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PALSDSMPVPPDREDAAVVIVGAGHAGVQVAVSLREFGFSDRIVIVDAEARSPYQRPPLSKEYLCGTVDQ PPPLRAHEFYEIQRIEFRRAAAVSIDRAQRTITLDDGSRLGYGHLVLATGARNREIPVPGANTPGVLGLR TLDDARDIRERIGTSDDIVIIGAGFIGLEVAAAARKRGKRVHVVEAVDRVMARVVSPHVSQHLADLHARE GVNVHLGRSLAAIRTDRAGKLDTVELTCGTTMAADLVVVGVGVVPNIELAAEAGLAVDNGVCVDAALLTK DPAISAVGDCAAFPVSGSGASIRLESVQNAVDHGRFVAARLTGSVENYVAVPWFWTHQYSAKLQIAGKAL EVSESVVVGDAQAFSVLRFNDQTLVSVESINRPGDHLAARRILAGDKRPSPTDARSPGFSLKSFVQSATS AA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0913c | - | - | 100% (423) | pyridine nucleotide-disulphide oxidoreductase family protein |
| M. abscessus ATCC 19977 | MAB_2047c | - | 2e-75 | 41.15% (384) | ferredoxin reductase |
| M. abscessus ATCC 19977 | MAB_3838c | - | 2e-51 | 36.41% (390) | putative ferredoxin reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0707 | - | 2e-58 | 39.53% (387) | putative ferredoxin reductase |
| M. gilvum PYR-GCK | Mflv_4591 | - | 7e-78 | 43.68% (380) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
| M. tuberculosis H37Rv | Rv0688 | - | 2e-58 | 39.53% (387) | putative ferredoxin reductase |
| M. leprae Br4923 | MLBr_02387 | lpd | 4e-08 | 25.27% (186) | dihydrolipoamide dehydrogenase |
| M. marinum M | MMAR_3153 | - | 9e-79 | 43.27% (379) | ferredoxin reductase |
| M. avium 104 | MAV_4485 | - | 9e-56 | 38.54% (384) | ferredoxin reductase |
| M. smegmatis MC2 155 | MSMEG_3594 | - | 9e-61 | 40.28% (355) | anthranilate dioxygenase reductase |
| M. thermoresistible (build 8) | TH_3739 | - | 2e-51 | 36.62% (385) | PUTATIVE Pyridine nucleotide-disulphide oxidoreductase |
| M. ulcerans Agy99 | MUL_0769 | - | 4e-57 | 37.41% (401) | ferredoxin reductase |
| M. vanbaalenii PYR-1 | Mvan_1327 | - | 2e-54 | 36.81% (383) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4591|M.gilvum_PYR-GCK -----MTLHR-------------AVIVGASHAGAQLAASLRQEGWD----
MMAR_3153|M.marinum_M -----MTVQR-------------AVIAGASHAGTQLAASLRREGWD----
Mb0707|M.bovis_AF2122/97 -MNAHVTSREGVN-----EFDDGIVIVGGGLAAARTAEQLRRAGYS----
Rv0688|M.tuberculosis_H37Rv -MNAHVTSREGVN-----EFDDGIVIVGGGLAAARTAEQLRRAGYS----
MUL_0769|M.ulcerans_Agy99 MYEHHVTSSEGVTQDPGATAANGIVIIGGGLAAARTAEQLRRAGYE----
MAV_4485|M.avium_104 -MSSDASAS------------NGIVIVGGGLAAARTAEQLRRSEYS----
TH_3739|M.thermoresistible__bu -----VSTT------------AGIIIVGGGLAAARTAEQLRRSEFG----
Mvan_1327|M.vanbaalenii_PYR-1 -----MSRR-------------TFVTVGAGQTAAVAARNLRRHGFD----
MSMEG_3594|M.smegmatis_MC2_155 -----MTAAS------------TFVIIGGGLAGAKAAEALRDNDFD----
MAB_0913c|M.abscessus_ATCC_199 -----MPALSDSMPVPPDREDAAVVIVGAGHAGVQVAVSLREFGFS----
MLBr_02387|M.leprae_Br4923 -----MTHYD-------------VVVLGAGPGGYVAAIRAAQLGLSTAVV
. : *.. . *
Mflv_4591|M.gilvum_PYR-GCK ----------------GEIVLVGNESALPYHRPPLSKAYLAGKCTVDELA
MMAR_3153|M.marinum_M ----------------GEIVLVGDESALPYQRPPLSKSYLADKCELAELA
Mb0707|M.bovis_AF2122/97 ----------------GRLTIVSDEVHLPYDRPPLSKEVLRSEVDD--VA
Rv0688|M.tuberculosis_H37Rv ----------------GRLTIVSDEVHLPYDRPPLSKEVLRSEVDD--VA
MUL_0769|M.ulcerans_Agy99 ----------------GQLTIVSDEVHLPYDRPPLSKEVLRSEVDD--VS
MAV_4485|M.avium_104 ----------------GPITIVSDEVHLPYDRPPLSKEVLRKEVDD--TA
TH_3739|M.thermoresistible__bu ----------------GPITIVSDEDHLPYDRPPLSKDVLSGKTDD--VT
Mvan_1327|M.vanbaalenii_PYR-1 ----------------GRIVLIGDEPHPPYQRPPLSKEFLAGTENEEGLW
MSMEG_3594|M.smegmatis_MC2_155 ----------------GQVLLFAAEEKLPYERPPLSKDYLAGKKTLDEFT
MAB_0913c|M.abscessus_ATCC_199 ----------------DRIVIVDAEARSPYQRPPLSKEYLCGTVDQP-PP
MLBr_02387|M.leprae_Br4923 EPKYWGGICLNVGCIPSKVLLHNAELAHIFTKEAKTFGISGDASFDYGIA
. : : * : : . :
Mflv_4591|M.gilvum_PYR-GCK IRNAE-----------FYTKQRIKLMD-ATVEVLDRSAGHLSLTTGD---
MMAR_3153|M.marinum_M IRNSD-----------FYAKQRIRLLD-ATVAAVDRSAGHVVLSTGD---
Mb0707|M.bovis_AF2122/97 LKPRE-----------FYDEKDIALRLGSAAVSLDTGEQTVTLADGT---
Rv0688|M.tuberculosis_H37Rv LKPRE-----------FYDEKDIALRLGSAAVSLDTGEQTVTLADGT---
MUL_0769|M.ulcerans_Agy99 LKPRE-----------WYDEKGITLRLGSAATGLDTAAQTVTLADGT---
MAV_4485|M.avium_104 LKPRQ-----------WYDDNDITLRLGSAARSLDTAAQTLTLEDGT---
TH_3739|M.thermoresistible__bu LKPAE-----------FYAENDITLLLGTAATALDPQARKLTLADGR---
Mvan_1327|M.vanbaalenii_PYR-1 ILPPK-----------WLQDNDVEIITDTTVVRVDAAARAVEFSGGA---
MSMEG_3594|M.smegmatis_MC2_155 VAAPA-----------WYRDHDVTLRLGTEVAAINPADHTVTLPDGS---
MAB_0913c|M.abscessus_ATCC_199 LRAHE-----------FYEIQRIEFRR-AAAVSIDRAQRTITLDDGS---
MLBr_02387|M.leprae_Br4923 YDRSRKVSEGRVAGVHFLMKKNKITEIHGYGRFTDANTLSVELSEGVPET
: : : : : *
Mflv_4591|M.gilvum_PYR-GCK --ALPYDKLALCTGARPRRLSIPGADLPGVCYLRTAADVAMIRERTSPGR
MMAR_3153|M.marinum_M --ALPYDKLALCTGARPRRLPTPGADLAGVFYLRTAADGEMIREAAGPGR
Mb0707|M.bovis_AF2122/97 --VLGYDELVIATGLVPRRIPS-LPDLDGIRVLRSFDESMALRKHASAAR
Rv0688|M.tuberculosis_H37Rv --VLGYDELVIATGLVPRRIPS-LPDLDGIRVLRSFDESMALRKHASAAR
MUL_0769|M.ulcerans_Agy99 --VLGYDELVIATGLVPRRIPA-FPELEGIRVLRSFDECMALRSHASAAK
MAV_4485|M.avium_104 --TLGYDELVIATGLVPRRIPT-IPDLDGIRVLRTFDESLALREHASAAQ
TH_3739|M.thermoresistible__bu --ALEYDELIIATGLVPKRIPT-LPDLEGIRVLRTYDESMALRKHAGSAR
Mvan_1327|M.vanbaalenii_PYR-1 --GLQADSVLFATGGAPRRLPVDGPRPDLVHYLRTLDDAARLAPVLTPGR
MSMEG_3594|M.smegmatis_MC2_155 --AVGYDKLLLATGSASRRLPIPGADASGVHYLRTVDDAAALDAVLTEGA
MAB_0913c|M.abscessus_ATCC_199 --RLGYGHLVLATGARNREIPVPGANTPGVLGLRTLDDARDIRERIGTSD
MLBr_02387|M.leprae_Br4923 PLKVTFNNVIIATGSKTRLVPGTLLSTN----VITYEEQILTRELP---D
: . : :.** : :. : : :
Mflv_4591|M.gilvum_PYR-GCK RAVIVGGGYIGLEAAASLRALGLEVTVLEATERVLERVTAPAVSAFFDRI
MMAR_3153|M.marinum_M RAVIVGGGYIGLETAASLRALGLEVTLLEATGRVLERVTAPEVSEFFDRI
Mb0707|M.bovis_AF2122/97 HAVVVGAGFIGCEVAASLRGLGVDVVLVEPQPAPLASVLGEQIGQLVTRL
Rv0688|M.tuberculosis_H37Rv HAVVVGAGFIGCEVAASLRGLGVDVVLVEPQPAPLASVLGEQIGQLVTRL
MUL_0769|M.ulcerans_Agy99 RAVVIGAGFIGCEVAASLRGLGVEVVLVEPQPTPLAAVLGEQIGELVARL
MAV_4485|M.avium_104 RAVIIGAGFIGCEVAASLRSLGVDVVLVEPQPTPLAAVLGQQIGELVARL
TH_3739|M.thermoresistible__bu NAVVIGAGFIGCEVAASLRGLGVHVVLVEPQPTPLAGVLGEQIGALVARL
Mvan_1327|M.vanbaalenii_PYR-1 RLAIIGAGFIGLEIAATAAAAGVEVTVLEAVPVPLARVVGPAMGEAVCRL
MSMEG_3594|M.smegmatis_MC2_155 SLAVVGAGWIGLEVAASARTRGVNVTVVEAARLPLLGALGAEVAEVFAQL
MAB_0913c|M.abscessus_ATCC_199 DIVIIGAGFIGLEVAAAARKRGKRVHVVEAVDRVMARVVSPHVSQHLADL
MLBr_02387|M.leprae_Br4923 SIVIVGAGAIGIEFGYVLKNYGVDVTIVEFLPRAMPNED-AEVSKEIEKQ
.::*.* ** * . * * ::* : :. .
Mflv_4591|M.gilvum_PYR-GCK HREEGVDIQTDALVDAMS--GDGRVREVILASG--ESIPADLVIVGIGVE
MMAR_3153|M.marinum_M HREEGVNIRTGTLVEALS--GDGRVREVILAGG--ESIPADLVIVGIGVE
Mb0707|M.bovis_AF2122/97 HRDEGVDVRTGVTVAEVR--GKGHVDAVVLTDG--TELPADLVVVGIGST
Rv0688|M.tuberculosis_H37Rv HRDEGVDVRTGVTVAEVR--GKGHVDAVVLTDG--TELPADLVVVGIGST
MUL_0769|M.ulcerans_Agy99 HRSEGVDVRTGVGVAEVR--GDGHVDTVVLADG--TQLDADLVVVGIGSH
MAV_4485|M.avium_104 HRAEGVDVRLGVGVSEVR--GDRHVEAVVLTDG--TELAADVVVIGIGSR
TH_3739|M.thermoresistible__bu HRDEGVDLRCGVGVADVR--GTGAVEKVVLDDG--TELDADLVVVGIGST
Mvan_1327|M.vanbaalenii_PYR-1 HRDNGVDIRAGVQLAGVRT-AADGVVIDIAGAA--APLEADAVVVGIGII
MSMEG_3594|M.smegmatis_MC2_155 HREHGVDLRLEQTVEEITT-ADGRATGLRLGDG--STIAADAVLVAVGAA
MAB_0913c|M.abscessus_ATCC_199 HAREGVNVHLGRSLAAIRTDRAGKLDTVELTCG--TTMAADLVVVGVGVV
MLBr_02387|M.leprae_Br4923 FKKMGIKILTGTKVESISD-NGSHVLVAVSKDGQFQELKADKVLQAIGFA
. *:.: : : . : ** *: .:*
Mflv_4591|M.gilvum_PYR-GCK PNTDLAAAAGLAID----NGVVIDDQARTTDPDIVAAGDCTSHHMARYGR
MMAR_3153|M.marinum_M PNTELAATAGLVVD----NGVVIDDQARTSDPDIVAAGDCASHDMARYGR
Mb0707|M.bovis_AF2122/97 PATEWLEGSGVEVD----NGVICDKAGRTSAPNVWALGDVAS-WRDPMGH
Rv0688|M.tuberculosis_H37Rv PATEWLEGSGVEVD----NGVICDKAGRTSAPNVWALGDVAS-WRDPMGH
MUL_0769|M.ulcerans_Agy99 PATGWLDGSGIAVD----NGVVCDAAGRTSAPNVWAFGDVAS-WRDQMGH
MAV_4485|M.avium_104 PATDWLEGSGVAIDSVD-RGVLCDEAGRTSAPNVWALGDVAS-WRDATGH
TH_3739|M.thermoresistible__bu PATDWLQGSGVEVD----NGVVCDAVGRTNVEHVWAIGDVAS-WRNTVGK
Mvan_1327|M.vanbaalenii_PYR-1 PNTAVAAASGLWVD----DGIVVDALGRTAVPGVFAAGDAARRYSPRAGR
MSMEG_3594|M.smegmatis_MC2_155 PNIGLAERAGLATAD---GGVLVDASLRTSDPDIYAVGDIAAAQHPLFGV
MAB_0913c|M.abscessus_ATCC_199 PNIELAAEAGLAVD----NGVCVDAALLTKDPAISAVGDCAAFPVSGSGA
MLBr_02387|M.leprae_Br4923 PNVDGYGLDKVGVALTADKAVDIDDYMQTNVSHIYAIGDVTGKLQLAHVA
* : .: * * : * ** :
Mflv_4591|M.gilvum_PYR-GCK RIR----LESVPGAGEQAKVAAATICG-KSKKVAALPWFWSDQYDVK--L
MMAR_3153|M.marinum_M RIR----LESVPSAAEQAKVAAATVCG-KSKKIAALPWFWSDQYDLK--L
Mb0707|M.bovis_AF2122/97 QAR----VEHWSNVADQARVVVPAMLGTDVPTGVVVPYFWSDQYDVK--I
Rv0688|M.tuberculosis_H37Rv QAR----VEHWSNVADQARVVVPAMLGTDVPTGVVVPYFWSDQYDVK--I
MUL_0769|M.ulcerans_Agy99 QVR----VEHWSNVADQARVVVPAMLGREVSSNVVVPYFWSDQYDVK--I
MAV_4485|M.avium_104 QGR----VEHWSNVADQARVVVPAMLGKEVPPVVVVPYFWSDQYDVK--I
TH_3739|M.thermoresistible__bu QVR----VEHWSNVADQARVLVPALLGQEVPVAATVPYFWSDQYDVK--I
Mvan_1327|M.vanbaalenii_PYR-1 HLR----LEHFDNASRQGVAVANAMLGREAPSDDPL-WFWSDQYGRN--I
MSMEG_3594|M.smegmatis_MC2_155 RIR----TEHWANALKQPAVAVAGMLGRPAEY-AELPYFFTDQYDLG--M
MAB_0913c|M.abscessus_ATCC_199 SIR----LESVQNAVDHGRFVAARLTG-SVENYVAVPWFWTHQYSAK--L
MLBr_02387|M.leprae_Br4923 EAQGVVAAEAIAGAETLALSDYRMMPRATFCQPNVASFGLTEQQARDGGY
: * .. : : :.*
Mflv_4591|M.gilvum_PYR-GCK QIAGLNTGYDEVVLSGDPTRDRDFTCFYLR--AGELIAADCINRPRDFVF
MMAR_3153|M.marinum_M QIAGLNTGYDEVVLSGDPTRERDFTCFYLR--AGELLAADCINRPRDFMF
Mb0707|M.bovis_AF2122/97 QCLG-EPHATDVVHLV-EDDGRKFLAYYER--DGVLVGVVGGGMAGKVMK
Rv0688|M.tuberculosis_H37Rv QCLG-EPHATDVVHLV-EDDGRKFLAYYER--DGVLVGVVGGGMAGKVMK
MUL_0769|M.ulcerans_Agy99 QCLG-EPHSTDVVHLV-EDDGRKLLAYYQR--DGVLVGVVGGGVPGKVMK
MAV_4485|M.avium_104 QCLG-EPEADDIVHIV-EDDGRKFLAYYER--DGALVGVVGGGMPGKVMK
TH_3739|M.thermoresistible__bu QCLG-EPEAGDTVHVV-SDDGRKFLAYYER--DGVLTGVVGGGMPGKVMK
Mvan_1327|M.vanbaalenii_PYR-1 QFVG-TASGTPVIRGN-RDE-FDFTGFYLE--NDTVCGAFAIDRGEDVTA
MSMEG_3594|M.smegmatis_MC2_155 EYAGHAPSYERVVFRG-DVPGREFVSFWLDG-DNRVLAGMNVNIWDVLDD
MAB_0913c|M.abscessus_ATCC_199 QIAGKALEVSESVVVG-DAQAFSVLRFNDQ----TLVSVESINRPGDHLA
MLBr_02387|M.leprae_Br4923 DVVVAKFPFTANAKAHGMGDPSGFVKLVADAKYGELLGGHMIGHNVSELL
: . : . .
Mflv_4591|M.gilvum_PYR-GCK SKRVITQQVPIERAELMLAGPA----------------------------
MMAR_3153|M.marinum_M SKRVITQQVAVERAELVLAGSD----------------------------
Mb0707|M.bovis_AF2122/97 VRGKIAAGAPIAEVLDQTQA------------------------------
Rv0688|M.tuberculosis_H37Rv VRGKIAAGAPIAEVLDQTQA------------------------------
MUL_0769|M.ulcerans_Agy99 VRAKIAAAVPISEMLDESQGQTSARIPARGAGPGGPLVRWPTLTKSGRWR
MAV_4485|M.avium_104 TRAKIAAAVPIAEMLG----------------------------------
TH_3739|M.thermoresistible__bu ARAKIAAGAPISEVLE----------------------------------
Mvan_1327|M.vanbaalenii_PYR-1 ARELLGRGVDAAALLDEDTDLWDLVYADEDEQVRA---------------
MSMEG_3594|M.smegmatis_MC2_155 VKALIRSREPVDPDLLADPGRPLNAPG-----------------------
MAB_0913c|M.abscessus_ATCC_199 ARRILAGDKRPSPTDARSPGFSLKSFVQSATSAA----------------
MLBr_02387|M.leprae_Br4923 PELTLAQKWDLTATELVRNVHTHPTLSEALQECFHGLIGHMINF------
. :
Mflv_4591|M.gilvum_PYR-GCK ----------------------------------
MMAR_3153|M.marinum_M ----------------------------------
Mb0707|M.bovis_AF2122/97 ----------------------------------
Rv0688|M.tuberculosis_H37Rv ----------------------------------
MUL_0769|M.ulcerans_Agy99 AEKATASSPVARVDGIGLEPGPRRTASWPDVPGT
MAV_4485|M.avium_104 ----------------------------------
TH_3739|M.thermoresistible__bu ----------------------------------
Mvan_1327|M.vanbaalenii_PYR-1 ----------------------------------
MSMEG_3594|M.smegmatis_MC2_155 ----------------------------------
MAB_0913c|M.abscessus_ATCC_199 ----------------------------------
MLBr_02387|M.leprae_Br4923 ----------------------------------