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M. abscessus ATCC 19977 MAB_3489c (-)

annotation: acyl-CoA synthetase
coordinates: 3531101 - 3533083
length: 660

FFTGVGSCETLIESTEAGPDPEYVVLSAKVKARVRLILSNTKESLAIEGVDNDGLISVRLFEERSAQTRV
RITVLRAASVLPAGIKKPSAAVNQWLMDGLDRIDDYLSGAPTSTVSNSGDNGNLQVSIAKLMVSVGVVRI
PRPDRGLRQLSSLARWGFTLQGGYAAAAARAPKQLAIADDAGQLTFEQLDRRAEGLATGLMRAGITETSK
IGLLARNNIAMVECLIAFGMLGVDVMLLNNALAATQIQIAVARNGLTKVFVDDDLDELVRYVPWEVELVS
TGRRSAINGRRGLDDFVVADKPGVLPPTRPGHQVVQTSGTSGTPKGALRPTPRGFAVIAAMLSRMPMKMN
ETMLISAPIFHAWGLGCLQISTPLRATVILQEKFDPEECLRAIATRKVTTMIAVPVMLQRIVDLPAKVRQ
KYDTSSLRLVACSGSPLNASLVQRFTEAFGEVLYNFYGSTEVSWATIADPEDLAIAPTTVGRPPLGTTIA
ILDADRRPVPRGVTGRIFVGNEMLFEGYVADPSPASVNGLLDTGDLGHLDADGRLYIDGRDDEMIISGGE
NVFPRPVEDALAFLPQVSDVAVVGTSDDSFGQRLSAFVVLNKDAGLDGDMVRAFIKNRLSKFHVPRDVYF
VEALPRTSTGKVIKRLLLADCERDGVRPQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3489c--100% (660)acyl-CoA synthetase
M. abscessus ATCC 19977MAB_4340c-4e-9436.53% (542) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_2539c-1e-8736.45% (513) fatty-acid-CoA ligase FadD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1462cfadD123e-9837.50% (520) acyl-CoA synthetase
M. gilvum PYR-GCKMflv_2427-2e-9738.42% (518) acyl-CoA synthetase
M. tuberculosis H37RvRv1427cfadD123e-9837.50% (520) acyl-CoA synthetase
M. leprae Br4923MLBr_02546fadD22e-9838.69% (535) acyl-CoA synthetase
M. marinum MMMAR_2233fadD121e-10138.30% (530) long-chain-fatty-acid--CoA ligase FadD12
M. avium 104MAV_5220-1e-9538.58% (521) acyl-CoA synthetase
M. smegmatis MC2 155MSMEG_0304-6e-9937.83% (526) acyl-CoA synthetase
M. thermoresistible (build 8)TH_4130-1e-10037.41% (548) PUTATIVE putative cytochrome P450 superfamily protein
M. ulcerans Agy99MUL_4827fadD12_21e-10038.52% (527) acyl-CoA synthetase
M. vanbaalenii PYR-1Mvan_4225-1e-9739.06% (512) acyl-CoA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1462c|M.bovis_AF2122/97           --------------------------------------------------
Rv1427c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2233|M.marinum_M               --------------------------------------------------
MSMEG_0304|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2427|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4225|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4130|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
MAV_5220|M.avium_104                --------------------------------------------------
MUL_4827|M.ulcerans_Agy99           --------------------------------------------------
MAB_3489c|M.abscessus_ATCC_199      MFFTGVGSCETLIESTEAGPDPEYVVLSAKVKARVRLILSNTKESLAIEG
                                                                                      

Mb1462c|M.bovis_AF2122/97           --------------------------------------------------
Rv1427c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2233|M.marinum_M               --------------------------------------------------
MSMEG_0304|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2427|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4225|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4130|M.thermoresistible__bu      --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
MAV_5220|M.avium_104                --------------------------------------------------
MUL_4827|M.ulcerans_Agy99           --------------------------------------------------
MAB_3489c|M.abscessus_ATCC_199      VDNDGLISVRLFEERSAQTRVRITVLRAASVLPAGIKKPSAAVNQWLMDG
                                                                                      

Mb1462c|M.bovis_AF2122/97           ----------------MRIR----QAFGLIATMRRAGLIAPLRPDRYLRI
Rv1427c|M.tuberculosis_H37Rv        ----------------MRIR----QAFGLIATMRRAGLIAPLRPDRYLRI
MMAR_2233|M.marinum_M               --------------MAPRID----QILGLITTLARSGLIAPMRPDRYLKI
MSMEG_0304|M.smegmatis_MC2_155      ------------MGLLDRITDPLIDTVGMVTTMRRAGLIAPLRPDKYLRI
Mflv_2427|M.gilvum_PYR-GCK          ---------------MSSAA----DQFGLLATLWRARLIAPMRPDRYLRM
Mvan_4225|M.vanbaalenii_PYR-1       ------------------MA----DPLGLLATLWRARLIAPMRPDRYLRM
TH_4130|M.thermoresistible__bu      ------------------MA----KTIDTLRTLTRAGLIAPLRPDKYLRM
MLBr_02546|M.leprae_Br4923          ------------MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAM
MAV_5220|M.avium_104                ------------------MAP------TAARALVRSGLLNPPSPRAVLRL
MUL_4827|M.ulcerans_Agy99           -----------------MMAAG--VVTTAARALLGSGLLSPSSPAAALRL
MAB_3489c|M.abscessus_ATCC_199      LDRIDDYLSGAPTSTVSNSGDNGNLQVSIAKLMVSVGVVRIPRPDRGLRQ
                                                                    :     :    *      

Mb1462c|M.bovis_AF2122/97           VAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERGNALAAA
Rv1427c|M.tuberculosis_H37Rv        VAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERGNALAAA
MMAR_2233|M.marinum_M               AAAMRREGMGFTAGFAAAAQRCPDRPGLVDELGTLTWRQLDERSNALAAA
MSMEG_0304|M.smegmatis_MC2_155      VAAMARENMSVTSGFASAAQRCPDRPGLVDELGTLTWREIDQQADALAAG
Mflv_2427|M.gilvum_PYR-GCK          GLAMRRAGLTATVGFAAAAQRCPDRPGIIDELGTLTWKQLDDRCDALGVA
Mvan_4225|M.vanbaalenii_PYR-1       GLAMRRAGLTATVGFAAAAQRCPDLPGIIDELGTLTWKQLDDRCDALAAA
TH_4130|M.thermoresistible__bu      TAAVRRTGVSVTVGFAVAAQRCGDRIGLVDEIGELTWRELDDECNALAAA
MLBr_02546|M.leprae_Br4923          AVAMRKWG-DLAMLPAMPARRSPHRAALIDEEGTLTYKELDRAAHALANG
MAV_5220|M.avium_104                LREASRGGTNPYTLLAVTAARWPGRTAIIDDDGALSYRELQRATESLARR
MUL_4827|M.ulcerans_Agy99           VRELYRGGTNLYTPLAIAAARWPERTAIVDDDGALSYREIQTMTESVAGE
MAB_3489c|M.abscessus_ATCC_199      LSSLARWGFTLQGGYAAAAARAPKQLAIADDAGQLTFEQLDRRAEGLATG
                                         : .       * .* *     .: *: * *::.:::   ..:.  

Mb1462c|M.bovis_AF2122/97           LQALPAGPPR-------VVGIMCRNHRGFVDALLAVNRIGAHILLLNTSF
Rv1427c|M.tuberculosis_H37Rv        LQALPAGPPR-------VVGIMCRNHRGFVDALLAVNRIGAHILLLNTSF
MMAR_2233|M.marinum_M               LQALPAGSPK-------VVGIMCRNHRGFVEALVAANRIGADILLLNTAF
MSMEG_0304|M.smegmatis_MC2_155      LQALSGGAPR-------VLGIMARNHRGFVLSLIAANRIGADVLLLNTSF
Mflv_2427|M.gilvum_PYR-GCK          LQKE---KPK-------TVAVMCRNHRGFVEALVAANRIGADVLLLNTSF
Mvan_4225|M.vanbaalenii_PYR-1       LQKH---TPR-------TVAVMCRNHRGFVEALVGANRIGADVLLLNTSF
TH_4130|M.thermoresistible__bu      LQDRAAGQGKDGGKGRGAIGIMCRNHRGFIEALVAADRIGATVLLLNTSF
MLBr_02546|M.leprae_Br4923          LIAKGVRGGD-------GIAILARNHRWFVIANYGCARVGARIILLNSEF
MAV_5220|M.avium_104                LTRDGVAPGR-------AVGVMCRNGRGFVTAVFAVTLLGADVVPISTEF
MUL_4827|M.ulcerans_Agy99           LTLAGIGPGQ-------AVGVMCRNGRNFVAAAFAAGLVGADVVLVNTEF
MAB_3489c|M.abscessus_ATCC_199      LMRAGITETS-------KIGLLARNNIAMVECLIAFGMLGVDVMLLNNAL
                                    *                 :.::.**   :: .  .   :*. :: :.. :

Mb1462c|M.bovis_AF2122/97           AGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQA-TRIVAWTD----
Rv1427c|M.tuberculosis_H37Rv        AGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQA-TRIVAWTD----
MMAR_2233|M.marinum_M               AGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQA-TRIVAWSD----
MSMEG_0304|M.smegmatis_MC2_155      SGPALAEVVSREKVDAVIYDEEFTDTVDRALAGAPEAPTRIVAWTDT---
Mflv_2427|M.gilvum_PYR-GCK          AGPAMAEVVEREGADIVIYDQEFTETVDRALADTCGA-RRIVAWVDDPA-
Mvan_4225|M.vanbaalenii_PYR-1       AGPAMAEVIEREGADIVIYDQEFTATVDRALRDVPGT-TRILAWTD--A-
TH_4130|M.thermoresistible__bu      AGPALAEVVDREGVDTIVYDEEFTDIVDRALADRPTA-TRILAWVDEPAS
MLBr_02546|M.leprae_Br4923          SGPQIKEVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEP-
MAV_5220|M.avium_104                RSDALAAALRAHHISTVVADNEFAERIAAADDAVAVI-------------
MUL_4827|M.ulcerans_Agy99           RATALAAALEAHQMRVMLCDDEFVDQVAGTGESVLVI-------------
MAB_3489c|M.abscessus_ATCC_199      AATQIQIAVARNGLTKVFVDDDLDELVRYVPWEVELVSTGRRSAIN----
                                     .  :  .   .    :. *::    :  .                    

Mb1462c|M.bovis_AF2122/97           --EDHDLTVEKLVAAHAGRRPEH---TGSHGKVILLTSGTTGTPKGARHS
Rv1427c|M.tuberculosis_H37Rv        --EDHDLTVEKLVAAHAGRRPEH---TGSHGKVILLTSGTTGTPKGARHS
MMAR_2233|M.marinum_M               --GQHDLTVEQLVNAHLGDQPER---TGRTGRLILLTSGTTGTPKGAKHS
MSMEG_0304|M.smegmatis_MC2_155      --AAHDVTVAALTEKFAGRQPQR---GGQKSKVILLTSGTTGTPKGAKHS
Mflv_2427|M.gilvum_PYR-GCK          --QAGTATVEALIDAHLGQRPQP---ATRKSDVILLTSGTTGSPKGAKRS
Mvan_4225|M.vanbaalenii_PYR-1       --DDGSTTLEALIDAHLGQRPEP---ATRKSDIILLTSGTTGTPKGAKRS
TH_4130|M.thermoresistible__bu      GPALPHPTVADLVAEHRGRRPAKPAAGDEGSRIILLTSGTTGTPKGARAA
MLBr_02546|M.leprae_Br4923          -PGSTDETLAELIARSSSAPAPK---VRKRASIIILTSGTTGTPKGANRN
MAV_5220|M.avium_104                --DPATAGAEESGGRPAVAAP---------GRIVLLTSGTTGKPKGVPRA
MUL_4827|M.ulcerans_Agy99           --DPSTVTARDCA-RPKVAPS---------GRIVLLTSGTTGVPKGVPRK
MAB_3489c|M.abscessus_ATCC_199      --GRRGLDDFVVADKPGVLPPTR------PGHQVVQTSGTSGTPKGALRP
                                                        .         .  :: ****:* ***.   

Mb1462c|M.bovis_AF2122/97           GG---GIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTI
Rv1427c|M.tuberculosis_H37Rv        GG---GIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTI
MMAR_2233|M.marinum_M               GGS-GGIGTLKAILDRTPWRAEQPIVIVAPMFHAWGFSQLVLAASLACTI
MSMEG_0304|M.smegmatis_MC2_155      GG---GPEILKAILDRTPWRAEEPVVIVAPMFHAWGFSQLAFAASMACTI
Mflv_2427|M.gilvum_PYR-GCK          AGS-GGSGDLKAVLDRTPWRAEEPIVIAAPMFHAWGFSQLLFAALLACPI
Mvan_4225|M.vanbaalenii_PYR-1       AGS-GGASDLKAVLDRTPWRAGEPIVIAAPMFHAWGFSQLLFAALLACPI
TH_4130|M.thermoresistible__bu      SS--GGAGELAAILGRVPWRAEQTTVIAAPMFHAWGYSQLLFSALLACTI
MLBr_02546|M.leprae_Br4923          TP--ASLAPLGGILSKVPFRAHEVTLLPAPMFHALGYLHATLAMFLGSTL
MAV_5220|M.avium_104                PQLRSAVGVWVTILDRTRLRTGSRISVAMPMFHGLGLGMLMLTIALGGTV
MUL_4827|M.ulcerans_Agy99           PKVSSGIGVSATLLERTRLRVGSRMTLATPMFHGLGFGMLVLTISLGGTV
MAB_3489c|M.abscessus_ATCC_199      TPR--GFAVIAAMLSRMPMKMNETMLISAPIFHAWGLGCLQISTPLRATV
                                         .      :* :   :  .   :  *:**. *     ::  :  .:

Mb1462c|M.bovis_AF2122/97           VTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLR
Rv1427c|M.tuberculosis_H37Rv        VTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLR
MMAR_2233|M.marinum_M               VTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLNRYSGRTLR
MSMEG_0304|M.smegmatis_MC2_155      ITRRKFDPEATLELVDRHRATGLCVVPVMFDRIMELPEDVLNRYDGRSLR
Mflv_2427|M.gilvum_PYR-GCK          VTRRKFDPAATLALVDKYRATGLAVVPVMFDRIMDLPDEVRNRYSGRSLR
Mvan_4225|M.vanbaalenii_PYR-1       VTRRKFDPEATLALIDRHRATGLAVVPVMFDRIMELPAEVRNRYSGRSLR
TH_4130|M.thermoresistible__bu      VTRRRFDPEATLQLVDRYRATGLVVVPVMLDRIMELPADVRDRYSGRSLR
MLBr_02546|M.leprae_Br4923          VLRRRFKPATVLEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLR
MAV_5220|M.avium_104                LTHRHFDAEAALAQASLHRADAFTAVPVVLARILELPPRVRARNPLPQLR
MUL_4827|M.ulcerans_Agy99           LTRRHFDAEATLAQTSLHRADGLSVVPIMLARILDLPDQVRARNPLPCLR
MAB_3489c|M.abscessus_ATCC_199      ILQEKFDPEECLRAIATRKVTTMIAVPVMLQRIVDLPAKVRQKYDTSSLR
                                    : :.:*..   *      :.  : .**::: **::    :  :     **

Mb1462c|M.bovis_AF2122/97           FAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD
Rv1427c|M.tuberculosis_H37Rv        FAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPD
MMAR_2233|M.marinum_M               FAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPD
MSMEG_0304|M.smegmatis_MC2_155      FAAASGSRMRPDVVIAFMDRFGDVIYNNYNATEAGMIATATPADLRAAPD
Mflv_2427|M.gilvum_PYR-GCK          FATASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPEDLRAAPD
Mvan_4225|M.vanbaalenii_PYR-1       FATASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPADLRAAPD
TH_4130|M.thermoresistible__bu      FVTASGSRMRPDVVLDFMDRFGDVIYNNYNATEAGMIATATPADLRAAPS
MLBr_02546|M.leprae_Br4923          VVFVSGSQLGAELATRALEELGPVIYNMYGSTEIAFATIAGPKDLQINSA
MAV_5220|M.avium_104                VVMSSGDRLDPTLGQRFMDTYGDILYNGYGSTEVGIGALATPADLRDAPE
MUL_4827|M.ulcerans_Agy99           AVISSGDRLDPSLARRFMEAYGDVLYNLYGSTEVGIGALATPAELRDWPE
MAB_3489c|M.abscessus_ATCC_199      LVACSGSPLNASLVQRFTEAFGEVLYNFYGSTEVSWATIADPEDLAIAPT
                                     .  **. : . :     :  * ::** *.:** .  : * * :*   . 

Mb1462c|M.bovis_AF2122/97           TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHA
Rv1427c|M.tuberculosis_H37Rv        TAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHA
MMAR_2233|M.marinum_M               TAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHA
MSMEG_0304|M.smegmatis_MC2_155      TAGRPAEGTEIRILDGDLRDLPTGEVGTIYVRNSTQFDGYTSGTTKDFHE
Mflv_2427|M.gilvum_PYR-GCK          TAGKAADGTELRILDAEHRELPTGEVGQIFVRSGTLFDGYTSGSTKDFHD
Mvan_4225|M.vanbaalenii_PYR-1       TAGRAADGTELRILDAEHRDVPTGEVGQIFVRSSTLFDGYTSGTTKAFHD
TH_4130|M.thermoresistible__bu      TAGKPADGTEIRILDDALRPVPTGEVGQIFVRSNTLFDGYTSGTTKDFHE
MLBr_02546|M.leprae_Br4923          TVGPVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGGGGKQIID
MAV_5220|M.avium_104                TVGKPVAGCPVRILDRNNRPVGPRVTGRIFVGGELAGTRYTDGGGKAVVD
MUL_4827|M.ulcerans_Agy99           TVGRPVAGCPVRIFDRNGRPVGARVTGRIFVGGELNSDGYSGGGGKAVID
MAB_3489c|M.abscessus_ATCC_199      TVGRPPLGTTIAILDADRRPVPRGVTGRIFVGNEMLFEGYVADPSPASVN
                                    *.*    *  : *:*     :    .* *:* .      *  .       

Mb1462c|M.bovis_AF2122/97           GFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVA
Rv1427c|M.tuberculosis_H37Rv        GFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVA
MMAR_2233|M.marinum_M               GFMSSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVA
MSMEG_0304|M.smegmatis_MC2_155      GFMCSGDVGRLDDAGRLFVVGRDDEMIVSGGENVYPIEVEKVLTTHPAVA
Mflv_2427|M.gilvum_PYR-GCK          GFMASGDLGYLDDAGRLFVVGRDDEMIVSGGENVYPIEVEKTLMSHPEVA
Mvan_4225|M.vanbaalenii_PYR-1       GFMASGDMGYLDGAGRLFVVGRDDEMIVSGGENVYPIEVEKTLTTHAAVA
TH_4130|M.thermoresistible__bu      GFMASGDLGRLDEDGRLFVVGRDDEMIVSGGENVYPIEVEQVLARHPDVA
MLBr_02546|M.leprae_Br4923          GLLSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVV
MAV_5220|M.avium_104                GMTSTGDMGYLDNAGRLFIVGREDDMIISGGENVYPRAVENALAAHPAVA
MUL_4827|M.ulcerans_Agy99           GMASTGDMGYLDESGRLYIVGREDDMIVSGGENVYPRSLENALASHPDVA
MAB_3489c|M.abscessus_ATCC_199      GLLDTGDLGHLDADGRLYIDGRDDEMIISGGENVFPRPVEDALAFLPQVS
                                    *:  :**:* :*  . *:: **:*:**:*****::*  :*. :   . * 

Mb1462c|M.bovis_AF2122/97           EAAVIGVDDQQYGQRLAAFVVLKP----GVSATPETLKQHVRDNLANYKV
Rv1427c|M.tuberculosis_H37Rv        EAAVIGVDDQQYGQRLAAFVVLKP----GVSATPETLKQHVRDNLANYKV
MMAR_2233|M.marinum_M               EAAVIGVDDEQYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKV
MSMEG_0304|M.smegmatis_MC2_155      EAAVIGVDDEQFGQRLAAFVVLSG------DATVDDLKSHVRDNLANYKV
Mflv_2427|M.gilvum_PYR-GCK          EATVLGVEDSEYGQRLAAFVVLTD----GSGLTPEDLKQHVRANLANYKV
Mvan_4225|M.vanbaalenii_PYR-1       EAAVLGVDDEQYGQRLAAFVVPAA----GASVTVEELKQHVRENLANYKV
TH_4130|M.thermoresistible__bu      EATVIGVDDEQFGQRLAAFVVLRD----GAGATPDGLKQHVRDNLANYKV
MLBr_02546|M.leprae_Br4923          EATAIGVDDKEWGARLRAFVVKKQ----DATIDEDAIKAYVRDHLARYKV
MAV_5220|M.avium_104                DNAVIGVPDERFGHRLAAFVVLHP----GSGVDAAQLRDYLKDRVSRFEQ
MUL_4827|M.ulcerans_Agy99           ENAVIGVADEQFGQRLAAFVVARP----GCDIDADAIRDYLKGRVSRFEQ
MAB_3489c|M.abscessus_ATCC_199      DVAVVGTSDDSFGQRLSAFVVLNK----DAGLDGDMVRAFIKNRLSKFHV
                                    : :.:*. *. :* ** ****               :: .:: .::.:. 

Mb1462c|M.bovis_AF2122/97           PRDIAVLDELPRGITGKILRTELQSRVGS------
Rv1427c|M.tuberculosis_H37Rv        PRDIAVLDELPRGITGKILRTELQSRVGS------
MMAR_2233|M.marinum_M               PREIAVLDELPRGSTGKILRAELQAKVCGT-----
MSMEG_0304|M.smegmatis_MC2_155      PRDITILDELPRNSTGKIARRELQEKVNG------
Mflv_2427|M.gilvum_PYR-GCK          PRDITILPELPRGSTGKILRNELRGS---------
Mvan_4225|M.vanbaalenii_PYR-1       PRDITIMAELPRGSTGKILRNELRGR---------
TH_4130|M.thermoresistible__bu      PRSISVLDELPRGSTGKILRTELQARAQSG-----
MLBr_02546|M.leprae_Br4923          PREVIFLEELPRNPTGKVLKRELRDFEVH------
MAV_5220|M.avium_104                PRDINIVASIPRNPTGKVLRKELPG----------
MUL_4827|M.ulcerans_Agy99           PRDIYLVSSIPRNPAGKVLRKQLASYAEPEAQS--
MAB_3489c|M.abscessus_ATCC_199      PRDVYFVEALPRTSTGKVIKRLLLADCERDGVRPQ
                                    **.: .:  :**  :**: :  *