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ASPANYDVSALTREDEGYHKGLKNRQVQMIGIGGAIGTGLFMGAGGRLHSAGPGLFVVYAICGLFVFFML RALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMCFVNWASTSIVDVTAVALYMHYWGAFKAVPQWVIA LIALIIVLTMNMISVKLFGEMEFWAALIKVVALVAFLIFGIVFLAGRFTVDGSTTGLSVIADNGGLFPNG LLAMVLITSGVVFAYASVELVGTAAGETENPEKVMPKAINAVVFRIAIFYVGSLVLLALLLPYTTYKAGE SPFVTFFARVGVPHAGDVMNFVVLTAALSSLNAGLYSTGRILRSMSMNGSAPSFLSRMSSGGVPYPGILL TGSFTVLGVFMNMVIPARAFETALDVAALGILASWATIVICQLRLYQWSRHGILKRGKFQMPGAPYTGYA TVVFLIAVLLLMCYENYWNLVAIGIFTPLLIIGWYLQRDRVMRLAQERVGYTGAYPVIAETPMMDDPPNL GDK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1132c | - | - | 100% (494) | L-asparagine ABC transporter permease |
| M. abscessus ATCC 19977 | MAB_2914 | - | 0.0 | 78.94% (489) | L-asparagine permease 1 (L-asparagine transport) |
| M. abscessus ATCC 19977 | MAB_3866c | - | e-101 | 42.34% (444) | putative amino acid permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2151 | ansP1 | 0.0 | 64.48% (473) | L-asparagine permease ansP1 |
| M. gilvum PYR-GCK | Mflv_1998 | - | 2e-68 | 37.23% (376) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv2127 | ansP1 | 0.0 | 64.69% (473) | L-asparagine permease ansP1 |
| M. leprae Br4923 | MLBr_01305 | ansP2 | 0.0 | 63.42% (473) | putative L-asparagine permease |
| M. marinum M | MMAR_4815 | ansP1 | 0.0 | 67.21% (488) | L-asparagine permease AnsP1 |
| M. avium 104 | MAV_4626 | - | 4e-71 | 37.02% (416) | gaba permease |
| M. smegmatis MC2 155 | MSMEG_3587 | - | 1e-79 | 35.21% (463) | D-serine/D-alanine/glycine transporter |
| M. thermoresistible (build 8) | TH_0471 | - | 4e-19 | 23.48% (443) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_0383 | ansP1 | 0.0 | 66.39% (488) | L-asparagine permease AnsP1 |
| M. vanbaalenii PYR-1 | Mvan_3196 | - | 1e-19 | 21.76% (455) | ethanolamine transproter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2151|M.bovis_AF2122/97 ---------MSAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGA----IGT
Rv2127|M.tuberculosis_H37Rv ---------MSAASQRVGAFGEEAGYHKGLKPRQLQMIGIGGA----IGT
MLBr_01305|M.leprae_Br4923 MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIGGA----IGT
MMAR_4815|M.marinum_M ----MRTPSSPTHPDDIALASEDAGYHKSLKPRQLQMIAIGGA----IGT
MUL_0383|M.ulcerans_Agy99 ----MRTPSSPTHPDDIALASEDAGYHKSLKPRQLQMIAIGGA----IGT
MAB_1132c|M.abscessus_ATCC_199 -------MASPANYDVSALTREDEGYHKGLKNRQVQMIGIGGA----IGT
MSMEG_3587|M.smegmatis_MC2_155 --------------MSEQTLPEAEHLSRQLSNRHIQLIAIGGA----IGT
Mflv_1998|M.gilvum_PYR-GCK -------------------MSAAPTLKKALNQRQLTMIAIGGV----IGA
MAV_4626|M.avium_104 -------------------MAGTSQLRQGLSQRQLSMIALGGV----IGA
Mvan_3196|M.vanbaalenii_PYR-1 -MSGEAHSTHTTRGVEAHRESDAYLQKRQLKKGSAGWILLAGLGISYVVS
TH_0471|M.thermoresistible__bu --MTDRLRVKSVEQSIADTDEPDSRLRKDLSWWDLTVFGVSVV----IGA
: *. : :. : :
Mb2151|M.bovis_AF2122/97 GLFLGASGRLAKAGP-GLFLVYGVCGVFVFLILRALGELVLHRPSSGSFV
Rv2127|M.tuberculosis_H37Rv GLFLGAGGRLAKAGP-GLFLVYGVCGVFVFLILRALGELVLHRPSSGSFV
MLBr_01305|M.leprae_Br4923 GLFLGAGGRLAKAGP-GLFLVYAVCGVFVFLILRALGELVLHRPSSGSFV
MMAR_4815|M.marinum_M GLFLGAGGRLASAGP-ALFLVYAVCGVFAFLILRALGELVLHRPSSGSFV
MUL_0383|M.ulcerans_Agy99 GLFLGAGGRLASAGP-ALFLVYAVCGVFAFLILRALSELVLHRPSSGSFV
MAB_1132c|M.abscessus_ATCC_199 GLFMGAGGRLHSAGP-GLFVVYAICGLFVFFMLRALGELVLHRPSSGSFV
MSMEG_3587|M.smegmatis_MC2_155 GLFMGSGKTVSLAGP-SVIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFA
Mflv_1998|M.gilvum_PYR-GCK GLFVGSGVVIADTGP-GAFLTYGMAGVLIIMVMRMLAEMAVANPSTGSFA
MAV_4626|M.avium_104 GLFVGSGVVIKDTGP-AAFLTYALCGLLIVLVMRMLGEMAAANPSTGSFA
Mvan_3196|M.vanbaalenii_PYR-1 GDYSGWNFGLGQGGFGGLAIAAVVIAAMYLAMVLGMAEMSSALPAAGGGY
TH_0471|M.thermoresistible__bu GIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEFASTVPVAGSAY
* : . . : . .*: .
Mb2151|M.bovis_AF2122/97 SYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQW
Rv2127|M.tuberculosis_H37Rv SYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQW
MLBr_01305|M.leprae_Br4923 SYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHRWTIFTALPQW
MMAR_4815|M.marinum_M SYAREFFGEKAAYVAGWMYFLNWAMTSIVDSTAIATYFHFWRVFEGIPQW
MUL_0383|M.ulcerans_Agy99 SYAREFFGEKAAYVAGWMYFLNWAMTSIVDSTAIATYFHFWRVFEGIPQW
MAB_1132c|M.abscessus_ATCC_199 SYAREFLGEKAAYVAGWMCFVNWASTSIVDVTAVALYMHYWGAFKAVPQW
MSMEG_3587|M.smegmatis_MC2_155 DFAADLLGPWAGFFTGWTYWFCWIVTGVAEVVAIAGYVAFW--WPDLPLW
Mflv_1998|M.gilvum_PYR-GCK DYSRNALGHWAGFSVGWLYWYFWVIVVGFEAIAGAKIVQYW---MDVPLW
MAV_4626|M.avium_104 DYAAAALGRWAGFSVAWLYWYFWVIVVGFEAVAGGKVLNYW---FHAPLW
Mvan_3196|M.vanbaalenii_PYR-1 TFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVESLGLFGITDGW
TH_0471|M.thermoresistible__bu TFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLGEVFEFAGATTR
:: :* .: . : . . .
Mb2151|M.bovis_AF2122/97 I-------LALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLVVG
Rv2127|M.tuberculosis_H37Rv I-------LALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLVVG
MLBr_01305|M.leprae_Br4923 T-------LALLALAVVLVMNLISVEWFGELEFWAALIKVCALMAFLVVG
MMAR_4815|M.marinum_M A-------LALFALGIALSMNLISVTLFGEIEFWAALIKVVSLLTFLVVG
MUL_0383|M.ulcerans_Agy99 A-------LALFALGIALSMNLISETLFGEIEFWAALIKVVSLLTFRVVG
MAB_1132c|M.abscessus_ATCC_199 V-------IALIALIIVLTMNMISVKLFGEMEFWAALIKVVALVAFLIFG
MSMEG_3587|M.smegmatis_MC2_155 I-------PALVTVAVLITLNLATVRAFGETEFWFAMIKIVAILALIVVG
Mflv_1998|M.gilvum_PYR-GCK L-------SALIFMVLMTATNLFSVASYGEFEFWFAGIKVAAIIAFIAVG
MAV_4626|M.avium_104 V-------LSLGLMLLMTATNLFSVSSFGEFEFWFAGIKVATIVIFLVVG
Mvan_3196|M.vanbaalenii_PYR-1 W-------VYLAAYAIFIGIHLSGVGEALKVMFVITAIALVGLVVFAVAA
TH_0471|M.thermoresistible__bu LGPITLDWGALLIIGFVTVLLATGTKLSANVSLAITVIKVGVVLLVVIVG
* . : : : * : :: . .
Mb2151|M.bovis_AF2122/97 TVFLAGRYPVDG-------------HSTGLSLWNNHGGLFPTSWLPLLIV
Rv2127|M.tuberculosis_H37Rv TVFLAGRYPVDG-------------HSTGLSLWNNHGGLFPTSWLPLLIV
MLBr_01305|M.leprae_Br4923 TIFLGGRYPVDG-------------HNTGLSLWTSHGGLFPTGVAPLIVV
MMAR_4815|M.marinum_M TIFLAGRYPVDG-------------HSTGLGLLAHGGGLFPYGLLPLVVV
MUL_0383|M.ulcerans_Agy99 TIFLAGRYPVDG-------------HSTGLGLLAHGGGLFPYGLLPLVVV
MAB_1132c|M.abscessus_ATCC_199 IVFLAGRFTVDG-------------STTGLSVIADNGGLFPNGLLAMVLI
MSMEG_3587|M.smegmatis_MC2_155 LVMVLSHFRAPGG------------AVASLSNLWDDGGFFPTGPMGFVAG
Mflv_1998|M.gilvum_PYR-GCK AAFVLGLWPGKG---------------ADFSNLTSHGGFMPLGFGAITVG
MAV_4626|M.avium_104 AAYVIGLVPGHH---------------DGLTNLVSHGGFFPRGVGAVFAA
Mvan_3196|M.vanbaalenii_PYR-1 IPHFDSTNLTDI----------------AVTDAAGASALLPFGLLGIWAA
TH_0471|M.thermoresistible__bu AFFIKAANYTPFIPPAEAGGEAGRSLDQSLFSLITGAEGSSYGWYGLLAG
. . . . . . .
Mb2151|M.bovis_AF2122/97 TSGVVFAYSAVELVGTAAGETAEPEKIMPRAINSVVARIAIFYVGSVALL
Rv2127|M.tuberculosis_H37Rv TSGVVFAYSAVELVGTAAGETAEPEKIMPRAINSVVARIAIFYVGSVALL
MLBr_01305|M.leprae_Br4923 SSGVMFAYAAVELVGTAAGETVEPKKIMPRAINSVIARIAIFYVGSVILL
MMAR_4815|M.marinum_M TSGVVFAYAAVELVGTAAGETAEPEKVMPRAINSVIARIALFYVGSLFLL
MUL_0383|M.ulcerans_Agy99 TSGVVFAYAAVELVGTAAGETAEPEKVMPRAINSVIARIALFYVGSLFLL
MAB_1132c|M.abscessus_ATCC_199 TSGVVFAYASVELVGTAAGETENPEKVMPKAINAVVFRIAIFYVGSLVLL
MSMEG_3587|M.smegmatis_MC2_155 FQIATFAFVGIELVGTTAAEARDPERNLPRAVNSIPVRVMLFYVAALVII
Mflv_1998|M.gilvum_PYR-GCK IVTVIFSMVGAEIATIAAAESQDPERAVAKAANSVILRILIFYVGAVLLL
MAV_4626|M.avium_104 IVVVIFSMVGAEIVTVAAAESRDPRRAVQKATRSVVTRIGIFFVGSVFLL
Mvan_3196|M.vanbaalenii_PYR-1 IPFAIWFFLAIEGVPLAAEETAEPERNVP---KGIIAGMAVLLVTCVTVL
TH_0471|M.thermoresistible__bu ASIVFFAFIGFDIIATTAEETKNPQRDVARGIMATLGIVTVLYVAVSLVL
. : . : :* *: :*.: : . : :: * ::
Mb2151|M.bovis_AF2122/97 ALLLPYTAYKAG--ESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGL
Rv2127|M.tuberculosis_H37Rv ALLLPYTAYKAG--ESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGL
MLBr_01305|M.leprae_Br4923 ALLLPYSAFKAS--ESPFVTFFSKVGFYGAGDLMNIVVLTAALSSLNAGL
MMAR_4815|M.marinum_M GLLLPYTDYKAG--ESPFVTFFDKIGVTGAGSIMNVVVMTAAFSSLNAGL
MUL_0383|M.ulcerans_Agy99 GLLLPYTDYKAG--ESPFVTFFDKIGVTGAGSIMNVVVMTAAFSSLNAGL
MAB_1132c|M.abscessus_ATCC_199 ALLLPYTTYKAG--ESPFVTFFARVGVPHAGDVMNFVVLTAALSSLNAGL
MSMEG_3587|M.smegmatis_MC2_155 IAVTPWREISPD--RSPFVAMFSLAGLGIAASVVNFVVLTSAASSANSGI
Mflv_1998|M.gilvum_PYR-GCK VLIVPWNDESVS--ASPFVAAFNAMGIPYADHVMNAVVLTAVLSCLNSGM
MAV_4626|M.avium_104 VAILPWDSVELG--ASPYVAALKHLGLAGADQVMNAVVLTAVLSCLNSGL
Mvan_3196|M.vanbaalenii_PYR-1 VLTTGAGGAAAM--SESGNPLVEALGDSGWAKVVNYIGLAGLIASFFSII
TH_0471|M.thermoresistible__bu TGMVHYTELRAAGENANLATAFAANGIDWAAKVISIGALAGLTTVVIVLV
. . * ::. ::. : :
Mb2151|M.bovis_AF2122/97 YSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNAFK
Rv2127|M.tuberculosis_H37Rv YSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNAFK
MLBr_01305|M.leprae_Br4923 YATGRVMHSIAINGSGPKFTARMSKNGVPYGGILLAAVICLCGVALNAFN
MMAR_4815|M.marinum_M YSTGRILRSMAMNGSAPSFTARMSQRGVPYGGICLTAAIGLIGVLLNGVV
MUL_0383|M.ulcerans_Agy99 YSTGRILRSMAMNGSAPSFTARMSQRGVPYGGICLTAAIGLIGVLLNGVV
MAB_1132c|M.abscessus_ATCC_199 YSTGRILRSMSMNGSAPSFLSRMSSGGVPYPGILLTGSFTVLGVFMNMVI
MSMEG_3587|M.smegmatis_MC2_155 YSTSRMVYGLSCGGDAPASFGRLTSRRVPANALFLSGVVLLSSVVMVAAG
Mflv_1998|M.gilvum_PYR-GCK YTASRMLFVLAARREAPAALVKVTNRGVPANAILASSVVGFLCVIAAAVS
MAV_4626|M.avium_104 YTASRMLFVLAERGEAPARLVRLSGRGVPHIAILCSSAVGFLCVVMARVA
Mvan_3196|M.vanbaalenii_PYR-1 YAYSRQLFALSRAGYLPTVLSVTNSRKAPTLALIVPGVIGFLLSLIG---
TH_0471|M.thermoresistible__bu LGQTRVLFAMSRDGLLPRPLSKTGPRGTPVRITVLVGALVAIAASVFPVG
* : :: * .* . .
Mb2151|M.bovis_AF2122/97 P--GEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPF
Rv2127|M.tuberculosis_H37Rv P--GEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPF
MLBr_01305|M.leprae_Br4923 P--GQAFEIVLSVAALGIIAGWGTIVLCQLRLHKMAKAGIMRRPRFRMPL
MMAR_4815|M.marinum_M P--EMAFEIVLNIAALGILASWATIVCCQIQLFRWSKQGIVYRPSFRMWG
MUL_0383|M.ulcerans_Agy99 P--EMAFEIVLNIAALGILASWATIVCCQIQLFRWSKQGIVYRPSFRMWG
MAB_1132c|M.abscessus_ATCC_199 P--ARAFETALDVAALGILASWATIVICQLRLYQWSRHGILKRGKFQMPG
MSMEG_3587|M.smegmatis_MC2_155 DSIIAAFTLVTTISSLCFMFIWT-IILSSYLVYRRRRPQQHSASPFKMPG
Mflv_1998|M.gilvum_PYR-GCK P--DTIFAFLLNSSGAIILFVYLLIAISQIVLRYRTPDSKLRVKMWLFPV
MAV_4626|M.avium_104 P--NTVFLFLLNSSGAIILFVYWLIALSQIVLRRRTPAERLSVKMWFFPV
Mvan_3196|M.vanbaalenii_PYR-1 -----QGALLLNMAVFGAALSYVLMMVSHIVLRRREPD---MPRPYRTPG
TH_0471|M.thermoresistible__bu N--------LEEMVNIGTLFAFALVSAGVIVLRRTRPD---LKRGFRVPF
: : : :
Mb2151|M.bovis_AF2122/97 SPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAG-WYLVRK
Rv2127|M.tuberculosis_H37Rv SPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAG-WYLVRK
MLBr_01305|M.leprae_Br4923 APYSGYLTLAFLFAVLVVMAFDKPIGTWTVASLIVIVPALIAG-WYSIRK
MMAR_4815|M.marinum_M APYTGYLTLVFLFAVLVLMGFSYPIGTWTVATLGLIIPMLIGG-WFLVRD
MUL_0383|M.ulcerans_Agy99 APYTGYLTLVFLFAVLVLMGFSYPIDTWTVATLGLIIPMLIGG-WFLVRD
MAB_1132c|M.abscessus_ATCC_199 APYTGYATVVFLIAVLLLMCYEN---YWNLVAIGIFTPLLIIG-WYLQRD
MSMEG_3587|M.smegmatis_MC2_155 GVVMCWVVLAFFVFLVWAFTQKSD---------TLQALLVTPA-WFVVLG
Mflv_1998|M.gilvum_PYR-GCK LSGLTALGILAILVQMFIDTALRSQLVLSLLSWAVVIALFAANKWFVKKR
MAV_4626|M.avium_104 LSVLTLAGITAVLVQMAFDATARSQLWLSLLSWAVVVALY-----FVAR-
Mvan_3196|M.vanbaalenii_PYR-1 GVVTTGFALVIAVLAVIATFLVDS-----VAALCCLVVFAAFMAYFGIYS
TH_0471|M.thermoresistible__bu VPWLPLAAIAACLWLMLNLTGLTWVRFLGWMALGLVLYFFYGRHHSMLGR
: . :
Mb2151|M.bovis_AF2122/97 RVMAVARERLGHTGPFPAVANPPVRSRD----------------------
Rv2127|M.tuberculosis_H37Rv RVMAVARERLGHTGPFPAVANPPVRSRD----------------------
MLBr_01305|M.leprae_Br4923 RVMTIARERMGYTGPFPAIANPPVQPSERSHSQNP---------------
MMAR_4815|M.marinum_M RVLEIARRRIGYTGEFPVVANPGPMDKK----------------------
MUL_0383|M.ulcerans_Agy99 RVLEIARRRIGYIGEFPVVANPGPMDKK----------------------
MAB_1132c|M.abscessus_ATCC_199 RVMRLAQERVGYTGAYPVIAETPMMDDPPNLGDK----------------
MSMEG_3587|M.smegmatis_MC2_155 IAWAFLRRRLGHKAREAAFRAALEAESADSAD------------------
Mflv_1998|M.gilvum_PYR-GCK PAEGDSGAPTGPPHRVLVLANRTVDSDELLAELSRIGADQTAEYLVVVPA
MAV_4626|M.avium_104 -SRGRVAAR-----------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 RHHLVANSPDEEFAALAAAEGELK--------------------------
TH_0471|M.thermoresistible__bu GMTDISARRTG---------------------------------------
Mb2151|M.bovis_AF2122/97 --------------------------------------------------
Rv2127|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01305|M.leprae_Br4923 --------------------------------------------------
MMAR_4815|M.marinum_M --------------------------------------------------
MUL_0383|M.ulcerans_Agy99 --------------------------------------------------
MAB_1132c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3587|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK SAVDTGAAATHGPRDVTEATQEAATARLESTLAALRGKNLTVQGELGDYR
MAV_4626|M.avium_104 --------------------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mb2151|M.bovis_AF2122/97 --------------------------------------------------
Rv2127|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01305|M.leprae_Br4923 --------------------------------------------------
MMAR_4815|M.marinum_M --------------------------------------------------
MUL_0383|M.ulcerans_Agy99 --------------------------------------------------
MAB_1132c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3587|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK PLRALDHAVAEFGPDQIVIATLPPEFSMWHRFDVVDRARAQFTVPVTHVV
MAV_4626|M.avium_104 --------------------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mb2151|M.bovis_AF2122/97 -----------
Rv2127|M.tuberculosis_H37Rv -----------
MLBr_01305|M.leprae_Br4923 -----------
MMAR_4815|M.marinum_M -----------
MUL_0383|M.ulcerans_Agy99 -----------
MAB_1132c|M.abscessus_ATCC_199 -----------
MSMEG_3587|M.smegmatis_MC2_155 -----------
Mflv_1998|M.gilvum_PYR-GCK ATSAVGNQVPR
MAV_4626|M.avium_104 -----------
Mvan_3196|M.vanbaalenii_PYR-1 -----------
TH_0471|M.thermoresistible__bu -----------