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MVPMAALAVMPTTTASAQPCPDVEVVFARGTSEPPGVGRVGQALADQLRNQLGGRTVGTYGVVYPASYDF FTSGDGAADATNRISVMAAQCPNTRIVLGGYSQGAAVVDMLAGVPPLGNRIGDVGLARPLPGGLNGNVAA VAVFGNPATKFGNPVSARGSFAGKALDLCADGDPICSDGRNPFAHTSYERSPLIGQAAGFAAGRL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4966 | - | - | 100% (205) | cutinase |
| M. gilvum PYR-GCK | Mflv_4965 | - | 1e-52 | 49.26% (203) | cutinase |
| M. gilvum PYR-GCK | Mflv_4432 | - | 7e-46 | 49.21% (189) | cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3482 | cut4 | 7e-47 | 48.78% (205) | cutinase precursor CUT4 |
| M. tuberculosis H37Rv | Rv3452 | cut4 | 7e-47 | 48.78% (205) | cutinase precursor CUT4 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3766 | - | 7e-43 | 45.58% (215) | cutinase cut3 precursor |
| M. marinum M | MMAR_1097 | cut4 | 4e-47 | 48.51% (202) | cutinase precursor, Cut4 |
| M. avium 104 | MAV_4283 | - | 1e-57 | 58.15% (184) | cutinase Cut3 |
| M. smegmatis MC2 155 | MSMEG_1529 | - | 7e-81 | 70.85% (199) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_4127 | - | 1e-74 | 68.84% (199) | PUTATIVE serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_0855 | cut4 | 9e-47 | 48.02% (202) | cutinase precursor, Cut4 |
| M. vanbaalenii PYR-1 | Mvan_1440 | - | 3e-98 | 84.65% (202) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3482|M.bovis_AF2122/97 -----MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTPALAP-PAS
Rv3452|M.tuberculosis_H37Rv -----MIPRPQPHSGRWRAGAARRLTSLVAAAFAAATLLLTPALAP-PAS
MMAR_1097|M.marinum_M MWLFPLDAQKWARSGRGRTRLARRCAGLVATTIAACAVLLAFPLVP-KAA
MUL_0855|M.ulcerans_Agy99 MWLFPLDAQKWARSGRGRTRLARRCAGLVATTIAACAVLLAFPLVP-KAA
Mflv_4966|M.gilvum_PYR-GCK --------------------------------MVPMAALAVMPTTT-ASA
Mvan_1440|M.vanbaalenii_PYR-1 ---------------MLSDRLIRRILSAAAAVTASVAAVAVLPAAP-ASA
MSMEG_1529|M.smegmatis_MC2_155 ------------------------MAAFASAVLCAGAALATGPAPV-ASA
TH_4127|M.thermoresistible__bu -------------------------------VLGSAALLAGVPAPT-AAA
MAV_4283|M.avium_104 --------------------------------------------------
MAB_3766|M.abscessus_ATCC_1997 --------MTTHQRGTRVGVVLSSFVVLTVLVLSAASVVGPVSAVPRASA
Mb3482|M.bovis_AF2122/97 AGCPDAEVVFARGTGEPPGLGRVGQAFVSSLR---QQTNKSIGTYGVNYP
Rv3452|M.tuberculosis_H37Rv AGCPDAEVVFARGTGEPPGLGRVGQAFVSSLR---QQTNKSIGTYGVNYP
MMAR_1097|M.marinum_M AACPDVQVVFARGTGEPPGLGRVGNAMVASLR---QKTDQSIGAYAVNYP
MUL_0855|M.ulcerans_Agy99 AACPDVQVVFARGTGEPPGLGRVGNAMVASLR---QKTDQSIGAYAVNYP
Mflv_4966|M.gilvum_PYR-GCK QPCPDVEVVFARGTSEPPGVGRVGQALADQLRN--QLGGRTVGTYGVVYP
Mvan_1440|M.vanbaalenii_PYR-1 QPCPDVEVVFARGTSEPPGVGRVGQALADTLRN--QLGGRTVGTYGVNYP
MSMEG_1529|M.smegmatis_MC2_155 EPCSDIEVVFARGTSEPAGIGRVGQALTDAIRN--QVGGRTVSTYGVNYP
TH_4127|M.thermoresistible__bu IPCSDVEVVFARGTSEPPGVGRVGQALANALQA--RLPGRTVSTYGVSYP
MAV_4283|M.avium_104 -----MQLIFARGTAEPPGLGAVGDALFAALQP--ALGNRNVDAYAVNYP
MAB_3766|M.abscessus_ATCC_1997 DPCSDVDVSFARGRKEPVGLGRVGDEFVDSLTPRVQATGATMNVYPVNYD
:: **** ** *:* **: : : . .:..* * *
Mb3482|M.bovis_AF2122/97 ANGDFLAAADGANDASDHIQQMASACRATRLVLGGYSQGAAVIDIVTAAP
Rv3452|M.tuberculosis_H37Rv ANGDFLAAADGANDASDHIQQMASACRATRLVLGGYSQGAAVIDIVTAAP
MMAR_1097|M.marinum_M ANKDFLAAADGANDASDHVQQMTNECPNTKLVLGGYSQGAAVIDIVTAAP
MUL_0855|M.ulcerans_Agy99 ANKDFLAAADGANDASDHVQQMTNECPNTKLVLGGYSQGAAVINIVTAAP
Mflv_4966|M.gilvum_PYR-GCK ASYDFFTSGDGAADATNRISVMAAQCPNTRIVLGGYSQGAAVVDMLAGVP
Mvan_1440|M.vanbaalenii_PYR-1 ASYDFLNTATGATDATGRIAYMAAQCPNTRIVLGGYSQGAAVVAMLAGVP
MSMEG_1529|M.smegmatis_MC2_155 ATYDFLAAADGANDATNRIATLAEQCPSTRVVLGGYSQGAAVVDMLLGIP
TH_4127|M.thermoresistible__bu ATYDFLAATDGANDATARITTLAQQCPSTRVVLGGYSQGAAVVDMLGGLP
MAV_4283|M.avium_104 ASYNFLTTADGANDARDHIAEMVDRCPSTRLVLGGFSQGAAAVSMLAGVP
MAB_3766|M.abscessus_ATCC_1997 AG--IFSAGGGANDLSNHLQSVAASCPRTKLVIGGYSMGAEVIDTIIGVP
* :: : ** * :: :. * *::*:**:* ** .: : . *
Mb3482|M.bovis_AF2122/97 LPG-----LGFTQPLPPAADDHIAAIALFGNPSGRAGGLMSALTPQFGSK
Rv3452|M.tuberculosis_H37Rv LPG-----LGFTQPLPPAADDHIAAIALFGNPSGRAGGLMSALTPQFGSK
MMAR_1097|M.marinum_M LPG-----LGFTQPLPAQAAQHVAAVTLFGNPSGRAGGLMTALSPHFGGK
MUL_0855|M.ulcerans_Agy99 LPG-----LGFTQPLPAQAAQHVAAVTLFGNPSGRAGGLMTALSPHFGGK
Mflv_4966|M.gilvum_PYR-GCK PLGNRIGDVGLARPLPGGLNGNVAAVAVFGNPATKFGNPVSARG-SFAGK
Mvan_1440|M.vanbaalenii_PYR-1 PLGDRIGSIGSAPPLPGGLTGNVAAVAVFGNPSAKFGSPVSARG-TFAGK
MSMEG_1529|M.smegmatis_MC2_155 PLGNKVGNFGSAPPLPSNLMNNVAAVAVFGNPSAKFGIPVTSR---FGGR
TH_4127|M.thermoresistible__bu PLGDRVGLVGSA--LPTGSVGNVAAVAVFGNPSAKFGRPINTSP-VFGGR
MAV_4283|M.avium_104 PVGQRIGNFGSAPPLDPGLASKIAAVAVFGNPGNRFNTPLSTTG-AFAGR
MAB_3766|M.abscessus_ATCC_1997 NVG-----IGFNRPLPPTVGDRIVAIATFGNATHRTGGPLSGIAGVFGSR
* .* * .:.*:: ***. : . :. *..:
Mb3482|M.bovis_AF2122/97 TINLCNNGDPICSDG--NRWRAHLGYVPG-MTNQAARFVASRI-------
Rv3452|M.tuberculosis_H37Rv TINLCNNGDPICSDG--NRWRAHLGYVPG-MTNQAARFVASRI-------
MMAR_1097|M.marinum_M ILNLCNTGDPICSDG--DQWKAHTGYVPG-LTNKAASFVAGRI-------
MUL_0855|M.ulcerans_Agy99 ILNLCNTGDPICSDG--DQWKAHTGYVPG-LTNKAASFVAGRI-------
Mflv_4966|M.gilvum_PYR-GCK ALDLCADGDPICSDG--RNPFAHTSYERSPLIGQAAGFAAGRL-------
Mvan_1440|M.vanbaalenii_PYR-1 AIDLCADGDPICSDG--RNPFAHTSYERSPFIGQAAGFAAGRV-------
MSMEG_1529|M.smegmatis_MC2_155 AIDACSDGDPICSDG--RNPFAHTHYESSPFIPQAAGLIAGLV-------
TH_4127|M.thermoresistible__bu GIDLCSDGDPICSNG--RNPFAHTNYETSVHIETAADFAAGLI-------
MAV_4283|M.avium_104 AIDLCSDGDPVCVVGG-RDRDAHHVYEDPPYPAQAAGFIAGRV-------
MAB_3766|M.abscessus_ATCC_1997 AIDLCNQGDPICMAGPNNSWDAHTSYERTGLPAEAAAFVASKLNRHGESE
:: * ***:* * ** * ** : *. :
Mb3482|M.bovis_AF2122/97 --
Rv3452|M.tuberculosis_H37Rv --
MMAR_1097|M.marinum_M --
MUL_0855|M.ulcerans_Agy99 --
Mflv_4966|M.gilvum_PYR-GCK --
Mvan_1440|M.vanbaalenii_PYR-1 --
MSMEG_1529|M.smegmatis_MC2_155 --
TH_4127|M.thermoresistible__bu --
MAV_4283|M.avium_104 --
MAB_3766|M.abscessus_ATCC_1997 AE