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VTTHSAVLPATSYVRRPGYLLAALLMFASLVAMSQPVPAAADPCAAVDVSFARGRDEPVGLGRVGDAFVG ALQNRVSNMNVYPVNYSAGLLSTGEGADDLRNHLSEVASSCPNTKFVIGGYSMGATVVDDVAGNPPPDVA SRIRGIATFGNIDRRGGGMTGPLAGRWIDQCNPGDPVCQEGGRSWTAHTSYEQTNLPAQAASFVAGKL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3765 | - | - | 100% (208) | cutinase cut3 precursor |
| M. abscessus ATCC 19977 | MAB_3766 | - | 7e-57 | 54.39% (228) | cutinase cut3 precursor |
| M. abscessus ATCC 19977 | MAB_3763 | - | 3e-41 | 44.34% (212) | cutinase cut2 precursor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3481 | cut3 | 6e-38 | 43.06% (209) | cutinase precursor CUT3 |
| M. gilvum PYR-GCK | Mflv_4966 | - | 1e-33 | 40.59% (202) | cutinase |
| M. tuberculosis H37Rv | Rv3451 | cut3 | 6e-38 | 43.06% (209) | cutinase precursor CUT3 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1098 | cut3 | 3e-39 | 42.48% (226) | cutinase precursor, Cut3 |
| M. avium 104 | MAV_4394 | - | 1e-40 | 44.44% (207) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_2095 | - | 1e-33 | 41.31% (213) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_4127 | - | 3e-29 | 40.20% (199) | PUTATIVE serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_0856 | cut3 | 3e-38 | 42.04% (226) | cutinase precursor, Cut3 |
| M. vanbaalenii PYR-1 | Mvan_1440 | - | 3e-34 | 39.17% (217) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4394|M.avium_104 MKTHRIGRL----LGLGSSALITAAGLLGAP----AAVPVASADDCPDVE
MSMEG_2095|M.smegmatis_MC2_155 MLSRRIG----------AWALMAAGIALVVP----ARLPVASAAECPDAE
Mb3481|M.bovis_AF2122/97 MNNRPIRLLTSGRAGLGAGALITAVVLLIALGAVWT--PVAFADGCPDAE
Rv3451|M.tuberculosis_H37Rv MNNRPIRLLTSGRAGLGAGALITAVVLLIALGAVWT--PVAFADGCPDAE
MMAR_1098|M.marinum_M MNKHPLAVL--------AGALVTATGLLAAPSITGTAIPSASAADCPDAE
MUL_0856|M.ulcerans_Agy99 MNKHPLAVL--------AGALVTATGLLAAPSITGTAIPSASAADCPDAE
MAB_3765|M.abscessus_ATCC_1997 MTTHSAVLP--ATSYVRRPGYLLAALLMFASLVAMSQPVPAAADPCAAVD
Mflv_4966|M.gilvum_PYR-GCK --------------------MVPMAALAVMP------TTTASAQPCPDVE
Mvan_1440|M.vanbaalenii_PYR-1 MLSDRLIRR---ILSAAAAVTASVAAVAVLP------AAPASAQPCPDVE
TH_4127|M.thermoresistible__bu -------------------VLGSAALLAGVP------APTAAAIPCSDVE
* * *. .:
MAV_4394|M.avium_104 VIFARGTNEPPGMGRVGDAFVESLRQQTSGLNIDTYGVNYAASKLQLHGG
MSMEG_2095|M.smegmatis_MC2_155 VVFARGTDEPAGLGRVGTAFVDALRKQAAGLEIDAYAVDYKAGKLQLSGG
Mb3481|M.bovis_AF2122/97 VTFARGTGEPPGIGRVGQAFVDSLRQQT-GMEIGVYPVNYAASRLQLHGG
Rv3451|M.tuberculosis_H37Rv VTFARGTGEPPGIGRVGQAFVDSLRQQT-GMEIGVYPVNYAASRLQLHGG
MMAR_1098|M.marinum_M VVFARGTSEPPGIGRVGEAFVDSLRQQT-GKNIGVYAVNYPASRLQLHGG
MUL_0856|M.ulcerans_Agy99 VVFPRGTSEPPGIGRVGEAFVDSLRQQT-GKNIGVYAVNYPASRLQLHGG
MAB_3765|M.abscessus_ATCC_1997 VSFARGRDEPVGLGRVGDAFVGALQNRV--SNMNVYPVNYSAG--LLSTG
Mflv_4966|M.gilvum_PYR-GCK VVFARGTSEPPGVGRVGQALADQLRNQLGGRTVGTYGVVYPASYDFFTSG
Mvan_1440|M.vanbaalenii_PYR-1 VVFARGTSEPPGVGRVGQALADTLRNQLGGRTVGTYGVNYPASYDFLNTA
TH_4127|M.thermoresistible__bu VVFARGTSEPPGVGRVGQALANALQARLPGRTVSTYGVSYPATYDFLAAT
* *.** .** *:**** *:. *: : :..* * * * :
MAV_4394|M.avium_104 DGANDTINRIKQAVQKCPNTKIVLGGYSQGASVMDIVAGVPIGG-----I
MSMEG_2095|M.smegmatis_MC2_155 DGAKDAIAHIKSTVSSCSNTKIVLGGYSQGASVVNIAAGNQLGG-----I
Mb3481|M.bovis_AF2122/97 DGANDAISHIKSMASSCPNTKLVLGGYSQGATVIDIVAGVPLGS-----I
Rv3451|M.tuberculosis_H37Rv DGANDAISHIKSMASSCPNTKLVLGGYSQGATVIDIVAGVPLGS-----I
MMAR_1098|M.marinum_M DGANDVISHVKSMASSCPNTKIVLGGYSQGADVIDIVAGVPLAG-----I
MUL_0856|M.ulcerans_Agy99 DGANDVISHVKSMASSCPNTKIVQGGYSQGADVIDIVAGVPLAG-----I
MAB_3765|M.abscessus_ATCC_1997 EGADDLRNHLSEVASSCPNTKFVIGGYSMGATVVDDVAGNP---------
Mflv_4966|M.gilvum_PYR-GCK DGAADATNRISVMAAQCPNTRIVLGGYSQGAAVVDMLAGVPPLGNRIGDV
Mvan_1440|M.vanbaalenii_PYR-1 TGATDATGRIAYMAAQCPNTRIVLGGYSQGAAVVAMLAGVPPLGDRIGSI
TH_4127|M.thermoresistible__bu DGANDATARITTLAQQCPSTRVVLGGYSQGAAVVDMLGGLPPLGDRVGLV
** * :: . .*..*:.* **** ** *: .*
MAV_4394|M.avium_104 NWGSSITPDLASHVAAVATFGDVADRAGGTLPSQSALLGSKAIDLCNPND
MSMEG_2095|M.smegmatis_MC2_155 TWADPLPAQYANNVAAIVTFGDIATRTGEALSTRSNLFGSKAIDLCNPSD
Mb3481|M.bovis_AF2122/97 SFGSPLPAAYADNVAAVAVFGNPSNRAGGSLSSLSPLFGSKAIDLCNPTD
Rv3451|M.tuberculosis_H37Rv SFGSPLPAAYADNVAAVAVFGNPSNRAGGSLSSLSPLFGSKAIDLCNPTD
MMAR_1098|M.marinum_M SFGNELPAQYADNIAAVAVFGNVANRSGGSLTTQSSLLGSKSIDLCNPSD
MUL_0856|M.ulcerans_Agy99 SFGNELPAQYADNIAAVAVFGNVANRSGGSLTTQSSLLGSKSIDLCNPSD
MAB_3765|M.abscessus_ATCC_1997 ------PPDVASRIRGIATFGNIDRRGGG----MTGPLAGRWIDQCNPGD
Mflv_4966|M.gilvum_PYR-GCK GLARPLPGGLNGNVAAVAVFGNPATKFGNPVS-ARGSFAGKALDLCADGD
Mvan_1440|M.vanbaalenii_PYR-1 GSAPPLPGGLTGNVAAVAVFGNPSAKFGSPVS-ARGTFAGKAIDLCADGD
TH_4127|M.thermoresistible__bu GSA--LPTGSVGNVAAVAVFGNPSAKFGRPIN-TSPVFGGRGIDLCSDGD
. ..: .:..**: : * :..: :* * *
MAV_4394|M.avium_104 PICHAGPGNEWSGHTEGYVPVYTTQAAAFVASKL-MGAGQSVPGYGPSVP
MSMEG_2095|M.smegmatis_MC2_155 PICHAGQGNEWSGHTDGYVPVYTTQAAVFAAAKLRAGSGRSVPGYG-TVP
Mb3481|M.bovis_AF2122/97 PICHVGPGNEFSGHIDGYIPTYTTQAASFVVQRLRAGSVP----------
Rv3451|M.tuberculosis_H37Rv PICHVGPGNEFSGHIDGYIPTYTTQAASFVVQRLRAGSVP----------
MMAR_1098|M.marinum_M PICHSGPGNDWNGHTDGYVPTYTTQAASFVAAKLAASSMAPV--------
MUL_0856|M.ulcerans_Agy99 PICHSGPGNDWNGHTDGYVPTYTTQAASFVAAKLAASSMAPV--------
MAB_3765|M.abscessus_ATCC_1997 PVCQEG-GRSWTAHTSYEQTNLPAQAASFVAGKL----------------
Mflv_4966|M.gilvum_PYR-GCK PICSDG--RNPFAHTSYERSPLIGQAAGFAAGRL----------------
Mvan_1440|M.vanbaalenii_PYR-1 PICSDG--RNPFAHTSYERSPFIGQAAGFAAGRV----------------
TH_4127|M.thermoresistible__bu PICSNG--RNPFAHTNYETSVHIETAADFAAGLI----------------
*:* * .. .* . . ** *.. :
MAV_4394|M.avium_104 GAGP-QSPGYGQQS-----PVYGQTPPGSGPSIHDNAPGPGTAPAPA--V
MSMEG_2095|M.smegmatis_MC2_155 EYGPGYGPGYGSGNGQGYGPLYGPATPGYDPESPTHGPPPGYVPAPPGYV
Mb3481|M.bovis_AF2122/97 ------------------------HLPGSVP------QLPGSVLQMPG--
Rv3451|M.tuberculosis_H37Rv ------------------------HLPGSVP------QLPGSVLQMPG--
MMAR_1098|M.marinum_M -----------------------VQLPGPVP------RAPGPAPQAPGPA
MUL_0856|M.ulcerans_Agy99 -----------------------VRLPGPVP------RAPGPAPQAPGPA
MAB_3765|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4966|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1440|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4127|M.thermoresistible__bu --------------------------------------------------
MAV_4394|M.avium_104 PSTP------PSQAP------LV----
MSMEG_2095|M.smegmatis_MC2_155 PETPGYELPGPSAAEPSAEVGLVSAVG
Mb3481|M.bovis_AF2122/97 TAAP-----APESLHGR----------
Rv3451|M.tuberculosis_H37Rv TAAP-----APESLHGR----------
MMAR_1098|M.marinum_M TASPGTPVGATGTLVGAH---------
MUL_0856|M.ulcerans_Agy99 TASPGTPVGATGTLVGAH---------
MAB_3765|M.abscessus_ATCC_1997 ---------------------------
Mflv_4966|M.gilvum_PYR-GCK ---------------------------
Mvan_1440|M.vanbaalenii_PYR-1 ---------------------------
TH_4127|M.thermoresistible__bu ---------------------------