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TESDDTQRPVSVAELLARNGAAEGKISGHRRRMRGNADAIPVAELTGEIPVIRDKKGGRARPNPSPAAET AAPEATKAPEAAAPSETRSYLRSNEDALFGGDSMADEAARRGPSTPSTPAQPSSMASSLRSIFPPTPTPA TRPGEPRKSIDFNDATGVISPVTSAPTSEPTPKPTPKPEAAKPVTPVPPAAPSAPPATPPAPVSRPVEPE PEPEPEPEPEAVVQPEAEPEPDARPEVIADEYEDDAECEEDDGEYGRSTAVEWNSHDAEHDVEGAENDYD ENDYQLEHELQELVNEHGSPVDTEASQLADVETEKKTDAEAKAERKEKIKTYLQGGWIAAQYLLAAAAGA GLFFGFRELWSWNQGIALVLGVLFIAILVASLWVIRKTVDLISILIAIVVGALIAFGPLVLMLQAVD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4012c | - | - | 100% (418) | hypothetical protein MAB_4012c |
M. abscessus ATCC 19977 | MAB_3131c | - | 3e-12 | 27.96% (211) | translation initiation factor IF-2 (InfB) |
M. abscessus ATCC 19977 | MAB_0309 | - | 6e-11 | 30.00% (210) | DNA polymerase III, subunit gamma/tau |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0508 | - | 7e-30 | 29.54% (413) | transmembrane protein |
M. gilvum PYR-GCK | Mflv_0078 | - | 1e-37 | 28.83% (437) | hypothetical protein Mflv_0078 |
M. tuberculosis H37Rv | Rv0497 | - | 7e-30 | 29.54% (413) | transmembrane protein |
M. leprae Br4923 | MLBr_02433 | - | 9e-21 | 28.42% (292) | hypothetical protein MLBr_02433 |
M. marinum M | MMAR_0823 | - | 9e-34 | 29.66% (435) | transmembrane protein |
M. avium 104 | MAV_4655 | - | 3e-34 | 31.49% (416) | hypothetical protein MAV_4655 |
M. smegmatis MC2 155 | MSMEG_0940 | - | 8e-35 | 30.17% (421) | hypothetical protein MSMEG_0940 |
M. thermoresistible (build 8) | TH_0882 | - | 2e-31 | 29.51% (427) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
M. ulcerans Agy99 | MUL_4567 | - | 6e-34 | 29.66% (435) | transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_0834 | - | 2e-34 | 31.63% (430) | hypothetical protein Mvan_0834 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0078|M.gilvum_PYR-GCK MTG--TEDSNSSTRPISVAELLAKNGTIGAPPVGGRRRRRRGNSDAVTVA Mvan_0834|M.vanbaalenii_PYR-1 MTG--SDDS-YSTRPISVAELLAKNGTIGSPPVGGRRRRRRGNADAVTVA MSMEG_0940|M.smegmatis_MC2_155 MTG--PEDSQTPSRPISVAELLAKNGTIGAPPVGGRRRRRRGNADAVTVA TH_0882|M.thermoresistible__bu MTE--PEDS---NRPISVAELLARNGTIGAPPVGGRRRRRRGNADAITVA Mb0508|M.bovis_AF2122/97 MTGPHPETESSGNRQISVAELLARQGVTGAP--ARRRRRRRGDSDAITVA Rv0497|M.tuberculosis_H37Rv MTGPHPETESSGNRQISVAELLARQGVTGAP--ARRRRRRRGDSDAITVA MMAR_0823|M.marinum_M MTGPHSETEDT--KQISVAELLARNGNVGAPAVTRRRRRRRGDTDSITVA MUL_4567|M.ulcerans_Agy99 MTGPHSETEDT--KQISVAELLARNGNVGAPAVTRRRRRRRGDTDSITVA MLBr_02433|M.leprae_Br4923 MTGPHNDTESPHARPISVAELLARNGTIGAPAVSRRRRRR-TDSDAVTVA MAV_4655|M.avium_104 MTGPHSETESPGTRPISVAELLARNGTIGAPAVTRRRRRRRGDSDAVTVA MAB_4012c|M.abscessus_ATCC_199 -----MTESDDTQRPVSVAELLARNG-AAEGKISGHRRRMRGNADAIPVA . : :*******::* . :*** ::*::.** Mflv_0078|M.gilvum_PYR-GCK ELTGEIPIIRPDDPPPAPVTAPETVAEPIEEAPAEAEVEVEAEAEVEAES Mvan_0834|M.vanbaalenii_PYR-1 ELTGEIPIVRPDEP------------TPVEEQPGEPEPEPEQATPTNGAV MSMEG_0940|M.smegmatis_MC2_155 ELTGEIPVITDDDS-----------APQTSRRQRERDTSLEETTVVEAVP TH_0882|M.thermoresistible__bu ELTGEIPVVGDDTE------------PEDAQKDGSGPDGSGRAAPVETPA Mb0508|M.bovis_AF2122/97 ELTGEIPIIRDDHH---------------HAGPDAHAS---------QSP Rv0497|M.tuberculosis_H37Rv ELTGEIPIIRDDHH---------------HAGPDAHAS---------QSP MMAR_0823|M.marinum_M ELTGEIPIIRDDHHD-------------ERSAPSAPAETTETVAPTSQAK MUL_4567|M.ulcerans_Agy99 ELTGEIPIIRDDHHD-------------ERSAPSAPAETTETVAPTSQAK MLBr_02433|M.leprae_Br4923 ELTCDIPIIHDDHA---------------DEQHLAATH----------AH MAV_4655|M.avium_104 ELTGEIPVIRDDEP---------------DDQPGATDT----------VD MAB_4012c|M.abscessus_ATCC_199 ELTGEIPVIRDKKGG--------RARPNPSPAAETAAPEATKAPEAAAPS *** :**:: . Mflv_0078|M.gilvum_PYR-GCK EVEAEVEADTAADVEAEDTDVEDATDVEVEATDDVEAPDVEAEAPADVVD Mvan_0834|M.vanbaalenii_PYR-1 DEAASVEPDGELVEPAEDTVTAEDENGETEP--EAES-AIEAEP-----E MSMEG_0940|M.smegmatis_MC2_155 ---AREEAPQAAPEKTPETEPRPARNGATPR----EAAVVADQP-----A TH_0882|M.thermoresistible__bu ERTDEQELPG--PTGRTDLPKRETPTPAPDRDRTGQDRSAHRAP-----R Mb0508|M.bovis_AF2122/97 AANGRVQVGEAAPQSPAEP---VAEQVAEEPT-----------------R Rv0497|M.tuberculosis_H37Rv AANGRVQVGEAAPQSPAEP---VAEQVAEEPT-----------------R MMAR_0823|M.marinum_M PGNGRVEVDEPAPASRVQPESVVAPAEATEPPQAAEEPAAGQAG-----R MUL_4567|M.ulcerans_Agy99 PGNGRVEVDEPAPASRVQPESVVAPAEATEPPQAAEEPAAGQAG-----R MLBr_02433|M.leprae_Br4923 RANIGVRVVEPAAQSPLEP---VCEGIVAEPPVDDH-----GHV-----P MAV_4655|M.avium_104 TA------------APAQP---VAE--PAEPVAEDE-----PKT-----P MAB_4012c|M.abscessus_ATCC_199 ETRSYLRSNEDALFGGDSMADEAARRGPSTPSTPAQPSSMASSLRSIFPP . Mflv_0078|M.gilvum_PYR-GCK TDVQAEATDVDVEAETVEQVA---------PVAPPAAEPSRSRRFGFLR- Mvan_0834|M.vanbaalenii_PYR-1 LEDDEYAKAVAEYAAHMEQRG---------TEPEETAEPAR--RFGFGR- MSMEG_0940|M.smegmatis_MC2_155 PDAGAARDAEADYDAHLKTRE---------IDPEPVEFRPRPRRNQFAS- TH_0882|M.thermoresistible__bu RPAVADSDPDEMVPDPLDDGE---------DAFESPVDLADAPEIDYGP- Mb0508|M.bovis_AF2122/97 TVYWSQPEPRWPKSPPQDRRE---------SGPELSEYPRPLRHTHS--- Rv0497|M.tuberculosis_H37Rv TVYWSQPEPRWPKSPPQDRRE---------SGPELSEYPRPLRHTHS--- MMAR_0823|M.marinum_M AAYWSEPEPRWPKSEPITRTK---------AGPERSEYPRPLRHTG---- MUL_4567|M.ulcerans_Agy99 AAYWSEPEPRWPKSEPITRTK---------AGPERSEYPRPLRHTG---- MLBr_02433|M.leprae_Br4923 PGCWSAPEPRWPKSPPLTHLR---------TGLQRSACSRPLPHLGDVRH MAV_4655|M.avium_104 --YWSEPEPRWPKSPPQPKRA---------PGPERSAYPRPLPEPG---- MAB_4012c|M.abscessus_ATCC_199 TPTPATRPGEPRKSIDFNDATGVISPVTSAPTSEPTPKPTPKPEAAKPVT . Mflv_0078|M.gilvum_PYR-GCK --LGRRSAPAAVTPVAETSVAEVPADQVDTVDDAPVAEETAEIEKTESGE Mvan_0834|M.vanbaalenii_PYR-1 --FGRK-----------SSTVDAEQWTPDPVDEDTLDSD-VEIDTDED-- MSMEG_0940|M.smegmatis_MC2_155 --GTREYT---------PSGTGAEQMSPDPLDD--LDDGAPDTGLDSG-- TH_0882|M.thermoresistible__bu --ANFD------------DDADGPQERVEVAERRPWSRSTHDELFGGP-- Mb0508|M.bovis_AF2122/97 ---DRAPA---------GPPSGAEHMSPDPVEHYPDLWVDVLDTEVG--- Rv0497|M.tuberculosis_H37Rv ---DRAPA---------GPPSGAEHMSPDPVEHYPDLWVDVLDTEVG--- MMAR_0823|M.marinum_M ---DSDAA---------GQGPGAEDMSPDPVGHYGDTSVDVSDSEAES-- MUL_4567|M.ulcerans_Agy99 ---DSDAA---------GQGPGAEDMSPDPVGHYGDTSVDVSDSEAES-- MLBr_02433|M.leprae_Br4923 PVAPDSIA---------QKQSDAEGMSPDPVEPFADIPVDVMGSEVRAAE MAV_4655|M.avium_104 -PSANGTG---------RRSSGAEDMSPDPMDHYADIPVDVMDSEVREAE MAB_4012c|M.abscessus_ATCC_199 PVPPAAPSAPPATPPAPVSRPVEPEPEPEPEPEPEAVVQPEAEPEPDARP : Mflv_0078|M.gilvum_PYR-GCK TAEDAIAEEPSDTITEDAHDEDLHAEDLEPAFDDEDLDDRDSDELPSYLR Mvan_0834|M.vanbaalenii_PYR-1 LTETEIEDLDDELALRDTHDT-LIGADVEIEDEDE---DEDVDELPSYLR MSMEG_0940|M.smegmatis_MC2_155 -FEADIAD-DTGPDRRDARDA-------------------------SYPL TH_0882|M.thermoresistible__bu --TVADRDTPFDLDTDDVDDT--------------------------DLE Mb0508|M.bovis_AF2122/97 -EAEAETEVR---EAQPGR------------------------------- Rv0497|M.tuberculosis_H37Rv -EAEAETEVR---EAQPGR------------------------------- MMAR_0823|M.marinum_M -EVEDSAYVRSFLQASEGISD----------------------------- MUL_4567|M.ulcerans_Agy99 -EVEDSAYVRSFLQASEGISD----------------------------- MLBr_02433|M.leprae_Br4923 LVAEESAYARYNLQMSAGALF----------------------------- MAV_4655|M.avium_104 PALEDSAYVRSYLQSDS--------------------------------- MAB_4012c|M.abscessus_ATCC_199 EVIADEYEDDAECEEDDGEYG-------------------RSTAVEWNSH Mflv_0078|M.gilvum_PYR-GCK SSEEPLFGGQSVVDELARQGDRSSRADTVEDRDAAVETVDADETDDDLVD Mvan_0834|M.vanbaalenii_PYR-1 STEEPLFGGQTVADDLARRGRRPT------------EEHDEDE-DEDLTD MSMEG_0940|M.smegmatis_MC2_155 GS---LFGGPSVDDDLDRDLERDL-------------DREDDEYADDLAD TH_0882|M.thermoresistible__bu GDLGAEFDETDDETDLDEDLDENL---------------DEEVVEDDTAD Mb0508|M.bovis_AF2122/97 ----------------GERHAAA--------------AAAGTDVEGDGAA Rv0497|M.tuberculosis_H37Rv ----------------GERHAAA--------------AAAGTDVEGDGAA MMAR_0823|M.marinum_M ---QALYGGQSLADEVARRRGES--------------SPSTFDEEEAEAD MUL_4567|M.ulcerans_Agy99 ---QALYGGQSLADEVARRRGES--------------SPSTFDEEEAEAD MLBr_02433|M.leprae_Br4923 ---SGHTLTNELAERRGDEHAAGGLLAVG-----IDLDEDHLDLHTDLAG MAV_4655|M.avium_104 ------ALDDDLDEDLDDDHADAATLTD------EDLDAAHLEDEDAEAA MAB_4012c|M.abscessus_ATCC_199 DAEHDVEGAENDYDENDYQLEHELQELVNEHGSPVDTEASQLADVETEKK Mflv_0078|M.gilvum_PYR-GCK EPDDHDAPRT--MSPLVSALWIIGQSVIAVVFGAGLFVAFDQLWKWNNII Mvan_0834|M.vanbaalenii_PYR-1 EA--YGEPRR--MSSFVHGLWIVGQCIIAVIFGAGLFVAFDQLWKWNNII MSMEG_0940|M.smegmatis_MC2_155 ELDEDDEVDEDEGSPLVRGLWVVAQCVIAVAFGAGLFVAFDQLWKWNTIV TH_0882|M.thermoresistible__bu VG--AGEGSR--LSAILRGALVVGQCLLAVAFGAGLFLGFDQLWRWNSIV Mb0508|M.bovis_AF2122/97 EA-RVARRALDVVPTLWRGALVVLQSILAVAFGAGLFIAFDQLWRWNSIV Rv0497|M.tuberculosis_H37Rv EA-RVARRALDVVPTLWRGALVVLQSILAVAFGAGLFIAFDQLWRWNSIV MMAR_0823|M.marinum_M EE-QGARPLSGKLAALWRGTLVVLQSILAVVFGAGLFIAFDQLWRWNSIV MUL_4567|M.ulcerans_Agy99 EE-QAARPLSGKLAALWRGTLVVLQSILAVVFGAGLFIAFDQLWRWNSIV MLBr_02433|M.leprae_Br4923 IT-SPARGWQSRFEALWRGSLIVLQSILAVVFGAGLFVAFDQLWRWNSIV MAV_4655|M.avium_104 HP-APG-----RLEAIWRGSVVVLQSILAVAFGAGLFVAFDQLWRWNSIV MAB_4012c|M.abscessus_ATCC_199 TDAEAKAERKEKIKTYLQGGWIAAQYLLAAAAGAGLFFGFRELWSWNQGI . . : * ::*. *****..* :** ** : Mflv_0078|M.gilvum_PYR-GCK ALVLSVLVILGLVVGVRLVRKTEDIGSTLIAVAVGALVTLGPLAL-LQSG Mvan_0834|M.vanbaalenii_PYR-1 ALVLSVLVILGLVVGVRVVRKTEDIGSTLIAVAVGALVTLGPLAL-LQSG MSMEG_0940|M.smegmatis_MC2_155 ALVLGVLVILGLAGGVRVVRKTEDIGSTLTAVAVGALVTFGPLAL-LQAS TH_0882|M.thermoresistible__bu TLVLSMLVILGLVAGVRVVRKTEDITSTMIAVVVGALVTFGPLALQLQAS Mb0508|M.bovis_AF2122/97 ALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALITLGPLAL-LQSG Rv0497|M.tuberculosis_H37Rv ALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALITLGPLAL-LQSG MMAR_0823|M.marinum_M ALVLSVLVILGLVVGVRVVRKTEDIGSTLIAVAVGALITLGPLAL-LQSG MUL_4567|M.ulcerans_Agy99 ALVLSVLVILGLVVGVRVVRKTEDIGSTLIAVAVGALITLGPLAL-LQSG MLBr_02433|M.leprae_Br4923 ALVLSVLVILGLVVGVRVVRRTEDIASTLIAVVVGALITLGPLALSLQSG MAV_4655|M.avium_104 ALVLSVLVILGLVVGVRVVRKTEDIASTLIAVAVGALITLGPLALSLQSG MAB_4012c|M.abscessus_ATCC_199 ALVLGVLFIAILVASLWVIRKTVDLISILIAIVVGALIAFGPLVLMLQAV :***.::.* *. .: :*:* *: * : *:.****:::***.* **: Mflv_0078|M.gilvum_PYR-GCK - Mvan_0834|M.vanbaalenii_PYR-1 - MSMEG_0940|M.smegmatis_MC2_155 - TH_0882|M.thermoresistible__bu - Mb0508|M.bovis_AF2122/97 - Rv0497|M.tuberculosis_H37Rv - MMAR_0823|M.marinum_M - MUL_4567|M.ulcerans_Agy99 - MLBr_02433|M.leprae_Br4923 - MAV_4655|M.avium_104 - MAB_4012c|M.abscessus_ATCC_199 D