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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4130 | - | - | 100% (552) | putative cytochrome P450 superfamily protein |
| M. thermoresistible (build 8) | TH_4533 | - | e-114 | 41.41% (553) | PUTATIVE acyl-CoA synthase |
| M. thermoresistible (build 8) | TH_2878 | - | 5e-55 | 31.66% (499) | PUTATIVE AMP-binding enzyme, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1462c | fadD12 | 0.0 | 71.82% (543) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_2427 | - | 0.0 | 71.99% (539) | acyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv1427c | fadD12 | 0.0 | 71.82% (543) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 1e-114 | 41.94% (546) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4340c | - | 1e-109 | 41.67% (540) | acyl-CoA synthetase |
| M. marinum M | MMAR_2233 | fadD12 | 0.0 | 70.50% (556) | long-chain-fatty-acid--CoA ligase FadD12 |
| M. avium 104 | MAV_3349 | - | 0.0 | 73.01% (452) | acyl-CoA synthetase |
| M. smegmatis MC2 155 | MSMEG_0304 | - | 0.0 | 70.83% (545) | acyl-CoA synthetase |
| M. ulcerans Agy99 | MUL_4827 | fadD12_2 | 1e-107 | 41.07% (543) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_4225 | - | 0.0 | 70.26% (548) | acyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1462c|M.bovis_AF2122/97 -----------------MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAA
Rv1427c|M.tuberculosis_H37Rv -----------------MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAA
MMAR_2233|M.marinum_M ---------------MAPRIDQILGLITTLARSGLIAPMRPDRYLKIAAA
MAV_3349|M.avium_104 --------------------------------------------------
MSMEG_0304|M.smegmatis_MC2_155 ---------MGLLDRITDPLIDTVGMVTTMRRAGLIAPLRPDKYLRIVAA
Mflv_2427|M.gilvum_PYR-GCK ----------------MSSAADQFGLLATLWRARLIAPMRPDRYLRMGLA
Mvan_4225|M.vanbaalenii_PYR-1 -------------------MADPLGLLATLWRARLIAPMRPDRYLRMGLA
TH_4130|M.thermoresistible__bu -------------------MAKTIDTLRTLTRAGLIAPLRPDKYLRMTAA
MUL_4827|M.ulcerans_Agy99 ----------------MMAAGVVTTAARALLGSGLLSPSSPAAALRLVRE
MLBr_02546|M.leprae_Br4923 ---------MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVA
MAB_4340c|M.abscessus_ATCC_199 MSITAERPLFSKLQTLAKRGGAELHYLRKVIEAGMLKLDPPNVLAGLVRD
Mb1462c|M.bovis_AF2122/97 MRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERGNALAAALQA
Rv1427c|M.tuberculosis_H37Rv MRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERGNALAAALQA
MMAR_2233|M.marinum_M MRREGMGFTAGFAAAAQRCPDRPGLVDELGTLTWRQLDERSNALAAALQA
MAV_3349|M.avium_104 --------------------------------------------------
MSMEG_0304|M.smegmatis_MC2_155 MARENMSVTSGFASAAQRCPDRPGLVDELGTLTWREIDQQADALAAGLQA
Mflv_2427|M.gilvum_PYR-GCK MRRAGLTATVGFAAAAQRCPDRPGIIDELGTLTWKQLDDRCDALGVALQK
Mvan_4225|M.vanbaalenii_PYR-1 MRRAGLTATVGFAAAAQRCPDLPGIIDELGTLTWKQLDDRCDALAAALQK
TH_4130|M.thermoresistible__bu VRRTGVSVTVGFAVAAQRCGDRIGLVDEIGELTWRELDDECNALAAALQD
MUL_4827|M.ulcerans_Agy99 LYRGGTNLYTPLAIAAARWPERTAIVDDDGALSYREIQTMTESVAGELTL
MLBr_02546|M.leprae_Br4923 MRKWG-DLAMLPAMPARRSPHRAALIDEEGTLTYKELDRAAHALANGLIA
MAB_4340c|M.abscessus_ATCC_199 FYRFG-EIGAVPAFGAHRSPSRTAIIDDEGSITYAELNDAVNALAHGLNR
Mb1462c|M.bovis_AF2122/97 LPAG-------PPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGP
Rv1427c|M.tuberculosis_H37Rv LPAG-------PPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGP
MMAR_2233|M.marinum_M LPAG-------SPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP
MAV_3349|M.avium_104 --------------MIGIMCRNHRGFVEAPVAADRIGADIVLLNTSFAGP
MSMEG_0304|M.smegmatis_MC2_155 LSGG-------APRVLGIMARNHRGFVLSLIAANRIGADVLLLNTSFSGP
Mflv_2427|M.gilvum_PYR-GCK E----------KPKTVAVMCRNHRGFVEALVAANRIGADVLLLNTSFAGP
Mvan_4225|M.vanbaalenii_PYR-1 H----------TPRTVAVMCRNHRGFVEALVGANRIGADVLLLNTSFAGP
TH_4130|M.thermoresistible__bu RAAGQGKDGGKGRGAIGIMCRNHRGFIEALVAADRIGATVLLLNTSFAGP
MUL_4827|M.ulcerans_Agy99 AGIG-------PGQAVGVMCRNGRNFVAAAFAAGLVGADVVLVNTEFRAT
MLBr_02546|M.leprae_Br4923 KGVR-------GGDGIAILARNHRWFVIANYGCARVGARIILLNSEFSGP
MAB_4340c|M.abscessus_ATCC_199 LGIK-------GGDGVAILARNHRWFIIANYAAHRAGARVILLNTDFSGP
:.::.** * *: : . ** ::*:*: * ..
Mb1462c|M.bovis_AF2122/97 ALAEVVTREGVDTVVYDEEFSATVDRALAEKPQA-TRIVAWTD------E
Rv1427c|M.tuberculosis_H37Rv ALAEVVTREGVDTVVYDEEFSATVDRALAEKPQA-TRIVAWTD------E
MMAR_2233|M.marinum_M ALADVVAREGVDTVIYDEEFTATVDRAFDGRPQA-TRIVAWSD------G
MAV_3349|M.avium_104 ALADVITREGVDAVIYDEEFTATVDRALAGRPDA-IRIVAWTD------T
MSMEG_0304|M.smegmatis_MC2_155 ALAEVVSREKVDAVIYDEEFTDTVDRALAGAPEAPTRIVAWTDT-----A
Mflv_2427|M.gilvum_PYR-GCK AMAEVVEREGADIVIYDQEFTETVDRALADTCGA-RRIVAWVDDPA---Q
Mvan_4225|M.vanbaalenii_PYR-1 AMAEVIEREGADIVIYDQEFTATVDRALRDVPGT-TRILAWTD--A---D
TH_4130|M.thermoresistible__bu ALAEVVDREGVDTIVYDEEFTDIVDRALADRPTA-TRILAWVDEPASGPA
MUL_4827|M.ulcerans_Agy99 ALAAALEAHQMRVMLCDDEFVDQVAGTGES--------VLVID-------
MLBr_02546|M.leprae_Br4923 QIKEVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEP--PG
MAB_4340c|M.abscessus_ATCC_199 QTKEVAEREGARVLIYDAEYAEFLDGYSPELGRIMALPTNPDNPDQ--PA
. . :: * *: : :
Mb1462c|M.bovis_AF2122/97 DHDLTVEKLVAAHAGRRPEH---TGSHGKVILLTSGTTGTPKGARHSGG-
Rv1427c|M.tuberculosis_H37Rv DHDLTVEKLVAAHAGRRPEH---TGSHGKVILLTSGTTGTPKGARHSGG-
MMAR_2233|M.marinum_M QHDLTVEQLVNAHLGDQPER---TGRTGRLILLTSGTTGTPKGAKHSGGS
MAV_3349|M.avium_104 EHQHTVDKLIASKAGAQPIR---TGRKGKMILLTSGTTGTPKGAKQSGGN
MSMEG_0304|M.smegmatis_MC2_155 AHDVTVAALTEKFAGRQPQR---GGQKSKVILLTSGTTGTPKGAKHSGG-
Mflv_2427|M.gilvum_PYR-GCK AGTATVEALIDAHLGQRPQP---ATRKSDVILLTSGTTGSPKGAKRSAGS
Mvan_4225|M.vanbaalenii_PYR-1 DGSTTLEALIDAHLGQRPEP---ATRKSDIILLTSGTTGTPKGAKRSAGS
TH_4130|M.thermoresistible__bu LPHPTVADLVAEHRGRRPAKPAAGDEGSRIILLTSGTTGTPKGAR-AASS
MUL_4827|M.ulcerans_Agy99 ------PSTVTARDCARPKV----APSGRIVLLTSGTTGVPKGVPRKPKV
MLBr_02546|M.leprae_Br4923 STDETLAELIARSSSAPAPK---VRKRASIIILTSGTTGTPKGANRNTPA
MAB_4340c|M.abscessus_ATCC_199 STDETIASVIKRNSTSPAPR---PSKYSSLVILTSGTTGTPKGAPRKLAL
. . :::******* ***.
Mb1462c|M.bovis_AF2122/97 --GIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTR
Rv1427c|M.tuberculosis_H37Rv --GIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTR
MMAR_2233|M.marinum_M G-GIGTLKAILDRTPWRAEQPIVIVAPMFHAWGFSQLVLAASLACTIVTR
MAV_3349|M.avium_104 A-GIGTLKAILDRTPWRAEEPVVIVAPMFHAWGFSQLLLAASFACPVITR
MSMEG_0304|M.smegmatis_MC2_155 --GPEILKAILDRTPWRAEEPVVIVAPMFHAWGFSQLAFAASMACTIITR
Mflv_2427|M.gilvum_PYR-GCK G-GSGDLKAVLDRTPWRAEEPIVIAAPMFHAWGFSQLLFAALLACPIVTR
Mvan_4225|M.vanbaalenii_PYR-1 G-GASDLKAVLDRTPWRAGEPIVIAAPMFHAWGFSQLLFAALLACPIVTR
TH_4130|M.thermoresistible__bu G-GAGELAAILGRVPWRAEQTTVIAAPMFHAWGYSQLLFSALLACTIVTR
MUL_4827|M.ulcerans_Agy99 SSGIGVSATLLERTRLRVGSRMTLATPMFHGLGFGMLVLTISLGGTVLTR
MLBr_02546|M.leprae_Br4923 S--LAPLGGILSKVPFRAHEVTLLPAPMFHALGYLHATLAMFLGSTLVLR
MAB_4340c|M.abscessus_ATCC_199 T--LAPVGGMFSHVPFRSGEVTSVPAPMFHALGYLHQSLALTLGCTLILR
:: :. * . : :****. *: :: :. .:: *
Mb1462c|M.bovis_AF2122/97 RRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAA
Rv1427c|M.tuberculosis_H37Rv RRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAA
MMAR_2233|M.marinum_M RKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLNRYSGRTLRFAA
MAV_3349|M.avium_104 RKFDPEATLDLIDRHRATGLVVVPVMFDRIMDLPAEVRRRYECRSLRFAA
MSMEG_0304|M.smegmatis_MC2_155 RKFDPEATLELVDRHRATGLCVVPVMFDRIMELPEDVLNRYDGRSLRFAA
Mflv_2427|M.gilvum_PYR-GCK RKFDPAATLALVDKYRATGLAVVPVMFDRIMDLPDEVRNRYSGRSLRFAT
Mvan_4225|M.vanbaalenii_PYR-1 RKFDPEATLALIDRHRATGLAVVPVMFDRIMELPAEVRNRYSGRSLRFAT
TH_4130|M.thermoresistible__bu RRFDPEATLQLVDRYRATGLVVVPVMLDRIMELPADVRDRYSGRSLRFVT
MUL_4827|M.ulcerans_Agy99 RHFDAEATLAQTSLHRADGLSVVPIMLARILDLPDQVRARNPLPCLRAVI
MLBr_02546|M.leprae_Br4923 RRFKPATVLEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVF
MAB_4340c|M.abscessus_ATCC_199 RKFKPENVLADVEKFKVTAIVVVPVMLNRLLNALDELSVKPDLSSLRIVF
*:*.. .* . .:. .: ***:*: *::: .: : ** .
Mb1462c|M.bovis_AF2122/97 ASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAG
Rv1427c|M.tuberculosis_H37Rv ASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAG
MMAR_2233|M.marinum_M ASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTAG
MAV_3349|M.avium_104 ASGSRMRPDVVVAFMDEFGDVIYNNYNATEAGMIATATPADLRAAPDTAG
MSMEG_0304|M.smegmatis_MC2_155 ASGSRMRPDVVIAFMDRFGDVIYNNYNATEAGMIATATPADLRAAPDTAG
Mflv_2427|M.gilvum_PYR-GCK ASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPEDLRAAPDTAG
Mvan_4225|M.vanbaalenii_PYR-1 ASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPADLRAAPDTAG
TH_4130|M.thermoresistible__bu ASGSRMRPDVVLDFMDRFGDVIYNNYNATEAGMIATATPADLRAAPSTAG
MUL_4827|M.ulcerans_Agy99 SSGDRLDPSLARRFMEAYGDVLYNLYGSTEVGIGALATPAELRDWPETVG
MLBr_02546|M.leprae_Br4923 VSGSQLGAELATRALEELGPVIYNMYGSTEIAFATIAGPKDLQINSATVG
MAB_4340c|M.abscessus_ATCC_199 VSGSQLGGELASRAMDTLGPVIYNLYGSTEVAFATIARPQDLAINPSTVG
**.:: .:. :: * *:** *.:** .: : * * :* . *.*
Mb1462c|M.bovis_AF2122/97 RPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFM
Rv1427c|M.tuberculosis_H37Rv RPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFM
MMAR_2233|M.marinum_M RPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFM
MAV_3349|M.avium_104 RPAGGTEIRILDPEFNELPAGEVGTIYVRNNTQFDGYTSGSSKDFHEGFM
MSMEG_0304|M.smegmatis_MC2_155 RPAEGTEIRILDGDLRDLPTGEVGTIYVRNSTQFDGYTSGTTKDFHEGFM
Mflv_2427|M.gilvum_PYR-GCK KAADGTELRILDAEHRELPTGEVGQIFVRSGTLFDGYTSGSTKDFHDGFM
Mvan_4225|M.vanbaalenii_PYR-1 RAADGTELRILDAEHRDVPTGEVGQIFVRSSTLFDGYTSGTTKAFHDGFM
TH_4130|M.thermoresistible__bu KPADGTEIRILDDALRPVPTGEVGQIFVRSNTLFDGYTSGTTKDFHEGFM
MUL_4827|M.ulcerans_Agy99 RPVAGCPVRIFDRNGRPVGARVTGRIFVGGELNSDGYSGGGGKAVIDGMA
MLBr_02546|M.leprae_Br4923 PVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGGGGKQIIDGLL
MAB_4340c|M.abscessus_ATCC_199 PVVKGATVKILDDEGKPVSQGTVGRIFVSNAIPFDGYTGGGHKQIIDGLM
. * ::*:* : .* *:* . :**:.* * . *:
Mb1462c|M.bovis_AF2122/97 SSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAA
Rv1427c|M.tuberculosis_H37Rv SSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAA
MMAR_2233|M.marinum_M SSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAA
MAV_3349|M.avium_104 SSGDLGYLDSAGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPDVAEAA
MSMEG_0304|M.smegmatis_MC2_155 CSGDVGRLDDAGRLFVVGRDDEMIVSGGENVYPIEVEKVLTTHPAVAEAA
Mflv_2427|M.gilvum_PYR-GCK ASGDLGYLDDAGRLFVVGRDDEMIVSGGENVYPIEVEKTLMSHPEVAEAT
Mvan_4225|M.vanbaalenii_PYR-1 ASGDMGYLDGAGRLFVVGRDDEMIVSGGENVYPIEVEKTLTTHAAVAEAA
TH_4130|M.thermoresistible__bu ASGDLGRLDEDGRLFVVGRDDEMIVSGGENVYPIEVEQVLARHPDVAEAT
MUL_4827|M.ulcerans_Agy99 STGDMGYLDESGRLYIVGREDDMIVSGGENVYPRSLENALASHPDVAENA
MLBr_02546|M.leprae_Br4923 SSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEAT
MAB_4340c|M.abscessus_ATCC_199 SSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPEVIEAT
.:**:* :* . *:: **:*:********::* .:*. : *. * * :
Mb1462c|M.bovis_AF2122/97 VIGVDDQQYGQRLAAFVVLKP----GVSATPETLKQHVRDNLANYKVPRD
Rv1427c|M.tuberculosis_H37Rv VIGVDDQQYGQRLAAFVVLKP----GVSATPETLKQHVRDNLANYKVPRD
MMAR_2233|M.marinum_M VIGVDDEQYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPRE
MAV_3349|M.avium_104 VIGVDDEQYGQRLAAFVVLAP----EARATPEALKQHVRDNLANYKVPRE
MSMEG_0304|M.smegmatis_MC2_155 VIGVDDEQFGQRLAAFVVLSG------DATVDDLKSHVRDNLANYKVPRD
Mflv_2427|M.gilvum_PYR-GCK VLGVEDSEYGQRLAAFVVLTD----GSGLTPEDLKQHVRANLANYKVPRD
Mvan_4225|M.vanbaalenii_PYR-1 VLGVDDEQYGQRLAAFVVPAA----GASVTVEELKQHVRENLANYKVPRD
TH_4130|M.thermoresistible__bu VIGVDDEQFGQRLAAFVVLRD----GAGATPDGLKQHVRDNLANYKVPRS
MUL_4827|M.ulcerans_Agy99 VIGVADEQFGQRLAAFVVARP----GCDIDADAIRDYLKGRVSRFEQPRD
MLBr_02546|M.leprae_Br4923 AIGVDDKEWGARLRAFVVKKQ----DATIDEDAIKAYVRDHLARYKVPRE
MAB_4340c|M.abscessus_ATCC_199 ALGVDDPEWGARLRAFVVRHP----DSTVDADGIRAYVRDNLARYKVPRD
.:** * ::* ** **** : :: ::: .::.:: **.
Mb1462c|M.bovis_AF2122/97 IAVLDELPRGITGKILRTELQSRVGS----
Rv1427c|M.tuberculosis_H37Rv IAVLDELPRGITGKILRTELQSRVGS----
MMAR_2233|M.marinum_M IAVLDELPRGSTGKILRAELQAKVCGT---
MAV_3349|M.avium_104 ISVLDELPRSSTGKILRADLRARVGG----
MSMEG_0304|M.smegmatis_MC2_155 ITILDELPRNSTGKIARRELQEKVNG----
Mflv_2427|M.gilvum_PYR-GCK ITILPELPRGSTGKILRNELRGS-------
Mvan_4225|M.vanbaalenii_PYR-1 ITIMAELPRGSTGKILRNELRGR-------
TH_4130|M.thermoresistible__bu ISVLDELPRGSTGKILRTELQARAQSG---
MUL_4827|M.ulcerans_Agy99 IYLVSSIPRNPAGKVLRKQLASYAEPEAQS
MLBr_02546|M.leprae_Br4923 VIFLEELPRNPTGKVLKRELRDFEVH----
MAB_4340c|M.abscessus_ATCC_199 VVFLDVLPRNPSGKILKRELRELEV-----
: .: :**. :**: : :*