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VTTGATNERKPEQARPPREEWETRDQVPLLPSRDPFYQPPVGFRTLPAGAVLRWRRVDLALFGRIRQHVD AWQLLYRTNSMHHEPEVAVTTVVLPARVRAPAHRPLLAYQCAIDAVADKCFPSYALRYGSRAIGAVPQFE WPLIAAAVARGWAVSISDHEGQDGCFVAPREPGYRILDGVRAAMSFEPLGLDQSTPVGIWGYSGGGMASS WAAEMAPAYAPEIGIVGAVLGAPVSDPGQLAVRLNATAFSGLTAIGIASLRRCYAGLDARINAHIDAEGQ QILAAASQLDTVRAGARFAKQDFNNHCDISLAELLTQPEIVEVFDDVRLGQHVPACPMLVIHPQHDQIID VRDVDAQVQRYLAADGHVSYVRDHCSEHISLMLLSAPLALNWLKNRFRGTGTSNAQNIPVFSIALSAKAI RGYLSILATMLRAVLARPLGPTTARSQHRI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4134 | - | - | 100% (450) | putative lipase |
| M. abscessus ATCC 19977 | MAB_2676 | - | 2e-97 | 44.72% (398) | hypothetical protein MAB_2676 |
| M. abscessus ATCC 19977 | MAB_1392c | - | 2e-83 | 40.62% (421) | hypothetical protein MAB_1392c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1618c | - | 1e-107 | 50.13% (385) | hypothetical protein Mb1618c |
| M. gilvum PYR-GCK | Mflv_3621 | - | 1e-104 | 45.63% (423) | triacylglycerol lipase |
| M. tuberculosis H37Rv | Rv1592c | - | 1e-107 | 50.39% (385) | hypothetical protein Rv1592c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2389 | - | 1e-110 | 51.69% (385) | hypothetical protein MMAR_2389 |
| M. avium 104 | MAV_3194 | - | 1e-109 | 51.30% (386) | secretory lipase family protein |
| M. smegmatis MC2 155 | MSMEG_3197 | - | 1e-104 | 49.35% (383) | lipase |
| M. thermoresistible (build 8) | TH_2810 | - | 1e-99 | 48.39% (372) | PUTATIVE Triacylglycerol lipase |
| M. ulcerans Agy99 | MUL_1566 | - | 1e-110 | 51.43% (385) | hypothetical protein MUL_1566 |
| M. vanbaalenii PYR-1 | Mvan_2796 | - | 1e-103 | 45.12% (410) | triacylglycerol lipase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1618c|M.bovis_AF2122/97 ---------MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFP
Rv1592c|M.tuberculosis_H37Rv ---------MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFP
MMAR_2389|M.marinum_M MPKAMKGALMVKLGSLADARAAEWIGRPPHEELQRKVRPLLPSDDPFYDP
MUL_1566|M.ulcerans_Agy99 ---------MVKLGSLADARAAGWIGRPPHEELQRKVRPLLPSDDPFYDP
MAV_3194|M.avium_104 ---------MAELGNLAGTHGAEWIARPPHEELQRKVRPLLPSDDPFYQP
MSMEG_3197|M.smegmatis_MC2_155 ----------MDLSSAAKAADAEWIGRAPHEELDRDARPGLPGEDPFYLP
Mflv_3621|M.gilvum_PYR-GCK ----------MDLGNVARSTGAEWIGQPRHEELRPRTRPVIPADDPFYEP
Mvan_2796|M.vanbaalenii_PYR-1 ----------MDLGNVARSTGAEWIGQPFHEPLRPRSRPMIPAKDDFYEP
TH_2810|M.thermoresistible__bu ----------MDLGSAAQSTGAEWIGRPTHEALR-RTRPILPERDPFYEP
MAB_4134|M.abscessus_ATCC_1997 ----------MTTG-ATNERKPEQARPPREEWETRDQVPLLPSRDPFYQP
. : . . .* * :* * ** *
Mb1618c|M.bovis_AF2122/97 PAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRTTNMYGNPEATV
Rv1592c|M.tuberculosis_H37Rv PAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRTTNMYGNPEATV
MMAR_2389|M.marinum_M PAGYHHAEPGTVLRSREVELAFLGLIPQSITATQLLYRTTDMYGNPEATV
MUL_1566|M.ulcerans_Agy99 PAGYHHAEPGTVLRSREVELAFLGLIPQSITATQLLYRTTDMYGNPEATV
MAV_3194|M.avium_104 PLGFQHAEPGTVLRSRDVELAFLGLIPQPIKAVQLLYRTMDMNGEPEATV
MSMEG_3197|M.smegmatis_MC2_155 PAGYHHAEPGTVLRSRDVELAFLGLVPQALHATQLLYRTTDRNGAPEAAV
Mflv_3621|M.gilvum_PYR-GCK PEGYEHARPGTVLRSRDVELAFLGLIPQKFSATQLLYRTTDLYGQPQATV
Mvan_2796|M.vanbaalenii_PYR-1 PAGFEHARPGTVLRSRDVELAFLGVIPQKFTATQLLYRTTDLNGEAQATV
TH_2810|M.thermoresistible__bu PPGFEHARPGTVLRSRDVELAFMGLIPQKFTATQLLYRTTGFDGRPRATV
MAB_4134|M.abscessus_ATCC_1997 PVGFRTLPAGAVLRWRRVDLALFGRIRQHVDAWQLLYRTNSMHHEPEVAV
* *:. .*:*** * *:**::* : * . * ****** . ...:*
Mb1618c|M.bovis_AF2122/97 TTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQM
Rv1592c|M.tuberculosis_H37Rv TTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQM
MMAR_2389|M.marinum_M TTVILPAEVAPGQTYPLLSYQCAIDAMSSRCFPSYALRRGAKAIGSLTQL
MUL_1566|M.ulcerans_Agy99 TTVILPAEVAPGQTYPLLSYQCAIDAMSSRCFPSYALRRGAKAIGSLTQL
MAV_3194|M.avium_104 TTVIVPADAVPGRPCPLLSYQCAIDAVSSRCFPSYALRRRAKALGSIGQF
MSMEG_3197|M.smegmatis_MC2_155 TTVIMPPDARAG--CPIVSYQCAIDAISATCFPSYALRRHAKVTGGLAQF
Mflv_3621|M.gilvum_PYR-GCK TTVLAPTERTDRRPLPIVSYQCAIDAVAGRCFPSYALRRGAKALGAVAQF
Mvan_2796|M.vanbaalenii_PYR-1 TTVVVPSERTSDGPLPIVSYQCAIDAVAGRCFPSYALRRGAKALGSFAQF
TH_2810|M.thermoresistible__bu TTVVVPAERDKNGRCPVVSYQCAIDAVTSRCFPSYALRRGARAVGALAQF
MAB_4134|M.abscessus_ATCC_1997 TTVVLPARVRAPAHRPLLAYQCAIDAVADKCFPSYALRYGSRAIGAVPQF
***: *. *:::*******:: ******** ::. *.. *:
Mb1618c|M.bovis_AF2122/97 ELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLDGIRAALNSERV
Rv1592c|M.tuberculosis_H37Rv ELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLDGIRAALNSERV
MMAR_2389|M.marinum_M ELLLITAAVAEGWAVSVPDHEGVRGLWGTPYEPGYRVLDGIRAALSAERL
MUL_1566|M.ulcerans_Agy99 ELLLITAAVAEGWAVSVPDHEGVRGLWGTPYEPGYRVLDGIRAALSAERL
MAV_3194|M.avium_104 ELFLITAAVAEGWAVSVPDHEGLRGLWGAPYEPGYRVLDGIRAALGSERL
MSMEG_3197|M.smegmatis_MC2_155 ELLLITAALAEGWAVSVPDHEGLDGMWGAPYEPGYHVLDGLRAALNSERL
Mflv_3621|M.gilvum_PYR-GCK EFLLIAAALAEGWAVSVPDHEGTTGMWGAPFEPGYHVLDGIRAAVNHRPL
Mvan_2796|M.vanbaalenii_PYR-1 EFLLVAAALAEGWAVSVPDHEGTSGMWGAPHEPGYHVLDGVRAALNHGPL
TH_2810|M.thermoresistible__bu EFLLIAAALAEGWAVSVPDHEGPDGSWGAPLEPGYHILDGLRAALGYERL
MAB_4134|M.abscessus_ATCC_1997 EWPLIAAAVARGWAVSISDHEGQDGCFVAPREPGYRILDGVRAAMSFEPL
* :::**:*.*****:.**** * : :* ****::***:***:. :
Mb1618c|M.bovis_AF2122/97 GLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLGH
Rv1592c|M.tuberculosis_H37Rv GLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLGH
MMAR_2389|M.marinum_M ALPQSAPIGLWGYSGGGLASAWAAEMCGEYAPELNIVGAVLGSPVGDLGN
MUL_1566|M.ulcerans_Agy99 ALPQSAPIGLWGYSGGGLASAWAAEMCGEYAPDLNIVGAVLGSPVGDLGN
MAV_3194|M.avium_104 GLSPSAPIGLWGYSGGGLASAWAAETCAEYAPELNVVGAVLGSPVGDLGN
MSMEG_3197|M.smegmatis_MC2_155 PLTDASPIGLWGYSGGGLASGWAAEMSGSYAPELNIVGAVLGSPVGDLGH
Mflv_3621|M.gilvum_PYR-GCK GLAEDAPVGLWGYSGGGLASAWAAEVHDSYAPELNVVGAVLGSPVGDLGH
Mvan_2796|M.vanbaalenii_PYR-1 GLSPDAPVGLWGYSGGGLASAWAAEVQDAYAPELNVVGAVLGSPVGDLGH
TH_2810|M.thermoresistible__bu NLAVDAPVGLWGYSGGGLASAWAAEVCRDYAPDLNVVGAVLGSPVGDLGS
MAB_4134|M.abscessus_ATCC_1997 GLDQSTPVGIWGYSGGGMASSWAAEMAPAYAPEIGIVGAVLGAPVSDPGQ
* :*:*:*******:**.**** ***::.:******:**.* *
Mb1618c|M.bovis_AF2122/97 TFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEM
Rv1592c|M.tuberculosis_H37Rv TFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEM
MMAR_2389|M.marinum_M TFRRLNGTLLAGLPAMVVAALGHAYPGLDRVIKQHANEDGIELLERLEQM
MUL_1566|M.ulcerans_Agy99 TFRRLNGTLLAGLPAMVVAALGHAYPGLDRVIKQHANEDGIELLERLEQM
MAV_3194|M.avium_104 TFRRLNGSFLSGLPALVVAALAHIYPDLDRVIKEHANEEGRALLDSLEKM
MSMEG_3197|M.smegmatis_MC2_155 TFRRLNGTVFSGLPALVVAALADIYPGLNRVIAEHATTEGRKLLQRLHKM
Mflv_3621|M.gilvum_PYR-GCK AFRRLNGSIYSGLPAMVVAALTHVYPDLNRIIQQHATVEGKAMLARIEKM
Mvan_2796|M.vanbaalenii_PYR-1 TFRRLNGSIYAGLPALVVAALTHIYPDLHRVIQEHATEDGKVMLARIEKM
TH_2810|M.thermoresistible__bu AFRRLNGSLYAGLPAMVVAALAHIFPEVDQIIDEHATETGKAMLQRVEKM
MAB_4134|M.abscessus_ATCC_1997 LAVRLNATAFSGLTAIGIASLRRCYAGLDARINAHIDAEGQQILAAASQL
***.: :**.*: :*:* :. : * * * :* ::
Mb1618c|M.bovis_AF2122/97 TTVDAVIRMAGRDMGDFLDEPLEDILSTPEVSHVFGDTKLGSAVPTPPVL
Rv1592c|M.tuberculosis_H37Rv TTVDAVIRMAGRDMGDFLDEPLEDILSTPEISHVFGDTKLGSAVPTPPVL
MMAR_2389|M.marinum_M TTAEAVIRMANNDLGHYLDEPLDDVLSTPEVVHVFDDIKLGAAVPAPPVL
MUL_1566|M.ulcerans_Agy99 TTAEAVIRMANNDLGHYLDEPLEDVLSTPEVVHVFDDIKLGAAVPAPPVL
MAV_3194|M.avium_104 TTVEAVIRMAGKNMGDYLDAPLEQILSTPEVTYVFDHIRLGAAVPTPPVL
MSMEG_3197|M.smegmatis_MC2_155 STIEAVLRLARKDMDDLVDLPLEQILDSPEVTEVFDDIKLGVATPNPPVL
Mflv_3621|M.gilvum_PYR-GCK TTAHAMLSLVGKDMAHWVDRPLEEILLTPEVQHVFDSIKLGTSAPKVPVL
Mvan_2796|M.vanbaalenii_PYR-1 TTAHAMISLVGRDMAHMIDRPLEEILLSPEVQHVFDSIKLGTAAPKVPLL
TH_2810|M.thermoresistible__bu TTAHAVLRMIGMDMGKLVDQPLEEILQTPAMQRVFDRIKLGSAIPAPPVL
MAB_4134|M.abscessus_ATCC_1997 DTVRAGARFAKQDFNNHCDISLAELLTQPEIVEVFDDVRLGQHVPACPML
* * : :: . * .* ::* * : **. :** * *:*
Mb1618c|M.bovis_AF2122/97 IVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPLSAPMT
Rv1592c|M.tuberculosis_H37Rv IVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPLSAPMT
MMAR_2389|M.marinum_M IVQAVHDYLISVDDIDTLAESYSTGGARVTYHRDAFNEHMMLHPLSAPMT
MUL_1566|M.ulcerans_Agy99 IVQAVHDYLISVDDIDTLAESYSTGGARVTYHRDAFNEHMMLHPLSAPMT
MAV_3194|M.avium_104 IVQAVHDYLIDVHDIDVLADAYSAGGAQVTYHRDAFNEHMMLHPLSAPMT
MSMEG_3197|M.smegmatis_MC2_155 LIQAVHDELISVSSIDELAEKYLTGGASVTYHRDLFSEHLLLHPMSAPMA
Mflv_3621|M.gilvum_PYR-GCK IVQAVHDRIISVDDIDELTETYTAGGASVTYHRDMFSEHLLLHPMSAPMT
Mvan_2796|M.vanbaalenii_PYR-1 IVQAVHDRIISVDDIDALTETYTSGGASVTYHRDMLSEHLLLHPMSAPMT
TH_2810|M.thermoresistible__bu LVQACHDRIVSVDDIDTLADTYIEGGVRVTYHRDMFSEHMLLHPMSAPMT
MAB_4134|M.abscessus_ATCC_1997 VIHPQHDQIIDVRDVDAQVQRYLAADGHVSYVRDHCSEHISLMLLSAPLA
:::. ** ::.* .:* .: * .. *:* ** .**: * :***::
Mb1618c|M.bovis_AF2122/97 LRWLTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKL
Rv1592c|M.tuberculosis_H37Rv LRWLTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKL
MMAR_2389|M.marinum_M LRWLTDRFAGLPLTEHVIRTTWPTMFNPMTYAGMARLAVIAAKMITGRKI
MUL_1566|M.ulcerans_Agy99 LRWLTDRFAGLPLTEHVIRTTWPTMFNPMTYAGMARLAVTAAKMITGRKI
MAV_3194|M.avium_104 LRWLTDRFEGRPVTEHLIRTTWPTMFNPMTYVGMARLLKIAAKVVTGRKI
MSMEG_3197|M.smegmatis_MC2_155 LRWLTDRFAARPLTANLVRSKWPTLLNPVTYVGMARLAGIAAKVVTGRAL
Mflv_3621|M.gilvum_PYR-GCK LRWLRDRFAGRPISAHIARTKWPTLLNPSTYRGMLTLGKITAKVVLGRRV
Mvan_2796|M.vanbaalenii_PYR-1 LRWLRDRFAGRPLRTHISRTKWPTLLNPSTYRGMLTLGKITAKVMLGRRV
TH_2810|M.thermoresistible__bu LRWLRDRFAGQPLKHNLTRTKWPTMFNPSTYRGMLRLGLITAKVLTGRRV
MAB_4134|M.abscessus_ATCC_1997 LNWLKNRFRGTGTSNAQNIPVFSIALSAKAIRGYLSILATMLRAVLARPL
*.** :** . . :. :.. : * : : : .* :
Mb1618c|M.bovis_AF2122/97 SRRPL---------------------------------------------
Rv1592c|M.tuberculosis_H37Rv SRRPL---------------------------------------------
MMAR_2389|M.marinum_M HRRPL---------------------------------------------
MUL_1566|M.ulcerans_Agy99 HRRPL---------------------------------------------
MAV_3194|M.avium_104 HRRPL---------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 RRSPL---------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK ERQP----------------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 ERQP----------------------------------------------
TH_2810|M.thermoresistible__bu DRRPXXXRLHAEMIAELRWPGDPDPDSGIDIWAMELDPGQLAVLDILRRP
MAB_4134|M.abscessus_ATCC_1997 GPTTARSQHRI---------------------------------------
.
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK -----LSQFDL---------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 -----LSRFDQ---------------------------------------
TH_2810|M.thermoresistible__bu DVMTALTEWDAGDALGDYTRERIRSSSALAVVTVEGREPADYLRGGSALE
MAB_4134|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2810|M.thermoresistible__bu AVWIRAQQRGLAVHPVSPLFLYAHEEDELRALSPRFASSLVNLRREFHDL
MAB_4134|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1618c|M.bovis_AF2122/97 -----------------------------------
Rv1592c|M.tuberculosis_H37Rv -----------------------------------
MMAR_2389|M.marinum_M -----------------------------------
MUL_1566|M.ulcerans_Agy99 -----------------------------------
MAV_3194|M.avium_104 -----------------------------------
MSMEG_3197|M.smegmatis_MC2_155 -----------------------------------
Mflv_3621|M.gilvum_PYR-GCK -----------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 -----------------------------------
TH_2810|M.thermoresistible__bu AGTRRGESQIIVFRLFEAPPASVRSRRRSGGIGVD
MAB_4134|M.abscessus_ATCC_1997 -----------------------------------