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SLGQVFDPRRNALTSWRLVLAIGVVFWHSWPLTGREIGYAPAARLLGDIFADGFFVISGFLITAAWVRRP NLKEYWASRALRIFPGLWICLMVIAFVIAPIAARVKHTSITFSSELGYVVNNALLNVAYLDIDETPADVP YPGVWDGSIWTLFFVLLCDVMVSVLGVAGLLKRHWVIPILLISALFCSAHFSYTPESYTWPQMLSRFFVV FLAGALFYQYQDKIPAHWSLVVLSVGLVVASGFTQNYRVLGALPLAYAVIVSGALIRKTRLRNDFSYGVY IYAFPIQQLLATFGLARLNPFLFFLLAATATLPIAALSWFVVEKRAMALKARIFRRSNRKPAAQRATVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2552c | - | - | 100% (350) | putative acetyltransferase |
| M. abscessus ATCC 19977 | MAB_4106c | - | e-115 | 57.42% (357) | acetyltransferase |
| M. abscessus ATCC 19977 | MAB_1725c | - | e-110 | 57.06% (333) | putative acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0530 | - | 1e-06 | 26.61% (233) | membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_0420 | - | 5e-05 | 35.78% (109) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0517 | - | 1e-06 | 26.61% (233) | membrane acyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4188 | - | 1e-06 | 27.73% (256) | integral membrane acyltransferase |
| M. avium 104 | MAV_3274 | - | 1e-104 | 56.10% (344) | putative acyltransferase |
| M. smegmatis MC2 155 | MSMEG_3429 | - | 1e-148 | 72.00% (350) | O-acyl transferase |
| M. thermoresistible (build 8) | TH_2230 | - | 1e-06 | 25.30% (249) | PROBABLE ACYLTRANSFERASE |
| M. ulcerans Agy99 | MUL_4492 | - | 1e-06 | 27.34% (256) | integral membrane acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4285 | - | 2e-06 | 27.84% (194) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4188|M.marinum_M ----MTLP----------EATDAQGGLEQISHVDRVASLTGIRAVAALLV
MUL_4492|M.ulcerans_Agy99 ----MTLP----------EATDAQGGLEQISHVDRVASLTGIRAVAALLV
TH_2230|M.thermoresistible__bu ----MTVRRGGEL----TEPDVVQGGLESISRAERVASLTGIRAVAALLV
Mvan_4285|M.vanbaalenii_PYR-1 ----MSASLG-------VRCGAAPAGPPDHT-SPRDPALTGLRAVAALLV
Mflv_0420|M.gilvum_PYR-GCK ----MSATGTAS-----SRGDVGASGDGVGGTRSFLPAVEGLRAWAAIGV
Mb0530|M.bovis_AF2122/97 MAGGMDQPPGQPRRRTRQQSSDGKNGVRAAEITGEIRALTGLRIVAAVWV
Rv0517|M.tuberculosis_H37Rv MAGGMDQPPGQPRRRTRQQSSDGKNGVRAAEITGEIRALTGLRIVAAVWV
MAB_2552c|M.abscessus_ATCC_199 -------------------------MSLGQVFDPRRNALTSWRLVLAIGV
MSMEG_3429|M.smegmatis_MC2_155 ------------------------MMSLADVFDRRRNALTLWRLFLAIGV
MAV_3274|M.avium_104 MSADPNVSDPTTIAARGPARRRVPGPTLAQVFDTRINALNVWRLVLASGV
:: * * *
MMAR_4188|M.marinum_M VATHAAYTTGKYTHGYWGLVSARMEIGVP---IFFVLSGFLLFRPWVHSA
MUL_4492|M.ulcerans_Agy99 VTTHAAYTTGKYTHGYWGLVSARMEIGVP---IFFVLSGFLLFRPWVHSA
TH_2230|M.thermoresistible__bu VLTHAAYTTGRYPQGYLGLVYSRMEIGVP---IFFVLSGFLLFGPWVRAA
Mvan_4285|M.vanbaalenii_PYR-1 VSTHAAFATGYLLHGYLGTMYARLEIGVA---VFFVLSGFLLFRPWVRAA
Mflv_0420|M.gilvum_PYR-GCK VITHVAFQTGQ-SGGAVGRILGRFDLAVA---VFFALSGFLLWRGHAAAA
Mb0530|M.bovis_AF2122/97 VLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFVLTWNYLDRM
Rv0517|M.tuberculosis_H37Rv VLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFVLTWNYLDRM
MAB_2552c|M.abscessus_ATCC_199 VFWHSWPLTGREIGYAPAARLLGDIFADG----FFVISGFLITAAWVR--
MSMEG_3429|M.smegmatis_MC2_155 VFWHSWPLTGREIGFVPAVRLLSDMFADG----FFIISGFLITAAWFR--
MAV_3274|M.avium_104 ILQHSWPLTGRKV-HPPYDQLFPQVWVDG----FFAISGFLIAASWVR--
: * * ** :***::
MMAR_4188|M.marinum_M VTGAPPPSLRRYTAHRVRRIMPAYVV-----VVLIAYVIYHYRIAGPNPG
MUL_4492|M.ulcerans_Agy99 VTGAPPPSLRRYTAHRVRRIMPAYVV-----VVLIAYVIYHYRIAGPNPG
TH_2230|M.thermoresistible__bu AERRPAPSVKRYAWRRVRRIMPAYVV-----TVLAAYAVYHFRDAGPNPG
Mvan_4285|M.vanbaalenii_PYR-1 AAGRRAPSARRYGRQRMRRIVPAYVV-----TVVAVFEIYTVFTPGPNPG
Mflv_0420|M.gilvum_PYR-GCK RGLRSRPSTGHYLRSRIVRIMPGYLV-----AVVVILTLLPEAKADVT--
Mb0530|M.bovis_AF2122/97 GRSWSVRANLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHVGHVPSPEAG
Rv0517|M.tuberculosis_H37Rv GRSWSVRANLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHVGHVPSPEAG
MAB_2552c|M.abscessus_ATCC_199 -----RPNLKEYWASRALRIFPGLWICLMVIAFVIAPIAARVKH---TSI
MSMEG_3429|M.smegmatis_MC2_155 -----RPYLKEYWASRGLRIFPGLWVCVVLIAFVAAPIAAKATN---TTI
MAV_3274|M.avium_104 -----NPRLREYVAARALRILPGLWVCLVVIAFVIAPIGVAIQGGSAAKL
.: * *: * : ..
MMAR_4188|M.marinum_M HS---WLGLVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPF
MUL_4492|M.ulcerans_Agy99 HS---WMGLVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPF
TH_2230|M.thermoresistible__bu HT---WEGLLRNLTHTQIYTDNYLYSYLHQGLTQMWSLAVEVAFYAVLPL
Mvan_4285|M.vanbaalenii_PYR-1 QT---WQGLLRYLTFTHIYTDDYLVTLLHPGLSQMWSLAVEASFYVALPA
Mflv_0420|M.gilvum_PYR-GCK -------VWLANLTLTQIYVP----LTLTAGLTQMWSLSVEMSFYLALPL
Mb0530|M.bovis_AF2122/97 QLT--AISYVRQILLVQLWFQPYFDGSSWDGP--AWSISAEWLAYLLFGL
Rv0517|M.tuberculosis_H37Rv QLT--AISYVRQILLVQLWFQPYFDGSSWDGP--AWSISAEWLAYLLFGL
MAB_2552c|M.abscessus_ATCC_199 TFS-SELGYVVNNALLNVAYLDIDETPADVPYPGVWDGSIWTLFFVLLCD
MSMEG_3429|M.smegmatis_MC2_155 TLS-SEIWYVVNNAVLNIAYANIDGTPTDVPYPGIWNGSIWTLFFVLLCD
MAV_3274|M.avium_104 LMSRAPIEYVLHNAVLHVFFAGIDGTPRHVPFPGVWDGVLWTLIFEIFCY
: :: *. : :
MMAR_4188|M.marinum_M LAYLLLVVISRRRWQPKLVVGALLAMATITPGWLVLIHTVSLFPDGARLW
MUL_4492|M.ulcerans_Agy99 LAYLLLVVISRRRWQPKLVVGALLAMATITPGWLVLIHTVSLFPDGARLW
TH_2230|M.thermoresistible__bu LAYLLLVVVCRRRWRPGLLLTGLAVLAAISPAWLYLVHTVDWLPDGARLW
Mvan_4285|M.vanbaalenii_PYR-1 LAFLVLQVLCRGRWRPGRALVGIALLAAVTPVWLVVVTATDLLPNSAGMW
Mflv_0420|M.gilvum_PYR-GCK LALLARRVPVRARIP-------VLIGAAAASLLWVHIPFDGASGHNLWNW
Mb0530|M.bovis_AF2122/97 LILVIFRMKHATRAR------GLMWLAFAASLPPVVLLLASGQFYTPWSW
Rv0517|M.tuberculosis_H37Rv LILVIFRMKHATRAR------GLMWLAFAASLPPVVLLLASGQFYTPWSW
MAB_2552c|M.abscessus_ATCC_199 VMVSVLGVAGLLKRH------WVIPILLISALFCSAHFSYTPESYTWPQM
MSMEG_3429|M.smegmatis_MC2_155 LMVSVLGFVGLLKRR------WTIPTLFVAAVCWCAYVSYTPPGYSMAQM
MAV_3274|M.avium_104 IAIAVAGVAGLLKRR------WPAVVVFILLVVFSALVAYPVEVQTVFQM
: . :
MMAR_4188|M.marinum_M LPSYLAWFLGGMLLTVLQAMKVQCYALAALP------LATICYFIVATPI
MUL_4492|M.ulcerans_Agy99 LPSYLAWFLGGMLLTVLQAMKVQCYALAALP------LATICYFIVATPI
TH_2230|M.thermoresistible__bu LPTYLIWFLGGMMLAALQPMGVRAYALVCIP------LALICYFIVATPI
Mvan_4285|M.vanbaalenii_PYR-1 LPAHLAWFAGGMALAVLEAVGARCAAIVAIP------VAVGLYLAVSTSL
Mflv_0420|M.gilvum_PYR-GCK PPAFFSWFAAGMVLAELTVSPVGWAHRLARRRVLMALLALTAFLIAASPL
Mb0530|M.bovis_AF2122/97 LPRIVTQFAAGALACAAVRRLRPTDRARRIAG-------YLSVLVGVAIV
Rv0517|M.tuberculosis_H37Rv LPRIVTQFAAGALACAAVRRLRPTDRARRIAG-------YLSVLVGVAIV
MAB_2552c|M.abscessus_ATCC_199 LSRFFVVFLAGALFYQYQDKIPAHWSLVVLS-------------------
MSMEG_3429|M.smegmatis_MC2_155 LARFAVVFLAGAMFYQYQHKIPANWWLVALG-------------------
MAV_3274|M.avium_104 IGRFALVFAAGTLLHQFQDKIPARWSLVALS-------------------
* .*
MMAR_4188|M.marinum_M AGAPTTSPSALTEAVVKACFYTVIATLAVAPLALGDQGWYSQLLASRPMV
MUL_4492|M.ulcerans_Agy99 AGAPTTSPSALTEAVVKACFYTVIATLAVAPLALGDQGWYSQLLASRPMV
TH_2230|M.thermoresistible__bu GGEPTTSPNELWEAWAKTGFYTVIATLMVAPLALGNKGWYSRVLGSRPMV
Mvan_4285|M.vanbaalenii_PYR-1 GG-TLAGPDPAWTPIVKALLYAVIATLAVAPVALGSRDSYSRVLASRPMV
Mflv_0420|M.gilvum_PYR-GCK AGREGLHPGSIAQVTLKTVMGAIVAGALLAPLVLDRVDTSHRMLGSPVMV
Mb0530|M.bovis_AF2122/97 GILYLLHAHPLAGVEDSGGVVDVLFVPLVISLAIG-VGSLPALLSTRLMV
Rv0517|M.tuberculosis_H37Rv GILYLLHAHPLAGVEDSGGVVDVLFVPLVISLAIG-VGSLPALLSTRLMV
MAB_2552c|M.abscessus_ATCC_199 VGLVVASG-FTQNYRVLGALPLAYAVIVSGALIRKT--RLRNDFSYGVYI
MSMEG_3429|M.smegmatis_MC2_155 AGIVVASS-FTQNYRLIGALPLAYAIIVSGVLVKRS--RLTNDLSYGVYI
MAV_3274|M.avium_104 AVIVLAAGLLMPNYRVLAAIPLAYAVVVSGALIHHERLRLRTDLSYGVYI
. : :. :
MMAR_4188|M.marinum_M WLGEISYEIFLVHLVTMEFAMVYVVRYRVYTGSMLNLFIAT--MVITIPL
MUL_4492|M.ulcerans_Agy99 WLGEISYEIFLVHLVTMEFAMVYVVRYWVYTGSMLNLFIAT--MVITIPL
TH_2230|M.thermoresistible__bu FLGEISYEIFLIHLILMEVAMVEILRSPVYTGSMFWLFVWT--MVLTIPL
Mvan_4285|M.vanbaalenii_PYR-1 WLGEISYEIFLVHVAVMALTMHLVLGWPLFTGSMPGLIAAT--LALTVPV
Mflv_0420|M.gilvum_PYR-GCK TLGRWSYGLFVWHLAALAMVFPVIGAFP-FNGHFTVVLLLT--LLFGFAI
Mb0530|M.bovis_AF2122/97 FGGQISFCLYMVHELVHTAWGWAVQQYELALQDQPWKWNVVGLLAIALGA
Rv0517|M.tuberculosis_H37Rv FGGQISFCLYMVHELVHTAWGWAVQQYELALQDQPWKWNVVGLLAIALGA
MAB_2552c|M.abscessus_ATCC_199 YAFPIQQLLATFGLARLNPFLFFLLAATATLPIAALSWFVVEKRAMALKA
MSMEG_3429|M.smegmatis_MC2_155 YAFPVQQLLATFGLAALNPFLFFGLSTAAVMPIAAGSWFLVEKRASNLKS
MAV_3274|M.avium_104 YAWPMQQLLAICGLSFLPPVVFAVVAVVVTLPLAALSWFLVEKRALSLKS
. : . .
MMAR_4188|M.marinum_M AWVLHRFTR-------VRSE------------------------------
MUL_4492|M.ulcerans_Agy99 AWVLHRFTR-------VRSE------------------------------
TH_2230|M.thermoresistible__bu AWLLHRFTR-------VRDQ------------------------------
Mvan_4285|M.vanbaalenii_PYR-1 AWLLNRVTRPQIK---ARSDGSNAASALPRCDEASFSAGLSSAAVLAEPV
Mflv_0420|M.gilvum_PYR-GCK AAVSYALVESPCRNALRRWERRNAPTPLDSSITEEIEPEVAR--------
Mb0530|M.bovis_AF2122/97 AILLYHFVEEPDRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVS
Rv0517|M.tuberculosis_H37Rv AILLYHFVEEPGRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVS
MAB_2552c|M.abscessus_ATCC_199 RIFRRSNR--------KPAAQRATVP------------------------
MSMEG_3429|M.smegmatis_MC2_155 RIFRKSKKAAEPSKRPEPAVATGTVEASTRTAESPAIPGEHS--------
MAV_3274|M.avium_104 RIKRRARG-------WGAVVSSGSRISTPGS-------------------
MMAR_4188|M.marinum_M ------
MUL_4492|M.ulcerans_Agy99 ------
TH_2230|M.thermoresistible__bu ------
Mvan_4285|M.vanbaalenii_PYR-1 GRNTGS
Mflv_0420|M.gilvum_PYR-GCK ------
Mb0530|M.bovis_AF2122/97 ARAV--
Rv0517|M.tuberculosis_H37Rv ARAV--
MAB_2552c|M.abscessus_ATCC_199 ------
MSMEG_3429|M.smegmatis_MC2_155 ------
MAV_3274|M.avium_104 ------