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MSMDRPDAHELCAAVAQRIERNEPDLTARIRAELPSYTRLSESEHRRTVHELARRLLTGIADREGPVAEH LQYTRRAALRRMQLGVSAYDMMRSFHIVSSGIWNALQTAPEANDALLLDLVEPLATWTEALTAAVVDAFI EEQPVRSVHEMKTRREFFAELGDRSRAERTAETARTLAFDVDGEFQALCSPRSVWPDTEVEMLQRTTRHL PGVVQCGVWGNVLVALVQDCDVENVLRSAQAISGASAEYGVGLARRGLAGAHQSCIDAERALRMARVQKL PAARFVDWWLEASLLDFQSQLAVLFDAVHETATKYPDLAEAVLVFADCGFSLARAARRLQVHPNSVAYRL TRWQQLSGADPRTFDGLARSVIACRLTCPV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0912 | - | - | 100% (380) | hypothetical protein MAB_0912 |
| M. abscessus ATCC 19977 | MAB_1391 | - | 9e-09 | 23.87% (377) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1880c | - | 3e-05 | 36.11% (72) | hypothetical protein MAB_1880c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2266 | - | 1e-07 | 26.67% (255) | hypothetical protein Mb2266 |
| M. gilvum PYR-GCK | Mflv_2780 | - | 1e-05 | 29.31% (116) | hypothetical protein Mflv_2780 |
| M. tuberculosis H37Rv | Rv2242 | - | 1e-07 | 26.67% (255) | hypothetical protein Rv2242 |
| M. leprae Br4923 | MLBr_01652 | - | 7e-07 | 37.88% (66) | hypothetical protein MLBr_01652 |
| M. marinum M | MMAR_3335 | - | 1e-06 | 36.36% (66) | hypothetical protein MMAR_3335 |
| M. avium 104 | MAV_4933 | - | 7e-06 | 23.65% (351) | hypothetical protein MAV_4933 |
| M. smegmatis MC2 155 | MSMEG_5120 | - | 4e-06 | 31.30% (131) | hypothetical protein MSMEG_5120 |
| M. thermoresistible (build 8) | TH_3478 | - | 1e-35 | 32.30% (356) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1307 | - | 7e-07 | 36.36% (66) | hypothetical protein MUL_1307 |
| M. vanbaalenii PYR-1 | Mvan_5765 | - | 3e-05 | 38.37% (86) | transcriptional regulator, CdaR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3335|M.marinum_M --------------------------------------------------
MUL_1307|M.ulcerans_Agy99 --------------------------------------------------
Mb2266|M.bovis_AF2122/97 --------------------------------------------------
Rv2242|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01652|M.leprae_Br4923 --------------------------------------------------
Mflv_2780|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4933|M.avium_104 --------------------------------------------------
TH_3478|M.thermoresistible__bu --------------------------------------------------
MAB_0912|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5120|M.smegmatis_MC2_155 ----------------MQAPGVSLGQLLLALDATLVRLVEAPRGLDLPVA
Mvan_5765|M.vanbaalenii_PYR-1 MSSRTLSTALPFEHWLSALAEIGEAVGGDEPVAEVLDRVARTACTLLGYD
MMAR_3335|M.marinum_M --------------------------------------MNDNQFSAIARL
MUL_1307|M.ulcerans_Agy99 --------------------------------------MNNNQFSAIARL
Mb2266|M.bovis_AF2122/97 --------------------------------------MNDNQLAPVARP
Rv2242|M.tuberculosis_H37Rv --------------------------------------MNDNQLAPVARP
MLBr_01652|M.leprae_Br4923 --------------------------------------MNHNHFVPAPPR
Mflv_2780|M.gilvum_PYR-GCK -------------------------------------MPDNNRFVPP---
MAV_4933|M.avium_104 ----------------------------MKDFRAPVNGVDGDSASALVAV
TH_3478|M.thermoresistible__bu --------------------------------------------------
MAB_0912|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5120|M.smegmatis_MC2_155 SAALIDSDDVRFGLAPAAGSADLFFLLGVSESDALAWVDHQADHRPPAAI
Mvan_5765|M.vanbaalenii_PYR-1 FCAVFLPDEQGRALTIEGSYGLSADYIAQVNANRPILLDVRGDHEAPTSL
MMAR_3335|M.marinum_M GSARSPLELLETVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQ
MUL_1307|M.ulcerans_Agy99 GSARSPLELLETVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQ
Mb2266|M.bovis_AF2122/97 ---RSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQ
Rv2242|M.tuberculosis_H37Rv ---RSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQ
MLBr_01652|M.leprae_Br4923 ---RLPLELLDTVPDSLLRRLKQYSGRLATEAVTAMQERLPFFADLEASQ
Mflv_2780|M.gilvum_PYR-GCK ---NSTVEVLGNVPDSTLRRLKQYSGRLATEAVHAMEERLPFFADMEASQ
MAV_4933|M.avium_104 PKSQGAQTIRPDSVSRLVGALLDDHAAVVGRVRSVIRSRLPVYRSVADEA
TH_3478|M.thermoresistible__bu --------------------MLDELEDIAAQVTAIIRAELPAYAAIPLDD
MAB_0912|M.abscessus_ATCC_1997 ------MSMDRPDAHELCAAVAQRIERNEPDLTARIRAELPSYTRLSESE
MSMEG_5120|M.smegmatis_MC2_155 FVKEPSQAIVERATAAGIAVVAVDTRARWERLYRLVNHVFEHHNDRALHD
Mvan_5765|M.vanbaalenii_PYR-1 AYRTGDVVTLEDIELVPDFTWGGVAQEQGYRALISAPLRRPGTVVGALNG
MMAR_3335|M.marinum_M RASVALVVQTAVVNFAEWMQNPRSDVSYTAQ-------AFELVPQDLTRR
MUL_1307|M.ulcerans_Agy99 RASVALVVQTAVVNFAEWMQNPRSDVSYTAQ-------AFELVPQDLTRR
Mb2266|M.bovis_AF2122/97 RASVALVVQTAVVNFVEWMHDPHSDVGYTAQ-------AFELVPQDLTRR
Rv2242|M.tuberculosis_H37Rv RASVALVVQTAVVNFVEWMHDPHSDVGYTAQ-------AFELVPQDLTRR
MLBr_01652|M.leprae_Br4923 RASVTLVVQTAVVNFVQWMQNPHSDVSYTAQ-------AFELVPQDLARR
Mflv_2780|M.gilvum_PYR-GCK RASVQLVVQTAVVNFVEWMRDPQSDVSYTAQ-------AFEVVPQDLRRR
MAV_4933|M.avium_104 LEAELEWVLRSAVGGREALHEP-QIAGLAAI-------GEARARDGVPVD
TH_3478|M.thermoresistible__bu HRAAVQDQLSVILTGLREMRGPGPADLITAER-----LGRRRAEQGIDIS
MAB_0912|M.abscessus_ATCC_1997 HRRTVHELARRLLTGIADREGPVAEHLQYTRR-----AALRRMQLGVSAY
MSMEG_5120|M.smegmatis_MC2_155 SGTDLFGLAQSVAERTHGMVSIEDAQSHVLAY-----SASNEEADELRRL
Mvan_5765|M.vanbaalenii_PYR-1 YRTAPHRFDRAEVSLVTTLATQVAIALGTAQLRAKEQATIRELRRAEEVH
MMAR_3335|M.marinum_M IALRHT-------VDMVRVTMEFFEEVVPLLARSEEQLTALTVGILK---
MUL_1307|M.ulcerans_Agy99 IALRHT-------VDMVRVTMEFFEEVVPLLARSEEQLTALTVGILK---
Mb2266|M.bovis_AF2122/97 IALRQT-------VDMVRVTMEFFEEVVPLLARSEEQLTALTVGILK---
Rv2242|M.tuberculosis_H37Rv IALRQT-------VDMVRVTMEFFEEVVPLLARSEEQLTALTVGILK---
MLBr_01652|M.leprae_Br4923 IALRHT-------VDMVRVTMEFFEEVVPLLARSEEQLTALTVGILK---
Mflv_2780|M.gilvum_PYR-GCK IALRQS-------VEMVRTTMEYFEEVVPLLARSEDQLTALTAGILR---
MAV_4933|M.avium_104 DMLRAW-------RIGVEVVVECAREAARRLGVDDARVLELVQSALA---
TH_3478|M.thermoresistible__bu ALMRAY-------ELPLQELWQRYAGLVCD-GKQAQELIALAPSLLR---
MAB_0912|M.abscessus_ATCC_1997 DMMRSF-------HIVSSGIWN---ALQTAPEANDALLLDLVEPLAT---
MSMEG_5120|M.smegmatis_MC2_155 SILGRAGPPEHLDWIAQWGIFDALRAKPDVVRVAERPELGLRPRLAIGIF
Mvan_5765|M.vanbaalenii_PYR-1 TLLTATALRGEGVSGVAAALSELLGRGVLIEDVYDEPLTDANWTAPDPRA
: :
MMAR_3335|M.marinum_M ----------------YSRDLAFTAASAYADA----------------AE
MUL_1307|M.ulcerans_Agy99 ----------------YSRDLAFTAASAYADA----------------AE
Mb2266|M.bovis_AF2122/97 ----------------YSRDLAFTAATAYADA----------------AE
Rv2242|M.tuberculosis_H37Rv ----------------YSRDLAFTAATAYADA----------------AE
MLBr_01652|M.leprae_Br4923 ----------------YSRDLAFTAATAYADA----------------AE
Mflv_2780|M.gilvum_PYR-GCK ----------------YSRDLAFAAASAYADQ----------------AE
MAV_4933|M.avium_104 ----------------WSDIAMATSAKAHRRT----------------ER
TH_3478|M.thermoresistible__bu ----------------WLHQLGGAAATGHQIV----------------TT
MAB_0912|M.abscessus_ATCC_1997 ----------------WTEALTAAVVDAFIEE----------------QP
MSMEG_5120|M.smegmatis_MC2_155 QPAPDERRAPTFAGTIWVQQGSRPLAEDAEEV----------------LR
Mvan_5765|M.vanbaalenii_PYR-1 QDHVVATVTLDGSPVARIHVAASDSELSRLDVRAVEHATVVTALELLRAR
MMAR_3335|M.marinum_M ARGTWDSRMEASVVDAVVRGDT-------------GPELLSRAAALNWDT
MUL_1307|M.ulcerans_Agy99 ARGTWDSRMEASVVDAVVRGDT-------------GPELLSRAAALNWDT
Mb2266|M.bovis_AF2122/97 ARGTWDSRMEASVVDAVVRGDT-------------GPELLSRAAALNWDT
Rv2242|M.tuberculosis_H37Rv ARGTWDSRMEASVVDAVVRGDT-------------GPELLSRAAALNWDT
MLBr_01652|M.leprae_Br4923 ARGTWDSRMEASVVDAVVRGDT-------------GPELLSRAAALNWDT
Mflv_2780|M.gilvum_PYR-GCK ARGAWDTRIESNLVDAVVRGDI-------------GPDLQSQAAALNWDA
MAV_4933|M.avium_104 ALALEAEESDAEFVRGALMGSL-------------PAAELRMHAELRGLD
TH_3478|M.thermoresistible__bu SQLANEVRLQAQLLDLITADPA-------------GAQTLVLAGRLGLDT
MAB_0912|M.abscessus_ATCC_1997 VRSVHEMKTRREFFAELGDRSR-------------AERTAETARTLAFDV
MSMEG_5120|M.smegmatis_MC2_155 GAAVLAARIMARLAATPSSDAVRLQELLGLRATDEPVDVEQVARELGITA
Mvan_5765|M.vanbaalenii_PYR-1 TAAEVEQRIRGSLVADLLSSDDAG-----------IPALLDRARRLGWDL
. . *
MMAR_3335|M.marinum_M TAPATVVVGTPASARDGS--DG-SERAIQDVRDAAAQHGRAALTDVHGTW
MUL_1307|M.ulcerans_Agy99 TAPATVVVGTPASARDGS--DG-SERAIQDVRDAAAQHGRAALTDVHGTW
Mb2266|M.bovis_AF2122/97 TAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAALTDVHGTW
Rv2242|M.tuberculosis_H37Rv TAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAALTDVHGTW
MLBr_01652|M.leprae_Br4923 TAPATVVVGTPTPNHDGPNGQVSSERASQEVREIAARHGRAALTDVHGTW
Mflv_2780|M.gilvum_PYR-GCK TAPATVIVGTPRPD--------RTEFVVDDVHDVVKRHGRAALSDVHGTW
MAV_4933|M.avium_104 PGAEYVAVRARLGG------DGPHLRLEQSLGFQDPAHSRRGLCALLDGD
TH_3478|M.thermoresistible__bu GGTFQAVGFTPSVDPHR--LERVIVRLRIHAGPVVAGVHDGMFVVLQQHD
MAB_0912|M.abscessus_ATCC_1997 DGEFQALCSPRSVWPDT-EVEMLQRTTRHLPGVVQCGVWGNVLVALVQDC
MSMEG_5120|M.smegmatis_MC2_155 DGRAALIGFDAGSPSTRIADVLSLSASAFRSDAQITSSRTRVYVLFPNTG
Mvan_5765|M.vanbaalenii_PYR-1 SGVQSLIALRPADERTLAAADRFTAGVTPHPLVALHRGDLVFVWPADTGP
.
MMAR_3335|M.marinum_M LVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAAYHSASEAISG
MUL_1307|M.ulcerans_Agy99 LVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAAYHSASEAISG
Mb2266|M.bovis_AF2122/97 LVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISG
Rv2242|M.tuberculosis_H37Rv LVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISG
MLBr_01652|M.leprae_Br4923 LVAIISGQLAPTDKFFSDLLHAFSDGPVVIGPTAPMLTAAYHSASEAVSG
Mflv_2780|M.gilvum_PYR-GCK LVAIVSGNLSPTDRFLAELMSVFADGPVVIGPTAATLGGAHRSATEAVAG
MAV_4933|M.avium_104 LAGFLIE--PPRD----------VEGVVGFGPPRPLTRLSESYRMAARAL
TH_3478|M.thermoresistible__bu RTGVVTQLCRPHA----------AGGVFGIGEPRYGLQGAALSIGDARR-
MAB_0912|M.abscessus_ATCC_1997 DVENVLRSAQAISG---------ASAEYGVGLARRGLAGAHQSCIDAERA
MSMEG_5120|M.smegmatis_MC2_155 KPGAVTSWLRGTVSALRAELG--IELYAVIAAPVAGLAGAAAARTEVDRV
Mvan_5765|M.vanbaalenii_PYR-1 AVPVAHRLLEFLNAATIPEAPTAAVSRQAAARELPGIFRTVRGALDLAGD
. :
MMAR_3335|M.marinum_M MNAVAGWRGAPRPVLARELLPERALMGDASAIVALHT----DVMRPLADA
MUL_1307|M.ulcerans_Agy99 MNAVAGWRGASRPVLARELLPERALMGDASAIVALHT----DVMRPLADA
Mb2266|M.bovis_AF2122/97 MNAVAGWRGAPRPVLARELLPERALMGDASAIVALHT----DVMRPLADA
Rv2242|M.tuberculosis_H37Rv MNAVAGWRGAPRPVLARELLPERALMGDASAIVALHT----DVMRPLADA
MLBr_01652|M.leprae_Br4923 MNAVAGWSGAPRPVQARELLPERALMGDASAIVALHT----DVMLPLADA
Mflv_2780|M.gilvum_PYR-GCK MNSVAGWPGAPRPVAARELLPERALLGDVTAATALEA----EVMRPLADA
MAV_4933|M.avium_104 VTAEACGLRGAYDIAALGLRTAVAIDADVGELLRKRY----LEPLSVGGS
TH_3478|M.thermoresistible__bu AAGLAAVLGHDVVFSRHWLLASVLASADHLDHLGRG--------AEIASE
MAB_0912|M.abscessus_ATCC_1997 LRMARVQKLPAARFVDWWLEAS---LLDFQSQLAVLF----DAVHETATK
MSMEG_5120|M.smegmatis_MC2_155 LDSAGRHPGALGQVTSLAEARTTVLLDEIITAIASDDRLIDPRVRALRTE
Mvan_5765|M.vanbaalenii_PYR-1 RDTATVIDLDEPTIDHLLLQLDDPARLRDFASAVLGP-----AVDYDRTR
.
MMAR_3335|M.marinum_M GPTLIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRITDFTGRDPTQP
MUL_1307|M.ulcerans_Agy99 GPTLIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRITDFTGRDPTQP
Mb2266|M.bovis_AF2122/97 GPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQP
Rv2242|M.tuberculosis_H37Rv GPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQP
MLBr_01652|M.leprae_Br4923 GPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGHDPTLP
Mflv_2780|M.gilvum_PYR-GCK GPALMDTLDAYLDSGGAIEACARKLFIHPNTVRYRLKRITDFTGRDPTVP
MAV_4933|M.avium_104 SRELIATVRTYLACGMHVERTATRLFVHQNTVRYRLARFEELTGASLRDT
TH_3478|M.thermoresistible__bu HPHLSEAVVAFAHNGFSTAAAARVLHLHPNTVSYRLDRWTQLTGWELNDF
MAB_0912|M.abscessus_ATCC_1997 YPDLAEAVLVFADCGFSLARAARRLQVHPNSVAYRLTRWQQLSGADPRTF
MSMEG_5120|M.smegmatis_MC2_155 EPVLAETLRVYLDSFGDVAAAAQSMHVHPNTVRYRVRRVEQLLGTSLGDP
Mvan_5765|M.vanbaalenii_PYR-1 STELLHTVRVLLEHGLDRRAAAQALHLHPNTVAQRVRRLEELTGLSLARP
* :: . * : :* *:: *: * :: * .
MMAR_3335|M.marinum_M RDAYVLRVAATVGQLN---YPTPPSGAANNTITPVPLPVRRGTEGP
MUL_1307|M.ulcerans_Agy99 RDAYVLRVAATVGQLN---YPTPPSGAANNTITPVPLPVRRGTEGP
Mb2266|M.bovis_AF2122/97 RDAYVLRVAATVGQLN---YPTPH----------------------
Rv2242|M.tuberculosis_H37Rv RDAYVLRVAATVGQLN---YPTPH----------------------
MLBr_01652|M.leprae_Br4923 RDAYVLRVAATVGKLN---YPTHH----------------------
Mflv_2780|M.gilvum_PYR-GCK RDAYVLRVASSLGRLTRQASQSPPLSARSGPRGGVASVTNPGTSP-
MAV_4933|M.avium_104 EVVTEVWWVLELAAMRL-----------------------------
TH_3478|M.thermoresistible__bu EGLARSVVCIALSARRASGPSATASG--------------------
MAB_0912|M.abscessus_ATCC_1997 DGLARSVIACRLTCPV------------------------------
MSMEG_5120|M.smegmatis_MC2_155 DVRLLLSLSLRATA--------------------------------
Mvan_5765|M.vanbaalenii_PYR-1 ADLLRLTAALTVSRIASLS---------------------------