For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VHLQASQGNDAPVREETAVTTAKHRSVRDALPALDTALTGVDLAEQWTATADGPGRYPRVSFTPNVSIAL SDGTVLKAQVFRPADADGTPVAERLPVLLNLTPYNKSVTHLAAWLLRGLRRLGVTVPDAPPKNPRLFELS ELARALPGGGLATFGVDDALIRSGYVQAVIDVRGTGASSGDWGMFDDVEQRDTAEVVAWAQAQPWCDGSV GMYGISYCSINSLQAAGNRVPGLGAVFAVEPVSDISRDLMKTGGAQTFFMPLWMLAVALGKWLPSPSDVV RGGIAPGWLAGRLRAPLNRVIRYIFEGLRGRGTLIDNDEYFRQISPRFEDIEIPTFVYGAWDDIFGPAAL RIHRRISMPDGMFQVIINEGYHGSPGSQLGRPDGPPRLDVLQRAWFDKWLKGIDNGIDRYGPVTLQQQNG GWHTLETYPRPEAVPQRFYLDAEPSGFAAHTSLDGSLGAAAPRGRTEHRLRRRPGLLKSPTTSRLMSGMT AVLGTSGLKDSRYFERGALTFTSAAATAPWVVSGPLNLHLRTRANGAEAFWVVSVTDVAPDGFSRMLAEG ALLTSRRAVDEAKSVRGVDGDYLSPWHPTGKGQKMPVEPGVSTTLDIDLTEVDAMIKTGHRLRVVISAAS LPRYIPSIPELWASRHGQSVVLDPDQPSYLVAPVVIGARAGAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2156 | - | - | 100% (673) | peptidase |
| M. abscessus ATCC 19977 | MAB_2222c | - | 4e-20 | 22.70% (652) | peptidase |
| M. abscessus ATCC 19977 | MAB_0501c | - | 5e-11 | 21.94% (629) | peptidase S15 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1866c | - | 8e-26 | 24.56% (680) | hypothetical protein Mb1866c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1835c | - | 8e-26 | 24.56% (680) | hypothetical protein Rv1835c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_5521 | - | 5e-41 | 27.69% (614) | peptidase S15 |
| M. avium 104 | MAV_1359 | - | 4e-17 | 26.74% (288) | hydrolase CocE/NonD family protein |
| M. smegmatis MC2 155 | MSMEG_1308 | - | 4e-26 | 25.24% (618) | peptidase S15 |
| M. thermoresistible (build 8) | TH_2570 | - | 5e-06 | 28.68% (136) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_3980 | - | 1e-40 | 27.69% (614) | peptidase S15 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5521|M.marinum_M ---------------MAVQSSARRLEKASGLGKGERQLNGPQTTGREYAN
MUL_3980|M.ulcerans_Agy99 ---------------MAVQSSARRLEKTSGLGKGERQLNGPQTTGREYAN
MAV_1359|M.avium_104 ---------------MPPTRMTALDRPWRRPGALRYALNRIRGVAKPPVT
MSMEG_1308|M.smegmatis_MC2_155 --------------------------------------------------
Mb1866c|M.bovis_AF2122/97 --------------------------------MTRRGGSDAAWYSAPDQR
Rv1835c|M.tuberculosis_H37Rv --------------------------------MTRRGGSDAAWYSAPDQR
MAB_2156|M.abscessus_ATCC_1997 MHLQASQGNDAPVREETAVTTAKHRSVRDALPALDTALTGVDLAEQWTAT
TH_2570|M.thermoresistible__bu --------------------------------------------------
MMAR_5521|M.marinum_M LSEPQ--YNTMRENNVAIPVRDGTVLLADVHRPD------AQGRFPALIA
MUL_3980|M.ulcerans_Agy99 LSEPQ--YNTMRENNAAIPVRDGTVLLADVHRPD------AQGRFPALIA
MAV_1359|M.avium_104 VTDPP--ADLHVERDVAVPTRDATVLRINVFRKA------DAEPRPVILS
MSMEG_1308|M.smegmatis_MC2_155 ---------MIIERDVAVPCDDGLILRADVFRPD------DGEPAPVIMT
Mb1866c|M.bovis_AF2122/97 SAYPR--YRGMRYSSCYVTMRDGVRIAIDLYLPAGLT---SAARLPAILH
Rv1835c|M.tuberculosis_H37Rv SAYPR--YRGMRYSSCYVTMRDGVRIAIDLYLPAGLT---SAARLPAILH
MAB_2156|M.abscessus_ATCC_1997 ADGPGRYPRVSFTPNVSIALSDGTVLKAQVFRPADADGTPVAERLPVLLN
TH_2570|M.thermoresistible__bu -------MATTDRRDLRIPAHG-EQLAAYFYPPAG-----AGPTTPCIVM
. :. . : .. * ::
MMAR_5521|M.marinum_M ASPYPRQIQDLG----------------------APMGFIEAG-------
MUL_3980|M.ulcerans_Agy99 ASPYPRQIQDLG----------------------APMGFIEAG-------
MAV_1359|M.avium_104 IHPYGKDSLPKRRGNRWTFSAQYRILRQPRPVTFSALTGWEAP-------
MSMEG_1308|M.smegmatis_MC2_155 LGPYGKG-VEYSDGYAPQWNWLITTYPEVLPGSSRSYMAWETV-------
Mb1866c|M.bovis_AF2122/97 QTRYYRSLQLRWP------------LRMLLGGKPLQHIAADKR-------
Rv1835c|M.tuberculosis_H37Rv QTRYYRSLQLRWP------------LRMLLGGKPLQHIAADKR-------
MAB_2156|M.abscessus_ATCC_1997 LTPYNKSVTHLAAWLLRGLRRLGVTVPDAPPKNPRLFELSELARALPGGG
TH_2570|M.thermoresistible__bu AHGFTATRDDGLP-------------------------------------
:
MMAR_5521|M.marinum_M -----VTDFWVPRGYVHVIANVRGTGGSGGT-FGFFDAT-ERRDMHDLVE
MUL_3980|M.ulcerans_Agy99 -----VTDFWVPRGYVHVIANVRGTGGSGGT-FGFFDAT-ERRDMHDLVE
MAV_1359|M.avium_104 -----DPAWWTAQGFVVVNADSRGCGRSEGT-GNLLSHR-EAEDTYDLVQ
MSMEG_1308|M.smegmatis_MC2_155 -----DPEIWVPWGYAVVRVDSRGAGRSPGV-LDMLSPR-EVRDYHDAIE
Mb1866c|M.bovis_AF2122/97 -----RRRRFVASGYAWVDVDVRGSGASFGARVCEWSSD-EIRDGAEIVD
Rv1835c|M.tuberculosis_H37Rv -----RRRRFVASGYAWVDVDVRGSGASFGARVCEWSSD-EIRDGAEIVD
MAB_2156|M.abscessus_ATCC_1997 LATFGVDDALIRSGYVQAVIDVRGTGASSGD-WGMFDDV-EQRDTAEVVA
TH_2570|M.thermoresistible__bu ----AYAEAFHAAGYAVVLFDYRHFGASTGEPRQLLDITRQHDDYRAVVA
*:. . : * * * * . : * :
MMAR_5521|M.marinum_M WAAAQPWCDGNVGMIGISYFAMTQLEAAVERPPHLKAIFPVAATTDLYEA
MUL_3980|M.ulcerans_Agy99 WAAAQPWCDGNVGMIGISYFAMTQLEAAVERPPHLKAIFPVAATTDLYEA
MAV_1359|M.avium_104 WVAGQPWSDGNVVMLGVSYLAISQYAVAALQPPALRAICPWEGFTDAYRD
MSMEG_1308|M.smegmatis_MC2_155 WAARQPWSTGKVGLNGISYYAINQWLLAAQQPPSLAAMIPWEGAGDFYRD
Mb1866c|M.bovis_AF2122/97 WIVRQPWCNGTVAALGNSYDGTSAELLLVNQHPAVRVIAPCFSLFDVYTD
Rv1835c|M.tuberculosis_H37Rv WIVRQPWCNGTVAALGNSYDGTSAELLLVNQHPAVRVIAPCFSLFDVYTD
MAB_2156|M.abscessus_ATCC_1997 WAQAQPWCDGSVGMYGISYCSINSLQAAGNRVPGLGAVFAVEPVSDISRD
TH_2570|M.thermoresistible__bu WARTQPGVDPDRIVLWGSSFSGGHVLVVAADDPRIAAVISQAPFTDAVPT
* ** * . * : .: . *
MMAR_5521|M.marinum_M AVHHGLFSSSFVSPFLTMVGITSER-----SDALWRGKLVGLVRRVLNTP
MUL_3980|M.ulcerans_Agy99 AVHHGLFSSSFVSPFLTMVGITSER-----SDALWRGKLVGLVRRVLNTP
MAV_1359|M.avium_104 LMFPG--------------GVRELG-----FIRMWS--------------
MSMEG_1308|M.smegmatis_MC2_155 WARHG--------------GIVSNG-----FLEAWYPRQVVSVQHGNPDG
Mb1866c|M.bovis_AF2122/97 IAFPGGIHAAWFTDTWGRYNEALDRNALHEVVGWWAKLPVTGMQPVQEDR
Rv1835c|M.tuberculosis_H37Rv IAFPGGIHAAWFTDTWGRYNEALDRNALHEVVGWWAKLPVTGMQPVQEDR
MAB_2156|M.abscessus_ATCC_1997 LMKTG-----------GAQTFFMPLWMLAVALGKWLPSPSDVVRGGIAPG
TH_2570|M.thermoresistible__bu LRKVP---------------------------------------------
MMAR_5521|M.marinum_M RLHQKFATMNGEAALTMLRQLT--------KIHHNPRPWDQLWLSAAVEH
MUL_3980|M.ulcerans_Agy99 RLHQKFATMNGEAALTMLRQLT--------KIHHNPRPWDQLWLSAAVEH
MAV_1359|M.avium_104 RNVRRDTRQAYDLQDMQD------------------------------RH
MSMEG_1308|M.smegmatis_MC2_155 RMDRWQGERATGPEDLSADELA--------LNRNDP-------LPEILKR
Mb1866c|M.bovis_AF2122/97 DRSLRDGAIAAHRGNYDVHQIAGSLTFRDDVSASDPYRGQPDARLEPIGT
Rv1835c|M.tuberculosis_H37Rv DRSLRDGAIAAHRGNYDVHQIAGSLTFRDDVSASDPYRGQPDARLEPIGT
MAB_2156|M.abscessus_ATCC_1997 WLAGRLRAPLNRVIRYIFEGLRG-------------------------RG
TH_2570|M.thermoresistible__bu --------------------------------------------------
MMAR_5521|M.marinum_M PTRD---EWWDERDLNPLLDRIDVPVYLGCDWQNVPLHLPSTFAAWKALA
MUL_3980|M.ulcerans_Agy99 PTRD---EWWDERDINPLLDRIDVPVYLGCDWQNVPLNLPSTFAAWKALA
MAV_1359|M.avium_104 PLRD---EFW--RSLVPDLSAIAVPMLVCGSFSDNNLHSRGSLRAFTHSS
MSMEG_1308|M.smegmatis_MC2_155 PLDD---EFY--RDRSPDWSKVTVPFLSAANWAGFGLHPRGNFEAFTQAA
Mb1866c|M.bovis_AF2122/97 PIESGSINLISPHNYWRDVQASGAAIYSYSGWFDGGYAHAAIKRFLTVST
Rv1835c|M.tuberculosis_H37Rv PIESGSINLISPHNYWRDVQASGAAIYSYSGWFDGGYAHAAIKRFLTVST
MAB_2156|M.abscessus_ATCC_1997 TLID---NDEYFRQISPRFEDIEIPTFVYGAWDDIFGPAALRIHRRISMP
TH_2570|M.thermoresistible__bu --------------------PATIARLAVAGLRDQIGSWRGRPPRTASAV
. .
MMAR_5521|M.marinum_M DGPSTRMG---MLGEF------GLTWPWESLHLEALAWFDHWLKSRDTGI
MUL_3980|M.ulcerans_Agy99 DGPSTRMG---MLGEF------GLTWPWESLHLEALAWFDHWLKSRDTGI
MAV_1359|M.avium_104 STHARLYT---HRGGK------WATFYAEEALAEQLSFFRGVLDGAPAAR
MSMEG_1308|M.smegmatis_MC2_155 SAQKWLEA---HPGRH------EEWFYLTQGMALQKEFLDHFLKGEDNGW
Mb1866c|M.bovis_AF2122/97 PGSHLILGPWNHTGGWRVDPLRGLSRPDFDHDGELLRFIDHHVKGADTGI
Rv1835c|M.tuberculosis_H37Rv PGSHLILGPWNHTGGWRVDPLRGLSRPDFDHDGELLRFIDHHVKGADTGI
MAB_2156|M.abscessus_ATCC_1997 DGMFQVIINEGYHGSP--GSQLGRPDGPPRLDVLQRAWFDKWLKGIDNGI
TH_2570|M.thermoresistible__bu GAP-------------------------------------GAVAAMTTPD
: .
MMAR_5521|M.marinum_M LAGP----AIRYVLPGAEGWRTTETWPPPGVVYREFALRADG--------
MUL_3980|M.ulcerans_Agy99 LAGP----AIRYVLPGAEGWRTTETWPPPGVVYRKFALRADG--------
MAV_1359|M.avium_104 SVR----LEVREDRDTVTAVREESEWPLARTRWRALHLGDAG--------
MSMEG_1308|M.smegmatis_MC2_155 DTRPPVLLHIRRPFTDEVEVRTHSAWPLENTQWTEVHLDAAD--------
Mb1866c|M.bovis_AF2122/97 GSEP----PVHYFTMVENRWKSADTWPPP-ATTQSYYLSADR--------
Rv1835c|M.tuberculosis_H37Rv GSEP----PVHYFTMVENRWKSADTWPPP-ATTQSYYLSADR--------
MAB_2156|M.abscessus_ATCC_1997 DRYG-----PVTLQQQNGGWHTLETYPRPEAVPQRFYLDAEPSGFAAHTS
TH_2570|M.thermoresistible__bu AEPG-----FRAIVEPDSLWRN----------------------------
:
MMAR_5521|M.marinum_M QLG--DDEGEPGAREYLVLG----------------GGLNRAAASAID--
MUL_3980|M.ulcerans_Agy99 QLG--DDEGEPGAREYLVLG----------------GGLNRAAASAID--
MAV_1359|M.avium_104 VLR-TDPAAQPGRVAFGTR-----------------SRAACFTWTVPD--
MSMEG_1308|M.smegmatis_MC2_155 MALNFAPVDTEHSVTFDAAG----------------EPLTFLTGPLTA--
Mb1866c|M.bovis_AF2122/97 QLRPDAPDCDSGADEYVVDQTAGTGERSRWRSQVGIGGHVCYPDRKAQ--
Rv1835c|M.tuberculosis_H37Rv QLRPDAPDCDSGADEYVVDQTAGTGERSRWRSQVGIGGHVCYPDRKAQ--
MAB_2156|M.abscessus_ATCC_1997 LDGSLGAAAPRGRTEHRLRRRPGLLKSPTTSRLMSGMTAVLGTSGLKDSR
TH_2570|M.thermoresistible__bu --------------------------------------------------
MMAR_5521|M.marinum_M --PPSMLTWTSAPLTRDLDVVGDIELRLVAAATAMDT-AWIATLHEVARD
MUL_3980|M.ulcerans_Agy99 --PPSMLTWTSAPLTRDLDVVGDIELRLVAAATAMDT-AWIATLHEVARD
MAV_1359|M.avium_104 --DVELTGPMAARLWVELHGCDDANLFVGVEKWRPGRFRDRFVAFEGSYG
MSMEG_1308|M.smegmatis_MC2_155 --ETELTGPLSARLFVSSS-TVDADLFVTVQAFAPD---GREVEFQGTID
Mb1866c|M.bovis_AF2122/97 --DAKLLTYTSAPLDHPLEVTGHVVVTLFITSTSSDG-TFFVYLEDVDPR
Rv1835c|M.tuberculosis_H37Rv --DAKLLTYTSAPLDHPLEVTGHVVVTLFITSTSSDG-TFFVYLEDVDPR
MAB_2156|M.abscessus_ATCC_1997 YFERGALTFTSAAATAPWVVSGPLNLHLRTRANGAEA-FWVVSVTDVAPD
TH_2570|M.thermoresistible__bu --EFAARLMLRFPFYRPVRVAGRINAPLLVCVCDDDA-------------
:
MMAR_5521|M.marinum_M GTVSDVTAGWLRASMRRVDEKASRRGAP---ILPCREME-----AVPIGE
MUL_3980|M.ulcerans_Agy99 GTVSDVTAGWLRASMRRVDEKASRRGAP---ILPCRGME-----AVPIGE
MAV_1359|M.avium_104 YGRDRVSTGWQRVSLRALDSRLSRPGQP---VAACTDPQ-----PVAAGE
MSMEG_1308|M.smegmatis_MC2_155 P-HTPLAQGWLRASHRKLDVARSLPYRP---YHSHDELQ-----PLDPGT
Mb1866c|M.bovis_AF2122/97 GRVAYITEGQLRAIHRRLSDGPP-PYRQ---VVPYRTFASGDAWPLVPGE
Rv1835c|M.tuberculosis_H37Rv GRVAYITEGQLRAIHRRLSDGPP-PYRQ---VVPYRTFASGDAWPLVPGE
MAB_2156|M.abscessus_ATCC_1997 GFSRMLAEGALLTSRRAVDEAKSVRGVDGDYLSPWHPTGKGQKMPVEPGV
TH_2570|M.thermoresistible__bu ----------VTPPEPAIEAARRAPRGQ-----------------LRRYP
:. :
MMAR_5521|M.marinum_M DVVYRIPLVANARRFKAGCRIRLILTSDDQDPATPAIMSFRHASVGTS--
MUL_3980|M.ulcerans_Agy99 DVVYRIPLVANARRFKAGCRIRLIFTSDDQDPATPAIMSFRHASVGTS--
MAV_1359|M.avium_104 VVAVDVALGPSATLFRAGEHLRLVVAGRWLCPTNPLTGQIPAAYQNSP--
MSMEG_1308|M.smegmatis_MC2_155 IYQLDIEIWPTCIVLPAEYRIALQISGHDFEREEPKDGNEAWVSRGSGPW
Mb1866c|M.bovis_AF2122/97 IARLTFDLLPTSYLFQPGHRIRIAIAGADASHFAILPGCAPTVRVYRS--
Rv1835c|M.tuberculosis_H37Rv IARLTFDLLPTSYLFQPGHRIRIAIAGADASHFAILPGCAPTVRVYRS--
MAB_2156|M.abscessus_ATCC_1997 STTLDIDLTEVDAMIKTGHRLRVVISAASLPRYIPSIPELWASRHGQS--
TH_2570|M.thermoresistible__bu YGHFDIYHDPQVKSDQLDFLRQVLGTG-----------------------
. : :.
MMAR_5521|M.marinum_M --------------SRNTIRSSSRLHLPVLPAQSSELQS---
MUL_3980|M.ulcerans_Agy99 --------------SRNTIRSSSRLHLRVLPAQSSELQS---
MAV_1359|M.avium_104 -------------RGRVSLHWGPRRDAHLLIPEIP-------
MSMEG_1308|M.smegmatis_MC2_155 LHTHPEDRPASIYTGRTTIHTGGSTPSTLLLPVIPS------
Mb1866c|M.bovis_AF2122/97 ------------------RMHASRIDLPVIQP----------
Rv1835c|M.tuberculosis_H37Rv ------------------RMHASRIDLPVIQP----------
MAB_2156|M.abscessus_ATCC_1997 ------------------VVLDPDQPSYLVAPVVIGARAGAA
TH_2570|M.thermoresistible__bu ------------------------------------------