For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3739 | - | - | 100% (392) | Pyridine nucleotide-disulphide oxidoreductase |
M. thermoresistible (build 8) | TH_4286 | - | 2e-66 | 40.10% (384) | PUTATIVE putative dihydrodipicolinate reductase |
M. thermoresistible (build 8) | TH_4200 | - | 3e-13 | 31.55% (187) | PUTATIVE dihydrolipoamide dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0707 | - | 1e-172 | 76.68% (386) | putative ferredoxin reductase |
M. gilvum PYR-GCK | Mflv_5068 | - | 1e-171 | 74.94% (387) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
M. tuberculosis H37Rv | Rv0688 | - | 1e-172 | 76.68% (386) | putative ferredoxin reductase |
M. leprae Br4923 | MLBr_02387 | lpd | 3e-12 | 32.07% (184) | dihydrolipoamide dehydrogenase |
M. abscessus ATCC 19977 | MAB_3838c | - | 1e-151 | 70.18% (389) | putative ferredoxin reductase |
M. marinum M | MMAR_1017 | - | 1e-170 | 75.91% (386) | ferredoxin reductase |
M. avium 104 | MAV_4485 | - | 1e-169 | 74.74% (392) | ferredoxin reductase |
M. smegmatis MC2 155 | MSMEG_1416 | - | 1e-177 | 79.07% (387) | pyridine nucleotide-disulphide oxidoreductase |
M. ulcerans Agy99 | MUL_0769 | - | 1e-168 | 75.39% (386) | ferredoxin reductase |
M. vanbaalenii PYR-1 | Mvan_1290 | - | 1e-173 | 77.00% (387) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0707|M.bovis_AF2122/97 ------MNAHVTSREGVN-----EFDDGIVIVG----GGLAAARTAEQLR Rv0688|M.tuberculosis_H37Rv ------MNAHVTSREGVN-----EFDDGIVIVG----GGLAAARTAEQLR MMAR_1017|M.marinum_M -----MYEHHVTSSEGVTQDPGATAANGIVIIG----GGLAAARTAEQLR MUL_0769|M.ulcerans_Agy99 -----MYEHHVTSSEGVTQDPGATAANGIVIIG----GGLAAARTAEQLR MAV_4485|M.avium_104 ------MSSDASAS------------NGIVIVG----GGLAAARTAEQLR Mflv_5068|M.gilvum_PYR-GCK -----MGTSEVSGGSG-----------GVVIVG----GGLAAARTAEQLR Mvan_1290|M.vanbaalenii_PYR-1 -----MTTSEVSGG--------------VVIVG----GGLAAARTAEQLR MSMEG_1416|M.smegmatis_MC2_155 -----MTTSAHSAG--------------IVIVG----GGLAATRTAEQLR TH_3739|M.thermoresistible__bu --------VSTTAG--------------IIIVG----GGLAAARTAEQLR MAB_3838c|M.abscessus_ATCC_199 -------MTDAERG--------------VLIIG----GGLGAVRTAEQLR MLBr_02387|M.leprae_Br4923 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAVVEPKYWGGICLNVGCIPSK :: **: . : Mb0707|M.bovis_AF2122/97 RAGYSGRLTIVSDEVHLPYDRP---PLSKEVLR---SEVDDVALKPREFY Rv0688|M.tuberculosis_H37Rv RAGYSGRLTIVSDEVHLPYDRP---PLSKEVLR---SEVDDVALKPREFY MMAR_1017|M.marinum_M RAGYEGQLTIVSDEVHLPYDRP---PLSKEVLR---SEVDDVSLKPREWY MUL_0769|M.ulcerans_Agy99 RAGYEGQLTIVSDEVHLPYDRP---PLSKEVLR---SEVDDVSLKPREWY MAV_4485|M.avium_104 RSEYSGPITIVSDEVHLPYDRP---PLSKEVLR---KEVDDTALKPRQWY Mflv_5068|M.gilvum_PYR-GCK RAEYPGAITIVSDEDHLPYDRP---PLSKEVLR---AETDDVTLKPAEFY Mvan_1290|M.vanbaalenii_PYR-1 RSEYAGAITIVSDEGHLPYDRP---PLSKEVLR---AETDDVTLKPAEFY MSMEG_1416|M.smegmatis_MC2_155 RSEYAGPITIVSDEDHLPYDRP---PLSKEVLR---AENDDVTLKPAEFY TH_3739|M.thermoresistible__bu RSEFGGPITIVSDEDHLPYDRP---PLSKDVLS---GKTDDVTLKPAEFY MAB_3838c|M.abscessus_ATCC_199 RAEFTGPITIVSSETHLPYDRP---PLSKDVLRDAEKTIDAVVLKPREFY MLBr_02387|M.leprae_Br4923 VLLHNAELAHIFTKEAKTFGISGDASFDYGIAYDRSRKVSEGRVAGVHFL . . :: : : .:. . .:. : . : .: Mb0707|M.bovis_AF2122/97 DEKDIALRLGSAAVSLDTGEQTVTLADGT-----VLGYDELVIATGLVPR Rv0688|M.tuberculosis_H37Rv DEKDIALRLGSAAVSLDTGEQTVTLADGT-----VLGYDELVIATGLVPR MMAR_1017|M.marinum_M DEKDIALRLGSAATGLDTAAQTVTLADGT-----VLGYDELVIATGLVPR MUL_0769|M.ulcerans_Agy99 DEKGITLRLGSAATGLDTAAQTVTLADGT-----VLGYDELVIATGLVPR MAV_4485|M.avium_104 DDNDITLRLGSAARSLDTAAQTLTLEDGT-----TLGYDELVIATGLVPR Mflv_5068|M.gilvum_PYR-GCK DENNITVLLGNGAKSVDTAAQTLTLADGS-----TLGYDELVIATGLVPK Mvan_1290|M.vanbaalenii_PYR-1 TENNITVLLGNGAKSVDTDSRTLTLADGT-----QLGYDELIIATGLVPK MSMEG_1416|M.smegmatis_MC2_155 EENNITLRLGSGAQSVDTAAQTVRLADGS-----ELPYDELVIATGLVPK TH_3739|M.thermoresistible__bu AENDITLLLGTAATALDPQARKLTLADGR-----ALEYDELIIATGLVPK MAB_3838c|M.abscessus_ATCC_199 DEKQIELRLGSEVTALDPVARTVTLSDGG-----TLEYGEVIIATGLVPR MLBr_02387|M.leprae_Br4923 MKKNKITEIHGYGRFTDANTLSVELSEGVPETPLKVTFNNVIIATGSKTR .: : *. .: * :* : :.:::**** .: Mb0707|M.bovis_AF2122/97 RIP-SLPDLDGIRVLRSFDESMALRKHASAARHAVVVGAGFIGCEVAASL Rv0688|M.tuberculosis_H37Rv RIP-SLPDLDGIRVLRSFDESMALRKHASAARHAVVVGAGFIGCEVAASL MMAR_1017|M.marinum_M RIP-AFPELEGIRVLRSFDECMALRSHASAAKRAVVIGAGFIGCEVAASL MUL_0769|M.ulcerans_Agy99 RIP-AFPELEGIRVLRSFDECMALRSHASAAKRAVVIGAGFIGCEVAASL MAV_4485|M.avium_104 RIP-TIPDLDGIRVLRTFDESLALREHASAAQRAVIIGAGFIGCEVAASL Mflv_5068|M.gilvum_PYR-GCK RIP-SFPDLPGIHVLRNFDESLALRREAASASRAVVVGAGFIGCEVAASL Mvan_1290|M.vanbaalenii_PYR-1 RIP-SFPDLPGIHVLRNFDESLALRQEAGTARRAVVVGAGFIGCEVAASL MSMEG_1416|M.smegmatis_MC2_155 RIG-SFPDLQGIRVLRTYDESMALREDARKASRAVVIGAGFIGCEVAASL TH_3739|M.thermoresistible__bu RIP-TLPDLEGIRVLRTYDESMALRKHAGSARNAVVIGAGFIGCEVAASL MAB_3838c|M.abscessus_ATCC_199 RIP-TFPDLAGVHVLRTADDSFALRGDAENARRAVVVGAGFIGCEVAATL MLBr_02387|M.leprae_Br4923 LVPGTLLSTN----VITYEEQILTRELP---DSIVIVGAGAIGIEFGYVL : :: . : . :: : * . *::*** ** *.. * Mb0707|M.bovis_AF2122/97 RGLGVDVVLVEPQPAPLASVLGEQIGQLVTRLHRDEGVDVRTGVTVAEVR Rv0688|M.tuberculosis_H37Rv RGLGVDVVLVEPQPAPLASVLGEQIGQLVTRLHRDEGVDVRTGVTVAEVR MMAR_1017|M.marinum_M RGLGVEVVLVEPQPTPLAAVLGEQIGELVARLHRSEGVDVRTGVGVAEVR MUL_0769|M.ulcerans_Agy99 RGLGVEVVLVEPQPTPLAAVLGEQIGELVARLHRSEGVDVRTGVGVAEVR MAV_4485|M.avium_104 RSLGVDVVLVEPQPTPLAAVLGQQIGELVARLHRAEGVDVRLGVGVSEVR Mflv_5068|M.gilvum_PYR-GCK RKLGVEVTLVEPQPAPLASILGQQIGDLVTRLHRAEGVDVRCGVGVSEVS Mvan_1290|M.vanbaalenii_PYR-1 RKLGVEVVLVEPQPAPLASVLGQQIGELVTRLHRAEGVDVRCGVGVSKVS MSMEG_1416|M.smegmatis_MC2_155 RKLGVDVVLVEPQPTPLASVLGEKIGALVTRLHRAEGVDVRCGVGVTEVR TH_3739|M.thermoresistible__bu RGLGVHVVLVEPQPTPLAGVLGEQIGALVARLHRDEGVDLRCGVGVADVR MAB_3838c|M.abscessus_ATCC_199 RANGVEVVLVEPQPAPLLAAIGQQLGDLVARLHRNEGVDVRVGVGVDAVE MLBr_02387|M.leprae_Br4923 KNYGVDVTIVEFLPRAMPNED-AEVSKEIEKQFKKMGIKILTGTKVESIS : **.*.:** * .: ::. : : .: *:.: *. * : Mb0707|M.bovis_AF2122/97 GKG-HVDAVVLTDG--TELPADLVVVGIGSTPATE--WLEGSGVEVD--- Rv0688|M.tuberculosis_H37Rv GKG-HVDAVVLTDG--TELPADLVVVGIGSTPATE--WLEGSGVEVD--- MMAR_1017|M.marinum_M GDG-HVDTVVLADG--TQLDADLVVVGIGSHPATG--WLDGSGIAVD--- MUL_0769|M.ulcerans_Agy99 GDG-HVDTVVLADG--TQLDADLVVVGIGSHPATG--WLDGSGIAVD--- MAV_4485|M.avium_104 GDR-HVEAVVLTDG--TELAADVVVIGIGSRPATD--WLEGSGVAIDSVD Mflv_5068|M.gilvum_PYR-GCK GDD-RVRKVTLGDG--TDVEADVVIVGIGSHPATS--WLEGSGLELD--- Mvan_1290|M.vanbaalenii_PYR-1 GDD-RVRKVTLGDG--TELDADIVVVGIGSHPATE--WLADSGLEID--- MSMEG_1416|M.smegmatis_MC2_155 GTQ-NVETVVLADG--TELEADLVIVGIGSRPSVD--WLKGSGIEVD--- TH_3739|M.thermoresistible__bu GTG-AVEKVVLDDG--TELDADLVVVGIGSTPATD--WLQGSGVEVD--- MAB_3838c|M.abscessus_ATCC_199 GQD-RVQSVTLSDG--TRLDTDLVVLGIGSRPAID--WLDGSGVAVD--- MLBr_02387|M.leprae_Br4923 DNGSHVLVAVSKDGQFQELKADKVLQAIGFAPNVDGYGLDKVGVALT-AD . * .. ** : :* *: .** * * *: : Mb0707|M.bovis_AF2122/97 NGVICDKAGRTSAPNVWALGDVA-----SWRDPMGHQARVEHWS-----N Rv0688|M.tuberculosis_H37Rv NGVICDKAGRTSAPNVWALGDVA-----SWRDPMGHQARVEHWS-----N MMAR_1017|M.marinum_M NGVVCDAAGRTSAPNVWALGDVA-----SWRDQMGHQVRVEHWS-----N MUL_0769|M.ulcerans_Agy99 NGVVCDAAGRTSAPNVWAFGDVA-----SWRDQMGHQVRVEHWS-----N MAV_4485|M.avium_104 RGVLCDEAGRTSAPNVWALGDVA-----SWRDATGHQGRVEHWS-----N Mflv_5068|M.gilvum_PYR-GCK NGVVCDEAGRASAPHVWAIGDVA-----SWRDTVGGQVRVEHWS-----N Mvan_1290|M.vanbaalenii_PYR-1 NGVVCDEAGRASAPHVWAIGDVA-----SWRDNVGGQVRVEHWS-----N MSMEG_1416|M.smegmatis_MC2_155 NGVVCDEVGRTSAPHVWAIGDVA-----SWRDHVGGQVRVEHWS-----N TH_3739|M.thermoresistible__bu NGVVCDAVGRTNVEHVWAIGDVA-----SWRNTVGKQVRVEHWS-----N MAB_3838c|M.abscessus_ATCC_199 NGVVCDAVGATGTPHVWALGDVA-----AWAGADGRPNRVEHWS-----N MLBr_02387|M.leprae_Br4923 KAVDIDDYMQTNVSHIYAIGDVTGKLQLAHVAEAQGVVAAEAIAGAETLA ..* * :.. :::*:***: : .* : Mb0707|M.bovis_AF2122/97 VADQARVVVPAMLGTDVPT-GVVVPYFWSDQYDVKIQCLGEPHATDVVHL Rv0688|M.tuberculosis_H37Rv VADQARVVVPAMLGTDVPT-GVVVPYFWSDQYDVKIQCLGEPHATDVVHL MMAR_1017|M.marinum_M VADQARVVVPAMLGREVSS-NVVVPYFWSDQYDVKIQCLGEPHSTDVVHL MUL_0769|M.ulcerans_Agy99 VADQARVVVPAMLGREVSS-NVVVPYFWSDQYDVKIQCLGEPHSTDVVHL MAV_4485|M.avium_104 VADQARVVVPAMLGKEVPP-VVVVPYFWSDQYDVKIQCLGEPEADDIVHI Mflv_5068|M.gilvum_PYR-GCK VADQARVLVPTMLGQEPPA-AVSVPYFWSDQYDVKIQALGEPEATDTVHI Mvan_1290|M.vanbaalenii_PYR-1 VADQARVLVPTMLGQQPPA-AVSVPYFWSDQYDVKIQALGEPEATDTVHI MSMEG_1416|M.smegmatis_MC2_155 VADQARAMVPALLGQEASA-VVSVPYFWSDQYDVKIQCLGEPESDDTVHI TH_3739|M.thermoresistible__bu VADQARVLVPALLGQEVPV-AATVPYFWSDQYDVKIQCLGEPEAGDTVHV MAB_3838c|M.abscessus_ATCC_199 VADQVRALVPALLGQETSANTVAVPYFWSDQYDVKIQSLGHLGSSDTVHL MLBr_02387|M.leprae_Br4923 LSDYRMMPRATFCQPNVASFGLTEQQARDGGYDVVVAKFPFTANAKAHGM ::* .:: : . .. *** : : . : Mb0707|M.bovis_AF2122/97 VEDDGRKFLAYYERDGVLVG--VVGGGMAGKVMKVRGKIAAGAPIAEVLD Rv0688|M.tuberculosis_H37Rv VEDDGRKFLAYYERDGVLVG--VVGGGMAGKVMKVRGKIAAGAPIAEVLD MMAR_1017|M.marinum_M VEDDGRKFLAYYERDGVLVG--VVGGGVPGKVMKVRAKIAAAVPISEMLD MUL_0769|M.ulcerans_Agy99 VEDDGRKLLAYYQRDGVLVG--VVGGGVPGKVMKVRAKIAAAVPISEMLD MAV_4485|M.avium_104 VEDDGRKFLAYYERDGALVG--VVGGGMPGKVMKTRAKIAAAVPIAEMLG Mflv_5068|M.gilvum_PYR-GCK VEDDGRKFLAYYERDGAVVA--VVGGGFPGKVMKTRAKIAAGAPISDLLG Mvan_1290|M.vanbaalenii_PYR-1 VEDDGRKFLAYYERDGVVVG--VVGGGFPGKVMKVRAKIAAGAPISELLG MSMEG_1416|M.smegmatis_MC2_155 VEDDGRKFLAYYERDGVLVG--VVGGGMPGKVMKTRGKIAAGAPIAEVLG TH_3739|M.thermoresistible__bu VSDDGRKFLAYYERDGVLTG--VVGGGMPGKVMKARAKIAAGAPISEVLE MAB_3838c|M.abscessus_ATCC_199 ISDDGRKFLAYLERDGVLTG--VVGCGMAGPVMKMRAKIAAGTPIAEVLA MLBr_02387|M.leprae_Br4923 GDPSGFVKLVADAKYGELLGGHMIGHNVSELLPELTLAQKWDLTATELVR . .* *. : * : . ::* ... : : . :::: Mb0707|M.bovis_AF2122/97 QTQA---------------------------------------------- Rv0688|M.tuberculosis_H37Rv QTQA---------------------------------------------- MMAR_1017|M.marinum_M ESQG---------------------------------------------- MUL_0769|M.ulcerans_Agy99 ESQGQTSARIPARGAGPGGPLVRWPTLTKSGRWRAEKATASSPVARVDGI MAV_4485|M.avium_104 -------------------------------------------------- Mflv_5068|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1290|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_1416|M.smegmatis_MC2_155 G------------------------------------------------- TH_3739|M.thermoresistible__bu -------------------------------------------------- MAB_3838c|M.abscessus_ATCC_199 GS------------------------------------------------ MLBr_02387|M.leprae_Br4923 NVHTHPTLSEALQECFHGLIGHMINF------------------------ Mb0707|M.bovis_AF2122/97 ------------------ Rv0688|M.tuberculosis_H37Rv ------------------ MMAR_1017|M.marinum_M ------------------ MUL_0769|M.ulcerans_Agy99 GLEPGPRRTASWPDVPGT MAV_4485|M.avium_104 ------------------ Mflv_5068|M.gilvum_PYR-GCK ------------------ Mvan_1290|M.vanbaalenii_PYR-1 ------------------ MSMEG_1416|M.smegmatis_MC2_155 ------------------ TH_3739|M.thermoresistible__bu ------------------ MAB_3838c|M.abscessus_ATCC_199 ------------------ MLBr_02387|M.leprae_Br4923 ------------------