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AHDSANEMSVDARTLLADIVSDGQLQRVVDIAERAANLIAGFSEKPGGMPLSEVLDWIERINADAVASLR EDRPPDLALARRLGARCCEAQVALADAQTLRRMVFDSDWRHLFVSLRSRSISVEIAVDITAAHWELMNEI DDAIVEAYREVETSRKMRRAERNAVLVDVLLADAMPDPDTTFARLNELMIASAPFYCVTVIRVAKLGEAP LPNIENLLRRESFDSAWRLGAEAQTGIVAVQSRSGAIRLKETLVRLKAAGTGISVPVSALEIPKGLRLAQ LASETTTEREQVIVFGDNVTDTTIVAASPEVLRLLSSQSFREVLRLPDATREHLLETFERWLECKGSVRL TALALDRHVNTVRQRLNKIQELTGKSLDNPRDLADLVVLIRFARSDLSSTGEN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2653c | - | - | 100% (404) | hypothetical protein MAB_2653c |
| M. abscessus ATCC 19977 | MAB_0762 | - | 1e-31 | 29.19% (322) | hypothetical protein MAB_0762 |
| M. abscessus ATCC 19977 | MAB_1880c | - | 8e-06 | 27.54% (138) | hypothetical protein MAB_1880c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2266 | - | 8e-07 | 32.09% (134) | hypothetical protein Mb2266 |
| M. gilvum PYR-GCK | Mflv_0801 | - | 4e-08 | 29.67% (182) | transcriptional regulator, CdaR |
| M. tuberculosis H37Rv | Rv2242 | - | 8e-07 | 32.09% (134) | hypothetical protein Rv2242 |
| M. leprae Br4923 | MLBr_01652 | - | 1e-05 | 42.86% (49) | hypothetical protein MLBr_01652 |
| M. marinum M | MMAR_3335 | - | 9e-07 | 30.50% (141) | hypothetical protein MMAR_3335 |
| M. avium 104 | MAV_4933 | - | 5e-05 | 41.33% (75) | hypothetical protein MAV_4933 |
| M. smegmatis MC2 155 | MSMEG_6492 | - | 4e-05 | 34.72% (72) | GAF domain-containing protein |
| M. thermoresistible (build 8) | TH_1338 | - | 1e-05 | 34.41% (93) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1307 | - | 5e-07 | 30.50% (141) | hypothetical protein MUL_1307 |
| M. vanbaalenii PYR-1 | Mvan_0042 | - | 3e-07 | 29.67% (182) | purine catabolism PurC domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3335|M.marinum_M --------------------------------------------------
MUL_1307|M.ulcerans_Agy99 --------------------------------------------------
Mb2266|M.bovis_AF2122/97 --------------------------------------------------
Rv2242|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01652|M.leprae_Br4923 --------------------------------------------------
TH_1338|M.thermoresistible__bu --------------------------------------------------
Mflv_0801|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0042|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4933|M.avium_104 --------------------------------------------------
MSMEG_6492|M.smegmatis_MC2_155 MTWLGALRRLSASATAEEDLSHVLAEIAETARSLLGFDFCGVLLPDEQSR
MAB_2653c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3335|M.marinum_M ---------------------------------MNDNQFSAIARLG-SAR
MUL_1307|M.ulcerans_Agy99 ---------------------------------MNNNQFSAIARLG-SAR
Mb2266|M.bovis_AF2122/97 ---------------------------------MNDNQLAPVARP----R
Rv2242|M.tuberculosis_H37Rv ---------------------------------MNDNQLAPVARP----R
MLBr_01652|M.leprae_Br4923 ---------------------------------MNHNHFVPAPPR----R
TH_1338|M.thermoresistible__bu ---------------------------------VPDNRFVPPQST-----
Mflv_0801|M.gilvum_PYR-GCK ---------------------------------MSEDRAESAAPTLRDLL
Mvan_0042|M.vanbaalenii_PYR-1 ---------------------------------MSEVHAEPAAPTLRDLA
MAV_4933|M.avium_104 ---------------------------------MKDFRAPVNGVDG--DS
MSMEG_6492|M.smegmatis_MC2_155 HLRVRGASGLSSDYVDRVNSDRPLVLHGGSPSSRAFHTAEAVAIRDVTAE
MAB_2653c|M.abscessus_ATCC_199 ---------------------------------MAHDSANEMSVD-----
MMAR_3335|M.marinum_M SPLELLETVPDSLLRRLKQYSGRLATEAVSAMQERLP-------------
MUL_1307|M.ulcerans_Agy99 SPLELLETVPDSLLRRLKQYSGRLATEAVSAMQERLP-------------
Mb2266|M.bovis_AF2122/97 SPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLP-------------
Rv2242|M.tuberculosis_H37Rv SPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLP-------------
MLBr_01652|M.leprae_Br4923 LPLELLDTVPDSLLRRLKQYSGRLATEAVTAMQERLP-------------
TH_1338|M.thermoresistible__bu --LEVLESVPESVLRRLKQYSGRLATEAVHTMEERLP-------------
Mflv_0801|M.gilvum_PYR-GCK EAAQLSLSGPDPADRNLDREVSWVHTTEMRDPSRYLRGGELVCTVGISLH
Mvan_0042|M.vanbaalenii_PYR-1 TAG-LGLSVPDGTAQELDRPVSWVHTTEMRDPSRYLRGGELVCTVGISLH
MAV_4933|M.avium_104 ASALVAVPKSQGAQTIRPDSVSRLVGALLDDHAAVVG-------------
MSMEG_6492|M.smegmatis_MC2_155 PGFELWAGIANEQGYRSMIAVPLVARGEVLGTLNGYYGAVHTYTRFEVER
MAB_2653c|M.abscessus_ATCC_199 -ARTLLADIVSDGQLQRVVDIAERAANLIAGFSEKPG-------------
: . :
MMAR_3335|M.marinum_M -------FFADLEASQRASVALVVQTAVVNFAEWMQNPR------SDVSY
MUL_1307|M.ulcerans_Agy99 -------FFADLEASQRASVALVVQTAVVNFAEWMQNPR------SDVSY
Mb2266|M.bovis_AF2122/97 -------FFADLEASQRASVALVVQTAVVNFVEWMHDPH------SDVGY
Rv2242|M.tuberculosis_H37Rv -------FFADLEASQRASVALVVQTAVVNFVEWMHDPH------SDVGY
MLBr_01652|M.leprae_Br4923 -------FFADLEASQRASVTLVVQTAVVNFVQWMQNPH------SDVSY
TH_1338|M.thermoresistible__bu -------FFADLEASQRASVHLVVQTAVVNFVEWMRDPR------SNVTY
Mflv_0801|M.gilvum_PYR-GCK SAEDCSTFVDALAGAGAAGVCFGVGDGHDDVPAALLDACRRAGLPVLVAP
Mvan_0042|M.vanbaalenii_PYR-1 TDQDCATFVDALSRARAAGVCFGVGDEHDAVPEALLAQCRLHGLPLLVAP
MAV_4933|M.avium_104 -------RVRSVIRSRLPVYRSVADEALEAELEWVLRSAVG----GREAL
MSMEG_6492|M.smegmatis_MC2_155 MTLLANHAAIAVSSARRLDELRALTASLRRQRDALTRSEQIHDRLLAVTL
MAB_2653c|M.abscessus_ATCC_199 ----------GMPLSEVLDWIERINADAVASLREDRPPD---------LA
: :
MMAR_3335|M.marinum_M TAQAFELVPQDLTRRIALRHTVDMVRVTMEFFEEVVPLLARSEEQLTALT
MUL_1307|M.ulcerans_Agy99 TAQAFELVPQDLTRRIALRHTVDMVRVTMEFFEEVVPLLARSEEQLTALT
Mb2266|M.bovis_AF2122/97 TAQAFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALT
Rv2242|M.tuberculosis_H37Rv TAQAFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALT
MLBr_01652|M.leprae_Br4923 TAQAFELVPQDLARRIALRHTVDMVRVTMEFFEEVVPLLARSEEQLTALT
TH_1338|M.thermoresistible__bu TMQAFEVVPQDLTRRIALRQTVEMVRTTMEFFEQVVPLLARSEEQVTALT
Mflv_0801|M.gilvum_PYR-GCK PSVPFSVISR-FVAESRLGTEIAVARATNALVPELLLSLRRHDSPRRLLD
Mvan_0042|M.vanbaalenii_PYR-1 PSVPFSVVSR-FVAEYWLGSEIAVARATNALVPELLSSLRRHDSPRQLLD
MAV_4933|M.avium_104 HEPQIAGLAAIGEARARDGVPVDDMLRAWRIGVEVVVECAREAARRLGVD
MSMEG_6492|M.smegmatis_MC2_155 RSGGLDGIAAVLQGLIGRPILIDDIQHEVLACSVVTTDFPDTTWRAAAEA
MAB_2653c|M.abscessus_ATCC_199 LARRLGARCCEAQVALADAQTLRRMVFDSDWRHLFVSLRSRSISVEIAVD
: : .
MMAR_3335|M.marinum_M VG---------------------------------ILKYSRDLAFTAASA
MUL_1307|M.ulcerans_Agy99 VG---------------------------------ILKYSRDLAFTAASA
Mb2266|M.bovis_AF2122/97 VG---------------------------------ILKYSRDLAFTAATA
Rv2242|M.tuberculosis_H37Rv VG---------------------------------ILKYSRDLAFTAATA
MLBr_01652|M.leprae_Br4923 VG---------------------------------ILKYSRDLAFTAATA
TH_1338|M.thermoresistible__bu AG---------------------------------ILRYSRDLAFAAATA
Mflv_0801|M.gilvum_PYR-GCK AAGQVLGCY--------------------------FLLEPEGAAKGDEAA
Mvan_0042|M.vanbaalenii_PYR-1 SAGQLLGCY--------------------------FLLEPEGGADSDDDA
MAV_4933|M.avium_104 DAR--------------------------------VLELVQSALAWSDIA
MSMEG_6492|M.smegmatis_MC2_155 GTGSSPVPVGQFDGTTYLASAVHLGDEVAARIWFPETSIDLDPIMVRAVE
MAB_2653c|M.abscessus_ATCC_199 IT-----------------------------------AAHWELMNEIDDA
MMAR_3335|M.marinum_M YADAAEARG--TWDSRMEAS------VVDAVVRG--DTGPELLSRAAALN
MUL_1307|M.ulcerans_Agy99 YADAAEARG--TWDSRMEAS------VVDAVVRG--DTGPELLSRAAALN
Mb2266|M.bovis_AF2122/97 YADAAEARG--TWDSRMEAS------VVDAVVRG--DTGPELLSRAAALN
Rv2242|M.tuberculosis_H37Rv YADAAEARG--TWDSRMEAS------VVDAVVRG--DTGPELLSRAAALN
MLBr_01652|M.leprae_Br4923 YADAAEARG--TWDSRMEAS------VVDAVVRG--DTGPELLSRAAALN
TH_1338|M.thermoresistible__bu YADAAEARG--AWDTRMEAN------VVDAVVRG--AVGPELQSQAAALN
Mflv_0801|M.gilvum_PYR-GCK VTVPVPGLGALVWMGRGDRPEPALLDLIARFVRA--AQGERDIEAALTRE
Mvan_0042|M.vanbaalenii_PYR-1 VTVPVPGLGTLVWVGRGDHPEPALLDLIARFVRA--AQGERDIEAALARE
MAV_4933|M.avium_104 MATSAKAHRRTERALALEAEE-----SDAEFVRG--ALMGSLPAAELRMH
MSMEG_6492|M.smegmatis_MC2_155 HASIVTALELLRCQTAAEVEQRLRGELLSDVLSSGAALSDRLLDRAHRLG
MAB_2653c|M.abscessus_ATCC_199 IVEAYREVETSRKMRRAERN-----AVLVDVLLADAMPDPDTTFARLNEL
. : .: .
MMAR_3335|M.marinum_M WDTTAPATVVVGTP----ASARDGS--DG-SERAIQDVRDAAAQHGRAAL
MUL_1307|M.ulcerans_Agy99 WDTTAPATVVVGTP----ASARDGS--DG-SERAIQDVRDAAAQHGRAAL
Mb2266|M.bovis_AF2122/97 WDTTAPATVLVGTP----APGPNGSNSDGDSERASQDVRDTAARHGRAAL
Rv2242|M.tuberculosis_H37Rv WDTTAPATVLVGTP----APGPNGSNSDGDSERASQDVRDTAARHGRAAL
MLBr_01652|M.leprae_Br4923 WDTTAPATVVVGTP----TPNHDGPNGQVSSERASQEVREIAARHGRAAL
TH_1338|M.thermoresistible__bu WDATAPATVVVGLP----RPD--------RLEVVSQDVHHVANRHGRTAL
Mflv_0801|M.gilvum_PYR-GCK RVGQLLSLVERRML----LPDALSQ-LVQWPGF-AGEIACSAWPAGAGAL
Mvan_0042|M.vanbaalenii_PYR-1 RVGQLLSLVERRML----LPDALSQ-LLEWPGFSAGEIACSAWPAGAGAL
MAV_4933|M.avium_104 AELRGLDPGAEYVA----VRARLGG--DGPHLRLEQSLGFQDPAHSRRGL
MSMEG_6492|M.smegmatis_MC2_155 HDLTVPHIAIVGAFTGLDPVAERRAYERSLVLLAKESAAHRPKPVVAMHA
MAB_2653c|M.abscessus_ATCC_199 MIASAPFYCVTVIR----VAKLGEAPLPNIENLLRRESFDSAWRLGAEAQ
.
MMAR_3335|M.marinum_M TDVHGTWLVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAAYHS
MUL_1307|M.ulcerans_Agy99 TDVHGTWLVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAAYHS
Mb2266|M.bovis_AF2122/97 TDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRS
Rv2242|M.tuberculosis_H37Rv TDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRS
MLBr_01652|M.leprae_Br4923 TDVHGTWLVAIISGQLAPTDKFFSDLLHAFSDGPVVIGPTAPMLTAAYHS
TH_1338|M.thermoresistible__bu SDVHGTWLVTIVSGALSPTDRFLTDLLDVFADGPVVLGPTAPTLSAAYRS
Mflv_0801|M.gilvum_PYR-GCK LSIS--FPGALIGDAPDLCMMLTAGAVEMPDDLALPTGHSAPVTLADLGS
Mvan_0042|M.vanbaalenii_PYR-1 VSMA--FPDALIGDAPDLCLMLTVGALEVTDDLALPTGHSAPVPLTDIGS
MAV_4933|M.avium_104 CALLDGDLAG--------------FLIEPPRDVEGVVGFGPPRPLTRLSE
MSMEG_6492|M.smegmatis_MC2_155 GTIVMLWPAQDAADAAGAGEVVRQAMRAASADRQATVAVG-PGDVASHRE
MAB_2653c|M.abscessus_ATCC_199 TGIVAVQSRS---GAIRLKETLVRLKAAGTGISVPVSALEIPKGLRLAQL
: . *
MMAR_3335|M.marinum_M ASEAISGMNAVAGWRG------APRPVLARELLPERALMGDASAIVALHT
MUL_1307|M.ulcerans_Agy99 ASEAISGMNAVAGWRG------ASRPVLARELLPERALMGDASAIVALHT
Mb2266|M.bovis_AF2122/97 ASEAISGMNAVAGWRG------APRPVLARELLPERALMGDASAIVALHT
Rv2242|M.tuberculosis_H37Rv ASEAISGMNAVAGWRG------APRPVLARELLPERALMGDASAIVALHT
MLBr_01652|M.leprae_Br4923 ASEAVSGMNAVAGWSG------APRPVQARELLPERALMGDASAIVALHT
TH_1338|M.thermoresistible__bu ATEAIAGMNAVAGWSG------APRPVPARELLPERALLGDQTAIAALES
Mflv_0801|M.gilvum_PYR-GCK AIAQARIALTLAEHRGG---RVGPDQLSTLESLLEQLPLAQLAPFRQLLI
Mvan_0042|M.vanbaalenii_PYR-1 AIAQARIALTLAEHRGG---RVGPDQLSTLESLLEQLPLAQLAPFKQLLI
MAV_4933|M.avium_104 SYRMAARALVTAEACG----LRGAYDIAALGLRTAVAIDADVGELLRKRY
MSMEG_6492|M.smegmatis_MC2_155 SYQTAKGALQVAIMSGRTAAVVGLDDLGIAGLLLRINDPAALSTFARRTL
MAB_2653c|M.abscessus_ATCC_199 ASETTTEREQVIVFGDN-----------VTDTTIVAASPEVLRLLSSQSF
: . :
MMAR_3335|M.marinum_M DVMRPLAD-AGPTLIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRIT
MUL_1307|M.ulcerans_Agy99 DVMRPLAD-AGPTLIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRIT
Mb2266|M.bovis_AF2122/97 DVMRPLAD-AGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRIT
Rv2242|M.tuberculosis_H37Rv DVMRPLAD-AGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRIT
MLBr_01652|M.leprae_Br4923 DVMLPLAD-AGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRIT
TH_1338|M.thermoresistible__bu EVMRPLAD-AGPTLTETLDAFLESGGAIEACARRLFVHPNTVRYRLRRIA
Mflv_0801|M.gilvum_PYR-GCK DPLTELDTSRGTQHVRTLRTFVACNGSLSETAKELFLHTNTVRHRLGRIQ
Mvan_0042|M.vanbaalenii_PYR-1 APLAELDSQRGTQHVRTLRVFLACNGSLSETAKELFLHTNTVRHRLSRIQ
MAV_4933|M.avium_104 LEPLSVGG-SSRELIATVRTYLACGMHVERTATRLFVHQNTVRYRLARFE
MSMEG_6492|M.smegmatis_MC2_155 APILDYDHAHRTELLVTLRAYLECRQERSATATRLVIHPNTVAQRLRRIE
MAB_2653c|M.abscessus_ATCC_199 REVLRLPDATREHLLETFERWLECKGSVRLTALALDRHVNTVRQRLNKIQ
*. :: . * * * **: ** ::
MMAR_3335|M.marinum_M DFTGRDPTQPRDAYVLRVAATVGQLNYPTPPSGAANNTITPVPLPVRRGT
MUL_1307|M.ulcerans_Agy99 DFTGRDPTQPRDAYVLRVAATVGQLNYPTPPSGAANNTITPVPLPVRRGT
Mb2266|M.bovis_AF2122/97 DFTGRDPTQPRDAYVLRVAATVGQLNYPTPH-------------------
Rv2242|M.tuberculosis_H37Rv DFTGRDPTQPRDAYVLRVAATVGQLNYPTPH-------------------
MLBr_01652|M.leprae_Br4923 DFTGHDPTLPRDAYVLRVAATVGKLNYPTHH-------------------
TH_1338|M.thermoresistible__bu EITGRDPAVPRDAYVLRVAVSVSRLTRQSYQSSTVNPDLGSTAGWRGQAA
Mflv_0801|M.gilvum_PYR-GCK EITGRDPLQHNDLTTFVIGMWAADRGE-----------------------
Mvan_0042|M.vanbaalenii_PYR-1 EITGRDPLQHNDLTAFVIGLWAADRAERPAGL------------------
MAV_4933|M.avium_104 ELTG---ASLRDTEVVTEVWWVLELAAMRL--------------------
MSMEG_6492|M.smegmatis_MC2_155 SLCSVTLTDPAVILQFSAALTVYDIAALD---------------------
MAB_2653c|M.abscessus_ATCC_199 ELTGKSLDNPRDLADLVVLIRFARSDLSSTGEN-----------------
.: . .
MMAR_3335|M.marinum_M EGP---
MUL_1307|M.ulcerans_Agy99 EGP---
Mb2266|M.bovis_AF2122/97 ------
Rv2242|M.tuberculosis_H37Rv ------
MLBr_01652|M.leprae_Br4923 ------
TH_1338|M.thermoresistible__bu GGHRAM
Mflv_0801|M.gilvum_PYR-GCK ------
Mvan_0042|M.vanbaalenii_PYR-1 ------
MAV_4933|M.avium_104 ------
MSMEG_6492|M.smegmatis_MC2_155 ------
MAB_2653c|M.abscessus_ATCC_199 ------