97 ---------------------------------------------
Rv1704c|M.tuberculosis_H37Rv ---------------------------------------------
MMAR_1093|M.marinum_M ---------------------------------------------
MUL_0851|M.ulcerans_Agy99 ---------------------------------------------
MSMEG_3587|M.smegmatis_MC2_155 ---------------------------------------------
MAB_3866c|M.abscessus_ATCC_199 ---------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK IVIATLPPEFSMWHRFDVVDRARAQFTVPVTHVVATSAVGNQVPR
MAV_4626|M.avium_104 ---------------------------------------------
MLBr_01305|M.leprae_Br4923 ---------------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 ---------------------------------------------
TH_3126|M.thermoresistible__bu ---------------------------------------------