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SDTPAITRRDRDRFYEPPHLDDGGAPGDLLRAAPMTARLLPGLAMSARAWRVLYRSTDAAGSPIAVSGVI LVPNTANPASPRPLLGFAPGTQGLARSAAALSRQLEVGLEYEAWFLAAAVRRGWVVAVTDYPGLGTPGLH PYVVGKTNGRAVLDIMRAARNLPQTGLRADCATGIYGYSEGGNSAGWAAQLEPGYAPDVRLRAVAVGAAP VDFPELVTDLDGGLFSFLLLYAGLGLNSAYPDLRFHDYLNRGGRLAAAVLRRTHILAAIVLGLILPKRRG RYLSADPFVEPDWAAQLRDNSLGYLAPAAPVLVGIGRQDQVIPYRQAQLLLRRWTALGANVREHPIRFGE HLTAAPQFAKAGFAFLAEHLSNPETRAPVQERQAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2538c | - | - | 100% (386) | hypothetical protein MAB_2538c |
| M. abscessus ATCC 19977 | MAB_0918c | - | 1e-27 | 28.03% (421) | triacylglycerol lipase |
| M. abscessus ATCC 19977 | MAB_4134 | - | 3e-27 | 28.33% (353) | putative lipase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1618c | - | 9e-29 | 27.76% (371) | hypothetical protein Mb1618c |
| M. gilvum PYR-GCK | Mflv_3621 | - | 9e-31 | 28.30% (371) | triacylglycerol lipase |
| M. tuberculosis H37Rv | Rv1592c | - | 9e-29 | 27.76% (371) | hypothetical protein Rv1592c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1029 | - | 3e-48 | 36.60% (347) | lipase |
| M. avium 104 | MAV_5251 | - | 4e-47 | 35.97% (367) | secretory lipase family protein |
| M. smegmatis MC2 155 | MSMEG_3197 | - | 8e-29 | 28.23% (372) | lipase |
| M. thermoresistible (build 8) | TH_3043 | - | 2e-45 | 34.84% (353) | PUTATIVE Triacylglycerol lipase |
| M. ulcerans Agy99 | MUL_0787 | - | 7e-48 | 37.50% (352) | lipase |
| M. vanbaalenii PYR-1 | Mvan_2796 | - | 2e-30 | 26.65% (379) | triacylglycerol lipase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1618c|M.bovis_AF2122/97 --------------------MVEPGNLAGATGAEWIGRPPHEELQRKVRP
Rv1592c|M.tuberculosis_H37Rv --------------------MVEPGNLAGATGAEWIGRPPHEELQRKVRP
MSMEG_3197|M.smegmatis_MC2_155 ---------------------MDLSSAAKAADAEWIGRAPHEELDRDARP
Mflv_3621|M.gilvum_PYR-GCK ---------------------MDLGNVARSTGAEWIGQPRHEELRPRTRP
Mvan_2796|M.vanbaalenii_PYR-1 ---------------------MDLGNVARSTGAEWIGQPFHEPLRPRSRP
MMAR_1029|M.marinum_M ------------MRAARGRLQSRLQVVVVAMLSCATITVVAPDSARADGG
MUL_0787|M.ulcerans_Agy99 MVIEKRDLFVRGMRAARGRLQSRLQVVVVAMLSCATITVVAPDSARADGG
MAV_5251|M.avium_104 ------------MRDCY-RSVMRRVAGVFAALVLMAGTLTGPAIARADG-
TH_3043|M.thermoresistible__bu --------------------MVRGFAGSVCVLLIVSMGMSSP-LARAEDP
MAB_2538c|M.abscessus_ATCC_199 -------------------------------------MSDTPAITRRDR-
Mb1618c|M.bovis_AF2122/97 -----LLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIP---QPVT
Rv1592c|M.tuberculosis_H37Rv -----LLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIP---QPVT
MSMEG_3197|M.smegmatis_MC2_155 -----GLPGEDPFYLPPAGYHHAEPGTVLRSRDVELAFLGLVP---QALH
Mflv_3621|M.gilvum_PYR-GCK -----VIPADDPFYEPPEGYEHARPGTVLRSRDVELAFLGLIP---QKFS
Mvan_2796|M.vanbaalenii_PYR-1 -----MIPAKDDFYEPPAGFEHARPGTVLRSRDVELAFLGVIP---QKFT
MMAR_1029|M.marinum_M FESEGDQSQYDQFYTPPDPLPPGEPGDVIRTEPSRLVLEPSGQLGAIMAT
MUL_0787|M.ulcerans_Agy99 FESEGDQSQYDQFYTPPDPLPPGEPGDVIRTEPSRLALEPSGQLGAIMAT
MAV_5251|M.avium_104 -----DEPQYADFYTPPDPLPPGRPGDLIRTEPSRLVLEPSGQLGAIMAT
TH_3043|M.thermoresistible__bu FT---HEQKYTAFYTPPDPLPPGEPGDLIRTEPARLVLEPSGQLGAIMAT
MAB_2538c|M.abscessus_ATCC_199 ----------DRFYEPPHLDDGGAPGDLLRAAPMTARLLPG---LAMSAR
** ** . ** ::*: :
Mb1618c|M.bovis_AF2122/97 ATQLLYRTTNMYGNPEATVTTVIVP-AELAPGQTCPLLSYQCAIDAMSSR
Rv1592c|M.tuberculosis_H37Rv ATQLLYRTTNMYGNPEATVTTVIVP-AELAPGQTCPLLSYQCAIDAMSSR
MSMEG_3197|M.smegmatis_MC2_155 ATQLLYRTTDRNGAPEAAVTTVIMP-PDARAG--CPIVSYQCAIDAISAT
Mflv_3621|M.gilvum_PYR-GCK ATQLLYRTTDLYGQPQATVTTVLAP-TERTDRRPLPIVSYQCAIDAVAGR
Mvan_2796|M.vanbaalenii_PYR-1 ATQLLYRTTDLNGEAQATVTTVVVP-SERTSDGPLPIVSYQCAIDAVAGR
MMAR_1029|M.marinum_M GTRIMYRSTDTRGNPIAVTGTYFEPDNPWPGSGPRPLLSYAPGTVGQGDQ
MUL_0787|M.ulcerans_Agy99 GTRIMYRSTDTRGNPIAVTGTYFEPDNPWPGSGPRPLLRYAPGTVGQGDQ
MAV_5251|M.avium_104 GTRIMYRSTDTRGNPIAVTGTYFEPYNDWPYGGPRPLISYAPGTQGQGNQ
TH_3043|M.thermoresistible__bu GTRIMYRSTDSRGNPNVVTGMYFEPHNDWPHGGPRPLIAYGPGTQGQGDQ
MAB_2538c|M.abscessus_ATCC_199 AWRVLYRSTDAAGSPIAVSGVILVPNTANPAS-PRPLLGFAPGTQG----
. :::**:*: * . .. . * *:: : . .
Mb1618c|M.bovis_AF2122/97 CFPSYALRR---RAKALGSLTQMELLMISAALAEGWAVSVPDHEGPKGLW
Rv1592c|M.tuberculosis_H37Rv CFPSYALRR---RAKALGSLTQMELLMISAALAEGWAVSVPDHEGPKGLW
MSMEG_3197|M.smegmatis_MC2_155 CFPSYALRR---HAKVTGGLAQFELLLITAALAEGWAVSVPDHEGLDGMW
Mflv_3621|M.gilvum_PYR-GCK CFPSYALRR---GAKALGAVAQFEFLLIAAALAEGWAVSVPDHEGTTGMW
Mvan_2796|M.vanbaalenii_PYR-1 CFPSYALRR---GAKALGSFAQFEFLLVAAALAEGWAVSVPDHEGTSGMW
MMAR_1029|M.marinum_M CALSRVFNQGIHWSPWLDLMVNYEETFVATMVARGFAIVMTDYEGLGTPG
MUL_0787|M.ulcerans_Agy99 CALSRVFNQGIHWSPWLDLMVNYEETFVATMVARGFAIVMTDYEGLGTPG
MAV_5251|M.avium_104 CAPSRMFNQGIHYSGGWDIMFNYEELFVATMVARGFAIVMTDYQGLGTPP
TH_3043|M.thermoresistible__bu CAPSRMFSEGIHWTSGADIMFNYEEMFVATMVARGFAIVMTDYEGLGTPG
MAB_2538c|M.abscessus_ATCC_199 -----LARSAAALSRQLEVGLEYEAWFLAAAVRRGWVVAVTDYPGLGTPG
: : * :::: : .*:.: :.*: *
Mb1618c|M.bovis_AF2122/97 GSPYEP----GYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAWA
Rv1592c|M.tuberculosis_H37Rv GSPYEP----GYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAWA
MSMEG_3197|M.smegmatis_MC2_155 GAPYEP----GYHVLDGLRAALNSERLPLTDASPIGLWGYSGGGLASGWA
Mflv_3621|M.gilvum_PYR-GCK GAPFEP----GYHVLDGIRAAVNHRPLGLAEDAPVGLWGYSGGGLASAWA
Mvan_2796|M.vanbaalenii_PYR-1 GAPHEP----GYHVLDGVRAALNHGPLGLSPDAPVGLWGYSGGGLASAWA
MMAR_1029|M.marinum_M THTYVNRLAEGHAVLDAARAAQRLPGTSLDPHGPVAFWGYSQGGGAAASA
MUL_0787|M.ulcerans_Agy99 THTYVNRLAEGHAVLDAARAAQRLPGTSLDPHGPVAFWGYSQGGGAAASA
MAV_5251|M.avium_104 MHTYVGRVAEGQAVLDAARAAMRLPGTSLDPHGPVAFWGYSQGGGATASA
TH_3043|M.thermoresistible__bu VHTYVNRLAQGHALIDAARAAKRLPGTSLDPDGPVAFWGYSQGGGAAASA
MAB_2538c|M.abscessus_ATCC_199 LHPYVVGKTNGRAVLDIMRAARNLPQTGLRADCATGIYGYSEGGNSAGWA
.. * ::* *** . * . .::*** ** ::. *
Mb1618c|M.bovis_AF2122/97 AEACGEYAPDLDIVGAVLGSPVGDLGHTFRRLNGTLLAGLPALVVAALQH
Rv1592c|M.tuberculosis_H37Rv AEACGEYAPDLDIVGAVLGSPVGDLGHTFRRLNGTLLAGLPALVVAALQH
MSMEG_3197|M.smegmatis_MC2_155 AEMSGSYAPELNIVGAVLGSPVGDLGHTFRRLNGTVFSGLPALVVAALAD
Mflv_3621|M.gilvum_PYR-GCK AEVHDSYAPELNVVGAVLGSPVGDLGHAFRRLNGSIYSGLPAMVVAALTH
Mvan_2796|M.vanbaalenii_PYR-1 AEVQDAYAPELNVVGAVLGSPVGDLGHTFRRLNGSIYAGLPALVVAALTH
MMAR_1029|M.marinum_M AELVSSYAPELDVVGTYAGAPPADLVEMLPYMDGNVLVGAAGYLINGFIY
MUL_0787|M.ulcerans_Agy99 AELVSSYAPELDVVGTYAGAPPADLVEMLPYMDGNVLVGAAGCLINGFIY
MAV_5251|M.avium_104 AELAAQYAPDLHIVGTYAGAPPADLKELLPYADGSALVGVVGYALNSVMA
TH_3043|M.thermoresistible__bu AELASTYGPELDVVGTYAGSPPADLVALLPFADGSVLVGALGYALNGAIA
MAB_2538c|M.abscessus_ATCC_199 AQLEPGYAPDVRLRAVAVGAAPVDFPELVTDLDGGLFSFLLLYAGLGLNS
*: *.*:: : .. *:. *: . :* .
Mb1618c|M.bovis_AF2122/97 SYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGDFLDEPLE
Rv1592c|M.tuberculosis_H37Rv SYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGDFLDEPLE
MSMEG_3197|M.smegmatis_MC2_155 IYPGLNRVIAEHATTEGRKLLQRLHKMSTIEAVLRLARKDMDDLVDLPLE
Mflv_3621|M.gilvum_PYR-GCK VYPDLNRIIQQHATVEGKAMLARIEKMTTAHAMLSLVGKDMAHWVDRPLE
Mvan_2796|M.vanbaalenii_PYR-1 IYPDLHRVIQEHATEDGKVMLARIEKMTTAHAMISLVGRDMAHMIDRPLE
MMAR_1029|M.marinum_M AYPELADAIHERMTPRGEDLLAKTRHQCVQETSFKFMFRHLRGYFTKDLD
MUL_0787|M.ulcerans_Agy99 AYPELADAIHERMTPRGEDLLAKTRHQCVEETSFKFMFRHLRGYFTKDLD
MAV_5251|M.avium_104 AYPEFADAIRSKMTPRGLAMLESVSRQCVGQTLLDFMFRHIQPYFTEDIN
TH_3043|M.thermoresistible__bu AYPEAEEKIRATLTPRGAHMLDEVKDQCVGETLMKFAFRHLQPYFNVDIF
MAB_2538c|M.abscessus_ATCC_199 AYPDLRFHDYLNRGGRLAAAVLRRTHILAAIVLGLILPKRRGRYLSADP-
** : . . : : .
Mb1618c|M.bovis_AF2122/97 DILSTPEVSHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDIDALADSYT
Rv1592c|M.tuberculosis_H37Rv DILSTPEISHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDIDALADSYT
MSMEG_3197|M.smegmatis_MC2_155 QILDSPEVTEVFDDIKLGVATPNPPVLLIQAVHDELISVSSIDELAEKYL
Mflv_3621|M.gilvum_PYR-GCK EILLTPEVQHVFDSIKLGTSAPKVPVLIVQAVHDRIISVDDIDELTETYT
Mvan_2796|M.vanbaalenii_PYR-1 EILLSPEVQHVFDSIKLGTAAPKVPLLIVQAVHDRIISVDDIDALTETYT
MMAR_1029|M.marinum_M QLVREEPFKTLFEAQRLGRHQPSAPVLIVNNRYDPLVPWTQASQLGRDWC
MUL_0787|M.ulcerans_Agy99 QLVREEPFKTLFEAQRLGRHQPSAPVLIVNNRYDPLVPWTQASQLGRDWC
MAV_5251|M.avium_104 QLVNEEPFNSLFEAQRIGRYKPNAPVLINSNRYDPLVPWTAANQLGRDWC
TH_3043|M.thermoresistible__bu TAVEEEPFKSLFELQRLGGLKPEGPVLINANRFDPLVPWAPAMQMGRDWC
MAB_2538c|M.abscessus_ATCC_199 --FVEPDWAAQLRDNSLGYLAPAAPVLVGIGRQDQVIPYRQAQLLLRRWT
. : :* * *:*: * :: : :
Mb1618c|M.bovis_AF2122/97 AGGANVT--------YHRDLFSEHVSLHPLSAPMTLRWLTDRFAGKPLTD
Rv1592c|M.tuberculosis_H37Rv AGGANVT--------YHRDLFSEHVSLHPLSAPMTLRWLTDRFAGKPLTD
MSMEG_3197|M.smegmatis_MC2_155 TGGASVT--------YHRDLFSEHLLLHPMSAPMALRWLTDRFAARPLTA
Mflv_3621|M.gilvum_PYR-GCK AGGASVT--------YHRDMFSEHLLLHPMSAPMTLRWLRDRFAGRPISA
Mvan_2796|M.vanbaalenii_PYR-1 SGGASVT--------YHRDMLSEHLLLHPMSAPMTLRWLRDRFAGRPLRT
MMAR_1029|M.marinum_M AQGAQVEFWTNEEPPFLNKASVNHALTFWVDGERALQWVADRFNGLPAAP
MUL_0787|M.ulcerans_Agy99 AQGAQVEFWTNEEPPFLNKASVNHALTFWVDGERALQWVADRFNGRPAAP
MAV_5251|M.avium_104 AQGADVEFRTNEEPPFLNKLVINHALPMLVDGEPAMQWIAARFRGEPTAP
TH_3043|M.thermoresistible__bu AMGADVEARTNEQPPLFNKLIVNHGLPMLVDGEPAMQWIADRFKGVPTAP
MAB_2538c|M.abscessus_ATCC_199 ALGANVR----EHPIRFGEHLTAAPQFAKAGFAFLAEHLSNPETRAPVQE
: **.* . . . : *
Mb1618c|M.bovis_AF2122/97 HRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL-----
Rv1592c|M.tuberculosis_H37Rv HRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL-----
MSMEG_3197|M.smegmatis_MC2_155 NLVRSKWPTLLNPVTYVGMARLAGIAAKVVTGRALRRSPL-----
Mflv_3621|M.gilvum_PYR-GCK HIARTKWPTLLNPSTYRGMLTLGKITAKVVLGRRVERQPLSQFDL
Mvan_2796|M.vanbaalenii_PYR-1 HISRTKWPTLLNPSTYRGMLTLGKITAKVMLGRRVERQPLSRFDQ
MMAR_1029|M.marinum_M NCGQF----------------------------------------
MUL_0787|M.ulcerans_Agy99 NCGQF----------------------------------------
MAV_5251|M.avium_104 NCGQF----------------------------------------
TH_3043|M.thermoresistible__bu NCGRF----------------------------------------
MAB_2538c|M.abscessus_ATCC_199 RQAG-----------------------------------------
.