For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LSAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGASGRLAKAGPGLFLVYGVCGVFVFLILR ALGELVLHRPSSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQWILAL IALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLVVGTVFLAGRYPVDGHSTGLSLWNNHGGLFPTSW LPLLIVTSGVVFAYSAVELVGTAAGETAEPEKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGES PFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLT AVITLFGVALNAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPFSPYSGYLT LLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAVANPPVRSRD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2151 | ansP1 | - | 100% (489) | L-asparagine permease ansP1 |
| M. bovis AF2122 / 97 | Mb0354c | ansP2 | 0.0 | 72.94% (462) | L-asparagine ABC transporter permease |
| M. bovis AF2122 / 97 | Mb1730c | cycA | 1e-85 | 38.41% (453) | D-serine/alanine/glycine transporter protein CycA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1998 | - | 2e-76 | 36.47% (447) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv2127 | ansP1 | 0.0 | 99.59% (489) | L-asparagine permease ansP1 |
| M. leprae Br4923 | MLBr_01305 | ansP2 | 0.0 | 82.85% (484) | putative L-asparagine permease |
| M. abscessus ATCC 19977 | MAB_2914 | - | 0.0 | 65.96% (473) | L-asparagine permease 1 (L-asparagine transport) |
| M. marinum M | MMAR_4815 | ansP1 | 0.0 | 74.31% (471) | L-asparagine permease AnsP1 |
| M. avium 104 | MAV_4626 | - | 3e-75 | 36.73% (452) | gaba permease |
| M. smegmatis MC2 155 | MSMEG_3587 | - | 7e-75 | 34.64% (459) | D-serine/D-alanine/glycine transporter |
| M. thermoresistible (build 8) | TH_0471 | - | 2e-18 | 23.25% (456) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_0383 | ansP1 | 0.0 | 73.25% (471) | L-asparagine permease AnsP1 |
| M. vanbaalenii PYR-1 | Mvan_1740 | - | 2e-19 | 23.92% (372) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2151|M.bovis_AF2122/97 ---------------MSAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGAI
Rv2127|M.tuberculosis_H37Rv ---------------MSAASQRVGAFGEEAGYHKGLKPRQLQMIGIGGAI
MLBr_01305|M.leprae_Br4923 ------MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIGGAI
MMAR_4815|M.marinum_M ----------MRTPSSPTHPDDIALASEDAGYHKSLKPRQLQMIAIGGAI
MUL_0383|M.ulcerans_Agy99 ----------MRTPSSPTHPDDIALASEDAGYHKSLKPRQLQMIAIGGAI
MAB_2914|M.abscessus_ATCC_1997 -------------MTSPATYDTSAPAPEEQGYHKGLNNRQVQMIGIGGAI
MSMEG_3587|M.smegmatis_MC2_155 --------------------MSEQTLPEAEHLSRQLSNRHIQLIAIGGAI
Mflv_1998|M.gilvum_PYR-GCK -------------------------MSAAPTLKKALNQRQLTMIAIGGVI
MAV_4626|M.avium_104 -------------------------MAGTSQLRQGLSQRQLSMIALGGVI
TH_0471|M.thermoresistible__bu --------MTDRLRVKSVEQSIADTDEPDSRLRKDLSWWDLTVFGVSVVI
Mvan_1740|M.vanbaalenii_PYR-1 MVQEPGAQTVGRRRTKSVEQSIADTDEPSTRLRKELNWWDLTVFGVSVVI
: *. .: ::.:. .*
Mb2151|M.bovis_AF2122/97 GTGLFLGASGRLA-KAGPGLFLVYGVCGVFVFLILRALGELVLHRPSSGS
Rv2127|M.tuberculosis_H37Rv GTGLFLGAGGRLA-KAGPGLFLVYGVCGVFVFLILRALGELVLHRPSSGS
MLBr_01305|M.leprae_Br4923 GTGLFLGAGGRLA-KAGPGLFLVYAVCGVFVFLILRALGELVLHRPSSGS
MMAR_4815|M.marinum_M GTGLFLGAGGRLA-SAGPALFLVYAVCGVFAFLILRALGELVLHRPSSGS
MUL_0383|M.ulcerans_Agy99 GTGLFLGAGGRLA-SAGPALFLVYAVCGVFAFLILRALSELVLHRPSSGS
MAB_2914|M.abscessus_ATCC_1997 GTGLFMGAGGRLH-SAGPGLFLVYAVCGVFVFFILRALGELILHRPSSGS
MSMEG_3587|M.smegmatis_MC2_155 GTGLFMGSGKTVS-LAGPSVIFVYMIIGFMLFFVMRAMGELLLSNLEYKS
Mflv_1998|M.gilvum_PYR-GCK GAGLFVGSGVVIA-DTGPGAFLTYGMAGVLIIMVMRMLAEMAVANPSTGS
MAV_4626|M.avium_104 GAGLFVGSGVVIK-DTGPAAFLTYALCGLLIVLVMRMLGEMAAANPSTGS
TH_0471|M.thermoresistible__bu GAGIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEFASTVPVAGS
Mvan_1740|M.vanbaalenii_PYR-1 GAGIFTITASTAANITGPAISLSFIIAAIACGLAALCYAEFASTVPVAGS
*:*:* :. :**. . : : .. : .*: *
Mb2151|M.bovis_AF2122/97 FVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVP
Rv2127|M.tuberculosis_H37Rv FVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVP
MLBr_01305|M.leprae_Br4923 FVSYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHRWTIFTALP
MMAR_4815|M.marinum_M FVSYAREFFGEKAAYVAGWMYFLNWAMTSIVDSTAIATYFHFWRVFEGIP
MUL_0383|M.ulcerans_Agy99 FVSYAREFFGEKAAYVAGWMYFLNWAMTSIVDSTAIATYFHFWRVFEGIP
MAB_2914|M.abscessus_ATCC_1997 FVSYAREFLGEKAAYVAGWMYFFNWAATAIVDVTAIALYMHYWSAFKAIP
MSMEG_3587|M.smegmatis_MC2_155 FADFAADLLGPWAGFFTGWTYWFCWIVTGVAEVVAIAGYVAFW--WPDLP
Mflv_1998|M.gilvum_PYR-GCK FADYSRNALGHWAGFSVGWLYWYFWVIVVGFEAIAGAKIVQYW---MDVP
MAV_4626|M.avium_104 FADYAAAALGRWAGFSVAWLYWYFWVIVVGFEAVAGGKVLNYW---FHAP
TH_0471|M.thermoresistible__bu AYTFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLGEVFEFAGAT
Mvan_1740|M.vanbaalenii_PYR-1 AYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFAGGT
:: :* ..: .* : . . . . .
Mb2151|M.bovis_AF2122/97 QWIL-------ALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLV
Rv2127|M.tuberculosis_H37Rv QWIL-------ALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLV
MLBr_01305|M.leprae_Br4923 QWTL-------ALLALAVVLVMNLISVEWFGELEFWAALIKVCALMAFLV
MMAR_4815|M.marinum_M QWAL-------ALFALGIALSMNLISVTLFGEIEFWAALIKVVSLLTFLV
MUL_0383|M.ulcerans_Agy99 QWAL-------ALFALGIALSMNLISETLFGEIEFWAALIKVVSLLTFRV
MAB_2914|M.abscessus_ATCC_1997 QWSI-------ALIALVIVLTMNTISVKLFGEMEFWAALIKVVAIMGFLV
MSMEG_3587|M.smegmatis_MC2_155 LWIP-------ALVTVAVLITLNLATVRAFGETEFWFAMIKIVAILALIV
Mflv_1998|M.gilvum_PYR-GCK LWLS-------ALIFMVLMTATNLFSVASYGEFEFWFAGIKVAAIIAFIA
MAV_4626|M.avium_104 LWVL-------SLGLMLLMTATNLFSVSSFGEFEFWFAGIKVATIVIFLV
TH_0471|M.thermoresistible__bu TRLGPITLDWGALLIIGFVTVLLATGTKLSANVSLAITVIKVGVVLLVVI
Mvan_1740|M.vanbaalenii_PYR-1 TEVAGFQLDWGALVIIALVTLILVMGTKLSAGVSLAITAVKVSVVLLVVI
:* : . . .: : :*: :: .
Mb2151|M.bovis_AF2122/97 VGTVFLAGR-------YPVDG------HSTGLSLWNNHGGLFPTSWLPLL
Rv2127|M.tuberculosis_H37Rv VGTVFLAGR-------YPVDG------HSTGLSLWNNHGGLFPTSWLPLL
MLBr_01305|M.leprae_Br4923 VGTIFLGGR-------YPVDG------HNTGLSLWTSHGGLFPTGVAPLI
MMAR_4815|M.marinum_M VGTIFLAGR-------YPVDG------HSTGLGLLAHGGGLFPYGLLPLV
MUL_0383|M.ulcerans_Agy99 VGTIFLAGR-------YPVDG------HSTGLGLLAHGGGLFPYGLLPLV
MAB_2914|M.abscessus_ATCC_1997 IGTVFLAGR-------FTVEG------ASTGPSVIADNGGLLPTGLMALV
MSMEG_3587|M.smegmatis_MC2_155 VGLVMVLSH-------FRAPGG-----AVASLSNLWDDGGFFPTGPMGFV
Mflv_1998|M.gilvum_PYR-GCK VGAAFVLGL-------WPGKG--------ADFSNLTSHGGFMPLGFGAIT
MAV_4626|M.avium_104 VGAAYVIGL-------VPGHH--------DGLTNLVSHGGFFPRGVGAVF
TH_0471|M.thermoresistible__bu VGAFFIKAANYTPFIPPAEAGGEAGRSLDQSLFSLITGAEGSSYGWYGLL
Mvan_1740|M.vanbaalenii_PYR-1 VGAFYIKAENFSPFVPAPEEGGSGGTGTEQSLFSLLTGAEGSHYGWYGVL
:* : . . . . .
Mb2151|M.bovis_AF2122/97 IVTSGVVFAYSAVELVGTAAGETAEPEKIMPRAINSVVARIAIFYVGSVA
Rv2127|M.tuberculosis_H37Rv IVTSGVVFAYSAVELVGTAAGETAEPEKIMPRAINSVVARIAIFYVGSVA
MLBr_01305|M.leprae_Br4923 VVSSGVMFAYAAVELVGTAAGETVEPKKIMPRAINSVIARIAIFYVGSVI
MMAR_4815|M.marinum_M VVTSGVVFAYAAVELVGTAAGETAEPEKVMPRAINSVIARIALFYVGSLF
MUL_0383|M.ulcerans_Agy99 VVTSGVVFAYAAVELVGTAAGETAEPEKVMPRAINSVIARIALFYVGSLF
MAB_2914|M.abscessus_ATCC_1997 IVTSGVVFAYSAVELVGIAAGETENPDKVMPRAINSVVFRVAVFYVGSLI
MSMEG_3587|M.smegmatis_MC2_155 AGFQIATFAFVGIELVGTTAAEARDPERNLPRAVNSIPVRVMLFYVAALV
Mflv_1998|M.gilvum_PYR-GCK VGIVTVIFSMVGAEIATIAAAESQDPERAVAKAANSVILRILIFYVGAVL
MAV_4626|M.avium_104 AAIVVVIFSMVGAEIVTVAAAESRDPRRAVQKATRSVVTRIGIFFVGSVF
TH_0471|M.thermoresistible__bu AGASIVFFAFIGFDIIATTAEETKNPQRDVARGIMATLGIVTVLYVAVSL
Mvan_1740|M.vanbaalenii_PYR-1 AGASIVFFAFIGFDIVATTAEETRNPQRDVPRGILASLAIVTVLYVAVAV
. *: . :: :* *: :* : : :. : : :::*.
Mb2151|M.bovis_AF2122/97 LLALLLPYTAYKAG--ESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNA
Rv2127|M.tuberculosis_H37Rv LLALLLPYTAYKAG--ESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNA
MLBr_01305|M.leprae_Br4923 LLALLLPYSAFKAS--ESPFVTFFSKVGFYGAGDLMNIVVLTAALSSLNA
MMAR_4815|M.marinum_M LLGLLLPYTDYKAG--ESPFVTFFDKIGVTGAGSIMNVVVMTAAFSSLNA
MUL_0383|M.ulcerans_Agy99 LLGLLLPYTDYKAG--ESPFVTFFDKIGVTGAGSIMNVVVMTAAFSSLNA
MAB_2914|M.abscessus_ATCC_1997 LLALLLPYGTYKAG--ESPFVTFFSRIGVPYAGDVMNFVVLTAALSSLNA
MSMEG_3587|M.smegmatis_MC2_155 IIIAVTPWREISPD--RSPFVAMFSLAGLGIAASVVNFVVLTSAASSANS
Mflv_1998|M.gilvum_PYR-GCK LLVLIVPWNDESVS--ASPFVAAFNAMGIPYADHVMNAVVLTAVLSCLNS
MAV_4626|M.avium_104 LLVAILPWDSVELG--ASPYVAALKHLGLAGADQVMNAVVLTAVLSCLNS
TH_0471|M.thermoresistible__bu VLTGMVHYTELRAAGENANLATAFAANGIDWAAKVISIGALAGLTTVVIV
Mvan_1740|M.vanbaalenii_PYR-1 VLTGMVSYTELRDA-ETQNLATAFSLNGVDWAAKVISIGALAGLTTVVIV
:: : : .: : *. * ::. .::. :
Mb2151|M.bovis_AF2122/97 GLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNA
Rv2127|M.tuberculosis_H37Rv GLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNA
MLBr_01305|M.leprae_Br4923 GLYATGRVMHSIAINGSGPKFTARMSKNGVPYGGILLAAVICLCGVALNA
MMAR_4815|M.marinum_M GLYSTGRILRSMAMNGSAPSFTARMSQRGVPYGGICLTAAIGLIGVLLNG
MUL_0383|M.ulcerans_Agy99 GLYSTGRILRSMAMNGSAPSFTARMSQRGVPYGGICLTAAIGLIGVLLNG
MAB_2914|M.abscessus_ATCC_1997 GLYSTGRILRSLAMNGSAPKVLSRMTSGGVPFMGIAVTGALTLVGIFMNL
MSMEG_3587|M.smegmatis_MC2_155 GIYSTSRMVYGLSCGGDAPASFGRLTSRRVPANALFLSGVVLLSSVVMVA
Mflv_1998|M.gilvum_PYR-GCK GMYTASRMLFVLAARREAPAALVKVTNRGVPANAILASSVVGFLCVIAAA
MAV_4626|M.avium_104 GLYTASRMLFVLAERGEAPARLVRLSGRGVPHIAILCSSAVGFLCVVMAR
TH_0471|M.thermoresistible__bu LVLGQTRVLFAMSRDGLLPRPLSKTGPRGTPVRITVLVGALVAIAASVFP
Mvan_1740|M.vanbaalenii_PYR-1 LVLGQTRVLFAMSRDGLLPRQLAKTGEHGTPVRITLIVGAVVAVTATVFP
: *:: :: * : .* ..:
Mb2151|M.bovis_AF2122/97 FKP--GEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRM
Rv2127|M.tuberculosis_H37Rv FKP--GEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRM
MLBr_01305|M.leprae_Br4923 FNP--GQAFEIVLSVAALGIIAGWGTIVLCQLRLHKMAKAGIMRRPRFRM
MMAR_4815|M.marinum_M VVP--EMAFEIVLNIAALGILASWATIVCCQIQLFRWSKQGIVYRPSFRM
MUL_0383|M.ulcerans_Agy99 VVP--EMAFEIVLNIAALGILASWATIVCCQIQLFRWSKQGIVYRPSFRM
MAB_2914|M.abscessus_ATCC_1997 VIP--AEAFETALDLAALGIISSWATIVICQIQLYRWSQRGILQRGSFRM
MSMEG_3587|M.smegmatis_MC2_155 AGDSIIAAFTLVTTISSLCFMFIWT-IILSSYLVYRRRRPQQHSASPFKM
Mflv_1998|M.gilvum_PYR-GCK VSP--DTIFAFLLNSSGAIILFVYLLIAISQIVLRYRTPDSKLRVKMWLF
MAV_4626|M.avium_104 VAP--NTVFLFLLNSSGAIILFVYWLIALSQIVLRRRTPAERLSVKMWFF
TH_0471|M.thermoresistible__bu VGN--------LEEMVNIGTLFAFALVSAGVIVLRRTRPDLKRG---FRV
Mvan_1740|M.vanbaalenii_PYR-1 IGK--------LEEMVNIGTLFAFVLVSAGVLVLRRTRPDLKRG---FRT
: : : : :
Mb2151|M.bovis_AF2122/97 PFSPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAG-WYLV
Rv2127|M.tuberculosis_H37Rv PFSPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAG-WYLV
MLBr_01305|M.leprae_Br4923 PLAPYSGYLTLAFLFAVLVVMAFDKPIGTWTVASLIVIVPALIAG-WYSI
MMAR_4815|M.marinum_M WGAPYTGYLTLVFLFAVLVLMGFSYPIGTWTVATLGLIIPMLIGG-WFLV
MUL_0383|M.ulcerans_Agy99 WGAPYTGYLTLVFLFAVLVLMGFSYPIDTWTVATLGLIIPMLIGG-WFLV
MAB_2914|M.abscessus_ATCC_1997 PGAPYTGYLTLAFLAAVVVLMCYEN---AWNLIAIAVLVPVLTAG-WYLC
MSMEG_3587|M.smegmatis_MC2_155 PGGVVMCWVVLAFFVFLVWAFTQKSD---------TLQALLVTPA-WFVV
Mflv_1998|M.gilvum_PYR-GCK PVLSGLTALGILAILVQMFIDTALRSQLVLSLLSWAVVIALFAANKWFVK
MAV_4626|M.avium_104 PVLSVLTLAGITAVLVQMAFDATARSQLWLSLLSWAVVVALY-----FVA
TH_0471|M.thermoresistible__bu PFVPWLPLAAIAACLWLMLNLTGLTWVRFLGWMALGLVLYFFYGRHHSML
Mvan_1740|M.vanbaalenii_PYR-1 PWVPLLPILAIAACVWLMLNLTGLTWIRFLIWMAIGVVVYFLYGRRHSLV
: : :
Mb2151|M.bovis_AF2122/97 RKRVMAVARERLGHTGPFPAVANPPVRSRD--------------------
Rv2127|M.tuberculosis_H37Rv RKRVMAVARERLGHTGPFPAVANPPVRSRD--------------------
MLBr_01305|M.leprae_Br4923 RKRVMTIARERMGYTGPFPAIANPPVQPSERSHSQNP-------------
MMAR_4815|M.marinum_M RDRVLEIARRRIGYTGEFPVVANPGPMDKK--------------------
MUL_0383|M.ulcerans_Agy99 RDRVLEIARRRIGYIGEFPVVANPGPMDKK--------------------
MAB_2914|M.abscessus_ATCC_1997 RGRVLQLARERIGYTGAYPVIAHTPMLDDPPGESHR--------------
MSMEG_3587|M.smegmatis_MC2_155 LGIAWAFLRRRLGHKAREAAFRAALEAESADSAD----------------
Mflv_1998|M.gilvum_PYR-GCK KRPAEGDSGAPTGPPHRVLVLANRTVDSDELLAELSRIGADQTAEYLVVV
MAV_4626|M.avium_104 R--SRGRVAAR---------------------------------------
TH_0471|M.thermoresistible__bu GRGMTDISARRTG-------------------------------------
Mvan_1740|M.vanbaalenii_PYR-1 GRRMG---------------------------------------------
Mb2151|M.bovis_AF2122/97 --------------------------------------------------
Rv2127|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01305|M.leprae_Br4923 --------------------------------------------------
MMAR_4815|M.marinum_M --------------------------------------------------
MUL_0383|M.ulcerans_Agy99 --------------------------------------------------
MAB_2914|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3587|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK PASAVDTGAAATHGPRDVTEATQEAATARLESTLAALRGKNLTVQGELGD
MAV_4626|M.avium_104 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mvan_1740|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2151|M.bovis_AF2122/97 --------------------------------------------------
Rv2127|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01305|M.leprae_Br4923 --------------------------------------------------
MMAR_4815|M.marinum_M --------------------------------------------------
MUL_0383|M.ulcerans_Agy99 --------------------------------------------------
MAB_2914|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3587|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK YRPLRALDHAVAEFGPDQIVIATLPPEFSMWHRFDVVDRARAQFTVPVTH
MAV_4626|M.avium_104 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mvan_1740|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2151|M.bovis_AF2122/97 -------------
Rv2127|M.tuberculosis_H37Rv -------------
MLBr_01305|M.leprae_Br4923 -------------
MMAR_4815|M.marinum_M -------------
MUL_0383|M.ulcerans_Agy99 -------------
MAB_2914|M.abscessus_ATCC_1997 -------------
MSMEG_3587|M.smegmatis_MC2_155 -------------
Mflv_1998|M.gilvum_PYR-GCK VVATSAVGNQVPR
MAV_4626|M.avium_104 -------------
TH_0471|M.thermoresistible__bu -------------
Mvan_1740|M.vanbaalenii_PYR-1 -------------