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RTPSSPTHPDDIALASEDAGYHKSLKPRQLQMIAIGGAIGTGLFLGAGGRLASAGPALFLVYAVCGVFAF LILRALGELVLHRPSSGSFVSYAREFFGEKAAYVAGWMYFLNWAMTSIVDSTAIATYFHFWRVFEGIPQW ALALFALGIALSMNLISVTLFGEIEFWAALIKVVSLLTFLVVGTIFLAGRYPVDGHSTGLGLLAHGGGLF PYGLLPLVVVTSGVVFAYAAVELVGTAAGETAEPEKVMPRAINSVIARIALFYVGSLFLLGLLLPYTDYK AGESPFVTFFDKIGVTGAGSIMNVVVMTAAFSSLNAGLYSTGRILRSMAMNGSAPSFTARMSQRGVPYGG ICLTAAIGLIGVLLNGVVPEMAFEIVLNIAALGILASWATIVCCQIQLFRWSKQGIVYRPSFRMWGAPYT GYLTLVFLFAVLVLMGFSYPIGTWTVATLGLIIPMLIGGWFLVRDRVLEIARRRIGYTGEFPVVANPGPM DKK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4815 | ansP1 | - | 100% (494) | L-asparagine permease AnsP1 |
| M. marinum M | MMAR_0627 | ansP1_1 | 0.0 | 70.15% (459) | L-asparagine permease AnsP1_1 |
| M. marinum M | MMAR_1093 | cycA | 2e-84 | 38.83% (479) | D-serine/D-alanine/glycine transporter, CycA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2151 | ansP1 | 0.0 | 74.31% (471) | L-asparagine permease ansP1 |
| M. gilvum PYR-GCK | Mflv_1998 | - | 7e-74 | 34.89% (450) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv2127 | ansP1 | 0.0 | 74.52% (471) | L-asparagine permease ansP1 |
| M. leprae Br4923 | MLBr_01305 | ansP2 | 0.0 | 71.19% (486) | putative L-asparagine permease |
| M. abscessus ATCC 19977 | MAB_1132c | - | 0.0 | 67.21% (488) | L-asparagine ABC transporter permease |
| M. avium 104 | MAV_4626 | - | 9e-79 | 39.28% (415) | gaba permease |
| M. smegmatis MC2 155 | MSMEG_6196 | - | 6e-77 | 37.00% (427) | gaba permease |
| M. thermoresistible (build 8) | TH_0471 | - | 2e-21 | 23.52% (489) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_0383 | ansP1 | 0.0 | 98.99% (494) | L-asparagine permease AnsP1 |
| M. vanbaalenii PYR-1 | Mvan_1740 | - | 7e-22 | 24.35% (382) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1998|M.gilvum_PYR-GCK ---------------------MSAAPTLKKALNQ----RQLTMIAIGGVI
MAV_4626|M.avium_104 ---------------------MAGTSQLRQGLSQ----RQLSMIALGGVI
MSMEG_6196|M.smegmatis_MC2_155 --------------MLESRSDLSSSDEPRSGLARSLKTRHMTMIAIGGAI
MMAR_4815|M.marinum_M ----------MRTPSSPTHPDDIALASEDAGYHKSLKPRQLQMIAIGGAI
MUL_0383|M.ulcerans_Agy99 ----------MRTPSSPTHPDDIALASEDAGYHKSLKPRQLQMIAIGGAI
Mb2151|M.bovis_AF2122/97 ---------------MSAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGAI
Rv2127|M.tuberculosis_H37Rv ---------------MSAASQRVGAFGEEAGYHKGLKPRQLQMIGIGGAI
MLBr_01305|M.leprae_Br4923 ------MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIGGAI
MAB_1132c|M.abscessus_ATCC_199 -------------MASPANYDVSALTREDEGYHKGLKNRQVQMIGIGGAI
TH_0471|M.thermoresistible__bu --------MTDRLRVKSVEQSIADTDEPDSRLRKDLSWWDLTVFGVSVVI
Mvan_1740|M.vanbaalenii_PYR-1 MVQEPGAQTVGRRRTKSVEQSIADTDEPSTRLRKELNWWDLTVFGVSVVI
: .: ::.:. .*
Mflv_1998|M.gilvum_PYR-GCK GAGLFVGSG-VVIADTGPGAFLTYGMAGVLIIMVMRMLAEMAVANPSTGS
MAV_4626|M.avium_104 GAGLFVGSG-VVIKDTGPAAFLTYALCGLLIVLVMRMLGEMAAANPSTGS
MSMEG_6196|M.smegmatis_MC2_155 GAGLFVGSG-AVIKTAGPAAIVSYVVAGALVLCTLRMLGEMVVAKPRTGA
MMAR_4815|M.marinum_M GTGLFLGAG-GRLASAGPALFLVYAVCGVFAFLILRALGELVLHRPSSGS
MUL_0383|M.ulcerans_Agy99 GTGLFLGAG-GRLASAGPALFLVYAVCGVFAFLILRALSELVLHRPSSGS
Mb2151|M.bovis_AF2122/97 GTGLFLGAS-GRLAKAGPGLFLVYGVCGVFVFLILRALGELVLHRPSSGS
Rv2127|M.tuberculosis_H37Rv GTGLFLGAG-GRLAKAGPGLFLVYGVCGVFVFLILRALGELVLHRPSSGS
MLBr_01305|M.leprae_Br4923 GTGLFLGAG-GRLAKAGPGLFLVYAVCGVFVFLILRALGELVLHRPSSGS
MAB_1132c|M.abscessus_ATCC_199 GTGLFMGAG-GRLHSAGPGLFVVYAICGLFVFFMLRALGELVLHRPSSGS
TH_0471|M.thermoresistible__bu GAGIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEFASTVPVAGS
Mvan_1740|M.vanbaalenii_PYR-1 GAGIFTITASTAANITGPAISLSFIIAAIACGLAALCYAEFASTVPVAGS
*:*:* :. :**. : : :.. .*:. * :*:
Mflv_1998|M.gilvum_PYR-GCK FADYSRNALGHWAGFSVGWLYWYFWVIVVGFEAIAGAKIVQYW---MDVP
MAV_4626|M.avium_104 FADYAAAALGRWAGFSVAWLYWYFWVIVVGFEAVAGGKVLNYW---FHAP
MSMEG_6196|M.smegmatis_MC2_155 FADYARIGIGPWAGFTLGWLYWYYYVIIIAVEAVAGAQILAVW---VGLP
MMAR_4815|M.marinum_M FVSYAREFFGEKAAYVAGWMYFLNWAMTSIVDSTAIATYFHFWRVFEGIP
MUL_0383|M.ulcerans_Agy99 FVSYAREFFGEKAAYVAGWMYFLNWAMTSIVDSTAIATYFHFWRVFEGIP
Mb2151|M.bovis_AF2122/97 FVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVP
Rv2127|M.tuberculosis_H37Rv FVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVP
MLBr_01305|M.leprae_Br4923 FVSYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHRWTIFTALP
MAB_1132c|M.abscessus_ATCC_199 FVSYAREFLGEKAAYVAGWMCFVNWASTSIVDVTAVALYMHYWGAFKAVP
TH_0471|M.thermoresistible__bu AYTFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLGEVFEFAGAT
Mvan_1740|M.vanbaalenii_PYR-1 AYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFAGGT
:: :* ..: .* : . . . . .
Mflv_1998|M.gilvum_PYR-GCK LWLS-------ALIFMVLMTATNLFSVASYGEFEFWFAGIKVAAIIAFIA
MAV_4626|M.avium_104 LWVL-------SLGLMLLMTATNLFSVSSFGEFEFWFAGIKVATIVIFLV
MSMEG_6196|M.smegmatis_MC2_155 LWLM-------AMLLMAALTLTNLISVRWFGEFEFWFSGIKVAAIVSFIV
MMAR_4815|M.marinum_M QWAL-------ALFALGIALSMNLISVTLFGEIEFWAALIKVVSLLTFLV
MUL_0383|M.ulcerans_Agy99 QWAL-------ALFALGIALSMNLISETLFGEIEFWAALIKVVSLLTFRV
Mb2151|M.bovis_AF2122/97 QWIL-------ALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLV
Rv2127|M.tuberculosis_H37Rv QWIL-------ALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLV
MLBr_01305|M.leprae_Br4923 QWTL-------ALLALAVVLVMNLISVEWFGELEFWAALIKVCALMAFLV
MAB_1132c|M.abscessus_ATCC_199 QWVI-------ALIALIIVLTMNMISVKLFGEMEFWAALIKVVALVAFLI
TH_0471|M.thermoresistible__bu TRLGPITLDWGALLIIGFVTVLLATGTKLSANVSLAITVIKVGVVLLVVI
Mvan_1740|M.vanbaalenii_PYR-1 TEVAGFQLDWGALVIIALVTLILVMGTKLSAGVSLAITAVKVSVVLLVVI
:: : . . ..: : :** :: .
Mflv_1998|M.gilvum_PYR-GCK VGAAFVLG---------LWPGKGAD------FSNLTSHGGFMPLGFGAIT
MAV_4626|M.avium_104 VGAAYVIG---------LVPGHHDG------LTNLVSHGGFFPRGVGAVF
MSMEG_6196|M.smegmatis_MC2_155 VGLLWVFG---------VWPGDTNG------LTNLVAHGGFAPNGFGSIF
MMAR_4815|M.marinum_M VGTIFLAGR-------YPVDGHSTG------LGLLAHGGGLFPYGLLPLV
MUL_0383|M.ulcerans_Agy99 VGTIFLAGR-------YPVDGHSTG------LGLLAHGGGLFPYGLLPLV
Mb2151|M.bovis_AF2122/97 VGTVFLAGR-------YPVDGHSTG------LSLWNNHGGLFPTSWLPLL
Rv2127|M.tuberculosis_H37Rv VGTVFLAGR-------YPVDGHSTG------LSLWNNHGGLFPTSWLPLL
MLBr_01305|M.leprae_Br4923 VGTIFLGGR-------YPVDGHNTG------LSLWTSHGGLFPTGVAPLI
MAB_1132c|M.abscessus_ATCC_199 FGIVFLAGR-------FTVDGSTTG------LSVIADNGGLFPNGLLAMV
TH_0471|M.thermoresistible__bu VGAFFIKAANYTPFIPPAEAGGEAGRSLDQSLFSLITGAEGSSYGWYGLL
Mvan_1740|M.vanbaalenii_PYR-1 VGAFYIKAENFSPFVPAPEEGGSGGTGTEQSLFSLLTGAEGSHYGWYGVL
.* :: . * . : . . :
Mflv_1998|M.gilvum_PYR-GCK VGIVTVIFSMVGAEIATIAAAESQDPERAVAKAANSVILRILIFYVGAVL
MAV_4626|M.avium_104 AAIVVVIFSMVGAEIVTVAAAESRDPRRAVQKATRSVVTRIGIFFVGSVF
MSMEG_6196|M.smegmatis_MC2_155 GAVVVVIFAFGGAEIVTIAAAESAEPAKSVARATTGVIWRIILFYVGSIF
MMAR_4815|M.marinum_M VVTSGVVFAYAAVELVGTAAGETAEPEKVMPRAINSVIARIALFYVGSLF
MUL_0383|M.ulcerans_Agy99 VVTSGVVFAYAAVELVGTAAGETAEPEKVMPRAINSVIARIALFYVGSLF
Mb2151|M.bovis_AF2122/97 IVTSGVVFAYSAVELVGTAAGETAEPEKIMPRAINSVVARIAIFYVGSVA
Rv2127|M.tuberculosis_H37Rv IVTSGVVFAYSAVELVGTAAGETAEPEKIMPRAINSVVARIAIFYVGSVA
MLBr_01305|M.leprae_Br4923 VVSSGVMFAYAAVELVGTAAGETVEPKKIMPRAINSVIARIAIFYVGSVI
MAB_1132c|M.abscessus_ATCC_199 LITSGVVFAYASVELVGTAAGETENPEKVMPKAINAVVFRIAIFYVGSLV
TH_0471|M.thermoresistible__bu AGASIVFFAFIGFDIIATTAEETKNPQRDVARGIMATLGIVTVLYVAVSL
Mvan_1740|M.vanbaalenii_PYR-1 AGASIVFFAFIGFDIVATTAEETRNPQRDVPRGILASLAIVTVLYVAVAV
*.*: . :: :* *: :* : : :. . : : :::*.
Mflv_1998|M.gilvum_PYR-GCK LLVLIVPWNDESVS--ASPFVAAFNAMGIPYADHVMNAVVLTAVLSCLNS
MAV_4626|M.avium_104 LLVAILPWDSVELG--ASPYVAALKHLGLAGADQVMNAVVLTAVLSCLNS
MSMEG_6196|M.smegmatis_MC2_155 LVVCILPWNDASVL--SSPYVAALEKLQIPGAGLIMNIVILTAVLSVLNS
MMAR_4815|M.marinum_M LLGLLLPYTDYKAG--ESPFVTFFDKIGVTGAGSIMNVVVMTAAFSSLNA
MUL_0383|M.ulcerans_Agy99 LLGLLLPYTDYKAG--ESPFVTFFDKIGVTGAGSIMNVVVMTAAFSSLNA
Mb2151|M.bovis_AF2122/97 LLALLLPYTAYKAG--ESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNA
Rv2127|M.tuberculosis_H37Rv LLALLLPYTAYKAG--ESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNA
MLBr_01305|M.leprae_Br4923 LLALLLPYSAFKAS--ESPFVTFFSKVGFYGAGDLMNIVVLTAALSSLNA
MAB_1132c|M.abscessus_ATCC_199 LLALLLPYTTYKAG--ESPFVTFFARVGVPHAGDVMNFVVLTAALSSLNA
TH_0471|M.thermoresistible__bu VLTGMVHYTELRAAGENANLATAFAANGIDWAAKVISIGALAGLTTVVIV
Mvan_1740|M.vanbaalenii_PYR-1 VLTGMVSYTELRDA-ETQNLATAFSLNGVDWAAKVISIGALAGLTTVVIV
:: :: : .: : . * ::. ::. : :
Mflv_1998|M.gilvum_PYR-GCK GMYTASRMLFVLAARREAPAALVKVTNRGVPANAILASSVVGFLCVIAAA
MAV_4626|M.avium_104 GLYTASRMLFVLAERGEAPARLVRLSGRGVPHIAILCSSAVGFLCVVMAR
MSMEG_6196|M.smegmatis_MC2_155 SIYTSSRMLRVLASHGDAPQWLVRTNTRGVPTRAILASTVVGWVSVVLAY
MMAR_4815|M.marinum_M GLYSTGRILRSMAMNGSAPSFTARMSQRGVPYGGICLTAAIGLIGVLLNG
MUL_0383|M.ulcerans_Agy99 GLYSTGRILRSMAMNGSAPSFTARMSQRGVPYGGICLTAAIGLIGVLLNG
Mb2151|M.bovis_AF2122/97 GLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNA
Rv2127|M.tuberculosis_H37Rv GLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNA
MLBr_01305|M.leprae_Br4923 GLYATGRVMHSIAINGSGPKFTARMSKNGVPYGGILLAAVICLCGVALNA
MAB_1132c|M.abscessus_ATCC_199 GLYSTGRILRSMSMNGSAPSFLSRMSSGGVPYPGILLTGSFTVLGVFMNM
TH_0471|M.thermoresistible__bu LVLGQTRVLFAMSRDGLLPRPLSKTGPRGTPVR---ITVLVGALVAIAAS
Mvan_1740|M.vanbaalenii_PYR-1 LVLGQTRVLFAMSRDGLLPRQLAKTGEHGTPVR---ITLIVGAVVAVTAT
: *:: :: * : *.* : . .
Mflv_1998|M.gilvum_PYR-GCK VSPDTIFAFLLNSSGAIILFVYLLIAISQIVLR---YRTPDSKLRVKMWL
MAV_4626|M.avium_104 VAPNTVFLFLLNSSGAIILFVYWLIALSQIVLR---RRTPAERLSVKMWF
MSMEG_6196|M.smegmatis_MC2_155 IAPDSLFLFLVNSCGVVAIFMYVMIGVSELRVRRAIEREDPAKLTLKMWF
MMAR_4815|M.marinum_M VVPEMAFEIVLNIAALGILASWATIVCCQIQLFRWSKQGIVYRPSFRMWG
MUL_0383|M.ulcerans_Agy99 VVPEMAFEIVLNIAALGILASWATIVCCQIQLFRWSKQGIVYRPSFRMWG
Mb2151|M.bovis_AF2122/97 FKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPF
Rv2127|M.tuberculosis_H37Rv FKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPF
MLBr_01305|M.leprae_Br4923 FNPGQAFEIVLSVAALGIIAGWGTIVLCQLRLHKMAKAGIMRRPRFRMPL
MAB_1132c|M.abscessus_ATCC_199 VIPARAFETALDVAALGILASWATIVICQLRLYQWSRHGILKRGKFQMPG
TH_0471|M.thermoresistible__bu VFPVGNLEEMVN---IGTLFAFALVSAGVIVLR---RTRPDLKRGFRVPF
Mvan_1740|M.vanbaalenii_PYR-1 VFPIGKLEEMVN---IGTLFAFVLVSAGVLVLR---RTRPDLKRGFRTPW
. * : :. : : : : : : .:
Mflv_1998|M.gilvum_PYR-GCK FPVLSGLTALGILAILVQMFIDTALRSQLVLSLLSWAVVIALFAANKWFV
MAV_4626|M.avium_104 FPVLSVLTLAGITAVLVQMAFDATARSQLWLSLLSWAVVVALY-----FV
MSMEG_6196|M.smegmatis_MC2_155 FPYLPIAVIACFVLVLVAMLFDADQRVQLLASVVSLAVVLLAYALRKRHG
MMAR_4815|M.marinum_M APYTGYLTLVFLFAVLVLMGFSYPIGTWTVATLGLIIPMLIGGWFLVRDR
MUL_0383|M.ulcerans_Agy99 APYTGYLTLVFLFAVLVLMGFSYPIDTWTVATLGLIIPMLIGGWFLVRDR
Mb2151|M.bovis_AF2122/97 SPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKR
Rv2127|M.tuberculosis_H37Rv SPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKR
MLBr_01305|M.leprae_Br4923 APYSGYLTLAFLFAVLVVMAFDKPIGTWTVASLIVIVPALIAGWYSIRKR
MAB_1132c|M.abscessus_ATCC_199 APYTGYATVVFLIAVLLLMCYEN---YWNLVAIGIFTPLLIIGWYLQRDR
TH_0471|M.thermoresistible__bu VPWLPLAAIAACLWLMLNLTGLTWVRFLGWMALGLVLYFFYGRHHSMLGR
Mvan_1740|M.vanbaalenii_PYR-1 VPLLPILAIAACVWLMLNLTGLTWIRFLIWMAIGVVVYFLYGRRHSLVGR
* . ::: : :: .
Mflv_1998|M.gilvum_PYR-GCK KKRPAEGDSGAPTGPPHRVLVLANRTVDSDELLAELSRIGADQTAEYLVV
MAV_4626|M.avium_104 AR--SRGRVAAR--------------------------------------
MSMEG_6196|M.smegmatis_MC2_155 QVPATDTKQAARTDE-----------------------------------
MMAR_4815|M.marinum_M VLEIARRRIGYTGEFPVVANPGPMDKK-----------------------
MUL_0383|M.ulcerans_Agy99 VLEIARRRIGYIGEFPVVANPGPMDKK-----------------------
Mb2151|M.bovis_AF2122/97 VMAVARERLGHTGPFPAVANPPVRSRD-----------------------
Rv2127|M.tuberculosis_H37Rv VMAVARERLGHTGPFPAVANPPVRSRD-----------------------
MLBr_01305|M.leprae_Br4923 VMTIARERMGYTGPFPAIANPPVQPSERSHSQNP----------------
MAB_1132c|M.abscessus_ATCC_199 VMRLAQERVGYTGAYPVIAETPMMDDPPNLGDK-----------------
TH_0471|M.thermoresistible__bu GMTDISARRTG---------------------------------------
Mvan_1740|M.vanbaalenii_PYR-1 RMG-----------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK VPASAVDTGAAATHGPRDVTEATQEAATARLESTLAALRGKNLTVQGELG
MAV_4626|M.avium_104 --------------------------------------------------
MSMEG_6196|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4815|M.marinum_M --------------------------------------------------
MUL_0383|M.ulcerans_Agy99 --------------------------------------------------
Mb2151|M.bovis_AF2122/97 --------------------------------------------------
Rv2127|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01305|M.leprae_Br4923 --------------------------------------------------
MAB_1132c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mvan_1740|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK DYRPLRALDHAVAEFGPDQIVIATLPPEFSMWHRFDVVDRARAQFTVPVT
MAV_4626|M.avium_104 --------------------------------------------------
MSMEG_6196|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4815|M.marinum_M --------------------------------------------------
MUL_0383|M.ulcerans_Agy99 --------------------------------------------------
Mb2151|M.bovis_AF2122/97 --------------------------------------------------
Rv2127|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01305|M.leprae_Br4923 --------------------------------------------------
MAB_1132c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mvan_1740|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK HVVATSAVGNQVPR
MAV_4626|M.avium_104 --------------
MSMEG_6196|M.smegmatis_MC2_155 --------------
MMAR_4815|M.marinum_M --------------
MUL_0383|M.ulcerans_Agy99 --------------
Mb2151|M.bovis_AF2122/97 --------------
Rv2127|M.tuberculosis_H37Rv --------------
MLBr_01305|M.leprae_Br4923 --------------
MAB_1132c|M.abscessus_ATCC_199 --------------
TH_0471|M.thermoresistible__bu --------------
Mvan_1740|M.vanbaalenii_PYR-1 --------------