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M. abscessus ATCC 19977 MAB_3826c (-)

annotation: acetyl-CoA acetyltransferase
coordinates: 3871370 - 3872872
length: 500

AFDPRTPVLVGTGQVNQRTDADTPFSEIPEPIDLMEQAARLAAGDAGATELLGAIDTISVANIFSWRYRD
PGVLLGERLGAVPKRTFYTGPSGNSPQLLVNHAAADILAGDADVVLIGGAEMWRSRNKMMATGVQPTWTI
QDESVAEATVLGGRMDQVGGAETAIGLISPGHVYPLFEEAIRIAGGVSIADHRAAMSQLWQRFNAVAVTN
GHAWSNDAYTAEEIATPGPDNRWISSPYTKLMNSNNMVEQGAVVLLTSVETALRLGISKDRWIFPLAGAQ
ANDTFALSERHELHRSPAIRLAGRRAFEIAGLGTDDVELVDIYSCFPSAVQVAAAELGLALDDPARPLTV
TGGLTFAGGPWCNYVTHSIATMAERLRERPGAKGLITANGGYLTKHAFGIYGTEPPASGFAYEDVQADVD
QEPRTEAADGYTGTAAVEAWTVNYGRDGSPFQTFVSVRTPTGARTFAKIDDRDASAHIADTDIAGASIEV
AADGSARLN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3826c--100% (500)acetyl-CoA acetyltransferase
M. abscessus ATCC 19977MAB_2042c-2e-7336.44% (505) acetyl-CoA acetyltransferase
M. abscessus ATCC 19977MAB_0378-2e-0625.95% (158) lipid-transfer protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1898-1e-15657.31% (499) acetyl-CoA acetyltransferase
M. gilvum PYR-GCKMflv_3340-1e-15957.52% (499) acetyl-CoA acetyltransferase
M. tuberculosis H37RvRv1867-1e-15657.31% (499) acetyl-CoA acetyltransferase
M. leprae Br4923-----
M. marinum MMMAR_2746-1e-15957.52% (499) hypothetical protein MMAR_2746
M. avium 104MAV_2851-1e-16158.52% (499) acetyl-CoA acetyltransferase
M. smegmatis MC2 155MSMEG_3608-1e-16258.30% (494) acetyl-CoA acetyltransferase
M. thermoresistible (build 8)TH_1434-1e-11860.95% (338) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_3008-1e-15657.60% (500) acetyl-CoA acetyltransferase
M. vanbaalenii PYR-1Mvan_3068-1e-15856.71% (499) acetyl-CoA acetyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1898|M.bovis_AF2122/97            MPVDPRTPVLIGYGQVNHRGDIDAEK-QSIEPVDLMAAAARKAADST---
Rv1867|M.tuberculosis_H37Rv         MPVDPRTPVLIGYGQVNHRGDIDAEK-QSIEPVDLMAAAARKAADST---
MMAR_2746|M.marinum_M               MVVDPRTPVLIGYGQVNYRDEIDPTM-PSVEPVDLMLAAAQQAADSR---
MUL_3008|M.ulcerans_Agy99           MAVDPRTPVLIGYGQVNYRDEIDPTM-PSVEPVDLMLAAAQQAADSR---
MAV_2851|M.avium_104                MTVDPRTPVLIGYGQVNHRDDIDPAV-RSVEPVDLMAAAVERAADAA---
Mflv_3340|M.gilvum_PYR-GCK          MPIDPRTPVLIGYGQVNQRTED-----PSVEPVDLMAAAAREAADPR---
Mvan_3068|M.vanbaalenii_PYR-1       MPIDPRTPVLVGYGQVNQHDEN-----PDVEPVDLMVQAARAAADPR---
MSMEG_3608|M.smegmatis_MC2_155      --MN-RTPVLVGYGQVSQYDEN-----PATEPVDLMAEAARNAADPR---
TH_1434|M.thermoresistible__bu      --------------------------------------------------
MAB_3826c|M.abscessus_ATCC_199      MAFDPRTPVLVGTGQVNQRTDADTPFSEIPEPIDLMEQAARLAAGDAGAT
                                                                                      

Mb1898|M.bovis_AF2122/97            -VLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSL
Rv1867|M.tuberculosis_H37Rv         -VLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSL
MMAR_2746|M.marinum_M               -VLAAVDSIRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQSL
MUL_3008|M.ulcerans_Agy99           -VLAAVDSMRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQPL
MAV_2851|M.avium_104                -VIEAVDSIRVVNILSAQYRDPGLLLGQRIGARDFGTLYTPVGGNVPQSL
Mflv_3340|M.gilvum_PYR-GCK          -VLEAVDAVRVVNLLSWRYRDPGLLLAERIGAAKAATRYTGIGGNVPQTL
Mvan_3068|M.vanbaalenii_PYR-1       -LLEAVDAVRVVNLLSWRYRDPGLLLAQRIRADKAVTRYTGIGGNVPQTL
MSMEG_3608|M.smegmatis_MC2_155      -VLQAVDSVRVVNLLSWRYRDPGLLLAGRIGAAGARTRYTGIGGNVPQTL
TH_1434|M.thermoresistible__bu      --------------------------------------------------
MAB_3826c|M.abscessus_ATCC_199      ELLGAIDTISVANIFSWRYRDPGVLLGERLGAVPKRTFYTGPSGNSPQLL
                                                                                      

Mb1898|M.bovis_AF2122/97            VNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPD
Rv1867|M.tuberculosis_H37Rv         VNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPD
MMAR_2746|M.marinum_M               VSQACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPR
MUL_3008|M.ulcerans_Agy99           VSQACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPR
MAV_2851|M.avium_104                VNQACLDIQRGRANVVLLAGAETWRTRRGLRAKGGKLVWTEQDRSVPMAE
Mflv_3340|M.gilvum_PYR-GCK          VNLACLDIQQGRNDVVLIAGAETWRSRTRTRAAGNKMQGTRQDESVPMAP
Mvan_3068|M.vanbaalenii_PYR-1       VNMACLDIQQGKADVVLIAGAETWRTRSRIRAAGRRPDWTKQDESVPSAP
MSMEG_3608|M.smegmatis_MC2_155      VNHACLDLQAGRAEVVLIAGAETWRTRSRLRARGVRPDWTRQDDTVPVAP
TH_1434|M.thermoresistible__bu      --------------------------------------------------
MAB_3826c|M.abscessus_ATCC_199      VNHAAADILAGDADVVLIGGAEMWRSRNKMMATGVQPTWTIQDESVAEAT
                                                                                      

Mb1898|M.bovis_AF2122/97            MAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGEL
Rv1867|M.tuberculosis_H37Rv         MAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGEL
MMAR_2746|M.marinum_M               VAGQDVPMAGESEIRIKLDRPAYVYPIFEQALRIANGESIEDHRSRVGRL
MUL_3008|M.ulcerans_Agy99           VAGQDVPMAGESEIRIKLDRAAYVYPMFEQALRIANGESIEDHRSRVGRL
MAV_2851|M.avium_104                VSGEDVAMAGEAEIRISLDRPAYVYPLFEQALRVSTGESVEDHLTRIGRL
Mflv_3340|M.gilvum_PYR-GCK          GSDENMPMAGPGDLKIGLDRPAYVYPMFETAVRIAAGETPDEHRRRIGEL
Mvan_3068|M.vanbaalenii_PYR-1       GGDESVPMAAPSDIRINLDRPAYVYPMFEQALRIAAGETPDEHRRRIGEL
MSMEG_3608|M.smegmatis_MC2_155      GGDDNVPMAGDAENRIKLDRPAFVYPMFEQALRIAAGETPDEHRDRIGAL
TH_1434|M.thermoresistible__bu      -------MATPADIRIQLDRPSYVYPLFEQALRITAGEHPDAHRRRIGEL
MAB_3826c|M.abscessus_ATCC_199      VLGGRMDQVGGAETAIGLISPGHVYPLFEEAIRIAGGVSIADHRAAMSQL
                                            .  .:  * *  ...***:** *:*:: *     *   :. *

Mb1898|M.bovis_AF2122/97            WARFSAVAADNPHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVD
Rv1867|M.tuberculosis_H37Rv         WARFSAVAADNPHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVD
MMAR_2746|M.marinum_M               WAGFNAVAVDNPHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMVD
MUL_3008|M.ulcerans_Agy99           WAGFNAVAVDNPHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMVD
MAV_2851|M.avium_104                WARFNAVAVDNPHAWIRTPHSADDICRAGPHNRMISWPYTKLMNSNNMVD
Mflv_3340|M.gilvum_PYR-GCK          WAQFSAVAAGNPHAWSQEARTAEEIYEPSPKNRMVSWPYTKLMNSNNMVD
Mvan_3068|M.vanbaalenii_PYR-1       WAQFSAVAADNPHAWNREALTPEQIWQPSASNRMISWPYTKLMNSNNMVD
MSMEG_3608|M.smegmatis_MC2_155      WSRFSAVAARNPHAWNRDAVTAQQITQVGPDNRMISWPYPKLMNSNNMVD
TH_1434|M.thermoresistible__bu      WARFSAVAADNPHAWNRKALSAEQIWRPGPDNRMISWPYPKLMNSNNMVD
MAB_3826c|M.abscessus_ATCC_199      WQRFNAVAVTNGHAWSNDAYTAEEIATPGPDNRWISSPYTKLMNSNNMVE
                                    *  *.***. * *** . . :.::*   .. ** :* **.*********:

Mb1898|M.bovis_AF2122/97            QGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAI
Rv1867|M.tuberculosis_H37Rv         QGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAI
MMAR_2746|M.marinum_M               QGAALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSIAERAELHQSPAI
MUL_3008|M.ulcerans_Agy99           QGAALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSSAERAELHQSPAI
MAV_2851|M.avium_104                QGAALVLTSVEQARRLKVPPERWVYPLAGTDAHDTASIAERHELHRSAAI
Mflv_3340|M.gilvum_PYR-GCK          QGAVLILTSVEKAQHLQIPSERWVFPYAGADAHDTYAIGERAEFHASPAI
Mvan_3068|M.vanbaalenii_PYR-1       QGAVLIVASAETARHLQIPSDRWVFPYAGADSHDTYAIAERAEFHTSPAI
MSMEG_3608|M.smegmatis_MC2_155      QGAVLILTTVQMATYLQIPMDRWVFPYAGTDSHDTYAIGERDELHRSPAI
TH_1434|M.thermoresistible__bu      QGAALILTSVQRARELRIPSERWVFPYAGTDAHDTYAIGERYRLDRSPAI
MAB_3826c|M.abscessus_ATCC_199      QGAVVLLTSVETALRLGISKDRWIFPLAGAQANDTFALSERHELHRSPAI
                                    ***.:::::.: *  * :. :**::* :*::::** : .:* .:. *.**

Mb1898|M.bovis_AF2122/97            RIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLT
Rv1867|M.tuberculosis_H37Rv         RIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLT
MMAR_2746|M.marinum_M               RIAGARALELAGLGIDDADYVDLYSCFPSAVQVAAHELGLPVDDADRPLT
MUL_3008|M.ulcerans_Agy99           RIAGARALELAGLGINDADYVDLYSCFPSAVQVAAHELGLPVDDADRPLT
MAV_2851|M.avium_104                RIAGARALQLAGLGIDDVDHVDLYSCFPSAVQVAAAELGLGLDDPARPLT
Mflv_3340|M.gilvum_PYR-GCK          RIAGTRALELAGAGVDDMDLIDVYSCFPSAVQVAARELGLPIGDPDRPLT
Mvan_3068|M.vanbaalenii_PYR-1       RIAGRRALELAGAGVDDMDLVDVYSCFPSAVQVAARELGLPVGKPDRPLT
MSMEG_3608|M.smegmatis_MC2_155      RIAGRRVLELAGADIDAIDFVDVYSCFPSAVQVAAAELGLPTDDPARPLT
TH_1434|M.thermoresistible__bu      RIAGRRVLELAGLGIDDFRFVDVYSCFPSAVQVAAIELGLPLDDPARPLT
MAB_3826c|M.abscessus_ATCC_199      RLAGRRAFEIAGLGTDDVELVDIYSCFPSAVQVAAAELGLALDDPARPLT
                                    *:** *.:::** . :    :*:************ ****  ... ****

Mb1898|M.bovis_AF2122/97            VTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFG
Rv1867|M.tuberculosis_H37Rv         VTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFG
MMAR_2746|M.marinum_M               VTGGLTFAGGPWNNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSIG
MUL_3008|M.ulcerans_Agy99           VTGGLTFAGGPWDNYVTHSIATMAELLAANPGRRGLITANGGYLTQHSIG
MAV_2851|M.avium_104                VTGGLTFAGGPWSNYVMHSIATMAELLVANPGRRGLITANGGYLTKHSFG
Mflv_3340|M.gilvum_PYR-GCK          VTGGLTFAGGPWNNYVTHSIATMAEQLIARPGTRGLITANGGYLTKHSFG
Mvan_3068|M.vanbaalenii_PYR-1       VTGGLTFAGGPWNNYVTHSIATMAERLAAQPGQRGLITANGGYLTKHSFG
MSMEG_3608|M.smegmatis_MC2_155      VTGGLTFAGGPWNNYVTHSIATMAEKLVAEPGTRGLITANGGYLTKHSFG
TH_1434|M.thermoresistible__bu      VTGGLTFAGGPWNNYVTHAIATMAERLIAAPGSRGLVTANGGYLTKHAFG
MAB_3826c|M.abscessus_ATCC_199      VTGGLTFAGGPWCNYVTHSIATMAERLRERPGAKGLITANGGYLTKHAFG
                                    ************ *** *:****** *   ** :**:********:*::*

Mb1898|M.bovis_AF2122/97            VYGTEPPS-EFRWEDMQPAVDREPTGDGLVEWEGIGTVEAWTTPVNRDGQ
Rv1867|M.tuberculosis_H37Rv         VYGTEPPS-EFRWEDMQPAVDREPTGDGLVEWEGIGTVEAWTTPVNRDGQ
MMAR_2746|M.marinum_M               VYGTEPPA-EFCWEDVQPLVDREPTRAALVGWDGVGAVEAWTTPFTRDGQ
MUL_3008|M.ulcerans_Agy99           VYGTEPPA-EFRWEDVQPLVDREPTRAALVGWDGVGAVEAWTTPFTRDGQ
MAV_2851|M.avium_104                VYGTEPPA-EFRWEDTQSAVDREPTTDAAVEWEGVGTVEAWTTPHDREGE
Mflv_3340|M.gilvum_PYR-GCK          VYGTEPPTHEFRWEDVQSEVDAEPTRTALVDWSGVGTVETWTTPVDRDGN
Mvan_3068|M.vanbaalenii_PYR-1       VYGTEPPKHEFRWEDVQSEVDREPTRTAVVEWSGVGTVESWTTPVDRDGA
MSMEG_3608|M.smegmatis_MC2_155      VYGTEPPEQEFRWEDVQSVVDAEPTRKLAVEWVGTGTVESWTTPFNRDGA
TH_1434|M.thermoresistible__bu      VYSTEPPPVEFRWEDVQSEVDREPVRKVLVEWSGTGTVESWTTPFDRDGN
MAB_3826c|M.abscessus_ATCC_199      IYGTEPPASGFAYEDVQADVDQEPRTEAADGYTGTAAVEAWTVNYGRDGS
                                    :*.****   * :** *. ** **       : * .:**:**.   *:* 

Mb1898|M.bovis_AF2122/97            PEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTATLR
Rv1867|M.tuberculosis_H37Rv         PEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTATLR
MMAR_2746|M.marinum_M               PEKAFVAVRTPTGARTLGVITDPASANATVHEDIAGAKVAIAADGNATLR
MUL_3008|M.ulcerans_Agy99           PEKAFVAVRTPTGARTLGVITDPASAHATVHEDIAGAKVAIAADGNATLR
MAV_2851|M.avium_104                PEKAFLAVRTPDGSRALAVVTDRAAAQATVREDIGGAKVAVAADGSAALQ
Mflv_3340|M.gilvum_PYR-GCK          PEKAFLAVRTPEDARVLAVITDPAGAETTVRDDIAGAQVRVEEDGTASLV
Mvan_3068|M.vanbaalenii_PYR-1       PEKAFLAVRTPEDARVLAVITDRAGAEATVRDDIAGAAVRVHADGTASLE
MSMEG_3608|M.smegmatis_MC2_155      PEKAFLAVRTPDGARTLAVITDESQAAATVREDIAGARVEVHADGTATLL
TH_1434|M.thermoresistible__bu      PEKAFVAVRTPEDSRALAVIIDPSAAAVTVSEDVAGAPIRVHADGTATLG
MAB_3826c|M.abscessus_ATCC_199      PFQTFVSVRTPTGARTFAKIDDRDASAHIADTDIAGASIEVAADGSARLN
                                    * ::*::**** .:* :. : *       .  *:.*. : :  **.* *