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DLGNVARSTGAEWIGQPFHEPLRPRSRPMIPAKDDFYEPPAGFEHARPGTVLRSRDVELAFLGVIPQKFT ATQLLYRTTDLNGEAQATVTTVVVPSERTSDGPLPIVSYQCAIDAVAGRCFPSYALRRGAKALGSFAQFE FLLVAAALAEGWAVSVPDHEGTSGMWGAPHEPGYHVLDGVRAALNHGPLGLSPDAPVGLWGYSGGGLASA WAAEVQDAYAPELNVVGAVLGSPVGDLGHTFRRLNGSIYAGLPALVVAALTHIYPDLHRVIQEHATEDGK VMLARIEKMTTAHAMISLVGRDMAHMIDRPLEEILLSPEVQHVFDSIKLGTAAPKVPLLIVQAVHDRIIS VDDIDALTETYTSGGASVTYHRDMLSEHLLLHPMSAPMTLRWLRDRFAGRPLRTHISRTKWPTLLNPSTY RGMLTLGKITAKVMLGRRVERQPLSRFDQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2796 | - | - | 100% (450) | triacylglycerol lipase |
| M. vanbaalenii PYR-1 | Mvan_2478 | - | 4e-05 | 23.03% (343) | secretory lipase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1618c | - | 1e-177 | 66.06% (442) | hypothetical protein Mb1618c |
| M. gilvum PYR-GCK | Mflv_3621 | - | 0.0 | 87.31% (449) | triacylglycerol lipase |
| M. tuberculosis H37Rv | Rv1592c | - | 1e-177 | 65.84% (442) | hypothetical protein Rv1592c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2676 | - | 1e-166 | 64.52% (434) | hypothetical protein MAB_2676 |
| M. marinum M | MMAR_2389 | - | 1e-177 | 65.24% (443) | hypothetical protein MMAR_2389 |
| M. avium 104 | MAV_3194 | - | 1e-180 | 66.89% (444) | secretory lipase family protein |
| M. smegmatis MC2 155 | MSMEG_3197 | - | 1e-173 | 65.84% (445) | lipase |
| M. thermoresistible (build 8) | TH_2810 | - | 0.0 | 73.65% (444) | PUTATIVE Triacylglycerol lipase |
| M. ulcerans Agy99 | MUL_1566 | - | 1e-176 | 64.79% (443) | hypothetical protein MUL_1566 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2796|M.vanbaalenii_PYR-1 -----------MDLGNVARSTGAEWIGQPFHEPLRPRSRPMIPAKDDFYE
Mflv_3621|M.gilvum_PYR-GCK -----------MDLGNVARSTGAEWIGQPRHEELRPRTRPVIPADDPFYE
TH_2810|M.thermoresistible__bu -----------MDLGSAAQSTGAEWIGRPTHEALR-RTRPILPERDPFYE
Mb1618c|M.bovis_AF2122/97 ----------MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYF
Rv1592c|M.tuberculosis_H37Rv ----------MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYF
MMAR_2389|M.marinum_M -MPKAMKGALMVKLGSLADARAAEWIGRPPHEELQRKVRPLLPSDDPFYD
MUL_1566|M.ulcerans_Agy99 ----------MVKLGSLADARAAGWIGRPPHEELQRKVRPLLPSDDPFYD
MAV_3194|M.avium_104 ----------MAELGNLAGTHGAEWIARPPHEELQRKVRPLLPSDDPFYQ
MSMEG_3197|M.smegmatis_MC2_155 -----------MDLSSAAKAADAEWIGRAPHEELDRDARPGLPGEDPFYL
MAB_2676|M.abscessus_ATCC_1997 MNARDLEGSAGMASHDLAISADVKWIGEAPHQNVERGAPTLLPTEDPFYL
. * : . **... *: : . :* * **
Mvan_2796|M.vanbaalenii_PYR-1 PPAGFEHARPGTVLRSRDVELAFLGVIPQKFTATQLLYRTTDLNGEAQAT
Mflv_3621|M.gilvum_PYR-GCK PPEGYEHARPGTVLRSRDVELAFLGLIPQKFSATQLLYRTTDLYGQPQAT
TH_2810|M.thermoresistible__bu PPPGFEHARPGTVLRSRDVELAFMGLIPQKFTATQLLYRTTGFDGRPRAT
Mb1618c|M.bovis_AF2122/97 PPAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRTTNMYGNPEAT
Rv1592c|M.tuberculosis_H37Rv PPAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRTTNMYGNPEAT
MMAR_2389|M.marinum_M PPAGYHHAEPGTVLRSREVELAFLGLIPQSITATQLLYRTTDMYGNPEAT
MUL_1566|M.ulcerans_Agy99 PPAGYHHAEPGTVLRSREVELAFLGLIPQSITATQLLYRTTDMYGNPEAT
MAV_3194|M.avium_104 PPLGFQHAEPGTVLRSRDVELAFLGLIPQPIKAVQLLYRTMDMNGEPEAT
MSMEG_3197|M.smegmatis_MC2_155 PPAGYHHAEPGTVLRSRDVELAFLGLVPQALHATQLLYRTTDRNGAPEAA
MAB_2676|M.abscessus_ATCC_1997 PPLGYEHAAPGTVLRSRDVEMAFLGVIPQRFTATQLLYRSNDLNRRADAA
** *:.** ********:**:**:*::** . *.*****: . . *:
Mvan_2796|M.vanbaalenii_PYR-1 VTTVVVPSERTSDGPLPIVSYQCAIDAVAGRCFPSYALRRGAKALGSFAQ
Mflv_3621|M.gilvum_PYR-GCK VTTVLAPTERTDRRPLPIVSYQCAIDAVAGRCFPSYALRRGAKALGAVAQ
TH_2810|M.thermoresistible__bu VTTVVVPAERDKNGRCPVVSYQCAIDAVTSRCFPSYALRRGARAVGALAQ
Mb1618c|M.bovis_AF2122/97 VTTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQ
Rv1592c|M.tuberculosis_H37Rv VTTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQ
MMAR_2389|M.marinum_M VTTVILPAEVAPGQTYPLLSYQCAIDAMSSRCFPSYALRRGAKAIGSLTQ
MUL_1566|M.ulcerans_Agy99 VTTVILPAEVAPGQTYPLLSYQCAIDAMSSRCFPSYALRRGAKAIGSLTQ
MAV_3194|M.avium_104 VTTVIVPADAVPGRPCPLLSYQCAIDAVSSRCFPSYALRRRAKALGSIGQ
MSMEG_3197|M.smegmatis_MC2_155 VTTVIMPPDARAG--CPIVSYQCAIDAISATCFPSYALRRHAKVTGGLAQ
MAB_2676|M.abscessus_ATCC_1997 VTTVLIPDHDDPATPVPIVSYQCAIDAVTDRCFPSYALRRGAQALGSFTQ
****: * . *::********:: ********* *:. *.. *
Mvan_2796|M.vanbaalenii_PYR-1 FEFLLVAAALAEGWAVSVPDHEGTSGMWGAPHEPGYHVLDGVRAALNHGP
Mflv_3621|M.gilvum_PYR-GCK FEFLLIAAALAEGWAVSVPDHEGTTGMWGAPFEPGYHVLDGIRAAVNHRP
TH_2810|M.thermoresistible__bu FEFLLIAAALAEGWAVSVPDHEGPDGSWGAPLEPGYHILDGLRAALGYER
Mb1618c|M.bovis_AF2122/97 MELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLDGIRAALNSER
Rv1592c|M.tuberculosis_H37Rv MELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLDGIRAALNSER
MMAR_2389|M.marinum_M LELLLITAAVAEGWAVSVPDHEGVRGLWGTPYEPGYRVLDGIRAALSAER
MUL_1566|M.ulcerans_Agy99 LELLLITAAVAEGWAVSVPDHEGVRGLWGTPYEPGYRVLDGIRAALSAER
MAV_3194|M.avium_104 FELFLITAAVAEGWAVSVPDHEGLRGLWGAPYEPGYRVLDGIRAALGSER
MSMEG_3197|M.smegmatis_MC2_155 FELLLITAALAEGWAVSVPDHEGLDGMWGAPYEPGYHVLDGLRAALNSER
MAB_2676|M.abscessus_ATCC_1997 FELLLIAALLAQGWAVSIPDHEGVDGSWGAPDEPGYRTLDGIRAALNCDR
:*:::::* :*:*****:***** * **:* ****: ***:***:.
Mvan_2796|M.vanbaalenii_PYR-1 LGLSPDAPVGLWGYSGGGLASAWAAEVQDAYAPELNVVGAVLGSPVGDLG
Mflv_3621|M.gilvum_PYR-GCK LGLAEDAPVGLWGYSGGGLASAWAAEVHDSYAPELNVVGAVLGSPVGDLG
TH_2810|M.thermoresistible__bu LNLAVDAPVGLWGYSGGGLASAWAAEVCRDYAPDLNVVGAVLGSPVGDLG
Mb1618c|M.bovis_AF2122/97 VGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLG
Rv1592c|M.tuberculosis_H37Rv VGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPVGDLG
MMAR_2389|M.marinum_M LALPQSAPIGLWGYSGGGLASAWAAEMCGEYAPELNIVGAVLGSPVGDLG
MUL_1566|M.ulcerans_Agy99 LALPQSAPIGLWGYSGGGLASAWAAEMCGEYAPDLNIVGAVLGSPVGDLG
MAV_3194|M.avium_104 LGLSPSAPIGLWGYSGGGLASAWAAETCAEYAPELNVVGAVLGSPVGDLG
MSMEG_3197|M.smegmatis_MC2_155 LPLTDASPIGLWGYSGGGLASGWAAEMSGSYAPELNIVGAVLGSPVGDLG
MAB_2676|M.abscessus_ATCC_1997 LGLSRQAPIGLWGYSGGGLATAWAAEASADYAPELSITGAVLGSPVGDLG
: *. :*:***********:.**** ***:*.:.************
Mvan_2796|M.vanbaalenii_PYR-1 HTFRRLNGSIYAGLPALVVAALTHIYPDLHRVIQEHATEDGKVMLARIEK
Mflv_3621|M.gilvum_PYR-GCK HAFRRLNGSIYSGLPAMVVAALTHVYPDLNRIIQQHATVEGKAMLARIEK
TH_2810|M.thermoresistible__bu SAFRRLNGSLYAGLPAMVVAALAHIFPEVDQIIDEHATETGKAMLQRVEK
Mb1618c|M.bovis_AF2122/97 HTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTE
Rv1592c|M.tuberculosis_H37Rv HTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTE
MMAR_2389|M.marinum_M NTFRRLNGTLLAGLPAMVVAALGHAYPGLDRVIKQHANEDGIELLERLEQ
MUL_1566|M.ulcerans_Agy99 NTFRRLNGTLLAGLPAMVVAALGHAYPGLDRVIKQHANEDGIELLERLEQ
MAV_3194|M.avium_104 NTFRRLNGSFLSGLPALVVAALAHIYPDLDRVIKEHANEEGRALLDSLEK
MSMEG_3197|M.smegmatis_MC2_155 HTFRRLNGTVFSGLPALVVAALADIYPGLNRVIAEHATTEGRKLLQRLHK
MAB_2676|M.abscessus_ATCC_1997 HTFRRLNGGLFAALPGLVVAALSHVYPGLERVIEEHATTKGKEFLGRLED
:****** . :.**.:***** . :* : ::* :**. * :* : .
Mvan_2796|M.vanbaalenii_PYR-1 MTTAHAMISLVGRDMAHMIDRPLEEILLSPEVQHVFDSIKLGTAAPKVPL
Mflv_3621|M.gilvum_PYR-GCK MTTAHAMLSLVGKDMAHWVDRPLEEILLTPEVQHVFDSIKLGTSAPKVPV
TH_2810|M.thermoresistible__bu MTTAHAVLRMIGMDMGKLVDQPLEEILQTPAMQRVFDRIKLGSAIPAPPV
Mb1618c|M.bovis_AF2122/97 MTTVDAVIRMAGRDMGDFLDEPLEDILSTPEVSHVFGDTKLGSAVPTPPV
Rv1592c|M.tuberculosis_H37Rv MTTVDAVIRMAGRDMGDFLDEPLEDILSTPEISHVFGDTKLGSAVPTPPV
MMAR_2389|M.marinum_M MTTAEAVIRMANNDLGHYLDEPLDDVLSTPEVVHVFDDIKLGAAVPAPPV
MUL_1566|M.ulcerans_Agy99 MTTAEAVIRMANNDLGHYLDEPLEDVLSTPEVVHVFDDIKLGAAVPAPPV
MAV_3194|M.avium_104 MTTVEAVIRMAGKNMGDYLDAPLEQILSTPEVTYVFDHIRLGAAVPTPPV
MSMEG_3197|M.smegmatis_MC2_155 MSTIEAVLRLARKDMDDLVDLPLEQILDSPEVTEVFDDIKLGVATPNPPV
MAB_2676|M.abscessus_ATCC_1997 MPTFRAIIAMAFKDMDDLVDRPLEQLLQTPEVRHVFDSIKLGKTVPTPPV
*.* *:: : :: . :* **:::* :* : **. :** : * *:
Mvan_2796|M.vanbaalenii_PYR-1 LIVQAVHDRIISVDDIDALTETYTSGGASVTYHRDMLSEHLLLHPMSAPM
Mflv_3621|M.gilvum_PYR-GCK LIVQAVHDRIISVDDIDELTETYTAGGASVTYHRDMFSEHLLLHPMSAPM
TH_2810|M.thermoresistible__bu LLVQACHDRIVSVDDIDTLADTYIEGGVRVTYHRDMFSEHMLLHPMSAPM
Mb1618c|M.bovis_AF2122/97 LIVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPLSAPM
Rv1592c|M.tuberculosis_H37Rv LIVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPLSAPM
MMAR_2389|M.marinum_M LIVQAVHDYLISVDDIDTLAESYSTGGARVTYHRDAFNEHMMLHPLSAPM
MUL_1566|M.ulcerans_Agy99 LIVQAVHDYLISVDDIDTLAESYSTGGARVTYHRDAFNEHMMLHPLSAPM
MAV_3194|M.avium_104 LIVQAVHDYLIDVHDIDVLADAYSAGGAQVTYHRDAFNEHMMLHPLSAPM
MSMEG_3197|M.smegmatis_MC2_155 LLIQAVHDELISVSSIDELAEKYLTGGASVTYHRDLFSEHLLLHPMSAPM
MAB_2676|M.abscessus_ATCC_1997 LIVQAVHDEIISTSCIDELADTYRGGGADVAYHRDLLNEHILLHPMSAPM
*::** ** ::.. ** *:: * **. *:**** :.**: ***:****
Mvan_2796|M.vanbaalenii_PYR-1 TLRWLRDRFAGRPLRTHISRTKWPTLLNPSTYRGMLTLGKITAKVMLGRR
Mflv_3621|M.gilvum_PYR-GCK TLRWLRDRFAGRPISAHIARTKWPTLLNPSTYRGMLTLGKITAKVVLGRR
TH_2810|M.thermoresistible__bu TLRWLRDRFAGQPLKHNLTRTKWPTMFNPSTYRGMLRLGLITAKVLTGRR
Mb1618c|M.bovis_AF2122/97 TLRWLTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRK
Rv1592c|M.tuberculosis_H37Rv TLRWLTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRK
MMAR_2389|M.marinum_M TLRWLTDRFAGLPLTEHVIRTTWPTMFNPMTYAGMARLAVIAAKMITGRK
MUL_1566|M.ulcerans_Agy99 TLRWLTDRFAGLPLTEHVIRTTWPTMFNPMTYAGMARLAVTAAKMITGRK
MAV_3194|M.avium_104 TLRWLTDRFEGRPVTEHLIRTTWPTMFNPMTYVGMARLLKIAAKVVTGRK
MSMEG_3197|M.smegmatis_MC2_155 ALRWLTDRFAARPLTANLVRSKWPTLLNPVTYVGMARLAGIAAKVVTGRA
MAB_2676|M.abscessus_ATCC_1997 SMEWLSARFRGEPLPTGPRRTSWPLAFKPSTYLGLLKLGWIGAKVLGGRS
::.** ** . *: *:.** ::* ** *: * **:: **
Mvan_2796|M.vanbaalenii_PYR-1 VERQP---------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK VERQP---------------------------------------------
TH_2810|M.thermoresistible__bu VDRRPXXXRLHAEMIAELRWPGDPDPDSGIDIWAMELDPGQLAVLDILRR
Mb1618c|M.bovis_AF2122/97 LSRRPL--------------------------------------------
Rv1592c|M.tuberculosis_H37Rv LSRRPL--------------------------------------------
MMAR_2389|M.marinum_M IHRRPL--------------------------------------------
MUL_1566|M.ulcerans_Agy99 IHRRPL--------------------------------------------
MAV_3194|M.avium_104 IHRRPL--------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 LRRSPL--------------------------------------------
MAB_2676|M.abscessus_ATCC_1997 L-------------------------------------------------
:
Mvan_2796|M.vanbaalenii_PYR-1 ------LSRFDQ--------------------------------------
Mflv_3621|M.gilvum_PYR-GCK ------LSQFDL--------------------------------------
TH_2810|M.thermoresistible__bu PDVMTALTEWDAGDALGDYTRERIRSSSALAVVTVEGREPADYLRGGSAL
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2676|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK --------------------------------------------------
TH_2810|M.thermoresistible__bu EAVWIRAQQRGLAVHPVSPLFLYAHEEDELRALSPRFASSLVNLRREFHD
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2676|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 ------------------------------------
Mflv_3621|M.gilvum_PYR-GCK ------------------------------------
TH_2810|M.thermoresistible__bu LAGTRRGESQIIVFRLFEAPPASVRSRRRSGGIGVD
Mb1618c|M.bovis_AF2122/97 ------------------------------------
Rv1592c|M.tuberculosis_H37Rv ------------------------------------
MMAR_2389|M.marinum_M ------------------------------------
MUL_1566|M.ulcerans_Agy99 ------------------------------------
MAV_3194|M.avium_104 ------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 ------------------------------------
MAB_2676|M.abscessus_ATCC_1997 ------------------------------------