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TDFVAPEWGSSALVIIDVQTEFVSGAMTVPGTADRIPALARLASAFRKAGRPIVHVVRLYVPGGSDTDLP RRAEILAGREIAAPGTDGSQIPHELLPTGAQLDSALLLAGGFQEVGPAEHILFKPRWSAFYRTELEQHLR ERGISTVVVAGCNLPNCPRATLFDASERDYRAVVVEDATSQVTPERLHDLRLIGVNISDVASVEKELTGA *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1852c | - | - | 100% (211) | isochorismatase hydrolase |
| M. abscessus ATCC 19977 | MAB_3431c | - | 4e-10 | 28.26% (184) | isochorismatase hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2069c | pncA | 4e-05 | 26.47% (204) | pyrazinamidase/nicotinamidas PNCA (PZase) |
| M. gilvum PYR-GCK | Mflv_1089 | - | 4e-06 | 27.13% (188) | isochorismatase hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3790 | - | 5e-07 | 24.62% (195) | isochorismatase family protein |
| M. avium 104 | MAV_5193 | - | 1e-54 | 51.67% (209) | isochorismatase family protein |
| M. smegmatis MC2 155 | MSMEG_4976 | - | 3e-07 | 28.82% (170) | isochorismatase hydrolase |
| M. thermoresistible (build 8) | TH_1796 | pncA | 4e-06 | 27.27% (209) | PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZase) |
| M. ulcerans Agy99 | MUL_2257 | pncA | 2e-05 | 27.54% (207) | pyrazinamidase/nicotinamidase, PncA |
| M. vanbaalenii PYR-1 | Mvan_3053 | - | 4e-12 | 27.51% (189) | isochorismatase hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1852c|M.abscessus_ATCC_199 -----------------------MTDFVAPEWG---------------SS
MAV_5193|M.avium_104 MLSADHRFQQTMTVRFGRRGRVPITGWVQSRRGVGMAGEDHYTRPCADSA
Mb2069c|M.bovis_AF2122/97 ------------------------------------------------MR
MUL_2257|M.ulcerans_Agy99 ------------------------------------------------MR
Mflv_1089|M.gilvum_PYR-GCK ------------------------------------------MSTPATTR
TH_1796|M.thermoresistible__bu ------------------------------------------------MT
MSMEG_4976|M.smegmatis_MC2_155 ----------------------------MTRPTLREISSLPAEPVRLADS
Mvan_3053|M.vanbaalenii_PYR-1 -----------------------------MNHTVDVPAEPSSFPLVAGRT
MMAR_3790|M.marinum_M ----MPEYFSDTSRWTCSPEHVDLDIPRRFTRRVRLAAQPQHVTLDLGDA
MAB_1852c|M.abscessus_ATCC_199 ALVIIDVQTEFVSG----AMTVPGTADRIPALARLAS---AFRKAGRPIV
MAV_5193|M.avium_104 ALVLIDVQRDFYADD--APMRVEGTSAALGAMAELAR---AFRRRELPIV
Mb2069c|M.bovis_AF2122/97 ALIIVDVQNDFCEG---GSLAVTGGAALARAISDYLA-----EAADYHHV
MUL_2257|M.ulcerans_Agy99 ALVIVDLQNDFCAG---GALPGQNADLVARAINDYLA-----GSPGYDRV
Mflv_1089|M.gilvum_PYR-GCK ALVIVDVQNDFCEG---GSLAVDGGAAVARGISTLLGSLGIDGSHSYHHV
TH_1796|M.thermoresistible__bu ALIIVDVQNDFCEG---GALAVAGGATTARRISDLLR-----SETGYTHV
MSMEG_4976|M.smegmatis_MC2_155 ALVLIDCQNTYTRG----VMELEGVQAALDATAELLD------RARTAGI
Mvan_3053|M.vanbaalenii_PYR-1 ALIVIDMQRDFLLPGGFGESLGNDVGRLLKVVPPLASLIAAARAAGVMVV
MMAR_3790|M.marinum_M AVIVVDMQNDFCHERGWLASQGVDVRGGAGLKTPINAMLDGFRGAQVPII
*::::* * : . :
MAB_1852c|M.abscessus_ATCC_199 HVVRLYVPGGSDTDLPRRAEILAGREIAAPGTDGSQIPHELLPTGAQLDS
MAV_5193|M.avium_104 HVVRLYRADGSNADPVRRRFIEDGARVAEPGSPGSQIAPELLPKAVELDH
Mb2069c|M.bovis_AF2122/97 VATKDFHIDPGDDFSGTPDYSSSWPPHCVSGTPGADFHPSLDTSAIEA--
MUL_2257|M.ulcerans_Agy99 VAAQDFHIDPGAHFSDCPDYSSSWPPHCRAGSTGAQFCPDLDVAPIEA--
Mflv_1089|M.gilvum_PYR-GCK VATKDFHIDPGAHFSDQPDYVDSWPVHCVAGSEGAEFHPDLDTAAVEA--
TH_1796|M.thermoresistible__bu VATKDQHIDPGDHFSDHPDFVRSWPRHCVAGTPGAEFHPDLDTGRIEA--
MSMEG_4976|M.smegmatis_MC2_155 PIIHIQHDSGPGSPYDVREEIGAIVESVAPRGDEPVVVKNFPNSFVQT--
Mvan_3053|M.vanbaalenii_PYR-1 HTREGHQPDLSDCPPAKLNRGTPSKRIGDPGRYGRILIRGEYGHDIID--
MMAR_3790|M.marinum_M WLNWGTRSDRANLPPNVLHAYDGEGTGGGIGESVSLLSNAVLTANSWG--
. .
MAB_1852c|M.abscessus_ATCC_199 ALLLAGGFQEVGPAEHILFKPRWSAFYRTELEQHLRERGISTVVVAGCNL
MAV_5193|M.avium_104 QLLLSGGFQQIGPAEHVMYKPRWGAFYGTKLEQHLRESGTDTLVFAGCNF
Mb2069c|M.bovis_AF2122/97 -VFYKGAYTGAYSGFEGVDEN------GTPLLNWLRQRGVDEVDVVGIAT
MUL_2257|M.ulcerans_Agy99 -VFRKGAYCAAYSGFEGVDHH------GTTLEDWLRQRSIDAVDVVGVAT
Mflv_1089|M.gilvum_PYR-GCK -VFYKGHYSAAYSGFEGTDDD------GTSLADWLRERNVAAVDVVGIAT
TH_1796|M.thermoresistible__bu -VFGKGQYSDGYSGFEGVDES------GTPLAQWLRDHGVTRVDIVGIAT
MSMEG_4976|M.smegmatis_MC2_155 ---------DLQQRLQAVNAS------NLVLAGFMTHMCVNSTARGAFNL
Mvan_3053|M.vanbaalenii_PYR-1 -------ELAPIDGEIVIDKPGKGAFYATSLSDVLTEAGITQLLITGVTT
MMAR_3790|M.marinum_M --AAILDGLVVDDIDIHVNKHRMSGFWDTELDSILRNLGVRHLFLCGVNV
* : . .
MAB_1852c|M.abscessus_ATCC_199 PNCPRATLFDASERDYRAV--VVEDATSQVTPER--------LHDLRLIG
MAV_5193|M.avium_104 PNCPRTSIYEASERDFRIV--LVTDAISGLYDRG--------AQECRAIG
Mb2069c|M.bovis_AF2122/97 DHCVRQTAEDAVRNGLATR--VLVDLTAGVSAD---------TTVAALEE
MUL_2257|M.ulcerans_Agy99 DHCVRQTAEGAARAGFATR--VLLDLTAGISAE---------TTEVALAG
Mflv_1089|M.gilvum_PYR-GCK DHCVKATAADAATAGFATR--VLLDLTAGVSPS---------TTGAAIGA
TH_1796|M.thermoresistible__bu DHCVRATALDAVRHGFDTR--VLVDYTAGVDAD---------ATARAVSE
MSMEG_4976|M.smegmatis_MC2_155 GFAPTVVAAATATRSLPGPDGNLVPASAMQSASL--------AAIADLFA
Mvan_3053|M.vanbaalenii_PYR-1 EVCVHTTTREANDRGYQCL--VVSDCVGSYFPEFQRVGLEMIKAQGGIFG
MMAR_3790|M.marinum_M DQCVYATLIDAACAGYDCL--LITDASATTSPSYCTEAT--IYNVRQCFG
. : . : .
MAB_1852c|M.abscessus_ATCC_199 VNISDVASVEKELTGA------------
MAV_5193|M.avium_104 VAVRDTAQTLDWLGG-------------
Mb2069c|M.bovis_AF2122/97 MRTASVELVCSS----------------
MUL_2257|M.ulcerans_Agy99 MRTAGVALVGSR----------------
Mflv_1089|M.gilvum_PYR-GCK LRAAGVVILP------------------
TH_1796|M.thermoresistible__bu LRDAGVAVTGSLAA--------------
MSMEG_4976|M.smegmatis_MC2_155 VVVPDVGSIPD-----------------
Mvan_3053|M.vanbaalenii_PYR-1 WVADTSSVIPALARLSSIPA--------
MMAR_3790|M.marinum_M FTCDTAAIRASLHAPTEPHGVCGTCQPE