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LGRVFDPRNNALNAWRLILATSVILWHTWPLTGHEIPARPITQLLSQVGVDGFFAVSGFLITSSWMRHPN PKTYFTARCLRIFPGLWVCLLITAFVIAPVSVWIKHGTMPSPMSAVAYIINGGLLNPFYPGIGGTPQDVP WPGVWNGSLWTLTFEMGCYIFVAILGVTGLLKYRSTIPVAFVLALCGTAVFGYPAFAMQTIPQMVTRFAV MFAAGALIYQYQDKIPARWSLIALAAGVVLISGLLPNYRVLAAIPLAYLVIASGAMLKRPNLRNDLSYGV YIYAFPIQQLLVIIGLGTLGVFPFFVLATLLTLPLAAMSWFIVEKRTLALKKRKQVVAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1725c | - | - | 100% (340) | putative acetyltransferase |
| M. abscessus ATCC 19977 | MAB_3448 | - | e-158 | 78.13% (343) | putative acetyltransferase |
| M. abscessus ATCC 19977 | MAB_4106c | - | e-128 | 64.55% (347) | acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0233 | - | 3e-08 | 21.95% (369) | integral membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_3267 | - | 2e-06 | 23.90% (272) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0228 | - | 3e-08 | 21.95% (369) | integral membrane acyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0857 | - | 2e-06 | 27.38% (325) | transmembrane acyltransferase |
| M. avium 104 | MAV_3274 | - | 1e-105 | 56.93% (339) | putative acyltransferase |
| M. smegmatis MC2 155 | MSMEG_0390 | - | 1e-131 | 66.57% (338) | putative acyltransferase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0609 | - | 1e-06 | 27.38% (325) | transmembrane acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4875 | - | 4e-07 | 24.71% (340) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0857|M.marinum_M MTIRQDRSASQLRAAQRPGPRIAFRPDIEGLRAIAVVAVVLYHAGIPGIS
MUL_0609|M.ulcerans_Agy99 ---------------------------------------MSCHAGIPGIS
Mb0233|M.bovis_AF2122/97 -------------------------------------------MGPADES
Rv0228|M.tuberculosis_H37Rv -------------------------------------------MGPADES
MAV_3274|M.avium_104 -------------------------------------------MSADPNV
MSMEG_0390|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1725c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4875|M.vanbaalenii_PYR-1 --MTAVSAAPIRVGPRRYVGPGQAIPALDGVRAIAVALVLADHGGVPGLS
Mflv_3267|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0857|M.marinum_M GGYIGVDVFFVISGFLITGLLWSEVTTTNTVALGRFYGARARRLLPAAAT
MUL_0609|M.ulcerans_Agy99 GGYIGVDVFFVISGFLITGLLWREVTTTNTVALGRFYGARARRLLPAAAT
Mb0233|M.bovis_AF2122/97 GAPIRPQTPHRHTVLVTN---------------GQVVGG-TRGFLPAVEG
Rv0228|M.tuberculosis_H37Rv GAPIRPQTPHRHTVLVTN---------------GQVVGG-TRGFLPAVEG
MAV_3274|M.avium_104 SDPTTIAARGPARRRVPG----------------PTLAQVFDTRINALNV
MSMEG_0390|M.smegmatis_MC2_155 ------------------------------------MGKVFDPRNNALNA
MAB_1725c|M.abscessus_ATCC_199 -----------------------------------MLGRVFDPRNNALNA
Mvan_4875|M.vanbaalenii_PYR-1 GGFLGVDVFFVLSGFLITSLLLDEVGRTGRIGLKGFWIRRARRLLPALLV
Mflv_3267|M.gilvum_PYR-GCK ------------------------------------MSRVRTGEIRALSG
*
MMAR_0857|M.marinum_M VGVATAIVSAIVLPPLQARRVFVDGIASALYVGNYRFAVQGTDYMASDLP
MUL_0609|M.ulcerans_Agy99 VGVATAIVSAIVLPPLQARRVFVDGIASALYVGNYRFAVQGTDYMASDLP
Mb0233|M.bovis_AF2122/97 MRACAAVGVVVTHVAFQTG--HSSGVGGRLFG---RFDLAVAVFFAVSG-
Rv0228|M.tuberculosis_H37Rv MRACAAVGVVVTHVAFQTG--HSSGVGGRLFG---RFDLAVAVFFAVSG-
MAV_3274|M.avium_104 WRLVLASGVILQHSWPLTGR-KVHPPYDQLFP-----QVWVDGFFAISG-
MSMEG_0390|M.smegmatis_MC2_155 LRLLLAVGVILWHSWPLSGHGVTYKPLEQLLE-----QVWVDGFFAISG-
MAB_1725c|M.abscessus_ATCC_199 WRLILATSVILWHTWPLTGHEIPARPITQLLS-----QVGVDGFFAVSG-
Mvan_4875|M.vanbaalenii_PYR-1 MVLAVVALRELFSEESTAN-LREDAVAAFFWMSNWVFVAQHTDYFSQGAP
Mflv_3267|M.gilvum_PYR-GCK LRIVAALWVVLFHFRPMLA-ESAPGFTSALAPVLNAGAQGVDLFFILSG-
. : : :: .
MMAR_0857|M.marinum_M PSPFQHYWSLGVEEQFYLVWPALIIATAWLLRR---IGKNNRGATPYAVV
MUL_0609|M.ulcerans_Agy99 PSPFQHYWSLGVEDQFYLVWPALIIATAWLLRR---IGKNNRGATPYAVV
Mb0233|M.bovis_AF2122/97 ----------------FLLWRGHAAAARDLR------SHPRTGPYLRSRV
Rv0228|M.tuberculosis_H37Rv ----------------FLLWRGHAAAARDLR------SHPRTGPYLRSRV
MAV_3274|M.avium_104 ----------------------FLIAASWVR-------NPRLREYVAARA
MSMEG_0390|M.smegmatis_MC2_155 ----------------------FLITSSWLR-------NPRLRDYATARV
MAB_1725c|M.abscessus_ATCC_199 ----------------------FLITSSWMR-------HPNPKTYFTARC
Mvan_4875|M.vanbaalenii_PYR-1 PSPLQHTWSLAVEEQFYVLWP-LLIAAVLAGLA---ALAYRRGVPLSQRV
Mflv_3267|M.gilvum_PYR-GCK ----------------------FVLAWNYLDRMGDSWSTRSTLRFLWLRL
:
MMAR_0857|M.marinum_M LVLVAAASLAAAAIWTRTSPPWAFFSLPTRAWELAVGGLVALTMQQWRRL
MUL_0609|M.ulcerans_Agy99 LVLVAAASLAAAAIWTRTSPPWAFFSLPTRAWELAVGGLVALTMQQWRRL
Mb0233|M.bovis_AF2122/97 ARIMPAYVVAVVVILS---------LLPDADHASLTVWLANLTLTQIY--
Rv0228|M.tuberculosis_H37Rv ARIMPAYVVAVVVILS---------LLPDADHASLTVWLANLTLTQIY--
MAV_3274|M.avium_104 LRILPGLWVCLVVIAF-------------------VIAPIGVAIQGGS--
MSMEG_0390|M.smegmatis_MC2_155 LRIFPGLWVCLLIIAF-------------------VMAPIGVLLQGGS--
MAB_1725c|M.abscessus_ATCC_199 LRIFPGLWVCLLITAF-------------------VIAPVSVWIKHGT--
Mvan_4875|M.vanbaalenii_PYR-1 VRTAVFVLAAGGVVASATATFFLSSDATLNRVYFGTDTRVQALLVGAAAA
Mflv_3267|M.gilvum_PYR-GCK ARVWPVYLVTMHLAAAFAVFTLYIGGFPLPPPVIESLNALSWLKQVFLVQ
MMAR_0857|M.marinum_M PLVPATIVGWGGLALLLLTCTQLGPNTPYPGTAALLPVLGTALVIGSGCV
MUL_0609|M.ulcerans_Agy99 PLVPATIVGWGGLALLLLTCTQLGPNTPYPGTAALLPVLGTALVIGSGCV
Mb0233|M.bovis_AF2122/97 --VPLTLTGG------LTQMWSLSVEVAFYAALPVLALLGRRIPVG----
Rv0228|M.tuberculosis_H37Rv --VPLTLTGG------LTQMWSLSVEVAFYAALPVLALLGRRIPVG----
MAV_3274|M.avium_104 --AAKLLMSRAPIEYVLHNAVLHVFFAGIDGTPRHVPFPG----------
MSMEG_0390|M.smegmatis_MC2_155 --VSGLMSSYAPIEYVLNNAVLNVYYAGINGTPQGIPWPG----------
MAB_1725c|M.abscessus_ATCC_199 --MPSPMS---AVAYIINGGLLNPFYPGIGGTPQDVPWPG----------
Mvan_4875|M.vanbaalenii_PYR-1 ALVVRDWRGLTAGLVIFRSRWARWVAWSLPAVGLVVLFSAARMATG----
Mflv_3267|M.gilvum_PYR-GCK LWFQPYFDGSSWNGPAWSISAEWLAYLLFGGLVLIIFRIASATRAR----
. : .
MMAR_0857|M.marinum_M TGSMGVGRVLCRPVMRAIGRVSYSWYLWHWPVLLLLPPLLGDPAGLPARL
MUL_0609|M.ulcerans_Agy99 TGAMGVGRVLCRPVMRAIGRVSYSWYLWHWPVLLLLPPLLGDPAGLPARL
Mb0233|M.bovis_AF2122/97 -----------------------------------------------ARV
Rv0228|M.tuberculosis_H37Rv -----------------------------------------------ARV
MAV_3274|M.avium_104 -------------------------------------------------V
MSMEG_0390|M.smegmatis_MC2_155 -------------------------------------------------V
MAB_1725c|M.abscessus_ATCC_199 -------------------------------------------------V
Mvan_4875|M.vanbaalenii_PYR-1 ---------------------------------------------SAAEF
Mflv_3267|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0857|M.marinum_M AATTVSAGLAVITMYLVENPGRFTAALRSVRASLTLAAAATAAA-----A
MUL_0609|M.ulcerans_Agy99 AATTVSAGLAVITMYLVENPGRFTAALRSVRASLTLAAAATAAA-----A
Mb0233|M.bovis_AF2122/97 PAIAALAALSWAWGWLPLDAGSGINPLTWPPAFFSWFAAG----------
Rv0228|M.tuberculosis_H37Rv PAIAALAALSWAWGWLPLDAGSGINPLTWPPAFFSWFAAG----------
MAV_3274|M.avium_104 WDGVLWTLIFEIFCYIAIAVAGVAGLLKRRWPAVVVFILL----------
MSMEG_0390|M.smegmatis_MC2_155 WNGSLWTLVFEMICYIAVAVLGIVGLLKRRWVIPAIFVLT----------
MAB_1725c|M.abscessus_ATCC_199 WNGSLWTLTFEMGCYIFVAILGVTGLLKYRSTIPVAFVLA----------
Mvan_4875|M.vanbaalenii_PYR-1 RSGLLIVVALAAVLVIAPVALAQDGPVARLLSAGPLVGLGAISYGVYLWH
Mflv_3267|M.gilvum_PYR-GCK GLMWLAIAAALAPTLLLLAHGVFYTPWSWLPRIIMQFTAG----------
:
MMAR_0857|M.marinum_M CACALLLTAIPVPVGHGTAAPEAKIIALPPAALPQRALSPQEAAVQQAFA
MUL_0609|M.ulcerans_Agy99 CACALLLTAIPVPVGHGTAASEAKIIALPPAALPQRALSPQEAAVQQAFA
Mb0233|M.bovis_AF2122/97 ------------------------------MLLAEWAYSPVGLPHRWARR
Rv0228|M.tuberculosis_H37Rv ------------------------------MLLAEWAYSPVGLPHRWARR
MAV_3274|M.avium_104 -----------------------------------VVFSALVAYPV-EVQ
MSMEG_0390|M.smegmatis_MC2_155 -----------------------------------LCATAYFSYPVFAMQ
MAB_1725c|M.abscessus_ATCC_199 -----------------------------------LCGTAVFGYPAFAMQ
Mvan_4875|M.vanbaalenii_PYR-1 WPIFLVLNGERTGIEGWELFALRCAATVAVAAVSWWLIEQPIREWRPAFV
Mflv_3267|M.gilvum_PYR-GCK ----------------------------------ALACAAVRKLVLTEST
MMAR_0857|M.marinum_M AVRAAVAASAGLGAVPSNLNPPLAAAPGD---KAAVFVNGCLRSWRDLGQ
MUL_0609|M.ulcerans_Agy99 AVRAAVAASAGLGAVPSTLNPPLAAAPGD---KAAVFVNGCLRSWRDLAQ
Mb0233|M.bovis_AF2122/97 RVAMAVTALLGYLVAASPLAGPEGLVPGT---AAQFAVKTAMGSLVAFAL
Rv0228|M.tuberculosis_H37Rv RVAMAVTALLGYLVAASPLAGPEGLVPGT---AAQFAVKTAMGSLVAFAL
MAV_3274|M.avium_104 TVFQMIGRFALVFAAGTLLHQFQDKIPAR---WSLVALSAVIVLAAGLLM
MSMEG_0390|M.smegmatis_MC2_155 TIPQMVARFAVMFAAGALIHQYRDVIPAR---WSLVGIAVVLVLASGFLS
MAB_1725c|M.abscessus_ATCC_199 TIPQMVTRFAVMFAAGALIYQYQDKIPAR---WSLIALAAGVVLISGLLP
Mvan_4875|M.vanbaalenii_PYR-1 PMLPLAAATAATAAVVTMTVLPVRMVPATPEPGPEVDIAALVGAEVPVEV
Mflv_3267|M.gilvum_PYR-GCK RRAAGIASLLLGVAIVGGLYALDTWPPGDMLDAGGLVDVLFVPLVIALSI
. *. . : .
MMAR_0857|M.marinum_M SECATADTASPTTVALVGDSHAAMWDPALQLVAEQRHWRLETLAKVTCPM
MUL_0609|M.ulcerans_Agy99 SECATADTASPTTVALVGDSHAAMWDPALQLVAEQRHWRLETLAKVTCPM
Mb0233|M.bovis_AF2122/97 VAPLVLDRPD-TSHRLLGSPAMVTLG---RWSYGLFIWHLAALAMVFPVI
Rv0228|M.tuberculosis_H37Rv VAPLVLDRPD-TSHRLLGSPAMVTLG---RWSYGLFIWHLAALAMVFPVI
MAV_3274|M.avium_104 PNYRVLAAIPLAYAVVVSGALIHHERLRLRTDLSYGVYIYAWPMQQLLAI
MSMEG_0390|M.smegmatis_MC2_155 -NYRVIGALPLAYAVIVAGALLRNRRLNLRNDLSYGVYIYAFPVQQLLAI
MAB_1725c|M.abscessus_ATCC_199 -NYRVLAAIPLAYLVIASGAMLK--RPNLRNDLSYGVYIYAFPIQQLLVI
Mvan_4875|M.vanbaalenii_PYR-1 TRAPRPSAPGDLRVAVFGDSIAWTLMRYLPETPGLDFADYTTIGCGIARG
Mflv_3267|M.gilvum_PYR-GCK GAGTLPAFLSTRVMVYLG---HISFGLYMVHEIVHTMWNWAVLQFDIVLT
.
MMAR_0857|M.marinum_M QDLPILSPYLGREYTECEQWRGEIMGRLQSERPRLVVLSMSRRYQPD---
MUL_0609|M.ulcerans_Agy99 QDLPILSPYLGREYTECEQWRGEIMGRLQSERPRLVVLSMSRRYQPD---
Mb0233|M.bovis_AF2122/97 GAFPFTG-----------------------RMPTVLVLTLIFG-------
Rv0228|M.tuberculosis_H37Rv GAFPFTG-----------------------RMPTVLVLTLIFG-------
MAV_3274|M.avium_104 CGLSFLP-----------------------PVVFAVVAVVVT--------
MSMEG_0390|M.smegmatis_MC2_155 LGFANSQ-----------------------PFLFFVIATAAT--------
MAB_1725c|M.abscessus_ATCC_199 IGLGTLG-----------------------VFPFFVLATLLT--------
Mvan_4875|M.vanbaalenii_PYR-1 GPYEYVG-QELPQKPECDEWPARWAQRVGHEKPDVVLLMVGRWEVVDRMM
Mflv_3267|M.gilvum_PYR-GCK PSW----------------------------WAKLVVLGLILFAG-----
::
MMAR_0857|M.marinum_M ------FSFASYDPAWIDTLNRTVAQLRRNGSSVLVLGPVADPQSSVPTC
MUL_0609|M.ulcerans_Agy99 ------FSFASYDPAWIDTLNRTVAQLRRNGSSVLVLGPVADPQSSVPTC
Mb0233|M.bovis_AF2122/97 ------FAIAAVSYALVESPCREALRRWER--------------------
Rv0228|M.tuberculosis_H37Rv ------FAIAAVSYALVESPCREALRRWER--------------------
MAV_3274|M.avium_104 ------LPLAALSWFLVEKRALSLKSRIKRRARG----------------
MSMEG_0390|M.smegmatis_MC2_155 ------VPLAALSWFLVEKRAIALKSRLKRRRT-----------------
MAB_1725c|M.abscessus_ATCC_199 ------LPLAAMSWFIVEKRTLALKKRKQ---------------------
Mvan_4875|M.vanbaalenii_PYR-1 EGQWTHIGEAGYDAYLRGELNRALDILGSTGARVVVTTEPYN--------
Mflv_3267|M.gilvum_PYR-GCK -------IAAAVLYHVVEEPARRWMRRMIEPERP----------------
*.
MMAR_0857|M.marinum_M LSAHLDDAGACAPSRSAATNAGGVAAEQTATEAGGGHYADLTDLFCTPDR
MUL_0609|M.ulcerans_Agy99 LSAHLDDAGACAPSRSAATNAGGVAAEQTATEAGGGHYADLTDLFCTPDR
Mb0233|M.bovis_AF2122/97 --------------RNEPISVGELQADAIAP-------------------
Rv0228|M.tuberculosis_H37Rv --------------RNEPISVGELQADAIAP-------------------
MAV_3274|M.avium_104 --------------WGAVVSSGSRISTPGS--------------------
MSMEG_0390|M.smegmatis_MC2_155 ---------------DTVADTTQKVSDRGAG-------------------
MAB_1725c|M.abscessus_ATCC_199 -----------------VVAV-----------------------------
Mvan_4875|M.vanbaalenii_PYR-1 RRAEKPDGSLYPEDQPKRVETWNALLRSVVDKRPNATVLDLNKKLSPNGY
Mflv_3267|M.gilvum_PYR-GCK -------------RAAAASEPSTGRLQSVAARAG----------------
MMAR_0857|M.marinum_M CPTIIGNTLVFRDDNHLTTEYAQLLAPVIGALADRALAAG
MUL_0609|M.ulcerans_Agy99 CPTIIGNTLVFRDDNHLTTEYAQLLAPVIGALADRALAAG
Mb0233|M.bovis_AF2122/97 ----------------------------------------
Rv0228|M.tuberculosis_H37Rv ----------------------------------------
MAV_3274|M.avium_104 ----------------------------------------
MSMEG_0390|M.smegmatis_MC2_155 ----------------------------------------
MAB_1725c|M.abscessus_ATCC_199 ----------------------------------------
Mvan_4875|M.vanbaalenii_PYR-1 YQTRVDGIRVRSDGVHPTPEAVEWLTPWLVDALKPE----
Mflv_3267|M.gilvum_PYR-GCK ----------------------------------------