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PATMRDGTILRADIYRPKLKDPVPVILMRTQYGKDTAQIQPSRFRTPDWFASHCYLVVVQDVRGQGTSDG IFTEFGNDGDDGYDTVEWAAGLPGATGKVGMYGSSYVGATQWLAATTTPPHLTTIVPSNTASDYYDGWTY EGGAFRLGFVQPWAMGTIATTAAKNRADLAALEQLRAAAAERGRWLNHLPYQDLPPMQPGDPRVAPWYFD WIRHSTRDDYWKRWSIRDRYQNVTVPVLHFEGWYDAFLRGGLENFAGMTARGGSPGARRYQRMVIGPWDH LAWGRESSSPSPLLKGLGPGANSPVNEMQLAWFDHFLKGSDNGVATESPRLDYYLMGANRWKHASAWPLP QTNWTVYHLGGRGTQHNGTLRDSAAAHDAPDVYLYDPANPVPSAGGHSCCAAESAPQGRYDQRAVEQRPD VLTYTTEPLSTNTEITGPISVDLWASSSAPDTDFTAKLVAVQADGTAANLNNGIVRTSLAQSLSERRLMP IGQPHKYHIDIWPVSYQFRTGERIRLEISSSDFPQYAPNPNTAAPFGRNAELRTATQIILHDAAHPSTLT LPVIPAGDPGTETFPMPRRPDDPPGN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2222c | - | - | 100% (587) | peptidase |
| M. abscessus ATCC 19977 | MAB_0501c | - | 2e-57 | 28.45% (566) | peptidase S15 |
| M. abscessus ATCC 19977 | MAB_2156 | - | 4e-20 | 22.70% (652) | peptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2823 | - | 4e-50 | 29.98% (567) | hydrolase |
| M. gilvum PYR-GCK | Mflv_4032 | - | 4e-44 | 27.64% (568) | peptidase S15 |
| M. tuberculosis H37Rv | Rv2800 | - | 4e-50 | 29.98% (567) | hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1910 | - | 4e-48 | 29.39% (558) | hydrolase |
| M. avium 104 | MAV_3687 | - | 2e-47 | 29.07% (578) | hydrolase CocE/NonD family protein |
| M. smegmatis MC2 155 | MSMEG_2644 | - | 7e-51 | 28.69% (582) | putative hydrolase |
| M. thermoresistible (build 8) | TH_1432 | - | 2e-15 | 28.30% (311) | POSSIBLE HYDROLASE |
| M. ulcerans Agy99 | MUL_2134 | - | 4e-48 | 29.21% (558) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_2322 | - | 3e-48 | 29.26% (581) | peptidase S15 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2823|M.bovis_AF2122/97 MSTTSARPERPKLRALTGRVG----GQALGGLLGLPRATTRYTVGH-VRV
Rv2800|M.tuberculosis_H37Rv MSTTSARPERPKLRALTGRVG----GQALGGLLGLPRATTRYTVGH-VRV
MMAR_1910|M.marinum_M MSITSTDVGQPTLRALTKRVGGSAAGGALGGLLGLPRATTRYTVSR-VGV
MUL_2134|M.ulcerans_Agy99 MSITSTHVGQPTLRALTKRVGGSAAGDALGGLLGLPRATTRYTVSR-VGV
MAV_3687|M.avium_104 MSLTSLRPAQPALHTLR-HLG----GRAAGRLLGLPPATTDYTVRR-VAV
MSMEG_2644|M.smegmatis_MC2_155 ---------MPGIRRYT--------GKFAAKLLGLPPHSTDFTVHHGLRV
Mflv_4032|M.gilvum_PYR-GCK MSSELARRAR----------------RALSRVFDLPPPVCDFVVHRELRV
Mvan_2322|M.vanbaalenii_PYR-1 MSSELSRLAR----------------HALSRALHLPPPVCDYAVNRHVRV
TH_1432|M.thermoresistible__bu --------------------------------------------------
MAB_2222c|M.abscessus_ATCC_199 -----------------------------------------------MPA
Mb2823|M.bovis_AF2122/97 PMRDGVQLVADHYAPATSQPVGTLLVRGPYGRR----FPFSLVFARIYAA
Rv2800|M.tuberculosis_H37Rv PMRDGVQLVADHYAPATSQPVGTLLVRGPYGRR----FPFSLVFARIYAA
MMAR_1910|M.marinum_M PMRDGVHLVADHYCPTTSRPAGTVLVRGPYGRG----FPFSLVFARLYAA
MUL_2134|M.ulcerans_Agy99 PMRDGVHLVADHYCPTTSRPAGTVLVRGPYGRG----FPFSLVFARLYAA
MAV_3687|M.avium_104 PMRDGVELVADHYAPATSAPAGTLLVRAPYGRG----FPFALVFGGLYAA
MSMEG_2644|M.smegmatis_MC2_155 PMRDGVELVADHYEPLTTRPAGTLLVRGPYGRR----FPFSAIFAEVYAA
Mflv_4032|M.gilvum_PYR-GCK PMRDRVELVADHYAPHTASPAGTLLVRGPYGRG----LPFATMFASFYAA
Mvan_2322|M.vanbaalenii_PYR-1 PMRDGVELVADHYTPRTADPAGTLLVRGPYGRG----FPISVLFGSIYAA
TH_1432|M.thermoresistible__bu --------------------------------------------------
MAB_2222c|M.abscessus_ATCC_199 TMRDGTILRADIYRPKLKDPVPVILMRTQYGKDTAQIQPSRFRTPDWFAS
Mb2823|M.bovis_AF2122/97 RGYHVVLQSVRGTFGSGGVFEPMVNEAADGADTVAWLREQPWFTGRFGTI
Rv2800|M.tuberculosis_H37Rv RGYHVVLQSVRGTFGSGGVFEPMVNEAADGADTVAWLREQPWFTGRFGTI
MMAR_1910|M.marinum_M RGYHVVLQSVRGTFGSAGQFEPMVNEAADGADTVEWLRRQPWFTGRFATI
MUL_2134|M.ulcerans_Agy99 RGYHVVLQSVRGTFGSAGQFEPMVNEAADGADTVEWLRRQPWFTGRFATI
MAV_3687|M.avium_104 RGYHVVLQSVRGTFGSGGVFEPMAHEVADGADTVAWLREQPWFTGRFATI
MSMEG_2644|M.smegmatis_MC2_155 RGYHVVLQSVRGTFGSGGEFTPMVHEMDDGADTVAWLRTQPWFTGSFATV
Mflv_4032|M.gilvum_PYR-GCK RGYHVVFQSVRGTFGSGGEFDPFVNEVDDGADTAAWLRDQPWFTGTFATI
Mvan_2322|M.vanbaalenii_PYR-1 RGYHVVLQSVRGTFGSGGEFDPFVNEVADGADTAAWLRDQPWFTGTFATM
TH_1432|M.thermoresistible__bu --------------------------------------------------
MAB_2222c|M.abscessus_ATCC_199 HCYLVVVQDVRGQGTSDGIFTEFGNDGDDGYDTVEWAAGLPGATGKVGMY
Mb2823|M.bovis_AF2122/97 GLPYLGFTQWALLHDPPPELAAAVITVGPHDFRA-SVWGTGSFTVNDFLG
Rv2800|M.tuberculosis_H37Rv GLPYLGFTQWALLHDPPPELAAAVITVGPHDFRA-SVWGTGSFTVNDFLG
MMAR_1910|M.marinum_M GVSYLGFTQWALLQDPPPELAAAVITAGPHDLRS-SVWGTGSFAINDFLG
MUL_2134|M.ulcerans_Agy99 GVSYLGFTQWALLQDPPPELAAAVITAGPHDLRS-SVWGTGSFAINDFLG
MAV_3687|M.avium_104 GMSYLGFTQWALLQDPPPDMATAVIMVGPHDFNE-STWGTGSFAVNDFLG
MSMEG_2644|M.smegmatis_MC2_155 GLSYLGFTQWALLADPPPEMKAAVITVGPHDFSQ-SAWGTGSFTLNDFLG
Mflv_4032|M.gilvum_PYR-GCK GLSYLGFTQWALLTDPPPELAAAVITVGPDDVSG-PRWGAGSFGLNDFLG
Mvan_2322|M.vanbaalenii_PYR-1 GLSYLGFTQWALLTDPPPELKAAVITVGPDDVSG-PRWGRGSFGLNDFLG
TH_1432|M.thermoresistible__bu --------------------------------------------------
MAB_2222c|M.abscessus_ATCC_199 GSSYVGATQWLAATTTPPHLTTIVPSNTASDYYDGWTYEGGAFRLGFVQP
Mb2823|M.bovis_AF2122/97 WSD---LVSHQEDPGRIRAGIRQLTAPRRVARTAATLPLGESARTLLGTG
Rv2800|M.tuberculosis_H37Rv WSD---LVSHQEDPGRIRAGIRQLTAPRRVARTAATLPLGESARTLLGTG
MMAR_1910|M.marinum_M WSE---LVARQEDPVRIRTGIRQLTAPRRVARAAAELPMGESARTLLGTG
MUL_2134|M.ulcerans_Agy99 WSE---LVARQEDPVRIRTGIRQLTAPRRVARAAAELPMGESARTLLGTG
MAV_3687|M.avium_104 WSD---MVSHQEDPVRARAALHQLRARRKVAEAAAGVPLGEAARALLGTG
MSMEG_2644|M.smegmatis_MC2_155 WSA---MVARQEEPGVVRALVRQLRSPAEVAKAAAGVPVGPSGRRLLGAG
Mflv_4032|M.gilvum_PYR-GCK WSD---LVGRQEDPNRVRTLLRQARAQRRVTSASLRLPLAAASRELLGDG
Mvan_2322|M.vanbaalenii_PYR-1 WSH---LVGGQEDPNRLRSLLRQAGAQRRVTEASLGLPLGPASRTLLGDG
TH_1432|M.thermoresistible__bu --------------------------------------------------
MAB_2222c|M.abscessus_ATCC_199 WAMGTIATTAAKNRADLAALEQLRAAAAERGRWLNHLPYQDLPPMQPGDP
Mb2823|M.bovis_AF2122/97 --APWFESWVEHTDRDDPFWDRLRFPAALDRVQVPVLLVGGWQDIFLRQT
Rv2800|M.tuberculosis_H37Rv --APWFESWVEHTDRDDPFWDRLRFPAALDRVQVPVLLVGGWQDIFLRQT
MMAR_1910|M.marinum_M --APWFESWLEHTDHSDPFWDRMRSPDALDRVQVPVLLVGGWQDVFVQQT
MUL_2134|M.ulcerans_Agy99 --APWFESWLEHTDHSDPFWDRMRSPDALDRVQVPVLLVGGWQDVFVQQT
MAV_3687|M.avium_104 --APWFESWIEHADPSDPFWNSLRCNEALDRVRVPVLLVGGWQDLFIRQT
MSMEG_2644|M.smegmatis_MC2_155 --APWFESWLEHPDRDDPFWERLRFDQALERVEVPILLLSGWQDLFLDQT
Mflv_4032|M.gilvum_PYR-GCK --ALWFESWLDHPDTDDPFWTRLRLRDGLERAEVPVLLLTGWQDLFVDQT
Mvan_2322|M.vanbaalenii_PYR-1 --APWFESWLEHPETDDPFWSGLRLRDALADVDVPVLLLTGWQDLFVEQT
TH_1432|M.thermoresistible__bu --------------------------------------------------
MAB_2222c|M.abscessus_ATCC_199 RVAPWYFDWIRHSTRDD-YWKRWSIRDRYQNVTVPVLHFEGWYDAFLRGG
Mb2823|M.bovis_AF2122/97 LQQYRHLRDRG------VHVALTVGPWTHTQMLTKG--------------
Rv2800|M.tuberculosis_H37Rv LQQYRHLRDRG------VHVALTVGPWTHTQMLTKG--------------
MMAR_1910|M.marinum_M LQQYRHLRDRG------VDVALTIGPWTHSQLLSKG--------------
MUL_2134|M.ulcerans_Agy99 LQQYRHLRDRG------VDVALTIGPWTHSQLLSKG--------------
MAV_3687|M.avium_104 LQQYAHLRARG------VDVALTVGPWTHTQLLTTG--------------
MSMEG_2644|M.smegmatis_MC2_155 LEQYTQLHRRG------VPVAMTVGPWTHTQMMTKG--------------
Mflv_4032|M.gilvum_PYR-GCK VEHYRMLAGRG------VPTGLTIGPWTHGDMMTKA--------------
Mvan_2322|M.vanbaalenii_PYR-1 LEHYRMLTSRG------VTAGLTVGPWTHGHMMTTA--------------
TH_1432|M.thermoresistible__bu -----------------VPVAMTIGPWTHGHILTRA--------------
MAB_2222c|M.abscessus_ATCC_199 LENFAGMTARGGSPGARRYQRMVIGPWDHLAWGRESSSPSPLLKGLGPGA
:.:*** * .
Mb2823|M.bovis_AF2122/97 LATGARESLDWLDAHLGRAPALR-PSPVRVFVTGQG----WRHLPDWP--
Rv2800|M.tuberculosis_H37Rv LATGARESLDWLDAHLGRAPALR-PSPVRVFVTGQG----WRHLPDWP--
MMAR_1910|M.marinum_M LAVSAQETLDWLDTHLGGTAELRRPDAVRVYVTGEG----WRHLSDWP--
MUL_2134|M.ulcerans_Agy99 LAVSAQETLDWLDTHLGGTAELRRPDAVRVYVTGEG----WRHLSDWP--
MAV_3687|M.avium_104 LGVCTRESLQWLETHLGDAPGRR-AGRVHVYVTGVDRARAWRRLPDWP--
MSMEG_2644|M.smegmatis_MC2_155 ASTVIGESLDWLGTHLAGASGSHSRDHVRIFVNHHG----WIDLPEWPLA
Mflv_4032|M.gilvum_PYR-GCK APTMLRESLDWLATHLKGEPPQR-RSPVRIHLSRRG----WLNLPDWP--
Mvan_2322|M.vanbaalenii_PYR-1 APTVLGETLDWLATHLGGAAPLR-RSPVRIHLGGRG----WLNLPDWP--
TH_1432|M.thermoresistible__bu APRVLRESLAWLDTHLAGTRTAS-RPPVRVHVRRRG----WYDLPDWP--
MAB_2222c|M.abscessus_ATCC_199 NSPVNEMQLAWFDHFLKGSDNGVATESPRLDYYLMG-ANRWKHASAWP--
* *: .* :: . * . **
Mb2823|M.bovis_AF2122/97 --PATTERAWYLQPG------GRLGESAP-ASGTPPAT-FRYHPADPTPT
Rv2800|M.tuberculosis_H37Rv --PATTERAWYLQPG------GRLGESAP-ASGTPPAT-FRYHPADPTPT
MMAR_1910|M.marinum_M --PKTTDHELYLHPT------GRLSEIAP-PDATTPAT-FRYDPTDPTPT
MUL_2134|M.ulcerans_Agy99 --PKTTDHELYLHPT------GRLSEIAP-PDATTPAT-FRYDPTDPTPT
MAV_3687|M.avium_104 --PATTERALYLRPG------GYLGETAPSLKGLAPAT-FRYDPAHPTPT
MSMEG_2644|M.smegmatis_MC2_155 DWPTRRDRELFLQPA------ARLTDSAP-PPTAAPSS-FTYHPARPTPT
Mflv_4032|M.gilvum_PYR-GCK --PAMPSLVLHPQPG------GGLAPGAP--G-AADAT-FVYNPGDPTPT
Mvan_2322|M.vanbaalenii_PYR-1 --PAMPDVVLHPQPA------GRLGPAAP--EPDGTAT-FVYNPADPTPT
TH_1432|M.thermoresistible__bu --PELPAQSWYLRPGRHPRTEACLGTTAPDTGAAAPGWSFTFDPADPTPT
MAB_2222c|M.abscessus_ATCC_199 -LPQTNWTVYHLGGRG----TQHNGTLRDSAAAHDAPDVYLYDPANPVPS
* . : :.* *.*:
Mb2823|M.bovis_AF2122/97 TGGP----LLSSNGGYRDDSRLATRADVLCFTGAPLTHDLCVHGNPVVEL
Rv2800|M.tuberculosis_H37Rv TGGP----LLSSNGGYRDDSRLATRADVLCFTGAPLTHDLCVHGNPVVEL
MMAR_1910|M.marinum_M IGGP----LLSSKAGYRNDSRLASRNDVLTFTGSALTHDLWIHGHPVIEL
MUL_2134|M.ulcerans_Agy99 IGGP----LLSSKAGYRNDSRLASRNDVLTFTGSALTHDLWIHGHPVIEL
MAV_3687|M.avium_104 TGGP----LLSPNGGYRDDTRLASRDDVLAFTSATLTEDVYVYGNPVVEL
MSMEG_2644|M.smegmatis_MC2_155 IGGR----LLSRDGGYRDDSELAARDDVVTFTSDPLPADLYVVGNPFVEL
Mflv_4032|M.gilvum_PYR-GCK VGGR----LLSPVGGYRDDTALARRADVLTFTGTALASDLPVVGVPVLDV
Mvan_2322|M.vanbaalenii_PYR-1 VGGR----LLSPAGGYRDDTALARRADVLTFTGTPLPADLYVVGHPVLEL
TH_1432|M.thermoresistible__bu VGGR----LLSPAGGRRRDDRLARRPDVLSFTSQPLPHALRLLGVPVAEL
MAB_2222c|M.abscessus_ATCC_199 AGGHSCCAAESAPQGRYDQRAVEQRPDVLTYTTEPLSTNTEITGPISVDL
** * * : : * **: :* .*. : * ::
Mb2823|M.bovis_AF2122/97 VHSSDNPYVDVFVRVSEVDAKGRSRNVSDGYRRLGDAP------------
Rv2800|M.tuberculosis_H37Rv VHSSDNPYVDVFVRVSEVDAKGRSRNVSDGYRRLGDAP------------
MMAR_1910|M.marinum_M THSSDNPNVDVFVRISEVDSNGRSRNVSDGYQRLGDAP------------
MUL_2134|M.ulcerans_Agy99 THSSDNPNVDVFVRISEVDSNGRSRNVSDGYQRLGDAP------------
MAV_3687|M.avium_104 AHGADHPHADLFVRVSEVDAAGRSRNVTETYRRLSAAAKPK--------A
MSMEG_2644|M.smegmatis_MC2_155 VHSCDNPHNDVFVRISEVDAKGRSRNVTDAFRRRTGQVG----------T
Mflv_4032|M.gilvum_PYR-GCK AHTCATPHNDLFVRISQVDAHGRSRNVSDGYVASAPDS------------
Mvan_2322|M.vanbaalenii_PYR-1 AHTCANPHNDLFVRVSQVDEHGRSRNVSDGYLAAAPDS------------
TH_1432|M.thermoresistible__bu VHSCDNPHHDLFVRISEVDRRGRSVNVSDGFRRCHREAG----------S
MAB_2222c|M.abscessus_ATCC_199 WASSSAPDTDFTAKLVAVQADGTAANLNNGIVRTSLAQSLSERRLMPIGQ
. * *. .:: *: * : *:.:
Mb2823|M.bovis_AF2122/97 -ELVRVELDAIAHRFRADSRIRVLIAGSWFPRYARNLGTPEPILTGRQLK
Rv2800|M.tuberculosis_H37Rv -ELVRVELDAIAHRFRADSRIRVLIAGSWFPRYARNLGTPEPILTGRQLK
MMAR_1910|M.marinum_M -ETVRIELDPIAHRFKAGSRIRVLIAGSWFPRYARHLGTDEPTLTGRQVQ
MUL_2134|M.ulcerans_Agy99 -ETVRIELDPIAHRFKAGSRIRVLVAGSWFPRYARHLGTDEPTLTGRQVQ
MAV_3687|M.avium_104 DKVIRLELDGTAHRFRAGSRIRLLIAGSWSPRYAHNLGSGEPVLTARRLT
MSMEG_2644|M.smegmatis_MC2_155 PETVRLELDAVAHRFAAGTRIRLLVAGGSHPRFARNLGTGEPQPSGSRLK
Mflv_4032|M.gilvum_PYR-GCK -GTVTVELDPVAWTFPAGSRIRVLIAGGSHPRFLRNLGTGEHAGTATDFA
Mvan_2322|M.vanbaalenii_PYR-1 -GTARIELDPVAWTFPAGSRIRLLIAGGSHPRFLRNLGTGETATTATTYK
TH_1432|M.thermoresistible__bu IGTVRLELDAVGHTFRAGHRIRVLIAGGSHPRFTRNLGTGEPPVSGRRMT
MAB_2222c|M.abscessus_ATCC_199 PHKYHIDIWPVSYQFRTGERIRLEISSSDFPQYAPNPNTAAPFGRNAELR
::: . * :. ***: ::.. *:: : .:
Mb2823|M.bovis_AF2122/97 PATHAVHFGR---SRLLLPVG----------------------
Rv2800|M.tuberculosis_H37Rv PATHAVHFGR---SRLLLPVG----------------------
MMAR_1910|M.marinum_M PATHSVYFGQ---SRLLLGVDQSANDITDAGSDESPE------
MUL_2134|M.ulcerans_Agy99 PATHSVYFGQ---SRLLLGVDQSANDITDAGSDESPE------
MAV_3687|M.avium_104 PVTHSVRYGR---SRLLLPVGPAEPSADGVADPVGDGG-----
MSMEG_2644|M.smegmatis_MC2_155 QARHSVHHGDGGVSRLILPAGPTPPLGLRT-------------
Mflv_4032|M.gilvum_PYR-GCK TARHTVHLGEG--TRLTLPAGPPPPSAD---------------
Mvan_2322|M.vanbaalenii_PYR-1 TARHTVHLGEQ--SRLVLPAGSHPPSTD---------------
TH_1432|M.thermoresistible__bu PATHTVHPGT----RVLLPADTEPPDPGSGFPSGH--------
MAB_2222c|M.abscessus_ATCC_199 TATQIILHDAAHPSTLTLPVIPAGDPGTETFPMPRRPDDPPGN
. : : . : * .