For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAASAEGPSAAGRPRAAKSTSRPAKLSRDAIVDGALTFLDREGWDSLTINALATQLGTKGPSLYNHVVSL EDLRGAVRVRVIDDIIMMLNRVGEGRSRDDAVLVMAGAYRSYAHHHPGRYSAFTRMPPGGEDPEYAAATR AAAAPVIAVLSSYGLEGEQAFHAALEFWSALHGFVLLEMTGLMEEIDTDAVFSDMVLRLAAGMEKRISHT GAESL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1010 | - | - | 100% (215) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4906 | - | 1e-06 | 27.27% (176) | transcriptional regulator |
| M. marinum M | MMAR_4304 | - | 3e-06 | 26.56% (192) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0700 | - | 7e-95 | 86.60% (194) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5079 | - | 2e-79 | 77.96% (186) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0681 | - | 7e-95 | 86.60% (194) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3852c | - | 2e-57 | 55.22% (201) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4494 | - | 1e-100 | 83.73% (209) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1397 | - | 2e-85 | 80.65% (186) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1893 | - | 9e-87 | 77.50% (200) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_0762 | - | 1e-120 | 100.00% (215) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1278 | - | 1e-80 | 78.38% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5079|M.gilvum_PYR-GCK ---------------MAARPPRTAKLSRDSIVNAALTFLDREGWDALTIN
Mvan_1278|M.vanbaalenii_PYR-1 ---------------MAVRPPRTAKLSRDAIVNAALTFLDREGWDALTIN
MMAR_1010|M.marinum_M MAASAEGPSAAGRPRAAKSTSRPAKLSRDAIVDGALTFLDREGWDSLTIN
MUL_0762|M.ulcerans_Agy99 MAASAEGPSAAGRPRAAKSTSRPAKLSRDAIVDGALTFLDREGWDSLTIN
Mb0700|M.bovis_AF2122/97 -------------------MARPAKLSRESIVEGALTFLDREGWDSLTIN
Rv0681|M.tuberculosis_H37Rv -------------------MARPAKLSRESIVEGALTFLDREGWDSLTIN
MAV_4494|M.avium_104 MAAQPEPPTAAGRQRAGRPAARPAKLSREGIIDGALTFLDREGWDALTIN
MSMEG_1397|M.smegmatis_MC2_155 ----MRA-------------TRTTRLSRDTIVNAALTFLDREGWDALTIN
TH_1893|M.thermoresistible__bu VNTQMSAGPGGAPGARTKSPARAGRLSRDTIVNAALTFLDREGWDALTIN
MAB_3852c|M.abscessus_ATCC_199 -------MTTEPATAHRRTPARATRLNRDAVVNAALSFLDRAGWDALTIN
.*. :*.*: :::.**:**** ***:****
Mflv_5079|M.gilvum_PYR-GCK ALANQLGTKGPSLYNHVHSLDDLRRTVRMRVVGDIIDMLNTVAQGRNPDD
Mvan_1278|M.vanbaalenii_PYR-1 ALANQLGTKGPSLYNHVHSLDDLRRTVRMHVVGDIIEMLNTVGKGRTPDD
MMAR_1010|M.marinum_M ALATQLGTKGPSLYNHVVSLEDLRGAVRVRVIDDIIMMLNRVGEGRSRDD
MUL_0762|M.ulcerans_Agy99 ALATQLGTKGPSLYNHVVSLEDLRGAVRVRVIDDIIMMLNRVGEGRSRDD
Mb0700|M.bovis_AF2122/97 ALATQLGTKGPSLYNHVDSLEDLRRAVRIRVIDDIITMLNRVGAGRARDD
Rv0681|M.tuberculosis_H37Rv ALATQLGTKGPSLYNHVDSLEDLRRAVRIRVIDDIITMLNRVGAGRARDD
MAV_4494|M.avium_104 ALATQLGTKGPSLYNHVDSLEDLRRAVRIRVIDDIITMLNRVGEGRARDD
MSMEG_1397|M.smegmatis_MC2_155 ALANQLGTKGPSLYNHVHSLDDLRRTVRMRVIDDIISMLNRVGEGRTRDD
TH_1893|M.thermoresistible__bu ALATQLGTKGPSLYNHVQSLDDLRRSVRMRVVDDIIGMLNAAGQGRTRDD
MAB_3852c|M.abscessus_ATCC_199 ALAVELGTKGPSLYNHVDSLDDLRHEVRDRVLAEIVGMLHTVSSGRSSED
*** :************ **:*** ** :*: :*: **: .. ** :*
Mflv_5079|M.gilvum_PYR-GCK AVVVMASAYRSYAHHHPGRYSAFTRMPLGGGDDPEFTEVTRAAAAPVIAV
Mvan_1278|M.vanbaalenii_PYR-1 AVMVMASAYRSYAHHHPGRYSAFTRMPLGG-DDPEFTEATRAAAAPVISV
MMAR_1010|M.marinum_M AVLVMAGAYRSYAHHHPGRYSAFTRMPPGG-EDPEYAAATRAAAAPVIAV
MUL_0762|M.ulcerans_Agy99 AVLVMAGAYRSYAHHHPGRYSAFTRMPPGG-EDPEYAAATRAAAAPVIAV
Mb0700|M.bovis_AF2122/97 AVLVMAGAYRSYAHHHPGRYSAFTRMPLGG-DDPEYTAATRGAAAPVIAV
Rv0681|M.tuberculosis_H37Rv AVLVMAGAYRSYAHHHPGRYSAFTRMPLGG-DDPEYTAATRGAAAPVIAV
MAV_4494|M.avium_104 AVLVMAGAYRSYAHHHPGRYSAFTRMPLGG-DDPEYTAATRGAAAPVISV
MSMEG_1397|M.smegmatis_MC2_155 AVIAMASAYRSYAHHHPGRYSAFTRMPFGD-DDPEYSAATKAAAAPVIEV
TH_1893|M.thermoresistible__bu AVLAMASAYRSYAHHHPGRYSAFTRMPLGG-DDPEFSAAARAAAGPVIAV
MAB_3852c|M.abscessus_ATCC_199 AILAMAGAYRSYAHHHPGRYAALTRMPFLD-AVNRPTIDARELAKPATEA
*::.**.*************:*:**** . . : :: * *. .
Mflv_5079|M.gilvum_PYR-GCK LSSYGLDDEAGFYAALEFWSAMHGFVLLEMTGVMN--GIDTDAVFTDMVM
Mvan_1278|M.vanbaalenii_PYR-1 LETFGLESESAFYAALEFWSAMHGFVLLEMTGVMS--GIDTDAVFTDMVA
MMAR_1010|M.marinum_M LSSYGLEGEQAFHAALEFWSALHGFVLLEMTGLME--EIDTDAVFSDMVL
MUL_0762|M.ulcerans_Agy99 LSSYGLEGEQAFHAALEFWSALHGFVLLEMTGLME--EIDTDAVFSDMVL
Mb0700|M.bovis_AF2122/97 LSSYGLDGEQAFYAALEFWSALHGFVLLEMTGVMD--DIDTDAVFTDMVL
Rv0681|M.tuberculosis_H37Rv LSSYGLDGEQAFYAALEFWSALHGFVLLEMTGVMD--DIDTDAVFTDMVL
MAV_4494|M.avium_104 LSSYGLDGEEAFHAALEFWSALHGFVLLEMTGVMD--DIDTDALFSDMVL
MSMEG_1397|M.smegmatis_MC2_155 LASFGLEGEQAFYAALEFWSALHGFVLLEMTGVMD--DVDTDAVFTDMLL
TH_1893|M.thermoresistible__bu LGSYGLEGEEAFYAALEFWSALHGFVLLEMTGVMD--DVDSDKVFTDMVL
MAB_3852c|M.abscessus_ATCC_199 IGVYGLNEDTAFHAGVELWAAMHGFVMLEMTGFMAGIEMDPDTAFAEMVH
: :**: : .*:*.:*:*:*:****:*****.* :*.* *::*:
Mflv_5079|M.gilvum_PYR-GCK RLAAGMQTR---------
Mvan_1278|M.vanbaalenii_PYR-1 RLAAGMQLR---------
MMAR_1010|M.marinum_M RLAAGMEKRISHTGAESL
MUL_0762|M.ulcerans_Agy99 RLAAGMEKRISHTGAESL
Mb0700|M.bovis_AF2122/97 RLAAGMERRTTHGGTAST
Rv0681|M.tuberculosis_H37Rv RLAAGMERRTTHGGTAST
MAV_4494|M.avium_104 RLAAGLERRTAHG-----
MSMEG_1397|M.smegmatis_MC2_155 RLASGMERREA-------
TH_1893|M.thermoresistible__bu RLAAGMEKRS--------
MAB_3852c|M.abscessus_ATCC_199 RFASGLAERK--------
*:*:*: *