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M. abscessus ATCC 19977 MAB_1528c (-)

annotation: oxidoreductase
coordinates: 1548465 - 1549280
length: 271

TLNSGTTIPQLGYGVWQVPDDQARAAVSAALQVGYRSIDTAKIYDNEAGTGAAIAESGIPRGDVFLTTKL
WNSDQGYDNALRAFDASLERLGTDYVDLYLIHWPVPELDEYVASFKALQRIQADGRAKAIGVSNFTVDNL
KRLIDETGEVPALNQIELHPRFTQPELRAFHAEYGIATEAWSPLGQGTILEDATIGAIAQAHDVSAAQVI
LRWHLQLGNVVIPKSVTPARIAANFDVFGFELSTDEVERITALDASDGRIGPDPTTFNLH*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_1528c--100% (271)oxidoreductase
M. abscessus ATCC 19977MAB_2941-1e-6946.52% (273) putative oxidoreductase
M. abscessus ATCC 19977MAB_4120c-7e-1327.34% (278) aldo/keto reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2996-2e-6948.33% (269) oxidoreductase
M. gilvum PYR-GCKMflv_4697-1e-7852.21% (272) 2,5-didehydrogluconate reductase
M. tuberculosis H37RvRv2971-5e-7048.70% (269) oxidoreductase
M. leprae Br4923MLBr_01669-2e-6746.84% (269) putative oxidoreductase of Aldo/keto reductase family
M. marinum MMMAR_1744-7e-6546.84% (269) oxidoreductase
M. avium 104MAV_1085-2e-7650.74% (272) morphine 6-dehydrogenase
M. smegmatis MC2 155MSMEG_2408-1e-9561.71% (269) 2,5-diketo-D-gluconic acid reductase A
M. thermoresistible (build 8)TH_1525-5e-7549.45% (273) 2,5-diketo-D-gluconic acid reductase A
M. ulcerans Agy99MUL_1987-1e-6446.10% (269) oxidoreductase
M. vanbaalenii PYR-1Mvan_1769-1e-8053.31% (272) 2,5-didehydrogluconate reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4697|M.gilvum_PYR-GCK          ------MTHVPAIELNDGASIPQLGFGVYQISPEDTADVVRQALEVGYRH
Mvan_1769|M.vanbaalenii_PYR-1       ------MSNTPTIELNDGTGIPQLGFGVFQIPPDDTAAAVRSALEIGYRH
MAV_1085|M.avium_104                ------MSKVPTIELNDGARIPQLGFGVYQIKPDETAAAVRAALDIGYRH
TH_1525|M.thermoresistible__bu      ----VNMTTVPAITLNNGAQIPQVGFGVYQIPPDQTAAAVRTALDAGYRH
MAB_1528c|M.abscessus_ATCC_199      ------------MTLNSGTTIPQLGYGVWQVPDDQARAAVSAALQVGYRS
MSMEG_2408|M.smegmatis_MC2_155      ------MS--PRITLNDGNSIPQVGLGVWQTPAEDTERAVAAALQAGYRH
Mb2996|M.bovis_AF2122/97            MTGESGAAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRL
Rv2971|M.tuberculosis_H37Rv         MTGESGAAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRL
MLBr_01669|M.leprae_Br4923          MMPSTPRTSIPSITLNDENTMPLLGLGVAELSEDETERAVLAALEIGCRL
MMAR_1744|M.marinum_M               -MPGAPSPSAPSIALNDENTMPVLGMGVAGLSDDETERAVSAALEIGCRL
MUL_1987|M.ulcerans_Agy99           MMPGAPSPSAPSIALNDENTMPVLGMGVAGLSDDETERAVSAALEIGCRL
                                                : **.   :* :* **     :::  .*  **: * * 

Mflv_4697|M.gilvum_PYR-GCK          IDTAQMYQNEKGVGQGIRNSGIDRGDVFVTSKLNNGFHTPEDARRAFDET
Mvan_1769|M.vanbaalenii_PYR-1       IDTAEMYQNERGVGQGIRDAGIDRAEVYVTSKLNNGFHKPDDARRAFDAT
MAV_1085|M.avium_104                IDTAEMYGNEREVAQGIRDAGLDRSEVFVTSKLNNGFHEPDAARRAFDAT
TH_1525|M.thermoresistible__bu      IDTAQMYGNERGVAEGIRDAGLDRGEVFITSKLNNPYHRPDDARRAFDRT
MAB_1528c|M.abscessus_ATCC_199      IDTAKIYDNEAGTGAAIAESGIPRGDVFLTTKLWNSDQGYDNALRAFDAS
MSMEG_2408|M.smegmatis_MC2_155      IDTAAAYRNETETGRAIANSGVPREDIFLVTKLWNSDQGYDATLAAFDAS
Mb2996|M.bovis_AF2122/97            IDTAYAYGNEAAVGRAIAASGVAREELFVTTKLATPDQGFTRSQEACRAS
Rv2971|M.tuberculosis_H37Rv         IDTAYAYGNEAAVGRAIAASGVAREELFVTTKLATPDQGFTRSQEACRAS
MLBr_01669|M.leprae_Br4923          IDTAAAYGNEAAVSRAIAASGIPRAQLFVTTKLATPDQGFTKSQDACNAS
MMAR_1744|M.marinum_M               IDTAAAYGNEAAVGRAIAASGIPRAELFVTTKVATADHGFTASREACKAS
MUL_1987|M.ulcerans_Agy99           IDTAAAYGNEAAVGRALAASGIPRAELFVTTKVATADHGFTASREACKAS
                                    ****  * **  .. .:  :*: * ::::.:*: .  :    :  *   :

Mflv_4697|M.gilvum_PYR-GCK          LKALEFDYVDLFLIHWPLPTLYDGDFVSTWKTLEEFTKDGRARSIGVSNF
Mvan_1769|M.vanbaalenii_PYR-1       LKALDFDYVDLFLIHWPLPTLYDGDFVSTWKTLEEFKKDGRARSIGVSNF
MAV_1085|M.avium_104                LKALGSDYVDLFLIHWPLPTLYGGDFVSTWRVLEEFARDGRARSIGVSNF
TH_1525|M.thermoresistible__bu      LTELGSDYVDLFLIHWPLPMHYDGDFVSTWKTLEEFAADGRARSIGVSNF
MAB_1528c|M.abscessus_ATCC_199      LERLGTDYVDLYLIHWPVPELD--EYVASFKALQRIQADGRAKAIGVSNF
MSMEG_2408|M.smegmatis_MC2_155      VQRLGVDYLDLYLIHWPVPENN--KFVDTFKAFAHLRDQGRIRSIGVSNF
Mb2996|M.bovis_AF2122/97            LDRLGLDYVDLYLIHWPAPPVG--KYVDAWGGMIQSRGEGHARSIGVSNF
Rv2971|M.tuberculosis_H37Rv         LDRLGLDYVDLYLIHWPAPPVG--KYVDAWGGMIQSRGEGHARSIGVSNF
MLBr_01669|M.leprae_Br4923          LDRLGMDYVDLYLIHWPAPPVG--QYVDAWGGMIQSRGEGHARSIGVCNF
MMAR_1744|M.marinum_M               LDRLGLDYVDLYLIHWPAPAAG--KYVDAFGGLIQARGEGFTRSIGVSNF
MUL_1987|M.ulcerans_Agy99           LDRLGLDYVDLYLIHWPAPAVG--KYVDAFGGLIQARGEGFTRSIGVSNF
                                    :  *  **:**:***** *     .:* ::  : .   :*  ::***.**

Mflv_4697|M.gilvum_PYR-GCK          QVAHLQRLADETDTVPAVNQIEVHPYFANDEVRAYGTEHGIATEAWSPIA
Mvan_1769|M.vanbaalenii_PYR-1       QVAHLQRLAEETDTVPAVNQIEVHPYFANDEVRAYGREHGIATEAWSPIA
MAV_1085|M.avium_104                QVPHLERLATETDTVPAVNQVEVHPYFTNEKVRGYAREHGIAIEAWSPIA
TH_1525|M.thermoresistible__bu      EPAHLDLLAAETSTVPAVNQVEIHPYFGNNDVRRYCAEHGIAVEAWAPIA
MAB_1528c|M.abscessus_ATCC_199      TVDNLKRLIDETGEVPALNQIELHPRFTQPELRAFHAEYGIATEAWSPLG
MSMEG_2408|M.smegmatis_MC2_155      EPEHLTTLIEETGIVPAVNQIELHPLLPQQELRDVHAKLGIATEAWSPLG
Mb2996|M.bovis_AF2122/97            TAEHIENLIDLTFVTPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLA
Rv2971|M.tuberculosis_H37Rv         TAENIENLIDLTFVTPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLA
MLBr_01669|M.leprae_Br4923          TEEHLSAIIDLTFVTPAVNQIELHPLLNQDEMRKSNAQHNVITQSYTPLV
MMAR_1744|M.marinum_M               TEEHVSNVIDLTFVTPAVNQVELHPLLNQDELRKANAQHNVVTQSYTPLA
MUL_1987|M.ulcerans_Agy99           TEEHVSNVIDLTFVTPAVNQVELHPLLNQDELRKANAQHNVVTQSYTPLA
                                       ::  :   *  .**:**:*:** : : .:*    :  :  ::: *: 

Mflv_4697|M.gilvum_PYR-GCK          QGKVLDDPVVTRIAEATGKTPAQVVLRWHIQRGDIVFPKSVTLQRIKDNF
Mvan_1769|M.vanbaalenii_PYR-1       QGKVLDDPVVTRIAETVGKSPAQVVLRWHIQRGDIVFPKSVTLQRIKDNF
MAV_1085|M.avium_104                QGDVLGDAVINRIADGLGRTAAPVVLRWHIQRGDIVFPKTVNPDRMKSNF
TH_1525|M.thermoresistible__bu      KGRVADDPVIAGIADRLGRTPAQVTLRWHIQRGDIVLPKSVTPERVRSNI
MAB_1528c|M.abscessus_ATCC_199      QGTILEDATIGAIAQAHDVSAAQVILRWHLQLGNVVIPKSVTPARIAANF
MSMEG_2408|M.smegmatis_MC2_155      QGSLLADPVITGIAEQHGKTPAQVLIRWHIQLGNIVIPKSVNPERIASNF
Mb2996|M.bovis_AF2122/97            LGRLLDNPTVTSIASEYVKTPAQVLLRWNLQLGNAVVVRSARPERIASNF
Rv2971|M.tuberculosis_H37Rv         LGRLLDNPTVTSIASEYVKTPAQVLLRWNLQLGNAVVVRSARPERIASNF
MLBr_01669|M.leprae_Br4923          LGRLMDNSTLTAIAAEYGKTPAQVLLRWNLQLGNAVVFRSAKAEHIASNF
MMAR_1744|M.marinum_M               LGQLADNPTVTSIAGEYGKTPTQVLLRWNLQLGNAVIFGSSNAEHIATNL
MUL_1987|M.ulcerans_Agy99           LGQLADNPTVTSIAGEYGKTPTQVLLRWNLQLGNAVIFGSSNAEHIVTNL
                                     * :  :..:  **     :.: * :**::* *: *.  :    ::  *:

Mflv_4697|M.gilvum_PYR-GCK          ALFDFELGAEDFDAVSGLDKGEAGRIGPNPDTFDYVPS
Mvan_1769|M.vanbaalenii_PYR-1       ALFDFELGADDFAAISGLDQGEAGRIGPNPDTFDYIP-
MAV_1085|M.avium_104                ELFDFELDERAMEAISALDRGESGRRGPNPDTFDYIPR
TH_1525|M.thermoresistible__bu      ALFDFELSDADMAAISALDKGEAGRMGPHPDKFDMI--
MAB_1528c|M.abscessus_ATCC_199      DVFGFELSTDEVERITALDASD-GRIGPDPTTFNLH--
MSMEG_2408|M.smegmatis_MC2_155      DVFDFELSGQDITSIASLETGK--RLGPDPRTFNFTG-
Mb2996|M.bovis_AF2122/97            DVFDFELAAEHMDALGGLNDGT--RVREDPLTYAGT--
Rv2971|M.tuberculosis_H37Rv         DVFDFELAAEHMDALGGLNDGT--RVREDPLTYAGT--
MLBr_01669|M.leprae_Br4923          DVFDFELAVNHMDAMNELHDGT--RLRPDPETYAGS--
MMAR_1744|M.marinum_M               DVFEFELASQHMDAINGLNDGT--RLREDPMTFAGV--
MUL_1987|M.ulcerans_Agy99           DVFEFELASQHMDAINGLNDGT--RLREDPMTFAGV--
                                     :* ***    .  :  *. .   *   .* .: