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PSMTIGKYCAQAKARTVAIDCDRRRWRAAIRSVAVLLVSLALTPFFAPGAARADESRYWQFYTPPEPLPA GALGDLIRTEPSRLALEPSGQLGSYVGTGTRIMYRSTDNNGKPVAATGTYIEPDNPWPGDGPRPLLVYAP LPNGMGEQCAASRLINQGIHASGDTGFDLMVNLDSMFLTTLLARGYSIVIPDGIGSGVHGRMAPQLLMRI ASATAVIDAARAAKKLPGTSLTPDGPVAFWGWFSGGSAALAAAELASTYGPELKIAGTVAMEPVTDMASV ASSADGSFLVGAMGWLLNAIVATYPEFDQPLREMLTPRGLEMFENTAGQCMLQTGTDYAFRHVQPWFKND ILQAVRQEPFKSLSDAQRIGNHKPTGPVYIEHNRWDPVGPYADAMATAKDWCAMGADVTFWTNELPPLFN KLGTNLFLAPLVDGERNMAWLADRFNGVPTSSNCSELP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0918c | - | - | 100% (459) | triacylglycerol lipase |
| M. abscessus ATCC 19977 | MAB_4351 | - | e-150 | 60.65% (432) | secretory lipase family protein |
| M. abscessus ATCC 19977 | MAB_2676 | - | 7e-29 | 26.72% (393) | hypothetical protein MAB_2676 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1618c | - | 1e-28 | 26.14% (394) | hypothetical protein Mb1618c |
| M. gilvum PYR-GCK | Mflv_3621 | - | 9e-28 | 25.13% (394) | triacylglycerol lipase |
| M. tuberculosis H37Rv | Rv1592c | - | 8e-29 | 26.14% (394) | hypothetical protein Rv1592c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1029 | - | 1e-131 | 52.04% (442) | lipase |
| M. avium 104 | MAV_5251 | - | 1e-129 | 53.79% (435) | secretory lipase family protein |
| M. smegmatis MC2 155 | MSMEG_3197 | - | 9e-25 | 24.87% (394) | lipase |
| M. thermoresistible (build 8) | TH_3043 | - | 1e-130 | 55.37% (428) | PUTATIVE Triacylglycerol lipase |
| M. ulcerans Agy99 | MUL_0787 | - | 1e-131 | 52.26% (442) | lipase |
| M. vanbaalenii PYR-1 | Mvan_2796 | - | 2e-30 | 27.79% (403) | triacylglycerol lipase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5251|M.avium_104 ---------------MRDCY-RSVMRRVAGVFAALVLMAGTLTGPAIARA
TH_3043|M.thermoresistible__bu -----------------------MVRGFAGSVCVLLIVSMGMSSP-LARA
MMAR_1029|M.marinum_M ---------------MRAARGRLQSRLQVVVVAMLSCATITVVAPDSARA
MUL_0787|M.ulcerans_Agy99 ---MVIEKRDLFVRGMRAARGRLQSRLQVVVVAMLSCATITVVAPDSARA
MAB_0918c|M.abscessus_ATCC_199 MPSMTIGKYCAQAKARTVAIDCDRRRWRAAIRSVAVLLVSLALTPFFAPG
Mb1618c|M.bovis_AF2122/97 ----------------------MVEPGNLAGATGAEWIGRPPHEELQRKV
Rv1592c|M.tuberculosis_H37Rv ----------------------MVEPGNLAGATGAEWIGRPPHEELQRKV
MSMEG_3197|M.smegmatis_MC2_155 -----------------------MDLSSAAKAADAEWIGRAPHEELDRDA
Mflv_3621|M.gilvum_PYR-GCK -----------------------MDLGNVARSTGAEWIGQPRHEELRPRT
Mvan_2796|M.vanbaalenii_PYR-1 -----------------------MDLGNVARSTGAEWIGQPFHEPLRPRS
MAV_5251|M.avium_104 DG------DEPQYADFYTPPDPLPPGRPGDLIRTEPSRLVLEPSGQLGAI
TH_3043|M.thermoresistible__bu EDPFT---HEQKYTAFYTPPDPLPPGEPGDLIRTEPARLVLEPSGQLGAI
MMAR_1029|M.marinum_M DGGFESEGDQSQYDQFYTPPDPLPPGEPGDVIRTEPSRLVLEPSGQLGAI
MUL_0787|M.ulcerans_Agy99 DGGFESEGDQSQYDQFYTPPDPLPPGEPGDVIRTEPSRLALEPSGQLGAI
MAB_0918c|M.abscessus_ATCC_199 AAR----ADESRYWQFYTPPEPLPAGALGDLIRTEPSRLALEPSGQLGSY
Mb1618c|M.bovis_AF2122/97 RP------LLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMG---LIPQ
Rv1592c|M.tuberculosis_H37Rv RP------LLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMG---LIPQ
MSMEG_3197|M.smegmatis_MC2_155 RP------GLPGEDPFYLPPAGYHHAEPGTVLRSRDVELAFLG---LVPQ
Mflv_3621|M.gilvum_PYR-GCK RP------VIPADDPFYEPPEGYEHARPGTVLRSRDVELAFLG---LIPQ
Mvan_2796|M.vanbaalenii_PYR-1 RP------MIPAKDDFYEPPAGFEHARPGTVLRSRDVELAFLG---VIPQ
** ** . * ::*:. .*.: : .
MAV_5251|M.avium_104 MATGTRIMYRSTDTRGNPIAVTGTYFEPYNDWPYGGPRPLISYAPGTQGQ
TH_3043|M.thermoresistible__bu MATGTRIMYRSTDSRGNPNVVTGMYFEPHNDWPHGGPRPLIAYGPGTQGQ
MMAR_1029|M.marinum_M MATGTRIMYRSTDTRGNPIAVTGTYFEPDNPWPGSGPRPLLSYAPGTVGQ
MUL_0787|M.ulcerans_Agy99 MATGTRIMYRSTDTRGNPIAVTGTYFEPDNPWPGSGPRPLLRYAPGTVGQ
MAB_0918c|M.abscessus_ATCC_199 VGTGTRIMYRSTDNNGKPVAATGTYIEPDNPWPGDGPRPLLVYAPLPNGM
Mb1618c|M.bovis_AF2122/97 PVTATQLLYRTTNMYGNPEATVTTVIVP-AELAPGQTCPLLSYQCAIDAM
Rv1592c|M.tuberculosis_H37Rv PVTATQLLYRTTNMYGNPEATVTTVIVP-AELAPGQTCPLLSYQCAIDAM
MSMEG_3197|M.smegmatis_MC2_155 ALHATQLLYRTTDRNGAPEAAVTTVIMP-PDARAG--CPIVSYQCAIDAI
Mflv_3621|M.gilvum_PYR-GCK KFSATQLLYRTTDLYGQPQATVTTVLAP-TERTDRRPLPIVSYQCAIDAV
Mvan_2796|M.vanbaalenii_PYR-1 KFTATQLLYRTTDLNGEAQATVTTVVVP-SERTSDGPLPIVSYQCAIDAV
.*:::**:*: * . ... . * *:: * .
MAV_5251|M.avium_104 GNQCAPSRMFNQGIHYS--GGWDIMFNYEELFVATMVARGFAIVMTDYQG
TH_3043|M.thermoresistible__bu GDQCAPSRMFSEGIHWT--SGADIMFNYEEMFVATMVARGFAIVMTDYEG
MMAR_1029|M.marinum_M GDQCALSRVFNQGIHWS--PWLDLMVNYEETFVATMVARGFAIVMTDYEG
MUL_0787|M.ulcerans_Agy99 GDQCALSRVFNQGIHWS--PWLDLMVNYEETFVATMVARGFAIVMTDYEG
MAB_0918c|M.abscessus_ATCC_199 GEQCAASRLINQGIHASGDTGFDLMVNLDSMFLTTLLARGYSIVIPDGIG
Mb1618c|M.bovis_AF2122/97 SSRCFPSYALRRRAKALG-----SLTQMELLMISAALAEGWAVSVPDHEG
Rv1592c|M.tuberculosis_H37Rv SSRCFPSYALRRRAKALG-----SLTQMELLMISAALAEGWAVSVPDHEG
MSMEG_3197|M.smegmatis_MC2_155 SATCFPSYALRRHAKVTG-----GLAQFELLLITAALAEGWAVSVPDHEG
Mflv_3621|M.gilvum_PYR-GCK AGRCFPSYALRRGAKALG-----AVAQFEFLLIAAALAEGWAVSVPDHEG
Mvan_2796|M.vanbaalenii_PYR-1 AGRCFPSYALRRGAKALG-----SFAQFEFLLVAAALAEGWAVSVPDHEG
. * * : . : . : : :::: :*.*::: :.* *
MAV_5251|M.avium_104 LGTPP--MHTYVGRVAEGQAVLDAARAAMRLPGTSLDPHGPVAFWGYSQG
TH_3043|M.thermoresistible__bu LGTPG--VHTYVNRLAQGHALIDAARAAKRLPGTSLDPDGPVAFWGYSQG
MMAR_1029|M.marinum_M LGTPG--THTYVNRLAEGHAVLDAARAAQRLPGTSLDPHGPVAFWGYSQG
MUL_0787|M.ulcerans_Agy99 LGTPG--THTYVNRLAEGHAVLDAARAAQRLPGTSLDPHGPVAFWGYSQG
MAB_0918c|M.abscessus_ATCC_199 SGVHGRMAPQLLMRIASATAVIDAARAAKKLPGTSLTPDGPVAFWGWFSG
Mb1618c|M.bovis_AF2122/97 P------KGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGG
Rv1592c|M.tuberculosis_H37Rv P------KGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGG
MSMEG_3197|M.smegmatis_MC2_155 L------DGMWGAPYEPGYHVLDGLRAALNSERLPLTDASPIGLWGYSGG
Mflv_3621|M.gilvum_PYR-GCK T------TGMWGAPFEPGYHVLDGIRAAVNHRPLGLAEDAPVGLWGYSGG
Mvan_2796|M.vanbaalenii_PYR-1 T------SGMWGAPHEPGYHVLDGVRAALNHGPLGLSPDAPVGLWGYSGG
. ::*. *** . * *:.:**: *
MAV_5251|M.avium_104 GGATASAAELAAQYAPDLHIVGTYAGAPPADLKELLPYADGSALVGVVGY
TH_3043|M.thermoresistible__bu GGAAASAAELASTYGPELDVVGTYAGSPPADLVALLPFADGSVLVGALGY
MMAR_1029|M.marinum_M GGAAASAAELVSSYAPELDVVGTYAGAPPADLVEMLPYMDGNVLVGAAGY
MUL_0787|M.ulcerans_Agy99 GGAAASAAELVSSYAPELDVVGTYAGAPPADLVEMLPYMDGNVLVGAAGC
MAB_0918c|M.abscessus_ATCC_199 GSAALAAAELASTYGPELKIAGTVAMEPVTDMASVASSADGSFLVGAMGW
Mb1618c|M.bovis_AF2122/97 GLASAWAAEACGEYAPDLDIVGAVLGSPVGDLGHTFRRLNGTLLAGLPAL
Rv1592c|M.tuberculosis_H37Rv GLASAWAAEACGEYAPDLDIVGAVLGSPVGDLGHTFRRLNGTLLAGLPAL
MSMEG_3197|M.smegmatis_MC2_155 GLASGWAAEMSGSYAPELNIVGAVLGSPVGDLGHTFRRLNGTVFSGLPAL
Mflv_3621|M.gilvum_PYR-GCK GLASAWAAEVHDSYAPELNVVGAVLGSPVGDLGHAFRRLNGSIYSGLPAM
Mvan_2796|M.vanbaalenii_PYR-1 GLASAWAAEVQDAYAPELNVVGAVLGSPVGDLGHTFRRLNGSIYAGLPAL
* *: *** *.*:*.:.*: * *: :*. * .
MAV_5251|M.avium_104 ALNSVMAAYPEFADAIRSKMTPRGLAMLESVSRQCVGQTLLDFMFRHIQP
TH_3043|M.thermoresistible__bu ALNGAIAAYPEAEEKIRATLTPRGAHMLDEVKDQCVGETLMKFAFRHLQP
MMAR_1029|M.marinum_M LINGFIYAYPELADAIHERMTPRGEDLLAKTRHQCVQETSFKFMFRHLRG
MUL_0787|M.ulcerans_Agy99 LINGFIYAYPELADAIHERMTPRGEDLLAKTRHQCVEETSFKFMFRHLRG
MAB_0918c|M.abscessus_ATCC_199 LLNAIVATYPEFDQPLREMLTPRGLEMFENTAGQCMLQTGTDYAFRHVQP
Mb1618c|M.bovis_AF2122/97 VVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGD
Rv1592c|M.tuberculosis_H37Rv VVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGD
MSMEG_3197|M.smegmatis_MC2_155 VVAALADIYPGLNRVIAEHATTEGRKLLQRLHKMSTIEAVLRLARKDMDD
Mflv_3621|M.gilvum_PYR-GCK VVAALTHVYPDLNRIIQQHATVEGKAMLARIEKMTTAHAMLSLVGKDMAH
Mvan_2796|M.vanbaalenii_PYR-1 VVAALTHIYPDLHRVIQEHATEDGKVMLARIEKMTTAHAMISLVGRDMAH
: . ** : . * :: .: :.:
MAV_5251|M.avium_104 YFTEDINQLVNEEPFNSLFEAQRIGRYKPNAPVLINSNRYDPLVPWTAAN
TH_3043|M.thermoresistible__bu YFNVDIFTAVEEEPFKSLFELQRLGGLKPEGPVLINANRFDPLVPWAPAM
MMAR_1029|M.marinum_M YFTKDLDQLVREEPFKTLFEAQRLGRHQPSAPVLIVNNRYDPLVPWTQAS
MUL_0787|M.ulcerans_Agy99 YFTKDLDQLVREEPFKTLFEAQRLGRHQPSAPVLIVNNRYDPLVPWTQAS
MAB_0918c|M.abscessus_ATCC_199 WFKNDILQAVRQEPFKSLSDAQRIGNHKPTGPVYIEHNRWDPVGPYADAM
Mb1618c|M.bovis_AF2122/97 FLDEPLEDILSTPEVSHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDID
Rv1592c|M.tuberculosis_H37Rv FLDEPLEDILSTPEISHVFGDTKLGSAVPTPPVLIVQAVHDYLIDVSDID
MSMEG_3197|M.smegmatis_MC2_155 LVDLPLEQILDSPEVTEVFDDIKLGVATPNPPVLLIQAVHDELISVSSID
Mflv_3621|M.gilvum_PYR-GCK WVDRPLEEILLTPEVQHVFDSIKLGTSAPKVPVLIVQAVHDRIISVDDID
Mvan_2796|M.vanbaalenii_PYR-1 MIDRPLEEILLSPEVQHVFDSIKLGTAAPKVPLLIVQAVHDRIISVDDID
. : : . : ::* * *: : * :
MAV_5251|M.avium_104 QLGRDWCAQGADVEFRTNEEPPFLNKLVINHALPMLVDGEPAMQWIAARF
TH_3043|M.thermoresistible__bu QMGRDWCAMGADVEARTNEQPPLFNKLIVNHGLPMLVDGEPAMQWIADRF
MMAR_1029|M.marinum_M QLGRDWCAQGAQVEFWTNEEPPFLNKASVNHALTFWVDGERALQWVADRF
MUL_0787|M.ulcerans_Agy99 QLGRDWCAQGAQVEFWTNEEPPFLNKASVNHALTFWVDGERALQWVADRF
MAB_0918c|M.abscessus_ATCC_199 ATAKDWCAMGADVTFWTNELPPLFNKLGTNLFLAPLVDGERNMAWLADRF
Mb1618c|M.bovis_AF2122/97 ALADSYTAGGANVTYHR--------DLFSEHVSLHPLSAPMTLRWLTDRF
Rv1592c|M.tuberculosis_H37Rv ALADSYTAGGANVTYHR--------DLFSEHVSLHPLSAPMTLRWLTDRF
MSMEG_3197|M.smegmatis_MC2_155 ELAEKYLTGGASVTYHR--------DLFSEHLLLHPMSAPMALRWLTDRF
Mflv_3621|M.gilvum_PYR-GCK ELTETYTAGGASVTYHR--------DMFSEHLLLHPMSAPMTLRWLRDRF
Mvan_2796|M.vanbaalenii_PYR-1 ALTETYTSGGASVTYHR--------DMLSEHLLLHPMSAPMTLRWLRDRF
: : **.* . : :.. : *: **
MAV_5251|M.avium_104 RGEPTAPNCGQF--------------------------------------
TH_3043|M.thermoresistible__bu KGVPTAPNCGRF--------------------------------------
MMAR_1029|M.marinum_M NGLPAAPNCGQF--------------------------------------
MUL_0787|M.ulcerans_Agy99 NGRPAAPNCGQF--------------------------------------
MAB_0918c|M.abscessus_ATCC_199 NGVPTSSNCSELP-------------------------------------
Mb1618c|M.bovis_AF2122/97 AGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL---
Rv1592c|M.tuberculosis_H37Rv AGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL---
MSMEG_3197|M.smegmatis_MC2_155 AARPLTANLVRSKWPTLLNPVTYVGMARLAGIAAKVVTGRALRRSPL---
Mflv_3621|M.gilvum_PYR-GCK AGRPISAHIARTKWPTLLNPSTYRGMLTLGKITAKVVLGRRVERQPLSQF
Mvan_2796|M.vanbaalenii_PYR-1 AGRPLRTHISRTKWPTLLNPSTYRGMLTLGKITAKVMLGRRVERQPLSRF
. * : .
MAV_5251|M.avium_104 --
TH_3043|M.thermoresistible__bu --
MMAR_1029|M.marinum_M --
MUL_0787|M.ulcerans_Agy99 --
MAB_0918c|M.abscessus_ATCC_199 --
Mb1618c|M.bovis_AF2122/97 --
Rv1592c|M.tuberculosis_H37Rv --
MSMEG_3197|M.smegmatis_MC2_155 --
Mflv_3621|M.gilvum_PYR-GCK DL
Mvan_2796|M.vanbaalenii_PYR-1 DQ