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VLEAAGPAAGRLSNDDLAPTTAAQATWRTWDIFCLWMTSAHSLGSYGFAVGMLALGLTGWQTMLALFTGV LVLWTGSNLIGIAGQRLGVPFPVFARATFGVFGANIPALLRGLVAIFWYGIQTYLASTAVIVLLLRLDPG LRSWTEPTFLGLHALGWAAFLSLWTVQLLILNYGMEVVRKASDVAGPVVWIGMLALAVWMLDSVGWSIDF GARTGAPLSAGATVLAFVGVAFLMVAFMAGPLVNYADFARFAPSRRAILRGNALGIPFNETAFVVISIVI SLAALKKYGSAMTDPVELVADIDSDAVVVVAAVLFAIATVGINVVLNFVSPSYDISNVAPKYISFRTGGI ITAVLSVAVLPWKIWGNEAAIVYFLGGVGALMGPVFGILVVDYYLLRRQHTHTADLYSESPGGAYHYAGG FNPAALISLGIGGIVAVVIALVPRAQGVTALSWPVGALLGGVLMYLLGRGRSRSSRVGPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2815c | - | - | 100% (481) | NCS1 nucleoside transporter family protein |
| M. abscessus ATCC 19977 | MAB_2936 | - | e-104 | 41.20% (466) | putative cytosine/purine/uracil/thiamine/ allantoin permease |
| M. abscessus ATCC 19977 | MAB_3432c | - | 5e-07 | 21.17% (359) | cytosine permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3483 | - | 2e-05 | 24.77% (218) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_3170 | - | 1e-109 | 42.39% (460) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1212 | - | 1e-108 | 41.88% (468) | hypothetical protein MMAR_1212 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5730 | - | 1e-103 | 39.30% (486) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2680 | - | 1e-104 | 41.94% (434) | hypothetical protein MUL_2680 |
| M. vanbaalenii PYR-1 | Mvan_0932 | - | 1e-105 | 39.84% (487) | permease for cytosine/purines, uracil, thiamine, allantoin |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1212|M.marinum_M ---------MIDTTAP-----------------HSPVHSPSHGAGPAN--
MUL_2680|M.ulcerans_Agy99 ---------MIDTTAP-----------------HSPVHSPSHGAGPAN--
MSMEG_5730|M.smegmatis_MC2_155 ---------MTETAVPNAGGGPAGPDGSFPVAAGDLVEAAGHPIGSGA--
Mvan_0932|M.vanbaalenii_PYR-1 ---------MTDTAP--APPSRKLPPG-AVVGADDLVEAAGHPVGAGR--
Mflv_3170|M.gilvum_PYR-GCK MSVCALLSKLVEYYFRKVEFSGDARVGAPTVTGVSMSTESTGLIGDSSRN
MAB_2815c|M.abscessus_ATCC_199 -----------------------------------MVLEAAGPA------
Mb3483|M.bovis_AF2122/97 -----MPGVITNSESPTAADHDRITATRETLEDYTLRLAPRSYRRWPPAV
.
MMAR_1212|M.marinum_M ---IKPDYHPRLTNDDLAPLREQ--TWGTYN-----------IFAFWMSD
MUL_2680|M.ulcerans_Agy99 ---IKPDYHPRLTNDDLAPLREQ--TWGTYN-----------IFAFWMSD
MSMEG_5730|M.smegmatis_MC2_155 ---IKPGYDPRLTNEDLAPLRQQ--KWGSYN-----------IFAFWMSD
Mvan_0932|M.vanbaalenii_PYR-1 ---IEPGYDPRLTNEDLAPLRKQ--TWTSYN-----------IFAFWMSD
Mflv_3170|M.gilvum_PYR-GCK DHTALAGVSPHLYNPDLAPTKRAGRRWGSYN-----------IFTLWAND
MAB_2815c|M.abscessus_ATCC_199 --------AGRLSNDDLAPTTAAQATWRTWD-----------IFCLWMTS
Mb3483|M.bovis_AF2122/97 VG--ISALGGIAYLADFAIGANVGITWGTANALCGIAIFALVVFVTGLPL
*:* * : : :*
MMAR_1212|M.marinum_M VHSVGGYVTAGSLFALG-----LASWQVLVSLVIAITIVYFLCNLVARPS
MUL_2680|M.ulcerans_Agy99 VHSVGGYVTAGSLFALG-----LASWQVLVSLVIAITIVYFLCNLVARPS
MSMEG_5730|M.smegmatis_MC2_155 VHSVGGYVTAGSLFALG-----LASWQVLVALLIGISIVNVFCNLVAKPS
Mvan_0932|M.vanbaalenii_PYR-1 VHSVGGYVTAGSLFALG-----LASWQVLVALLAGITIVYYLCNLVAKPS
Mflv_3170|M.gilvum_PYR-GCK VHSLGNYSFAIGLFALG-----LGGWQILLALGLGGVFLFLLLNLSGFMG
MAB_2815c|M.abscessus_ATCC_199 AHSLGSYGFAVGMLALG-----LTGWQTMLALFTGVLVLWTGSNLIGIAG
Mb3483|M.bovis_AF2122/97 AYYAARYNIDLDLITRGSGFGYYGSVVTNVIFATFTFIFFALEGSIMAQG
.: . * .::: * . : : .. . .
MMAR_1212|M.marinum_M QATGVPYPVICRTAFGVLGANIPAIIRGLIAVAWYGIQTYLASAALDVVM
MUL_2680|M.ulcerans_Agy99 QATGVPYPVICRTAFGVLGANIPAIIRGLIAVAWYGIQTYLASAALDVVM
MSMEG_5730|M.smegmatis_MC2_155 QQTGVPYPVICRTVFGVLGANIPAIIRGLIAVAWYGIQTFLASAALDIVL
Mvan_0932|M.vanbaalenii_PYR-1 QATGVPYPVICRTVFGVLGANIPAIIRGLIAVAWYGIQTFLASAALDIVL
Mflv_3170|M.gilvum_PYR-GCK EKTGVPFPVMSRIAFGIRGAQIPALIRGAVAIAWFGIQTYLASVVLRIMI
MAB_2815c|M.abscessus_ATCC_199 QRLGVPFPVFARATFGVFGANIPALLRGLVAIFWYGIQTYLASTAVIVLL
Mb3483|M.bovis_AF2122/97 LKLGLHIPLWAGYACSTL-IIFPLVVYGMKVLSQLQLWTTPLWLILMAAP
*: *: . . . :* :: * .: : * :
MMAR_1212|M.marinum_M IKLFPGLARYAVVEDYGFLGLPALGWASYLILWVLQACVFWRGMEAIRKF
MUL_2680|M.ulcerans_Agy99 IKLFPGLARYAVVEDYGFLGLPALGWASYLILWVLQACVFWRGMEAIRKF
MSMEG_5730|M.smegmatis_MC2_155 VKLFPALAPYAVVDDYGFAGLSLLGWGSFLLLWVLQACVFWRGMESIRKF
Mvan_0932|M.vanbaalenii_PYR-1 IKLFPALAPYAVVEDFGFAGLSLLGWCSFLLLWVLQACVFWRGMESIRKF
Mflv_3170|M.gilvum_PYR-GCK IALAPSAES---LDSNSVLGLSTLGWISFVVLWVVRVIIVSYGMEMIRRY
MAB_2815c|M.abscessus_ATCC_199 LRLDPGLRS---WTEPTFLGLHALGWAAFLSLWTVQLLILNYGMEVVRKA
Mb3483|M.bovis_AF2122/97 FGYLVVSHPDSIGQFFSYAGKDGHGGLSFGSVLLAAGVCLSLIAQIAEQI
. * * :: : . : .:
MMAR_1212|M.marinum_M IDFCGPAVYVVMFALSGYLISKAGWAAIDLNLGDVRYSGWDAIPVMLGAI
MUL_2680|M.ulcerans_Agy99 IDFCGPAVYVVIFALSGYLISTAGWAAIDLNLGDVRYSGWDAIPVMLGAI
MSMEG_5730|M.smegmatis_MC2_155 IDFCGPAVYVVMFLLCGYLIFQAGWGAIDLSLGEVTYTGWSSVPVMLGAI
Mvan_0932|M.vanbaalenii_PYR-1 IDFCGPAVYVVMFLLCGYLISEAGWGAIDLNLGDVTYTGWSSVPVMLGAI
Mflv_3170|M.gilvum_PYR-GCK EAFAGPVILVTMIALAVWMLNNADWS-IAWSTPDS-LTGVDMWLKIIGGA
MAB_2815c|M.abscessus_ATCC_199 SDVAGPVVWIGMLALAVWMLDSVGWSIDFGARTGAPLSAGATVLAFVGVA
Mb3483|M.bovis_AF2122/97 DYLRFMPPRTPENANRWWTWTLLAGPGWVAFGATKQIIGLFLAVYLMANI
. : . ::.
MMAR_1212|M.marinum_M ALVVSYFSGPMLNFGDFSR-YGRSFGAVRKGNFLGLPLNFLLFSLLVVVT
MUL_2680|M.ulcerans_Agy99 ALVVSYFSGPMLNFGDFSR-YGRSFGAVRKGNFLGLPLNFLLFSLLVVVT
MSMEG_5730|M.smegmatis_MC2_155 ALVVSYFSGPMLNFGDFSR-YGRTFAAVKKGNFLGLPVNFLVFSVLVVVT
Mvan_0932|M.vanbaalenii_PYR-1 ALVVSYFSGPMLNFGDFSR-YGKSFEAVKKGNFLGLPVNFLLFSVLVVVT
Mflv_3170|M.gilvum_PYR-GCK SLWVAIYGTFVLNFCDFTR-NATSKRAIVHGNFWGIPLNMLVFGGIVITL
MAB_2815c|M.abscessus_ATCC_199 FLMVAFMAGPLVNYADFAR-FAPSRRAILRGNALGIPFNETAFVVISIVI
Mb3483|M.bovis_AF2122/97 PGSSTIANQPVHQFMQIYRTFVPGWLALTLAVILVILSQIKINVTNAYSG
: : :: :: * *: . : :
MMAR_1212|M.marinum_M ASLTVPVFGELITDPVQTVARIDSTFAIILGASTFTIATIGINIVANFIS
MUL_2680|M.ulcerans_Agy99 ASLTVPVFGELITDPVQTVARIDSTFAIILGASTFTIATIGINIVANFIS
MSMEG_5730|M.smegmatis_MC2_155 ASLTLPVFGELITDPVETVARIDSTFAIVLGALTFAIATIGINIVANFIS
Mvan_0932|M.vanbaalenii_PYR-1 ASLTLPVFGELITDPVETVARIDSTFAIVLGALTFATATIGINIVANFIS
Mflv_3170|M.gilvum_PYR-GCK AGAQFRIDGRIIEAPADIVQEVPNTFLLVLAALALLILTIAVNLMANFVA
MAB_2815c|M.abscessus_ATCC_199 SLAALKKYGSAMTDPVELVADIDSDAVVVVAAVLFAIATVGINVVLNFVS
Mb3483|M.bovis_AF2122/97 SLAWTNSFTRLTKHYPGRVVFLGVNLAIALILMEANMFDFLNTILGCYAN
: * : : : . .:: :
MMAR_1212|M.marinum_M PAFDFSNVNPQRISWRTGGMIAAVGSALITPWNLYNH-PDVIHYTLETLG
MUL_2680|M.ulcerans_Agy99 PAFDFSNVNPQRIGWRTGGMIAAVGSALITPWNLYNH-PDVIHYTLETLG
MSMEG_5730|M.smegmatis_MC2_155 PAFDFSNVSPQRISWRAGGMIAAVGSVLITPWNLYNN-PEVIHYTLETLG
Mvan_0932|M.vanbaalenii_PYR-1 PAFDFSNVSPQRISWRAGGMIAAVGSVLITPWNLYNN-PEVIHYTLETLG
Mflv_3170|M.gilvum_PYR-GCK PIYALNNLFPKHLNFRRAAFISAVIGLVILPWNLYNT-PAVINYFLGGLG
MAB_2815c|M.abscessus_ATCC_199 PSYDISNVAPKYISFRTGGIITAVLSVAVLPWKIWGN-EAAIVYFLGGVG
Mb3483|M.bovis_AF2122/97 CGMAWVVAVASDIGFNKYLLGLSPKTPEFRRGMLYAINPVGFGSLLLAAG
.. :.:. : : . :: : * *
MMAR_1212|M.marinum_M AFIGPLFG-----VLIADYYLVRKQHVVVDDLFSLSHDGTYWYRKGYNPA
MUL_2680|M.ulcerans_Agy99 AFIGPLFG-----VLIADYYLVRKQHVVVDDLFSLSHDGTYWYRKGYNPA
MSMEG_5730|M.smegmatis_MC2_155 AFIGPLFG-----VLIADFYLVRKQKVIVDDMFTLDESGKYWYTKGYNKV
Mvan_0932|M.vanbaalenii_PYR-1 AFIGPLFG-----VLIADYYLVRKQQVVVDDLFTMEESGKYWYTKGYNRV
Mflv_3170|M.gilvum_PYR-GCK AILGPLFG-----IIMADYWLVRRSKINVLALFTTDADGEYHYAKGVNVR
MAB_2815c|M.abscessus_ATCC_199 ALMGPVFG-----ILVVDYYLLRRQHTHTADLYSESPGGAYHYAGGFNPA
Mb3483|M.bovis_AF2122/97 LSIVTFFGGLGAALQPYSPLVAIVTALVMPPILAAATKGKYYLRRTHDGI
: ..** : . : : : * * :
MMAR_1212|M.marinum_M AVIATAVSAAIAMVPVLAS-DVYGMYTAAEYSWFIGCGVALVVYYLLATR
MUL_2680|M.ulcerans_Agy99 AVIATAVSAAIAMAPVLAS-DV----------------------------
MSMEG_5730|M.smegmatis_MC2_155 AVIATVVGAVLAVIPVLLGGSVAGMHTAAQYSWFIGCGIAFGLYYVLAKR
Mvan_0932|M.vanbaalenii_PYR-1 AVLATAVGAVLAVVPVLLGGSVAGMATAAQYSWFIGCGVAFAIYYLVAKR
Mflv_3170|M.gilvum_PYR-GCK AVIALVITAVAALLLAFVP----AFAVVAEFSWFIGAGLGAIVYLVVADR
MAB_2815c|M.abscessus_ATCC_199 ALISLGIGGIVAVVIALVP----RAQGVTALSWPVGALLGGVLMYLLGRG
Mb3483|M.bovis_AF2122/97 DLPMYDEHGNPSAAVLTCHVCHQDFERPDMLACQTHGAHVCSLCLSTDKQ
: . :
MMAR_1212|M.marinum_M GRLAIAPPYHPVGAG----
MUL_2680|M.ulcerans_Agy99 -------------------
MSMEG_5730|M.smegmatis_MC2_155 DTLVAASVS----------
Mvan_0932|M.vanbaalenii_PYR-1 DTLVAASLS----------
Mflv_3170|M.gilvum_PYR-GCK RGPFNDVSGEPIAVDSTH-
MAB_2815c|M.abscessus_ATCC_199 RSRSSRVGPA---------
Mb3483|M.bovis_AF2122/97 AEHVLPGLARAHIPGDQVP