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VTVEMDAPTTETGLADIAIVGMQCRFAGADDVDKYWSLLSEKREGARSLDGLAAAPGWVRREAAIDGIEL FDATFFGYPPAEAAMIDPQHRLFLECAYHVFEQAGYDPDRYEGLVGVYAGSGQSSYLIANVLPHLGVSPS SADALPAGFANSPGSLPGRVSYHLNLTGPSIAVSTACSTSLVAVHLACQELLDYRCDLALAGGVSLNPHP GKGYRHTPNGPLSPDGRCRAFDAAAAGMFPGDGVGVVLLKRLSDALADGDRIRAVVKGSAVNNDGRHKTG FTAPSVTAQSEVIMAAHAVAGVEASSIGMVEAHGTGTPVGDPIEVAALTKAFRESTDRTGYCMLGSAKTN IGHTDTAAGVAGLIKAVLSIEHGVIPANLHYSAENPLLDLAGSPFRVAADTVDWPEGDGPRRAGVSAFGI GGTNAHVVLEQAPDHVEAESPGTDGGLESLLVLSAATPSALDQQAKQLADYVRSNSEVDPADVADTLQWG RRKLPYRRSVVCGSAKQAVSLLTAPAQATRASDGAVPLVLLLPGGGAQYVGMGRGLYETEEVFRSSIDQC AQILVQHCDIDLRSHLYGDGGLDEQRLDVVFPAVVATEYALATQLAAWGLTPNAMLGHSLGEYTAACLSG VIDIDQVLPLVSARGRLFARMGGATTSILLPTADVTPLLSGRLVVSGITDASSCTVSGPAAEIGALEQEL EIRGVQFQRVRVSMAVHSPELDPVLGEFADILAGVTLRPPRVPYLSNVTGTWIRPEEAIDPGYWIRHSRE PVQLAAGFGELAGLPDAVLLEVGPGQTLTRLAQPQGDASFAAFATMRHRDDRRSDRRALLAAVGKAWEYG VDIDWSLFSGGRRPARVELPGYPFERQRYWIAPSDGIQPIASPEATVPVWRSTTPVIPAAELPTARWLVL VGEGTEARQFAAEFAETIGTAVDLLEPGLAPASGEYEHVVFLGDAHAARIDRDRYAQLVDAVDVAGSGVS VHVCLSNAFDVTGAEELDARQWLAFGAAQWLRRSAEARTVDVVDMDRPDVRTLIAELSVPGVNRTVAYRN GRRWILDGEPVQGTAAAWSNAAADLRGESIEVGAVQGSASASNALDDLCTRHVCAHLRSAGVALTPGAEF SRAELIARLGVVPDYHKMVDAFIRILSEDGIVASENGRLRVLKEAPTAVPDLGRWCADHPELASWAQLLD QCVGGYDDVLRGRIAGNEVVTPGGDDGLYRTVTEQRIVHSDFATYRDLIGRTLAGLAVNASPARPLRVLE IGAGRGYLTWPVIHALRGLPPGAVEYHVTDIGRSFVVAAQQQAESEGLDFVRFAALDIVADPAGQSVPLD AFDVVLAFNVLHVAPDLTGAIRNTAAFTAPGGLVFILEATCEGRGDSLIDPLLTGWLDFDDDMRTDSPLV APQQWAALLDANGFAGSTIYDSGPAGDHALIIAERPEPVRTLHPDFDRAVAAIEEIAASEPSAQRMMLTG PGTESIDAAMTEAYAHGTLAVRYRAGVADWTFVDSSACGASAVTPDRLAEVLTAPAVPAIALCGPTATAA HEGQESVPMPKESASANSSFNQRPTLATEYCAPRSELEERIAAIWRRFFGYDRIGVNDRFLELGGESLLA MQIAAEQRNALGIEVSMRQLLESTTVADIAAAMTNVPTKQDASTPPTPPARRGRAARRTADGVILLEGVH E
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_2257 | - | - | 100% (1681) | polyketide synthase |
M. abscessus ATCC 19977 | MAB_2256 | - | 0.0 | 42.20% (929) | polyketide synthase |
M. abscessus ATCC 19977 | MAB_0939 | - | e-145 | 37.24% (905) | polyketide synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2960 | ppsE | 0.0 | 42.92% (897) | phenolpthiocerol synthesis type-I polyketide synthase PPSE |
M. gilvum PYR-GCK | Mflv_3390 | - | 0.0 | 43.31% (905) | beta-ketoacyl synthase |
M. tuberculosis H37Rv | Rv2935 | ppsE | 0.0 | 42.92% (897) | phenolpthiocerol synthesis type-I polyketide synthase PPSE |
M. leprae Br4923 | MLBr_02353 | - | 0.0 | 41.49% (899) | polyketide synthase |
M. marinum M | MMAR_1772 | ppsE | 0.0 | 42.42% (891) | phenolpthiocerol synthesis type-I polyketide synthase PpsE |
M. avium 104 | MAV_3108 | - | 1e-149 | 35.94% (971) | erythronolide synthase, modules 3 and 4 |
M. smegmatis MC2 155 | MSMEG_0408 | - | 1e-148 | 37.85% (901) | type I modular polyketide synthase |
M. thermoresistible (build 8) | TH_4621 | - | 1e-131 | 35.79% (908) | PUTATIVE mycocerosic acid synthase |
M. ulcerans Agy99 | MUL_2015 | ppsE | 0.0 | 42.42% (891) | phenolpthiocerol synthesis type-I polyketide synthase PpsE |
M. vanbaalenii PYR-1 | Mvan_3123 | - | 0.0 | 41.81% (928) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDR TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 WDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQH TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 RILMETAWRAVEHSGIAPTSLANSNTGVFVGLATHDYLGMASDELTYPEI TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 NECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 CGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLI TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 GSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLP TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 IEVVRETVPWQRNGKPRIAGVSSFGFAGTNAHVILEEAPAVGTPATTEPV TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 EDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAGTARA TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 HLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQ TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 GSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVA TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 GVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSV TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 AAYNGANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILD TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 DFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAK TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 SVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTADH TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 RQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNK TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 LAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAAADWILVGDDTAAVL TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 EFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDG TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 AAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDT TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 VVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRDGE TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 DQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 YLASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHDV TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 ARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWH TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 LSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRER TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 GVTAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPV TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 --------------------------------------------MPGTEQ MSMEG_0408|M.smegmatis_MC2_155 QGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAAAPATVPGKPP TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 HLDYLKRLTADLRR------------------------------------ MSMEG_0408|M.smegmatis_MC2_155 LVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSL TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK ----------------------------------------MTSGTRDSTS Mvan_3123|M.vanbaalenii_PYR-1 ----------------------------------------MTSGASNNT- MAV_3108|M.avium_104 ----------------------------------------------TRRR MSMEG_0408|M.smegmatis_MC2_155 MAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQ TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 ---------------------------------------------MTVEM MMAR_1772|M.marinum_M ---MSTIPDNAIAVVGMAGKFPGAKD-VSTFWSNLRRGKESIVTLSEEE- MUL_2015|M.ulcerans_Agy99 ---MSTIPDNAIAVVGMAGKFPGAKD-VSTFWSNLRRGKESIVTLSEEE- Mb2960|M.bovis_AF2122/97 ----MSIPENAIAVVGMAGRFPGAKD-VSAFWSNLRRGKESIVTLSEQE- Rv2935|M.tuberculosis_H37Rv ----MSIPENAIAVVGMAGRFPGAKD-VSAFWSNLRRGKESIVTLSEQE- MLBr_02353|M.leprae_Br4923 ----MITPDNAIAVVGMAGKFPGAND-VSAFWTNLRRGKESIVTLSEQE- Mflv_3390|M.gilvum_PYR-GCK DSPQDSLPDNAIAVIGMAGRFPGAQS-VSEFWRNLRGGVESIVDLSESE- Mvan_3123|M.vanbaalenii_PYR-1 ----DELPDNAIAVIGMAGRFPGAGS-VSEFWRNLRNGVESIVDLPEDE- MAV_3108|M.avium_104 VAELEGRLSEPVAVVGMACRYAGGVDSPEALWDLVIEGRDTVSDFPVDRG MSMEG_0408|M.smegmatis_MC2_155 ASTVTARTDDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDR- TH_4621|M.thermoresistible__bu VNIVGDTPVNAVAVIGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDR- MAB_2257|M.abscessus_ATCC_1997 DAPTTETGLADIAIVGMQCRFAGADD-VDKYWSLLSEKRE---------- :*::.: : .*. . . * : : MMAR_1772|M.marinum_M --LREAGVSDKTLADPSYVRRAPLVDGIDEFDADFFGFPPLAAQVLDPQH MUL_2015|M.ulcerans_Agy99 --LREAGVSDKTLADPSYVRRAPLVDGIDEFDADFFGFPPLAAQVLDPQH Mb2960|M.bovis_AF2122/97 --LRDAGVSDKTLADPAYVRRAPLLDGIDEFDAGFFGFPPLAAQVLDPQH Rv2935|M.tuberculosis_H37Rv --LRDAGVSDKTLADPAYVRRAPLLDGIDEFDAGFFGFPPLAAQVLDPQH MLBr_02353|M.leprae_Br4923 --LRDNGVSDKALADPAYVRRAPLLDGIDEFDADFFGLPPLAAQVLDPQH Mflv_3390|M.gilvum_PYR-GCK --LLAAGVTEQTLANRSYVRRAALMSGIEEFDADFFGFTPQAAKALDPQH Mvan_3123|M.vanbaalenii_PYR-1 --LLANGVTERTLSNRSYVRRAGLMPGIDEFDADFFGFTPYAARMLDPQH MAV_3108|M.avium_104 WDVEGLYDPDPDAKGKMYTRQGSFLQHAGDFDAGFFGIGPSEALAMDPQQ MSMEG_0408|M.smegmatis_MC2_155 WDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQ TH_4621|M.thermoresistible__bu WDADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQ MAB_2257|M.abscessus_ATCC_1997 ----GARSLDGLAAAPGWVRREAAIDGIELFDATFFGYPPAEAAMIDPQH : * : **. *** * ::**: MMAR_1772|M.marinum_M RLFLQCAWHALEDANCDPAKFDGSIGVYGTSSPSGYLLHNLLSHRDPNTV MUL_2015|M.ulcerans_Agy99 RLFLQCAWHALEDANCDPAKFDGSIGVYGTSSPSGYLLHNLLSHRDPNTV Mb2960|M.bovis_AF2122/97 RLFLQCAWHALEDAGADPARFDGSIGVYGTSSPSGYLLHNLLSHRDPNAV Rv2935|M.tuberculosis_H37Rv RLFLQCAWHALEDAGADPARFDGSIGVYGTSSPSGYLLHNLLSHRDPNAV MLBr_02353|M.leprae_Br4923 RLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSGYLLHNLLSHRDPHTV Mflv_3390|M.gilvum_PYR-GCK RLFLQTVFHAFEDAGYDPKGLEATVGVFGTSSTSGYLLHNLMSNYDPMMV Mvan_3123|M.vanbaalenii_PYR-1 RLFLQTVFHAMEDAGYDPKGLEATVGVFGTSSSSGYLLHNLMSNFDPMMV MAV_3108|M.avium_104 RIMLEICWEALERAGIDPSALRGTA---------TGVFAGVIHAGYG--- MSMEG_0408|M.smegmatis_MC2_155 RLMLETVWEGLERAGYAPSDLRGSR---------TGVFTGVAANEYAHLL TH_4621|M.thermoresistible__bu RLLLETSWEAMEHAGLTPADVEGSS---------TGVFVGLS-HDDYALL MAB_2257|M.abscessus_ATCC_1997 RLFLECAYHVFEQAGYDPDRYEGLVGVYAGSGQSSYLIANVLPHLGVSPS *::*: :. :* *. * . :: .: MMAR_1772|M.marinum_M LAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVH MUL_2015|M.ulcerans_Agy99 LAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVH Mb2960|M.bovis_AF2122/97 LAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVH Rv2935|M.tuberculosis_H37Rv LAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVH MLBr_02353|M.leprae_Br4923 LAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVALH Mflv_3390|M.gilvum_PYR-GCK IGQGASFDMVSLSLSNDKDHLATRVAHSYDLRGPALSVATACSSSLVAVH Mvan_3123|M.vanbaalenii_PYR-1 IGQGASFEMVNLSLQNDKDHLATRAAHQFDFRGPALSVATACSSSLVAVH MAV_3108|M.avium_104 -GEVKGELEGYGLTGSTLSVTSGRVSYVLGLEGPAVSVDTACSSSLVAMH MSMEG_0408|M.smegmatis_MC2_155 SAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVH TH_4621|M.thermoresistible__bu TSDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTACSSSLLAVH MAB_2257|M.abscessus_ATCC_1997 SADALPAG-----FANSPGSLPGRVSYHLNLTGPSIAVSTACSTSLVAVH .: . . . * :. .. **:::* ****::*:*:* MMAR_1772|M.marinum_M LACLSLLSGECDVALAGGSSLCVPHHVGYFTSPGSMVSAVGHCRPFDVRS MUL_2015|M.ulcerans_Agy99 LACLSLLSGECDVALAGGSSLCVPHHVGYFTSPGSMVSAVGHCRPFDVRS Mb2960|M.bovis_AF2122/97 LACLSLLSGECDMALAGGSSLCIPHRVGYFTSPGSMVSAVGHCRPFDVRA Rv2935|M.tuberculosis_H37Rv LACLSLLSGECDMALAGGSSLCIPHRVGYFTSPGSMVSAVGHCRPFDVRA MLBr_02353|M.leprae_Br4923 LACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDVRA Mflv_3390|M.gilvum_PYR-GCK LACQSILNGECDIALAGGSSLRIPNRVGYWYAQGSMVTPTGQCRPFDVRA Mvan_3123|M.vanbaalenii_PYR-1 LACQSLLNGECDIALAGGSSLRIPHHVGYWYEQGAMVSPTGQCRPFDVRS MAV_3108|M.avium_104 LAAQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALAPDGRCKVYAGAA MSMEG_0408|M.smegmatis_MC2_155 QACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASA TH_4621|M.thermoresistible__bu MACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTGRCHAFDVAA MAB_2257|M.abscessus_ATCC_1997 LACQELLDYRCDLALAGGVSLNPHPGKGYRHTPNGPLSPDGRCRAFDAAA *. : .*:***** : ::. *:*: : : MMAR_1772|M.marinum_M DGTVFGSGVAMVVLKPLQAAIDAGDRIHAVIRGSAINNDGSAKMGYAAPN MUL_2015|M.ulcerans_Agy99 DGTVFGSGAAMVVLKPLQAAIDAGDRIHAVIRASAINNDGSAKMGYAAPN Mb2960|M.bovis_AF2122/97 DGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGSAINNDGSAKMGYAAPN Rv2935|M.tuberculosis_H37Rv DGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGSAINNDGSAKMGYAAPN MLBr_02353|M.leprae_Br4923 DGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPN Mflv_3390|M.gilvum_PYR-GCK DGTVFGSGVGVLVLKALEDAVADGDRIHAVIRGSALNNDGATKMTYAAPN Mvan_3123|M.vanbaalenii_PYR-1 DGTIFASGVGVVVLKALADAIDDGDHIHAVIRGSALNNDGSTKMTYAAPN MAV_3108|M.avium_104 DGTSWSEGAGVLVLERLADARRLGHPVWAVLRGSAVNQDG-ASNGLTAPN MSMEG_0408|M.smegmatis_MC2_155 DGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDG-ASSGLTVPN TH_4621|M.thermoresistible__bu DGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDG-RTENISTPS MAB_2257|M.abscessus_ATCC_1997 AGMFPGDGVGVVLLKRLSDALADGDRIRAVVKGSAVNNDGRHKTGFTAPS * ..* :: *: * * .. : **: .:: *:** . :.*. MMAR_1772|M.marinum_M PAAQADVIAEAHAVSGIDASTVSYVECHGTGTPLGDPIEIQGLRTAFEAS MUL_2015|M.ulcerans_Agy99 PAAQADVIAEAHAVSGIDASTVSYVECHGTGTPLGDPIEIQGLRTAFEAS Mb2960|M.bovis_AF2122/97 PAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPLGDPIEIQGLRAAFEVS Rv2935|M.tuberculosis_H37Rv PAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPLGDPIEIQGLRAAFEVS MLBr_02353|M.leprae_Br4923 PAAQADVIAEAHAVAGIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVS Mflv_3390|M.gilvum_PYR-GCK ALGQAEVIAEAHAIAGVDASTITYVETHGTGTPLGDPIEVEGLRQAFELA Mvan_3123|M.vanbaalenii_PYR-1 ALGQAEVIAEAHAIAGVDASSITYVETHGTGTPLGDPIEIEGLRQAFELS MAV_3108|M.avium_104 GPSQQRVIRAALANAGLSAVDVDVVEGHGTGTVLGDPIEAQALLATYGQD MSMEG_0408|M.smegmatis_MC2_155 GGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQAAAAAYGAG TH_4621|M.thermoresistible__bu IQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNSLTQVYGKT MAB_2257|M.abscessus_ATCC_1997 VTAQSEVIMAAHAVAGVEASSIGMVEAHGTGTPVGDPIEVAALTKAFRES .* : : * :*:. : :* ***** :***** . .: MMAR_1772|M.marinum_M ETTRTGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNRAIPATLHYTSP MUL_2015|M.ulcerans_Agy99 ETTRTGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNRAIPATLHYTSP Mb2960|M.bovis_AF2122/97 QTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKALPATLHYTSP Rv2935|M.tuberculosis_H37Rv QTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKALPATLHYTSP MLBr_02353|M.leprae_Br4923 QIPRPGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKAIPATLHYTSP Mflv_3390|M.gilvum_PYR-GCK EDERSAPCYLGSVKSNIGHLETAAGIAGLIKAILCLEHKAIPATLHYTSP Mvan_3123|M.vanbaalenii_PYR-1 EETRSAPCYLGSVKSNIGHLETAAGIAGLIKAILCLEHKAIPATLHYTSP MAV_3108|M.avium_104 R-PADRPLWLGSIKSNIGHTSAAAGVAGVIKMVQALRHGVMPKTMHVDVP MSMEG_0408|M.smegmatis_MC2_155 R-DADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENP TH_4621|M.thermoresistible__bu G-----PCALTSVKTNFGHAESAAGALGMMKAILALQHGVVPQNLHFTRL MAB_2257|M.abscessus_ATCC_1997 T-DRTGYCMLGSAKTNIGHTDTAAGVAGLIKAVLSIEHGVIPANLHYSAE : * *:*:** . *:* *::* : .:.: .:* .:* MMAR_1772|M.marinum_M NPELRLEQSPFVVQNKYGPWE-WDG-VLRAGVSSFGVGGTNAHVVLEEAP MUL_2015|M.ulcerans_Agy99 NPELRLEQSPFVVQNKYGPWE-WDG-VLRAGVSSFGVGGTNAHVVLEEAP Mb2960|M.bovis_AF2122/97 NPELRLDQSPFVVQSKYGPWE-CDG-VRRAGVSSFGVGGTNAHVVLEEAP Rv2935|M.tuberculosis_H37Rv NPELRLDQSPFVVQSKYGPWE-CDG-VRRAGVSSFGVGGTNAHVVLEEAP MLBr_02353|M.leprae_Br4923 NRELRLDQTPFVVQSNYGPWK-WDG-VRRAGVSSFGVGGTNVHVVLEEAS Mflv_3390|M.gilvum_PYR-GCK NPELHLDRGPFRVRAQDGPWE-SDG-IRRAGVSSFGVGGTNAHIILEEAP Mvan_3123|M.vanbaalenii_PYR-1 NPELHLDRGPFRIRSSDGPWE-SDG-IRRAGVSSFGVGGTNAHIVLEEAP MAV_3108|M.avium_104 SPHVDWSAGAVSLLTDPRPWP-EHGGPRRAGVSSFGISGTNAHVIVEQAP MSMEG_0408|M.smegmatis_MC2_155 SPHIPWDALPVRVIDEPVPWQ-TNGRVRRAGVSSFGFTGTNAHVLVEEAP TH_4621|M.thermoresistible__bu PDEMAAIETNLFVPQATTLWPVREGCPRRAAVSSYGMSGTNVHAVLEQAP MAB_2257|M.abscessus_ATCC_1997 NPLLDLAGSPFRVAADTVDWPEGDG-PRRAGVSAFGIGGTNAHVVLEQAP : . : * .* **.**::*. ***.* ::*:*. MMAR_1772|M.marinum_M --------------TVPAHDEPAGPQVLLLSAQTAAALTESRTALAEVLE MUL_2015|M.ulcerans_Agy99 --------------TVPAHDEPAGPQVLLLSAQTAAALTESRTALAEVLG Mb2960|M.bovis_AF2122/97 A----------EASEVSAHAEPAGPQVILLSAQTAAALGESRTALAAALE Rv2935|M.tuberculosis_H37Rv A----------EASEVSAHAEPAGPQVILLSAQTAAALGESRTALAAALE MLBr_02353|M.leprae_Br4923 V----------EASTVAAS---TGPQVILLSAQTAAALGESREALATVLE Mflv_3390|M.gilvum_PYR-GCK -----------VAPARAQTSSPARPSVLVLSARTQEALEDSRATLARELG Mvan_3123|M.vanbaalenii_PYR-1 -----------TAPVPAPRSG---PQVLVLSARTEETLAQSRAALAAELS MAV_3108|M.avium_104 -------AAAETEAAPASSTMPDAVVPWVVSARSAEALAGQARRLLDHVT MSMEG_0408|M.smegmatis_MC2_155 PQLHTADAAPVEPAATAEAGTDDSPQVLALSARSPEALVELARRYDDWLS TH_4621|M.thermoresistible__bu EP--------VQRPEESADTDAAGPLVFALSSTSAEELRRTAGRLAEWVE MAB_2257|M.abscessus_ATCC_1997 D----------HVEAESPGTDGGLESLLVLSAATPSALDQQAKQLADYVR . :*: : * : MMAR_1772|M.marinum_M RS-DSPDLSDVAYTLSRRRKHNVTMAAVVSDREEAATALRAADND----S MUL_2015|M.ulcerans_Agy99 RS-DSPDLSDVAYTLSRRRKHNVTMAAVVSDREEAATALRAADND----S Mb2960|M.bovis_AF2122/97 TQ-DGPRLSDVAYTLARRRKHNVTMAAVVHDREHAATVLRAAEHD----N Rv2935|M.tuberculosis_H37Rv TQ-DGPRLSDVAYTLARRRKHNVTMAAVVHDREHAATVLRAAEHD----N MLBr_02353|M.leprae_Br4923 KP-GAPDLSDVAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHD----N Mflv_3390|M.gilvum_PYR-GCK EN-AEISLPDVAYTLGRRRKEPIRLAAVVRDQANAATVLSAAETDGATDN Mvan_3123|M.vanbaalenii_PYR-1 EV-DEISLPDAAYTLTHRRKDPVRLAAVVHDQENAATVLSAAETD----N MAV_3108|M.avium_104 AD-AQASPLDVGWSLVSTRAVFEHRAVVVGRERGALATGLAGLAS----- MSMEG_0408|M.smegmatis_MC2_155 AT-PGLDIADVCHTAGVGRSHFEYRAALVVDSVERAREGLAALAE----- TH_4621|M.thermoresistible__bu AHTDEVVPADLAYTLARRRAHRPVRTTVIADGVEALTAGLREVADG---- MAB_2257|M.abscessus_ATCC_1997 SN-SEVDPADVADTLQWGRRKLPYRRSVVCGSAKQAVSLLTAPAQ----- * : * :: . MMAR_1772|M.marinum_M IFVGESVAG-----VADATAAAAERVVFLFPGQGAQHVGMAKGLYETEPV MUL_2015|M.ulcerans_Agy99 IFVGESVAG-----VADATAAAAERVVFLFPGQGAQHVGMAKGLYETEPV Mb2960|M.bovis_AF2122/97 VFVGEAAHDGEHGDRADAAPT-SDRVVFLFPGQGAQHVGMAKGLYDTEPV Rv2935|M.tuberculosis_H37Rv VFVGEAAHDGEHGDRADAAPT-SDRVVFLFPGQGAQHVGMAKGLYDTEPV MLBr_02353|M.leprae_Br4923 VFVGESGADTGRSAAASITTLGSDRVVFLFPGQGAQHVGMAKGLYDTESV Mflv_3390|M.gilvum_PYR-GCK VFIGR--------GHPDWDSSATDRIAFLFPGQGAQHIGMARGLHDNEPV Mvan_3123|M.vanbaalenii_PYR-1 VFIGR--------AVPDLQDSA-ERVAFLFPGQGAQHVGMARGLYDNEPV MAV_3108|M.avium_104 --------GRPGPATVVGRARSTGKTVLVFPGQGSQTLGMGRQLYERFEV MSMEG_0408|M.smegmatis_MC2_155 --------GRTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPV TH_4621|M.thermoresistible__bu -----------DAPYQPAVGMDDKAPVWVFSGQGSQWAGMGAELLATEQV MAB_2257|M.abscessus_ATCC_1997 ---------------ATRASDGAVPLVLLLPGGGAQYVGMGRGLYETEEV . ::.* *:* **. * * MMAR_1772|M.marinum_M FAEHFDACAAGFRAEMG---VDLNAEIFNGTATDLERIDRSQPALFTVEY MUL_2015|M.ulcerans_Agy99 FAEHFDACAAGFRAEMG---VDLNAEIFNGTGTDLERIDRSQPALFTVEY Mb2960|M.bovis_AF2122/97 FAQHFDTCAAGFRDETG---IDLHAEVFDGTATDLERIDRSQPALFTVEY Rv2935|M.tuberculosis_H37Rv FAQHFDTCAAGFRDETG---IDLHAEVFDGTATDLERIDRSQPALFTVEY MLBr_02353|M.leprae_Br4923 FAEHFDTCSAGFREAMDD--LDLHSAIFNGTAIDLERIDRSQPALFTVEY Mflv_3390|M.gilvum_PYR-GCK FARYFDECATAFSDEMG---FDLRAEIFDGVGRNLEHTDRAQPALFTVEY Mvan_3123|M.vanbaalenii_PYR-1 FKRHFDECATAFSDDMG---YDLRAEIFDGVGRNLEHTDRAQPALFTVEY MAV_3108|M.avium_104 FAGALDEAVAVVDEHSRLSVREVMWGAD---PELLQSTEFAQPALFVFEV MSMEG_0408|M.smegmatis_MC2_155 FAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEM TH_4621|M.thermoresistible__bu FAAKIAEIEPLVARESG-----FSVTEAMTASETVTGIDRVQPTLFAIQV MAB_2257|M.abscessus_ATCC_1997 FRSSIDQCAQILVQHCD---IDLRSHLYGDGGLDEQRLDVVFPAVVATEY * . . . . *::.. : MMAR_1772|M.marinum_M ALAKLVDTYGVRAGAYIGYSTGEYIAATLAGVFDLETAIKTVSLRARLMH MUL_2015|M.ulcerans_Agy99 ALAKLVDTYGVRAGAYIGYSTGEYIAATLAGVFDLETAIKTVSLRARLMH Mb2960|M.bovis_AF2122/97 ALAKLVDTFGVRAGAYIGYSTGEYIAATLAGVFDLQTAIKTVSLRARLMH Rv2935|M.tuberculosis_H37Rv ALAKLVDTFGVRAGAYIGYSTGEYIAATLAGVFDLQTAIKTVSLRARLMH MLBr_02353|M.leprae_Br4923 ALAKLVESFGVGAGAYIGYSTGEYIAATLAGVFDLETAIKTVSLRARLMH Mflv_3390|M.gilvum_PYR-GCK ALARLIQSYGVEPAIMAGHSIGEYPAATLAGVFDLDTAVKVVATRAKLMH Mvan_3123|M.vanbaalenii_PYR-1 ALAKLVQSYGVEPAIMAGHSIGEYPAATIAGVFDLDTAVKVVSKRAKLMH MAV_3108|M.avium_104 ALAALWESLGVTPDVVMGHSVGEIAAACVAGVLSLRDAARLVAARGALMA MSMEG_0408|M.smegmatis_MC2_155 GLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFG TH_4621|M.thermoresistible__bu ALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRRSRLCL MAB_2257|M.abscessus_ATCC_1997 ALATQLAAWGLTPNAMLGHSLGEYTAACLSGVIDIDQVLPLVSARGRLFA .** : .: . *:* *: ** ::*.:.: :. *. : MMAR_1772|M.marinum_M ESPPG-AMVAVAVGPDEIAQYLGD----GVELSAVNDPGNCVVAGPKDEI MUL_2015|M.ulcerans_Agy99 ESPPG-AMVAVAVGPDDFAQYLGD----GVELSAVNDPGNCVVAGPKDEI Mb2960|M.bovis_AF2122/97 ESPPG-AMVAVALGPDDVTQYLPP----EVELSAVNDPGNCVVAGPKDQI Rv2935|M.tuberculosis_H37Rv ESPPG-AMVAVALGPDDVTQYLPP----EVELSAVNDPGNCVVAGPKDQI MLBr_02353|M.leprae_Br4923 ESPPG-AMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNCVVAGPKDQI Mflv_3390|M.gilvum_PYR-GCK AAPRG-VMIAVPLSPDAVAEYLTP----DVDIATINDPGSCVVAGTDEAI Mvan_3123|M.vanbaalenii_PYR-1 AAPRG-VMVAVPLSPEAVAEHLTP----DVDVATINDPGSCVVAGSEEAI MAV_3108|M.avium_104 ALPPGGVMVAVTAGESQVGPLLGGG----VSIAAVNGPDAVVLSGEQEAV MSMEG_0408|M.smegmatis_MC2_155 SLPEGGRMVAVFADAEHVEQVAGEFP--RVSVGAYNGP-NTVLSGPGEDL TH_4621|M.thermoresistible__bu RLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGGATDTV MAB_2257|M.abscessus_ATCC_1997 R--MGGATTSILLPTADVTPLLSG----RLVVSGITDASSCTVSGPAAEI . :: . : :. .. .:.* : MMAR_1772|M.marinum_M RAFSQRLNEAGIPVRRVRATHAFHSSSMEPMLGEFQEFLSRQQLRAPQTP MUL_2015|M.ulcerans_Agy99 RAFSQRLNEAGIPVRRVRATHAFHSSSMEPMLGEFQEFLSRQQLRAPQTP Mb2960|M.bovis_AF2122/97 RALRQRLTEAGIPVRRVRATHAFHTSAMDPMLGQFQEFLSRQQLRPPRTP Rv2935|M.tuberculosis_H37Rv RALRQRLTEAGIPVRRVRATHAFHTSAMDPMLGQFQEFLSRQQLRPPRTP MLBr_02353|M.leprae_Br4923 RAFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTP Mflv_3390|M.gilvum_PYR-GCK RAFQAGLAEKGVAARRVRTAHAFHSRLMDPVVAEFTAFLSGLTLREPQIP Mvan_3123|M.vanbaalenii_PYR-1 RTFQAALAEKGVAARRVRTSHAFHSRLMDPVVAEFGAFLSGVTLREPQIP MAV_3108|M.avium_104 AAVADRLAGSGARVHRLAVSHAFHSALMEPMLDGFAAAAAGIEPRPPRIP MSMEG_0408|M.smegmatis_MC2_155 EEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAYAAQFQFAAPTLP TH_4621|M.thermoresistible__bu RELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPMTPTVP MAB_2257|M.abscessus_ATCC_1997 GALEQELEIRGVQFQRVRVSMAVHSPELDPVLGEFADILAGVTLRPPRVP . * : . * *: ::*:: : : * * MMAR_1772|M.marinum_M LLSNLTGTWLSEQQVTDPATWARQISSTVRFADELDVVLSQPNRILVEIG MUL_2015|M.ulcerans_Agy99 LLSNLTGTWLSEQQVTDPATWARQISSTVRFADELDVVLSQPNRILVEIG Mb2960|M.bovis_AF2122/97 LLSNLTGSWMSDQQVVDPASWTRQISSPIRFADELDVVLAAPSRILVEVG Rv2935|M.tuberculosis_H37Rv LLSNLTGSWMSDQQVVDPASWTRQISSPIRFADELDVVLAAPSRILVEVG MLBr_02353|M.leprae_Br4923 LLSNLTGTWMSEQQVTDPENWTRQISSTIRFADELDVVLSQSGRVLVEVG Mflv_3390|M.gilvum_PYR-GCK LLSNVTGTTMSASEATNPSTWARQIRATVRFADELDALLAAPDRVLVEVG Mvan_3123|M.vanbaalenii_PYR-1 LLSNITGTTMTAAEATNPSTWARQIRATVRFADELDALLAAPDRVLVEVG MAV_3108|M.avium_104 LVSNLTG-QLAGPGYGTPQYWVDHVRRPVRFVDGVRLAESQGAGVFLEVG MSMEG_0408|M.smegmatis_MC2_155 LVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIG TH_4621|M.thermoresistible__bu YYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGFRVFGELS MAB_2257|M.abscessus_ATCC_1997 YLSNVTGTWIRPEEAIDPGYWIRHSREPVQLAAGFGELAGLPDAVLLEVG . *. . * : :::. . :: *:. MMAR_1772|M.marinum_M PGGSLTGSAIRHPKWSDGHRSVRLMRHPIQNLDDRETFLRALGELWSAGV MUL_2015|M.ulcerans_Agy99 PGGSLTGSAIRHPKWSDGHRSVRLMRHPIQNLDDRETFLRALGELWSAGV Mb2960|M.bovis_AF2122/97 PGGSLTGSAMRHPKWSTTHRTVRLMRHPLQDVDDRDTFLRALGELWSAGV Rv2935|M.tuberculosis_H37Rv PGGSLTGSAMRHPKWSTTHRTVRLMRHPLQDVDDRDTFLRALGELWSAGV MLBr_02353|M.leprae_Br4923 PGGSLTGSAMRHPRWSSGHRAVRLMRHPLQNVDDHDTFLRALGELWSAGI Mflv_3390|M.gilvum_PYR-GCK PGGTLTSSAGRHPRWSERHRAVRLMRHQAQNRSDDDTFHLALGQLWAADV Mvan_3123|M.vanbaalenii_PYR-1 PGGTLTSSAGRHPKWTERHRAVRLMRHQAQNRNDHDTFLLALGQLWAADV MAV_3108|M.avium_104 PGAALTSAVEQS--LTSDRAMS--VVTMPKGRPEVDSLLTAAARLFTAGA MSMEG_0408|M.smegmatis_MC2_155 PQPVLTGAAVQV--WPEHMAAPRAVASLRKGVADRRQIADALASAYVGGH TH_4621|M.thermoresistible__bu PHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHG--VRTMVGDLFAAGA MAB_2257|M.abscessus_ATCC_1997 PGQTLTRLAQPQ--GDASFAAFATMRHRDDRRSDRRALLAAVGKAWEYGV * ** . . . . . : . MMAR_1772|M.marinum_M DVDWTPR---RAASPRIVSLPGYPFARQRHWVEPKHMAWAQIPTASNG-- MUL_2015|M.ulcerans_Agy99 DVDWTPR---RAASPRIVSLPGYPFARQRHWVEPKHMAWAQIPTASNG-- Mb2960|M.bovis_AF2122/97 EVDWTPR---RPAVPHLVSLPGYPFARQRHWVEPNHTVWAQAPGANNG-- Rv2935|M.tuberculosis_H37Rv EVDWTPR---RPAVPHLVSLPGYPFARQRHWVEPNHTVWAQAPGANNG-- MLBr_02353|M.leprae_Br4923 EVDWAPQ---RSVMPHLVSLPGYPFARQRHWVEPRYTIWAQIPGASSG-- Mflv_3390|M.gilvum_PYR-GCK DVDWTQGDQDAADARTLVTLPGYPFARQRHWVEYN----ASSAWVANG-- Mvan_3123|M.vanbaalenii_PYR-1 EVDFNQG---AEEDRTLITLPGYPFAKQRHWVEHN----ANAAWLAGG-- MAV_3108|M.avium_104 DVRWSAAFTGLHARR--VDLPTYAFARRRFWLSGDAVGSANIASLGLA-- MSMEG_0408|M.smegmatis_MC2_155 RPDFAAVHR-QPRRP--VELPTYPFQRRRFWP------KASSIAVDGG-- TH_4621|M.thermoresistible__bu AVDFAALYP----SGRLVDAPLPTWTRRKLVLSREN--GEQQTRGGCT-- MAB_2257|M.abscessus_ATCC_1997 DIDWSLFSG--GRRPARVELPGYPFERQRYWIAPSDGIQPIASPEATVPV : : * .: ::: MMAR_1772|M.marinum_M SSVGAKLGSGADSGIRGG-AQTGESQTEDVLQRIWSQCLGVGSVDRNANF MUL_2015|M.ulcerans_Agy99 SSVGAKLGSGADSGIRGG-AQTGESQTEDVLQRIWSQCLGVGSVDRNANF Mb2960|M.bovis_AF2122/97 SPAGTADGSTA--ATVDA-ARNGESQTEVTLQRIWSQCLGVSSVDRNANF Rv2935|M.tuberculosis_H37Rv SPAGTADGSTA--ATVDA-ARNGESQTEVTLQRIWSQCLGVSSVDRNANF MLBr_02353|M.leprae_Br4923 SPVDSSVDS----ATVEG-VRGGESQTEATLQRIWSQCLGVSSVDRNANF Mflv_3390|M.gilvum_PYR-GCK SGAAGVSATGAQAGSAAG-GAGGGSSVEASLQRIWAQCLGVNEIDRHANF Mvan_3123|M.vanbaalenii_PYR-1 AGADGTAAAAGSAGVAPV-AAGGTSTVEAKLARIWSQCLGLSDIDRNANF MAV_3108|M.avium_104 EAEHPLLGAVLDRPDSGG-VVLTGRLSTAAQPWLADHAVAGTVLFPGAGF MSMEG_0408|M.smegmatis_MC2_155 TAASGILGSGKD-LASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATY TH_4621|M.thermoresistible__bu ITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAY MAB_2257|M.abscessus_ATCC_1997 WRSTTPVIPAAELPTARWLVLVGEGTEARQFAAEFAETIGTAVDLLEPGL . . : . MMAR_1772|M.marinum_M FDMGGDS--------------------------------------LMAIS MUL_2015|M.ulcerans_Agy99 FDMGGDS--------------------------------------LMAIS Mb2960|M.bovis_AF2122/97 FDLGGDS--------------------------------------LMAIS Rv2935|M.tuberculosis_H37Rv FDLGGDS--------------------------------------LMAIS MLBr_02353|M.leprae_Br4923 FDLGGDS--------------------------------------LMAIS Mflv_3390|M.gilvum_PYR-GCK FEIGGDS--------------------------------------LVAIS Mvan_3123|M.vanbaalenii_PYR-1 FEIGGDS--------------------------------------LIAIS MAV_3108|M.avium_104 VELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQLQVVVADAAGQPGSRS MSMEG_0408|M.smegmatis_MC2_155 AAMALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHPADGGS-VLS TH_4621|M.thermoresistible__bu CEMALAAAR--------EVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASA MAB_2257|M.abscessus_ATCC_1997 APASGEYEHVVFLG------------------------------DAHAAR . MMAR_1772|M.marinum_M IAMSAANEGLTITPQDLYEHPTLASLTAAIDASFASS------------- MUL_2015|M.ulcerans_Agy99 IAMSAANEGLTITPQDLYEHPTLASLTAAIDASFASS------------- Mb2960|M.bovis_AF2122/97 IAMAAANEGLTITPQDLYEYPTLASLTAAVDASFASS------------- Rv2935|M.tuberculosis_H37Rv IAMAAANEGLTITPQDLYEYPTLASLTAAVDASFASS------------- MLBr_02353|M.leprae_Br4923 ISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASS------------- Mflv_3390|M.gilvum_PYR-GCK VAMTAGHAGLDLTPQDLYENQTVASLAKVLTARYAEG------------- Mvan_3123|M.vanbaalenii_PYR-1 VAMTAGHEGLDLTPQDLYENQTVAALAKVLTARYAEG------------- MAV_3108|M.avium_104 VAVYSR---VAQSEWTLHAEGVLSEAAPAPAAELSVWPPADAEAVDVAG- MSMEG_0408|M.smegmatis_MC2_155 FQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLER TH_4621|M.thermoresistible__bu VEPGTLEFAVETAKDGEHERRATAVLGAADDTEPPQAHDIDALLAEHPTR MAB_2257|M.abscessus_ATCC_1997 IDRDRYAQLVDAVDVAGSGVSVHVCLSNAFDVTGAEELDAR--------- . . . MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 -----GYDDLAGRGYGYGPAFRG-LRAVWRRGAETFAEVELPEQAGVSTG MSMEG_0408|M.smegmatis_MC2_155 MRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLG TH_4621|M.thermoresistible__bu IEGDELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQIRSQ MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 RFGIHPVLLD-------AALHALGVADKRL-ETVLPFSWQGVSLHAAGAS MSMEG_0408|M.smegmatis_MC2_155 SEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEKMPR TH_4621|M.thermoresistible__bu QAPYGIHPALLDACFQSVAAHPDVQGAGSGLLLPLGVRRLQAFGPTRGAR MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 RVRVRLAPAG------AGAVSVELADASGVPVLSVRELVTRAVSAEQLAA MSMEG_0408|M.smegmatis_MC2_155 RFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLR TH_4621|M.thermoresistible__bu YCYARVTDADGSKAEADLDVLDEHGNVLLRVQGLLMGGAAADGDDRDRVL MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 AVAVRSGSGELLDVAWSVIEPRNSLPDNPISEGVTVWEPAAVDGAGPAAV MSMEG_0408|M.smegmatis_MC2_155 GLGG-DATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPI TH_4621|M.thermoresistible__bu GERLLTIEWQRRDLPEADSAAGKWLLVSTSATADVSATRLSDALKQAGAE MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 HAAT-----HQALGVLQSRLAGEAGGVLVVSTRG---------------- MSMEG_0408|M.smegmatis_MC2_155 DRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKESGSASAESARLEA TH_4621|M.thermoresistible__bu STSMCWPQQADHADNVDRFRAGIADGVTGVVVLTGPKNGNPDDAAARRGS MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 ---------------AVGLPG--------------EDVADLAGAAVWGLV MSMEG_0408|M.smegmatis_MC2_155 EITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFG TH_4621|M.thermoresistible__bu DYVRHLVRITRELAEIDGDAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLL MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M ----------------------------------GLAKP-PEADANPAVP MUL_2015|M.ulcerans_Agy99 ----------------------------------GLAKP-PEADANPAVP Mb2960|M.bovis_AF2122/97 ----------------------------------GLAKP-PEAQANPAVP Rv2935|M.tuberculosis_H37Rv ----------------------------------GLAKP-PEAQANPAVP MLBr_02353|M.leprae_Br4923 ----------------------------------GLAKP-PEAAAHPAVP Mflv_3390|M.gilvum_PYR-GCK ----------------------------------GLARQSVDDSTSPPVP Mvan_3123|M.vanbaalenii_PYR-1 ----------------------------------GLARQTLDDAVNPPVP MAV_3108|M.avium_104 RSAQAEHPG-RVVLVDTDGS-------LDLATVIGCGEPQLVVRDGVAYR MSMEG_0408|M.smegmatis_MC2_155 RTTINEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLA TH_4621|M.thermoresistible__bu RVIGAEHPHLRTTQIDIADDADLDR--VAVQLLGGGAEDETAWRDGQWYT MAB_2257|M.abscessus_ATCC_1997 -------------------------------QWLAFGAAQWLRRSAEART . MMAR_1772|M.marinum_M PNIAYFLDRG----LRDTGRWRVPLILRLDP----QVGPEDIRAVLSAVT MUL_2015|M.ulcerans_Agy99 PNIAYFLDRG----LRDTGRWRVPLILRLDP----QVGPEDIRAVLSAVT Mb2960|M.bovis_AF2122/97 PNVTYFLDRG----LRDTGRCRVPLILRLDP----KIGLPDIRAVLTAVV Rv2935|M.tuberculosis_H37Rv PNVTYFLDRG----LRDTGRCRVPLILRLDP----KIGLPDIRAVLTAVV MLBr_02353|M.leprae_Br4923 PNIAYFLERG----LCDTGRWRVPLILRLDP----KIGSDDIRAVLTAVV Mflv_3390|M.gilvum_PYR-GCK PNVAYFLEHG----LRDVGRWRIPVILGLRS----DVGEDDVRAVLTAVT Mvan_3123|M.vanbaalenii_PYR-1 PNVAYFLEHG----LRDIGRWRIPVILGLRS----DVGEDDVRAVLTAVT MAV_3108|M.avium_104 ARLRPAGRRA----LLELPGPPAVWRLAAGD----AGTLEDLAVQEHPAA MSMEG_0408|M.smegmatis_MC2_155 SRLLPWARSG----HLTLPRG-GDFVLAPTE----RGAIDNLRLTETDVP TH_4621|M.thermoresistible__bu ARLSLSPLRPEERKQAVVDCERDGMRLEIRT----PGDLETMELAAFDRV MAB_2257|M.abscessus_ATCC_1997 VDVVDMDRPDVRTLIAELSVPGVNRTVAYRNGRRWILDGEPVQGTAAAWS : : : MMAR_1772|M.marinum_M NHHDALRLRLVENGGVWEQHIAAPAD---FTELATRQLPGDLAAGEADEH MUL_2015|M.ulcerans_Agy99 NHHDALRLRLVENGGVWEQHIAAPAD---FTELATRQLPDDLAADEADEH Mb2960|M.bovis_AF2122/97 NHHDALRLHLVGNDGIWEQHIAAPAE---FTGLSNRSVPDGVAAGSPEER Rv2935|M.tuberculosis_H37Rv NHHDALRLHLVGNDGIWEQHIAAPAE---FTGLSNRSVPNGVAAGSPEER MLBr_02353|M.leprae_Br4923 NHHDVLRLSLVDNDGMWEQHIAATGE---FTRLLTQTLPDGVAAGSAEER Mflv_3390|M.gilvum_PYR-GCK DAHDVLRVRLVERSGIWDQIIAEPGE---FTELASRELPSGVAAGSPQER Mvan_3123|M.vanbaalenii_PYR-1 EVHDALRVHLVERAGTWDQHIAEPGE---FTELVARQLPEGLAAGSPQER MAV_3108|M.avium_104 ELAPGQVRVRVAAAGVNFRDVLVALG---MYPG-AAQLGAEGAGVVTEVG MSMEG_0408|M.smegmatis_MC2_155 EPDEGYVQVRVEAAGLNFRDVLNVLG---LYPGDPGPIGGDFAGTVTQLG TH_4621|M.thermoresistible__bu PPGPGQIEVAVTASSINFADVLIAFGRYPTFDGRRPQLGTDFAGVVTAVG MAB_2257|M.abscessus_ATCC_1997 NAAADLRGESIEVGAVQGSASASNALDDLCTRHVCAHLRSAGVALTPGAE : . : .. . MMAR_1772|M.marinum_M G------------------------------------------------- MUL_2015|M.ulcerans_Agy99 S------------------------------------------------- Mb2960|M.bovis_AF2122/97 A------------------------------------------------- Rv2935|M.tuberculosis_H37Rv A------------------------------------------------- MLBr_02353|M.leprae_Br4923 A------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK E------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 E------------------------------------------------- MAV_3108|M.avium_104 AGVTDVAVGDAVMG--IFGLVGSEAAVDRRLVTRVPPGWSMAQAAGIPVV MSMEG_0408|M.smegmatis_MC2_155 AGVSGLEIGQRVYGS-MQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAA TH_4621|M.thermoresistible__bu PDVTSHRVGDRVGGLSPNGCWSTFVTCDADLAVPLPDGLTEGQAAAVSTA MAB_2257|M.abscessus_ATCC_1997 FSR----------------------------------------------- MMAR_1772|M.marinum_M -----------AVSNIVAELIAEQGDSNAPLIAVHVTAPNGGAQYLGLAL MUL_2015|M.ulcerans_Agy99 -----------AVSNIVAELIAEQGDSNAPLIAVHVTAPNGGAQYLGLAL Mb2960|M.bovis_AF2122/97 -----------AVLGILAELLEDQTDPNAPLAAVHIAAAHGGPHYLCLAI Rv2935|M.tuberculosis_H37Rv -----------AVLGILAELLEDQTDPNAPLAAVHIAAAHGGPHYLCLAI MLBr_02353|M.leprae_Br4923 -----------VVSSILAELIASQSDLNEPLTAVQITTAHGGPHYLGLAV Mflv_3390|M.gilvum_PYR-GCK -----------AVLAFLDEQVREH-QVVVPLTATLIRSGSGGPSYLALSL Mvan_3123|M.vanbaalenii_PYR-1 -----------AVLGFLDEQVREH-QVVVPLAATFIRGVTGGPSYLALSL MAV_3108|M.avium_104 FLTAYYGLSVLAGLRAGQRVLVHAATGGVGMAAVQLARHWGAEVFATASR MSMEG_0408|M.smegmatis_MC2_155 ALTVRLAFD-WAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATAST TH_4621|M.thermoresistible__bu HATAWYGLHDLARLGAGEKVLIHSATGGVGLAAIAIARSVGAQIYATAGS MAB_2257|M.abscessus_ATCC_1997 -------AELIARLGVVPDYHKMVDAFIRILSEDGIVASENGRLRVLKEA . : : .. MMAR_1772|M.marinum_M HEMVA----------DDASRQLLGADIITAFAQRLGDQEIKLDPVTTGWR MUL_2015|M.ulcerans_Agy99 HETVA----------DDASRQLLGADIITAFAQRLDDQEIKLDPVTTGWR Mb2960|M.bovis_AF2122/97 HAMVT----------DDSSRQILATDIVTAFGQRLAGEEITLEPVSTGWR Rv2935|M.tuberculosis_H37Rv HAMVT----------DDSSRQILATDIVTAFGQRLAGEEITLEPVSTGWR MLBr_02353|M.leprae_Br4923 HQMVI----------DDASRQILGTDIITAFGQRLAGEEITLEPVTTGWR Mflv_3390|M.gilvum_PYR-GCK HGIAGD------VSGDSASRDVLLTDLFTAFNQRMAGEEIVLAPVTASWR Mvan_3123|M.vanbaalenii_PYR-1 HGIAG----------DDVSRDVLLTDVFTAFSQRMAGEEIVLAPVPASWR MAV_3108|M.avium_104 GKWDTLRAMGFDDAHIADSRTLDFEQKFGAAPG--GMDVVLNSLAG-EFN MSMEG_0408|M.smegmatis_MC2_155 FKRSTLRRLGVK--YVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFV TH_4621|M.thermoresistible__bu PARRDLLRDMG-IEHVYDSRSTAFADEIRRDTDGYGVDVVLNSLPGAAQR MAB_2257|M.abscessus_ATCC_1997 PTAVPDLGRWCADHPELASWAQLLDQCVGGYDDVLRGRIAGNEVVTPGGD * : . MMAR_1772|M.marinum_M DWSVRCAALA--THPAALDTRSYWIEQSTKAN--------LWLTDG---- MUL_2015|M.ulcerans_Agy99 DWSVRCAALA--THPAALDTRSYWIEQSTKAN--------LWLTDG---- Mb2960|M.bovis_AF2122/97 EWSLRCAALA--THPAALDTRSYWIENSTKAT--------LWLADALPNA Rv2935|M.tuberculosis_H37Rv EWSLRCAALA--THPAALDTRSYWIENSTKAT--------LWLADALPNA MLBr_02353|M.leprae_Br4923 EWSLRCAALA--THPAALDTRSFWIENANKVN--------LWLADVSLNT Mflv_3390|M.gilvum_PYR-GCK EWSQRCAGLA--GHPAVLDSRDYWLQTAHRST--------LRVAGG---- Mvan_3123|M.vanbaalenii_PYR-1 EWSQRCAGLA--SHPAVLDSRDYWLQTAGAST--------LRIAGP---- MAV_3108|M.avium_104 DASLRLLGPG--GRFIEMGKTDLRDPDVVARAHPGV---RYRAFDL---M MSMEG_0408|M.smegmatis_MC2_155 EATLKATAQG--GRFAEIAKRDIWSHEQMAEARPDI---AYEIVALDTVM TH_4621|M.thermoresistible__bu AG-LELLSFG--GRFIEIGKRDIYGDTRLGLFPFRRNL-AFHGVDLGLMA MAB_2257|M.abscessus_ATCC_1997 DGLYRTVTEQRIVHSDFATYRDLIGRTLAGLAVNASPARPLRVLEIGAGR . : . MMAR_1772|M.marinum_M DAAQPPSATDLTKLPSVLNAEQTSELDDARRRFRRSIQTILLAALGRTIA MUL_2015|M.ulcerans_Agy99 DAAQPPSATDLTKLPSVLNAEQTSELDDARRRFRRSIQTILLAALGRTIA Mb2960|M.bovis_AF2122/97 HTAHPPRADELTKLSSTLSVEQTSELDDGRRRFRRSIQTILLAALGRTIA Rv2935|M.tuberculosis_H37Rv HTAHPPRADELTKLSSTLSVEQTSELDDGRRRFRRSIQTILLAALGRTIA MLBr_02353|M.leprae_Br4923 DVIQPPGADDLIRMPCTLSVEQTSELDDARRRFRRSIQAIVLAALGRTIA Mflv_3390|M.gilvum_PYR-GCK EPADRPGAADLERLSTMLSAAETGEFDDARRRLRLSAEEILLAALGRAVA Mvan_3123|M.vanbaalenii_PYR-1 EHSERPGVDDVTRLSTALSAAETGEIDDARRRLRLPVEEILLAALGRAVA MAV_3108|M.avium_104 EAGPDRIAAMLAEVMELFAAGALTPLPVKAFDARCAADAYRFVSAARHIG MSMEG_0408|M.smegmatis_MC2_155 FTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIG TH_4621|M.thermoresistible__bu DSHPHKIRELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVG MAB_2257|M.abscessus_ATCC_1997 GYLTWPVIHALRGLPPGAVEYHVTDIGRSFVVAAQQQAESEGLDFVRFAA : : . . MMAR_1772|M.marinum_M QTVGDGVVAVELDGEGRSVLR-----PDVDVRRTVGRFTTYYPVALTCAT MUL_2015|M.ulcerans_Agy99 QTVGDGVVAVELDGEGRSVLR-----PDVDVRRTVGRFTTYYPVALTCAT Mb2960|M.bovis_AF2122/97 QTVGEGVVAVELEGEGRSVLR-----PDVDLRRTVGWFTTYYPVPLACAT Rv2935|M.tuberculosis_H37Rv QTVGEGVVAVELEGEGRSVLR-----PDVDLRRTVGWFTTYYPVPLACAT MLBr_02353|M.leprae_Br4923 QTVGDGVVAVELEGEGRSVLR-----PDVDVRRTIGWFTNYYPIPLVCVK Mflv_3390|M.gilvum_PYR-GCK VTVGEGAVAVDLGGRGRSVLK-----PDVDLARTVGSFAALHPVVLT-AS Mvan_3123|M.vanbaalenii_PYR-1 ATVGEGAVSVDLGGRGRSVLK-----PDVDLQRTVGWFTTIHPVVLT-AA MAV_3108|M.avium_104 KVVLTMPDGPAGLSGGTALITGATGMAGAALARHLVARHRVPHLMLVGRR MSMEG_0408|M.smegmatis_MC2_155 KIVLQVPKPLQPQQDRSYLITGGLGAIGLHTAAYLAQLG-AGDIVLTSRR TH_4621|M.thermoresistible__bu KLVLDVPHTGRADVVVPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAA MAB_2257|M.abscessus_ATCC_1997 LDIVADPAGQSVPLDAFDVVLAFN----VLHVAPDLTGAIRNTAAFTAPG : MMAR_1772|M.marinum_M GQGAAALKGLDAVHDTLKS-VPHYGIGYGLLRYLYAPTGRVLGAQRTPDI MUL_2015|M.ulcerans_Agy99 GQGAAALKGLDAVHDTLKS-VPHYGIGYGLLRYLYAPTGRVLGAQRTPDI Mb2960|M.bovis_AF2122/97 GLG--ALAQLDAVHNTLKS-VPHYGIGYGLLRYVYAPTGRVLGAQRTPDI Rv2935|M.tuberculosis_H37Rv GLG--ALAQLDAVHNTLKS-VPHYGIGYGLLRYVYAPTGRVLGAQRTPDI MLBr_02353|M.leprae_Br4923 GQG--ALAQLDAVHNTLKS-IPHYGIGYGLLRYMYAPTGRVFSAQRTPDI Mflv_3390|M.gilvum_PYR-GCK GQ--TASAALAEVRQTLDA-VPHYGIGYGLLRYLYAPTARLLGDGRPADI Mvan_3123|M.vanbaalenii_PYR-1 RQG-SATQALGDVRETLKA-VPHYGIGYGLLRYLYAPTARVLGASRPADI MAV_3108|M.avium_104 GEAAPGMAELAAELRGAGASVSVLSCDVGDRDAVAAMLAQVPARYP-LRS MSMEG_0408|M.smegmatis_MC2_155 DPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAG TH_4621|M.thermoresistible__bu GAGCIVLNGRSAPSGEALRTIEQLRAAGTEVIVECGXXXRGQPVEVAVPT MAB_2257|M.abscessus_ATCC_1997 GLVFILEATCEGRGDSLIDPLLTGWLDFDDDMRTDSPLVAPQQWAALLDA : MMAR_1772|M.marinum_M HFRYAGTIPELPPV---DAPVQFDSDLAMPVREPLPGLGHAVEIRAYRSG MUL_2015|M.ulcerans_Agy99 HFRYAGTIPELPPV---DAPVQFDSDLAMPVREPLPGLGHAVEIRAYRSG Mb2960|M.bovis_AF2122/97 HFRYAGVIPELPSG---DAPVQFDSDMTLPVREPIPGMGHAIELRVYRFG Rv2935|M.tuberculosis_H37Rv HFRYAGVIPELPSG---DAPVQFDSDMTLPVREPIPGMGHAIELRVYRFG MLBr_02353|M.leprae_Br4923 HFRYVGVVPEPPSV---DATVQFDSDMTIPVQEPVPGMGHAIELRTYRFG Mflv_3390|M.gilvum_PYR-GCK LFSHVGTIPDAPADQPDDAPVRFDPDTAMPIRDALPGLGHALEVRIYRTG Mvan_3123|M.vanbaalenii_PYR-1 LFSHIGTIPEVPAEQPDDAPVRFDADTAMPIRDALPGLGHAVELRVYRAA MAV_3108|M.avium_104 VFHAAGVLDDAVIASLTPARIDTVLRAKVDGAWNLHELTKDLDLSAFVVF MSMEG_0408|M.smegmatis_MC2_155 IAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDDDLDFFIVS TH_4621|M.thermoresistible__bu ELRHADEHPDRRGAQLCDEFARGEQGAQRNQHRTDAGEGQRDAHPPGAVG MAB_2257|M.abscessus_ATCC_1997 NGFAGSTIYDSGPAGDHALIIAERPEPVRTLHPDFDRAVAAIEEIAASEP . : MMAR_1772|M.marinum_M S----SLH-----------------VDWWYDTRRITAETATALARSFPTA MUL_2015|M.ulcerans_Agy99 S----SLH-----------------VDWWYDTRRITAETATALARSFPTA Mb2960|M.bovis_AF2122/97 G----SLH-----------------LDWWYDTRRIPAATAEALERTFPLA Rv2935|M.tuberculosis_H37Rv G----SLH-----------------LDWWYDTRRIPAATAEALERTFPLA MLBr_02353|M.leprae_Br4923 G----SLH-----------------LDWWYDIRRIPQVTAEALAQSFPVT Mflv_3390|M.gilvum_PYR-GCK G----ELH-----------------LDWWYDIRRLGPTDVESFSRQYSAA Mvan_3123|M.vanbaalenii_PYR-1 G----VLH-----------------LDWWYDNRRLGPTDVESFARQYSEA MAV_3108|M.avium_104 S----SMAGIVGAPGQGNYAAANSFLDALAIHRHAHGLPALSVAWGMWEE MSMEG_0408|M.smegmatis_MC2_155 S----SVSSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ TH_4621|M.thermoresistible__bu HDQPD-----------------PGALSDTGLDERGGQFPGVGVQIPVADP MAB_2257|M.abscessus_ATCC_1997 SAQRMMLTG-----------PGTESIDAAMTEAYAHGTLAVRYRAGVADW :. MMAR_1772|M.marinum_M LSELIQESIAAEQEERDEDEKVGVIEAGALVDLSSLDAG----------- MUL_2015|M.ulcerans_Agy99 LSELIQESIAAEQEERDEDEKVGVIEAGALVDLPSLDAG----------- Mb2960|M.bovis_AF2122/97 LSALIQEAIAAEHTEHDDSEIVGEPEAGALVDLSSMDAG----------- Rv2935|M.tuberculosis_H37Rv LSALIQEAIAAEHTEHDDSEIVGEPEAGALVDLSSMDAG----------- MLBr_02353|M.leprae_Br4923 LSKLIQEGIATQKDAHDESEMAGAPQAGVLVDLSTLDAG----------- Mflv_3390|M.gilvum_PYR-GCK VLDISREALAEEDTDAAGDELA-------LVDLS---------------- Mvan_3123|M.vanbaalenii_PYR-1 LLDVTRDALAEEDTDAAGDELA-------LVDLS---------------- MAV_3108|M.avium_104 PSAMTAHLEERDKARMSRAGLSALSTRQALDLLDDALLGE--QPLVVGTR MSMEG_0408|M.smegmatis_MC2_155 GGMASS---EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKAN TH_4621|M.thermoresistible__bu GVGIDHRGAVRVDSGVPAQQGVDG-EVVRHRTLSSVRSGRSSRWTAPGSR MAB_2257|M.abscessus_ATCC_1997 TFVDSSACGASAVTPDRLAEVLTAPAVPAIALCGPTATAAHEGQESVPMP MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 LDRAALAQHRAALPPLLSELAGRPARRMLEHTDMVSLTGLRARLAGMNPE MSMEG_0408|M.smegmatis_MC2_155 WQRAAKVLG-SARPPILDLVLPSAAG------EATGDSELLKQLMEIPIP TH_4621|M.thermoresistible__bu CGSGRRYGGESCRRTTG---------------PAAGAAARRGRTRRRRRP MAB_2257|M.abscessus_ATCC_1997 KESASANSSFNQRPTLATEYCAPRSELEERIAAIWRRFFGYDRIGVNDRF MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 QRQAELVELVCGNAAAVLGHSTADVDPGDAFSDLGFDSLTAVELRNRLKI MSMEG_0408|M.smegmatis_MC2_155 QRAGFVTEFLQREVQNFLRLASPPAAS-SRFLDLGTDSLMAIELRNRLHS TH_4621|M.thermoresistible__bu RRPPPPPDRVRHRAGPAHGPVRR--------------------------- MAB_2257|M.abscessus_ATCC_1997 LELGGESLLAMQIAAEQRNALGIEVSMRQLLESTTVADIAAAMTNVPTKQ MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 ATG--LTLSPTVIFDHPTPAALAEHLGGQLTSAGPTPAAPAETAAPPDRS MSMEG_0408|M.smegmatis_MC2_155 QFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA----------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 DASTPPTPPARRGRAARRTADGVILLEGVHE------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3108|M.avium_104 SRIDEVVSELQTLLTQPGLSPGDRAQLVTRLQSLLSTPPQPSGHPEFPED MSMEG_0408|M.smegmatis_MC2_155 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_2257|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_1772|M.marinum_M ------------------------ MUL_2015|M.ulcerans_Agy99 ------------------------ Mb2960|M.bovis_AF2122/97 ------------------------ Rv2935|M.tuberculosis_H37Rv ------------------------ MLBr_02353|M.leprae_Br4923 ------------------------ Mflv_3390|M.gilvum_PYR-GCK ------------------------ Mvan_3123|M.vanbaalenii_PYR-1 ------------------------ MAV_3108|M.avium_104 AFDDDIATATDSQLFAILDDEAGP MSMEG_0408|M.smegmatis_MC2_155 ------------------------ TH_4621|M.thermoresistible__bu ------------------------ MAB_2257|M.abscessus_ATCC_1997 ------------------------