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TVIRAALTQATWTGDKESMLAKHERFVAQAAARGAQVICFQELFYGPYFGIVQDKKYYGYAEPVPGPVTE RFAKLAREHRMVLVLPVYEQEQPGVLYNTAAVVDSDGRYLGKYRKHHIPHLDRFWEKFYFRPGNLGYPVF DTAVGKIGVYICYDRHFPEGWRNYGLAGAELVFNPSATKPGLSNRLWELEQPAAAAANQYFVGANNRIGA ESGEFGDQAVSFYGSSYFVDPRGNYVGEIGSATDEEIVIRDLDLSLVRQVRDDWQFYRDRRPDTYGPIIA P*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2818c | - | - | 100% (282) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2545c | - | 5e-27 | 31.08% (296) | nitrilase/cyanide hydratase and apolipoprotein |
| M. abscessus ATCC 19977 | MAB_0819 | - | 6e-17 | 26.84% (272) | carbon-nitrogen hydrolase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0490c | - | 8e-10 | 24.34% (267) | hypothetical protein Mb0490c |
| M. gilvum PYR-GCK | Mflv_0095 | - | 1e-09 | 26.32% (266) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. tuberculosis H37Rv | Rv0480c | - | 8e-10 | 24.34% (267) | amidohydrolase |
| M. leprae Br4923 | MLBr_02449 | - | 6e-10 | 25.00% (280) | putative hydrolase |
| M. marinum M | MMAR_0805 | - | 1e-10 | 26.55% (275) | amidohydrolase |
| M. avium 104 | MAV_4670 | - | 2e-14 | 26.05% (261) | carbon-nitrogen hydrolase |
| M. smegmatis MC2 155 | MSMEG_3555 | - | 1e-135 | 77.94% (281) | hydrolase |
| M. thermoresistible (build 8) | TH_0873 | - | 2e-10 | 26.30% (270) | POSSIBLE AMIDOHYDROLASE |
| M. ulcerans Agy99 | MUL_4548 | - | 7e-11 | 26.24% (282) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_1224 | - | 2e-21 | 30.72% (293) | Nitrilase/cyanide hydratase and apolipoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0805|M.marinum_M -------------------------------MRIALAQILSGTDPTANLE
MUL_4548|M.ulcerans_Agy99 -------------------------------MRIALAQILSGTDPTANLE
MLBr_02449|M.leprae_Br4923 -------------------------------MRIALAQILSGTDPVANLR
Mb0490c|M.bovis_AF2122/97 MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSGTDPAANLQ
Rv0480c|M.tuberculosis_H37Rv -------------------------------MRIALAQIRSGTDPAANLQ
MAV_4670|M.avium_104 -------------------------------MRIALAQILSGTDPAANLA
Mflv_0095|M.gilvum_PYR-GCK ---------------------------MRSGMRIALAQIQSSTDPAANLT
TH_0873|M.thermoresistible__bu -------------------------------MRIALAQIRSGTDPSANLN
MAB_2818c|M.abscessus_ATCC_199 ----------------------------MTVIRAALTQATWTGDKESMLA
MSMEG_3555|M.smegmatis_MC2_155 ----------------------------MTVIRAAITQVEWTGDEESMVA
Mvan_1224|M.vanbaalenii_PYR-1 ------------------------------MTTLAAVSANFTRDLEQNYA
* .. *
MMAR_0805|M.marinum_M LVRDYAERAADAGARLVVFPEATMCR-FGVPLG------------PVAQP
MUL_4548|M.ulcerans_Agy99 LVRDYAERAADAGARLVVFPEATMCR-FGVPLG------------PVAQP
MLBr_02449|M.leprae_Br4923 LVREYTGQATDAGATLVVFPEATMCR-FGVPLG------------PVAEP
Mb0490c|M.bovis_AF2122/97 LVGKYAGEAATAGAQLVVFPEATMCR-LGVPLR------------QVAEP
Rv0480c|M.tuberculosis_H37Rv LVGKYAGEAATAGAQLVVFPEATMCR-LGVPLR------------QVAEP
MAV_4670|M.avium_104 LVGEYTRRAAGAGARLVVFPEATMCR-FGVPLA------------PIAEP
Mflv_0095|M.gilvum_PYR-GCK LVEEYTRRAVDAGASLVLFPEATMVR-FGVPLG------------GVAEP
TH_0873|M.thermoresistible__bu LVEEYTRRAAATGAGLVLFPEATMCR-FGVSLK------------PVAEP
MAB_2818c|M.abscessus_ATCC_199 KHERFVAQAAARGAQVICFQELFYGPYFGIVQDK--------KYYGYAEP
MSMEG_3555|M.smegmatis_MC2_155 RHEALARRAAEAGAQIICFQELFHGPYFGIVQDA--------KYYEYAQA
Mvan_1224|M.vanbaalenii_PYR-1 LIASLADEARHRGVDFLTLPEAAIGGYLSSLGNHGDTVRTTARSLPPAIR
. .* *. .: : * :. *
MMAR_0805|M.marinum_M LDGPWANGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDD
MUL_4548|M.ulcerans_Agy99 LDGPWANGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDD
MLBr_02449|M.leprae_Br4923 IDGPWANGVRQIATEAGITIIAGIFTPADDGRVMNTLIAAGPGTPNQPDT
Mb0490c|M.bovis_AF2122/97 VDGPWANGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDA
Rv0480c|M.tuberculosis_H37Rv VDGPWANGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDA
MAV_4670|M.avium_104 VDGPWADGVRRIATEANVTVIAGMFTPSGDGRVKNTLLVAN--SDDQAVT
Mflv_0095|M.gilvum_PYR-GCK FDGPWANAVRDIAARAGIVVVAGMFVPSDDGRSFNTLLATGPGVEAR---
TH_0873|M.thermoresistible__bu LDGPWATAVREIAAGAGVVVVAGMFTPSGDGRVTNTLLATGPGVAAH---
MAB_2818c|M.abscessus_ATCC_199 VPGPVTERFAKLAREHRMVLVLPVYEQEQPGVLYNTAAVVD--SDGRYLG
MSMEG_3555|M.smegmatis_MC2_155 VPGPLTERFSVLAKDLGVVLILPVYEEEMPGVYYNTAAVID--SDGKYLG
Mvan_1224|M.vanbaalenii_PYR-1 LDGPEIARVQQIVGDLVVAIGFCELADDGHTRYNAAAVLDG----STVYG
. ** . :. :.: : .
MMAR_0805|M.marinum_M HYHKIHLYDAFGFAESRTVAPGHE--PVVITVDD----VQVGLTVCYDIR
MUL_4548|M.ulcerans_Agy99 HYHKIHLYDAFGFAESRTVAPGHE--PVVITVDD----FQVGLTVCYDIR
MLBr_02449|M.leprae_Br4923 HYHKIHLYDAFGFTESRTVTAGHE--PVVITVDD----VQVGLTICYDIR
Mb0490c|M.bovis_AF2122/97 HYHKIHLYDAFGFTESRTVAPGRE--PVVVVVDG----VRVGLTVCYDIR
Rv0480c|M.tuberculosis_H37Rv HYHKIHLYDAFGFTESRTVAPGRE--PVVVVVDG----VRVGLTVCYDIR
MAV_4670|M.avium_104 HYDKIHLYDAFGFTESRTVAPGRE--PVVVGVDG----VRVGLSVCYDIR
Mflv_0095|M.gilvum_PYR-GCK -YDKIHLYDAFGFLESKTVAPGRE--PVVISVDTESGPVTVGLTLCYDIR
TH_0873|M.thermoresistible__bu -YHKIHLYDAYGFTESRTVAPGSE--PVTIDVGG----VRVGLTTCYDIR
MAB_2818c|M.abscessus_ATCC_199 KYRKHHIPHLDRFWEKFYFRPGNLGYPVFDTAVG-----KIGVYICYDRH
MSMEG_3555|M.smegmatis_MC2_155 KYRKNHIPNVDRFWEKFYFKPGNLGYPIFDTAVG-----KVGVYICYDRH
Mvan_1224|M.vanbaalenii_PYR-1 SYRKVHQP----LGEGMSYSAGSG-YGVFDTPIG-----RVGLQICYDKA
* * * : * .* : :*: ***
MMAR_0805|M.marinum_M FPALYTELARRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAA
MUL_4548|M.ulcerans_Agy99 FPALYTELARRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAA
MLBr_02449|M.leprae_Br4923 FPALYTELARRGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAV
Mb0490c|M.bovis_AF2122/97 FPALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAA
Rv0480c|M.tuberculosis_H37Rv FPALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAA
MAV_4670|M.avium_104 FPELYTELARRGAQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAA
Mflv_0095|M.gilvum_PYR-GCK FPELYVELADRGAEIITAHASWGTGPGKLEQWTLLARARAIDTSSVVAAV
TH_0873|M.thermoresistible__bu FPELYVELARRGAELLTVHASWGSGPGKLEQWTLLARARALDTTCVVAAV
MAB_2818c|M.abscessus_ATCC_199 FPEGWRNYGLAGAELVFNPSATKPGLS-NRLWELEQPAAAAANQYFVGAN
MSMEG_3555|M.smegmatis_MC2_155 FPEGWREFGLAGAEIVFNPSATKPGLS-NRLWELEQPAAAANNQYFVAAN
Mvan_1224|M.vanbaalenii_PYR-1 FPEAARIMALRGAQVIASLSAWPAARTATAENLQDDRWTYRFNLFDTARA
** . **::: :: .. . .
MMAR_0805|M.marinum_M GQADPGDTASDPGGGSGAPRGVGGSLVASPLGEVVASAGSD--PQLVVAD
MUL_4548|M.ulcerans_Agy99 GQADPGDTASDPGGGSGAPRGVGGSLVTSPLGEVVASAGSD--PQLVVAD
MLBr_02449|M.leprae_Br4923 GQADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAGTE--SKLVVAD
Mb0490c|M.bovis_AF2122/97 GQADPGDARTGVGASSAAPTGVGGSLVASPLGEVVVSAGTQ--PQLLVAD
Rv0480c|M.tuberculosis_H37Rv GQADPGDARTGVGASSAAPTGVGGSLVASPLGEVVVSAGTQ--PQLLVAD
MAV_4670|M.avium_104 GQADPGGSLS----ASGAPTGVGGSLVASPLGEVVASAGAQ--PQLVLAD
Mflv_0095|M.gilvum_PYR-GCK GQAYPGDEIAALG-----PTGVGGSLVASALGEVLASAGDD--PELLVCD
TH_0873|M.thermoresistible__bu GQAYPGDEIAAQG-----PTGVGGSLVASATGEVLAAAGPE--PELLVAD
MAB_2818c|M.abscessus_ATCC_199 --NRIGAESGEFG--DQAVSFYGSSYFVDPRGNYVGEIGSATDEEIVIRD
MSMEG_3555|M.smegmatis_MC2_155 --NRIGTESEEFG--DDAVTFYGSSYFVDPRGNYVGEVASENAEEIVIRD
Mvan_1224|M.vanbaalenii_PYR-1 LDNQVFWVASNQSGTFGSLRYVGNAKVVDPGGNILATTLLG--SGMAVAE
*.: .... *: : : : :
MMAR_0805|M.marinum_M IDLAK-VGAARDNIGVLRNQSRFTQTDKAQSRR-------
MUL_4548|M.ulcerans_Agy99 IDLAK-VGAARDNIGMLRNQSRFTQTDKAQSRR-------
MLBr_02449|M.leprae_Br4923 IDVDN-VTTARENIAVLRNRSHFA----------------
Mb0490c|M.bovis_AF2122/97 IDVDN-VAAARDRIAVLRNQTDFVQIDKAQSRG-------
Rv0480c|M.tuberculosis_H37Rv IDVDN-VAAARDRIAVLRNQTDFVQIDKAQSRG-------
MAV_4670|M.avium_104 IDVDR-VAQARKTIAALSNRSDFAQVGRAESVG-------
Mflv_0095|M.gilvum_PYR-GCK VDLEA-ARKARQTVAVMQNRSGFAHRGKAESRG-------
TH_0873|M.thermoresistible__bu LDLDA-ARRARDTIAVLRNRSDVAQWGKAESVG-------
MAB_2818c|M.abscessus_ATCC_199 LDLSL-VRQVRDDWQFYRDRRPDTYGPIIAP---------
MSMEG_3555|M.smegmatis_MC2_155 LDLAM-VRAVRNDWQFYRDRRPESYETIPAR---------
Mvan_1224|M.vanbaalenii_PYR-1 VDIDETFRTMRAGMFHLRDRRPDVYGPITEVGAGSDLAHA
:*: * ::